June, 2023

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Octopuses rewire their brains to adapt to seasonal temperature shifts

Science Daily: Pharmacology News

Octopuses don't thermoregulate, so their powerful brains are exposed to -- and potentially threatened by -- changes in temperature. Researchers report that two-spot octopuses adapt to seasonal temperature shifts by producing different neural proteins under warm versus cool conditions. The octopuses achieve this by editing their RNA, the messenger molecule between DNA and proteins.

RNA 361
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BioMarin finally secures FDA approval of hemophilia gene therapy

BioPharma Drive: Drug Pricing

After a prolonged journey, the medicine, known as Roctavian, is now cleared for certain patients with hemophilia A, the more common form of the rare bleeding disorder.

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AHA News: Beat the Heat With Hydrating Foods This Summer

Drugs.com

TUESDAY, June 20, 2023 (American Heart Association News) -- Staying hydrated can help you live a longer, healthier life. But drinking multiple glasses of water throughout the day isn't for everyone. Health experts say that's OK. While fluids are.

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Recent Highlights in Targeted Protein Degradation

Drug Hunter

In Wednesday’s Flash Talk webinar , we covered recent highlights in targeted protein degradation, with lots of great questions from the audience. The webinar and recording are available below to everyone thanks to our sponsor, Revvity Signals, and the slides are available for download to Premium members at the bottom. The talk covered: Theoretical advantages of targeted protein degradation over traditional small molecules Recent highlights throughout the industry illustrating these advanta

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Bridging Innovation & Patient Care: The Growing Role of AI

Speaker: Simran Kaur, Co-founder & CEO at Tattva.Health

AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!

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First Duchenne gene therapy approved by FDA for young children

BioPharma Drive: Drug Pricing

The conditional clearance for Sarepta’s Elevidys in 4- and 5-year-olds is a milestone for research into the deadly disease, and raises the stakes of an ongoing trial that could prove how well it works.

Therapies 319

More Trending

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FDA sets decision dates for Vertex, CRISPR gene editing drug

BioPharma Drive: Drug Pricing

The regulator will issue separate verdicts on the pioneering treatment’s use in sickle cell disease and beta thalassemia, with the first expected late this year.

FDA 315
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Verve partners with Lilly on gene editing therapy for heart disease

BioPharma Drive: Drug Pricing

Lilly will pay the genetic medicine specialist $60 million upfront to work together on a treatment targeting a risk factor known as Lp(a).

Therapies 310
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FDA panel backs full approval for Eisai, Biogen Alzheimer’s drug

BioPharma Drive: Drug Pricing

In a 6-0 vote, a group of independent advisers agreed recent clinical trial data confirmed the drug’s benefit, paving the way for an FDA decision early next month.

FDA 309
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Clean, sustainable fuels made 'from thin air' and plastic waste

Science Daily: Pharmacology News

Researchers have demonstrated how carbon dioxide can be captured from industrial processes -- or even directly from the air -- and transformed into clean, sustainable fuels using just the energy from the Sun.

Research 302
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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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When Your Child Has Scoliosis: Symptoms & Treatments

Drugs.com

FRIDAY, June 23, 2023 -- The future for a child diagnosed with scoliosis, an abnormal curvature of the spine that typically occurs just before puberty, can feel uncertain. As a parent, you want answers to your questions about scoliosis and how it.

Treatment 299
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Don't Get (Sun)Burned This 4th of July Weekend

Drugs.com

FRIDAY, June 30, 2023 -- Adding sun protection to your holiday gatherings takes little effort and can help you avoid the pain and potential side effects of sunburn. As Americans prepare to celebrate July 4 with parades, swimming and cookouts, the.

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Most Women With Early Breast Cancer Will Become Long-Term Survivors, New Study Shows

Drugs.com

WEDNESDAY, June 14, 2023 -- Most women diagnosed with early breast cancer will become long-term survivors, according to new research that finds a substantial reduction in the risk of death since the 1990s. This news should reassure both patients and.

Research 299
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Experts Warn of Heart Dangers From Smoke of Canadian Wildfires

Drugs.com

THURSDAY, June 8, 2023 -- As a huge plume of smoke from over 400 Canadian wildfires swept south and turned New York City into a landscape that resembled Mars more than Earth, heart experts warned that air pollution can damage your heart as much as.

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How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

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Alzheimer’s Stages: Mild, Moderate & Severe

Drugs.com

WEDNESDAY, June 14, 2023 -- When a loved one is diagnosed with Alzheimer's disease, it can be a challenging and emotional journey for the individual and their family. Understanding the progression of the disease and recognizing the changes in.

Disease 298
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FDA Approves Linzess to Treat Constipation in Children, Teens

Drugs.com

WEDNESDAY, June 14, 2023 -- The U.S. Food and Drug Administration approved Linzess (linaclotide) as a once-daily treatment for pediatric patients ages 6 to 17 years with functional constipation. The approval was based on data from 328 participants.

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Legalizing Marijuana Tied to More Binge Drinking in Folks Over 30

Drugs.com

WEDNESDAY, June 21, 2023 -- A growing number of states are legalizing marijuana for recreational use, and it may be leading to an unexpected side effect among millennials and Gen Xers: binge drinking. Binge drinking is defined as five or more drinks.

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FDA Orders Stores to Stop Selling Elf Bar Disposable Vapes

Drugs.com

FRIDAY, June 23, 2023 -- The U.S. Food and Drug Administration said Thursday it has sent warning letters to 189 retailers, telling them to stop selling unauthorized tobacco products such as Elf Bar and Esco Bars. Both brands are disposable.

FDA 297
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Deliver Fast, Flexible Clinical Trial Insights with Spotfire

Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

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Fixing a Painful Joint Problem Won't Ease Mental Health Ills, Study Finds

Drugs.com

FRIDAY, June 30, 2023 -- Blaming your ailing knees for feeling down? Unfortunately, even after physical pain eases, healing or fixing an injured joint often does not improve mental health, research shows. A new study found that anxiety symptoms only.

Research 297
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New Approach to Transplants Could Boost Supply of Donor Hearts

Drugs.com

THURSDAY, June 8, 2023 -- A new transplant method that "reanimates" donor hearts appears safe and effective, a new clinical trial has found — in an advance that could substantially expand the supply of donor hearts available in the United.

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Cirrhosis of the Liver: Causes, Symptoms & Treatment

Drugs.com

TUESDAY, June 20, 2023 -- Cirrhosis of the liver poses a significant health challenge worldwide. With no known cure, it requires comprehensive management to slow liver damage, alleviate symptoms and prevent potential complications. Cirrhosis is.

Treatment 295
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Is Child's Tummy Pain a Serious Concern? Poll Finds Many Parents Unsure

Drugs.com

MONDAY, June 19, 2023 -- Kids get a lot of tummy aches. How a parent responds to it can vary, just as the causes can, according to the University of Michigan Health's C.S. Mott Children’s Hospital National Poll on Children’s Health, which looked.

Hospitals 295
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Clinical Data Like You´ve Never Seen It Before: Why Spotfire Is the Leading Tool for Clinical Analytics

Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

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UniQure stock tumbles on ‘confusing’ results for Huntington’s gene therapy

BioPharma Drive: Drug Pricing

While treated patients appear to be doing better than history suggests they would, mixed findings involving a key surrogate marker perplexed Wall Street analysts and sent shares falling 38%.

Therapies 294
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Lesbians, Gays Suffer More Mental Health Issues, Drug Use Problems: Survey

Drugs.com

WEDNESDAY, June 14, 2023 -- Lesbians, gays and bisexuals are experiencing more mental health and substance use issues than their heterosexual peers, researchers say. According to a new government report released Tuesday, this includes major.

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CDC Gives Full Approval to RSV Shots, Arexvy and Abrysvo, for People Over 60; Vaccines Available This Fall

Drugs.com

THURSDAY, June 29, 2023 -- Americans ages 60 and up can get their vaccine for respiratory syncytial virus (RSV) this fall, the U.S. Centers for Disease Control and Prevention announced Thursday. On Thursday, Dr. Rochelle Walensky, the outgoing CDC.

Vaccine 290
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FDA Advisers Say Next Round of COVID Booster Shots Should  Target an XBB Variant

Drugs.com

THURSDAY, June 15, 2023 -- An advisory panel to the U.S. Food and Drug Administration voted unanimously on Thursday to recommend that COVID booster shots be updated for the fall to protect solely against one of the three XBB variants that have taken.

FDA 290
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Sarepta prices Duchenne gene therapy at $3.2M

BioPharma Drive: Drug Pricing

The cost makes Sarepta’s treatment, called Elevidys, among the most expensive medicines in the world. But company executives said they don’t expect significant insurer pushback.

Therapies 287