Medicare names first 10 drugs for price negotiations
BioPharma Drive: Drug Pricing
AUGUST 29, 2023
The list includes the top-selling blood thinners Eliquis and Xarelto, as well as the arthritis drug Enbrel and heart failure medicine Entresto.
BioPharma Drive: Drug Pricing
AUGUST 29, 2023
The list includes the top-selling blood thinners Eliquis and Xarelto, as well as the arthritis drug Enbrel and heart failure medicine Entresto.
Drug Discovery World
AUGUST 29, 2023
The pharmaceutical industry continues to maintain strong levels of public trust and favourability in the UK, according to data from the Association of the British Pharmaceutical Industry (ABPI). Opinions showed consistent recognition of the sector’s support for the NHS, with 67% of respondents saying the industry is committed to developing new medicines to meet patient needs.
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Broad Institute
AUGUST 31, 2023
Evolved prime editors are smaller and more efficient for therapeutic applications By Corie Lok August 31, 2023 Breadcrumb Home Evolved prime editors are smaller and more efficient for therapeutic applications Researchers have evolved the editing machine at the heart of the prime editing system, which can make a wide range of changes to the genome. By Sarah C.P.
Drugs.com
AUGUST 31, 2023
THURSDAY, Aug. 31, 2023 – The U.S. Department of Health and Human Services has asked the U.S. Drug Enforcement Agency to reclassify marijuana as a less dangerous drug under the Controlled Substances Act, a move that could potentially expand.
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Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.
Antidote
AUGUST 30, 2023
At the outset, many people may experience apprehension when considering joining a clinical trial. Opting to participate in a research study is a personal one — but it can also be quite gratifying. Various types of clinical studies play a pivotal role in ensuring the approval of life-saving medications and treatments. For this to happen, we need volunteers to take part.
Perficient: Drug Development
AUGUST 31, 2023
Responsibilities, Skills, Scope and More. The tutorial provides basic concepts of Kotlin. Our Kotlin tutorial includes. What is Kotlin? Pre-Requisites Features of Kotlin Kotlin Architecture What is Kotlin? Kotlin is a programming language introduced by JetBrains in 2011. Kotlin is free, has been free and will remain free. It is developed under the Apache 2.0 license.
Drug Discovery Digest brings together the best content for drug research and development professionals from the widest variety of industry thought leaders.
Drug Discovery World
AUGUST 25, 2023
DDW’s Megan Thomas looks at a day in the life of Giusy Di Conza , Head of Research at iOnctura. MT: Where do you work, and can you tell us what you’re working on at the moment? GDC : I’m Head of Research for a young, dynamic biotech called iOnctura. We are pioneering research into new biological mechanisms for established drug targets. Whereas traditionally biotechs have studied the effect of a drug on a singular pathway, we are focused on targets that are involved in multiple independent tumour
Drug Target Review
AUGUST 31, 2023
In the pursuit of a remedy for Alzheimer’s disease, a frontier in medical science is illuminating a glimmer of hope. Stem cell therapies have already demonstrated their prowess in treating diverse cancers and ailments linked to the blood and immune system. In an innovative proof-of-concept investigation, researchers at the University of California San Diego have revealed the potential of stem cell transplants as a promising therapeutic avenue against Alzheimer’s disease.
Drugs.com
AUGUST 30, 2023
WEDNESDAY, Aug. 30, 2023 -- Narcan, a lifesaving medication that reverses opioid overdose, will be available on U.S. drugstore shelves and online starting next week. People who want to carry Narcan, the nasal spray version of naloxone, will be able.
Translation
AUGUST 31, 2023
Halo was proud to host Bayer Crop Science ’s third year of Grants4Ag. Grants4Ag is Bayer’s annual initiative providing funding and expertise to researchers developing novel solutions in agriculture. As part of Bayer’s CropKey approach to crop protection innovation, this year’s awards focused on transformative R&D and breakthrough technologies for next-gen crop protection solutions.
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Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.
Perficient: Drug Development
AUGUST 28, 2023
Introduction to Feign Client: In the world of software, microservices are like building blocks that help make programs more flexible and scalable. But for these blocks to work together, they need to talk to each other effectively. Imagine each block sharing information, asking for help, and working together smoothly. Meet Feign Client, a super useful tool for microservices.
BioPharma Drive: Drug Pricing
AUGUST 29, 2023
A broadened clearance for Reblozyl in myelodysplastic syndromes should help Bristol Myers offset the looming loss of revenue from top-selling medicines set to soon lose market exclusivity.
Drug Discovery World
AUGUST 25, 2023
As negotiations continue between the UK and EU over Horizon Europe, the largest collaborative research programme in the world, the scientific research community has urged the Prime Minister to secure the UK’s membership as soon as possible. Figures reported in The Guardian from the European Commission emphasise the importance of the programme to UK research.
FDA Law Blog: Biosimilars
AUGUST 24, 2023
Hyman, Phelps & McNamara, P.C. (“HP&M”) is is proud to announce that 14 of the Firm’s attorneys have been selected to the 2024 edition of The Best Lawyers in America®. Newly recognized this year are attorneys Josephine M. Torrente (FDA Law), Michelle L. Butler (FDA Law), Sara W. Koblitz (FDA Law), Allyson B. Mullen (FDA Law), and Anne K. Walsh (FDA Law), as well as McKenzie E.
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Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic
Drugs.com
AUGUST 30, 2023
WEDNESDAY, Aug. 30, 2023 -- Sudden cardiac arrest may not come on so suddenly after all. Fully 50% of people who experienced a sudden cardiac arrest had a telling symptom 24 hours before, and these symptoms are different in men than women, a new.
Antidote
AUGUST 21, 2023
Before any new treatment is able to be approved, it is required to go through the vigorous testing process known as clinical trials. These trials are aimed at determining whether or not a drug, medical device, therapy, or other type of intervention is safe and effective for the public.
Perficient: Drug Development
AUGUST 28, 2023
An innovation wildcard is a team member who is there to add a unique perspective that the rest of the team may not have. This person can be within the organization or pulled from outside. They may have deep expertise in other areas, or they may be new and more likely to question everything. Innovation demands new ideas and ways of thinking. Adding a wildcard player to the team will help the creativity process.
BioPharma Drive: Drug Pricing
AUGUST 31, 2023
Two founding executives are leaving Sage alongside a major restructuring announced weeks after the FDA approved the medicine, Zurzuvae, for much narrower use than the company had hoped.
Drug Discovery World
AUGUST 8, 2023
The second quarter of 2023 has seen steady growth in financing activity for the UK’s life sciences sector, according to new data released by the BioIndustry Association (BIA) and Clarivate. The positive news comes soon after industry figures welcomed recent announcements to unlock new sources of capital in the City of London. Last month, the UK Chancellor and the Lord Mayor of London launched Mansion House Compact, which is an agreement by pension providers to allocate a minimum 5% to unlisted e
Drug Target Review
AUGUST 24, 2023
The focus of this study is on Growth Differentiation Factor-15 (GDF-15), a cytokine known for its critical role in feto-maternal tolerance, which has now been found to be hijacked by tumours to evade immune attack. We will explore how GDF-15 impacts the tumour microenvironment and hinders the infiltration of T cells into the tumour, as well as the implications of neutralising GDF-15 to reverse its inhibitory effects and sensitise tumours to anti-PD-1 treatment.
Drugs.com
AUGUST 31, 2023
THURSDAY, Aug. 31, 2023 -- When factoring in why children get asthma, a child's neighborhood may be important to consider. New research finds that living in a neighborhood during early childhood that has better access to resources was associated.
Drug Patent Watch
AUGUST 21, 2023
Loss of exclusivity (LOE) doesn’t have to spell doom for branded drug revenue streams. In the face of impending patent expirations, pharmaceutical companies can adopt key approaches to preserve meaningful… The post Strategies to Maximize Product Value Amid Loss of Exclusivity in the Pharmaceutical Industry appeared first on DrugPatentWatch - Make Better Decisions.
Perficient: Drug Development
AUGUST 24, 2023
The transition from a wholesale-centric business model to include a new direct-to-consumer (D2C) approach presents lucrative opportunities alongside a suite of technical and operational intricacies to consider. While the move brings manufacturing companies closer to end consumers, it also requires several considerations spanning content creation, post-purchase support, and overall brand experience.
BioPharma Drive: Drug Pricing
AUGUST 23, 2023
The company doesn’t know if the needles have caused retinal vasculitis in some people receiving its geographic atrophy drug Syfovre, but is no longer recommending their use.
Drug Discovery World
AUGUST 8, 2023
Astex Pharmaceuticals and MSD (Merck & Co) have announced an exclusive worldwide research collaboration to identify small molecule candidates with activity towards a tumour suppressor protein for the treatment of cancer. Under the terms of the agreement, Astex will apply its fragment-based drug discovery platform to develop compounds targeting multiple forms of the p53 tumour suppressor protein and provide MSD with lead compounds for further optimisation and preclinical development.
Broad Institute
AUGUST 17, 2023
#WhyIScience Q&A: A computational biologist helps build datasets for genetic disease diagnosis By Corie Lok August 17, 2023 Breadcrumb Home #WhyIScience Q&A: A computational biologist helps build datasets for genetic disease diagnosis Katherine Chao talks about her work managing the Genome Aggregation Database (gnomAD) and the importance of diverse datasets in rare disease diagnosis.
Drugs.com
AUGUST 28, 2023
MONDAY, Aug. 28, 2023 -- About half of older adults (52 percent) have heard of the new vaccines against respiratory syncytial virus (RSV), Arexvy and Abrysvo, according to the National Poll on Healthy Aging released online on Aug. 22.
SCIENMAG: Medicine & Health
AUGUST 17, 2023
Julie Carrier, professor and head of the University of Tennessee Department of Biosystems Engineering and Soil Science, was awarded the James R. and Karen A. Gilley Academic Leadership Award during the annual international meeting of the American Society of Agricultural and Biological Engineers (ASABE) in July.
Drug Patent Watch
AUGUST 16, 2023
Annual Drug Patent Expirations for REMODULIN Remodulin is a drug marketed by United Therap and is included in two NDAs. It is available from one supplier. There are nine patents… The post New patent for United Therap drug REMODULIN appeared first on DrugPatentWatch - Make Better Decisions.
BioPharma Drive: Drug Pricing
AUGUST 22, 2023
Billing itself as both a scientific and investment partner, Foundery aims to provide research grants and drug development support to researchers developing new immunotherapies.
Drug Discovery World
AUGUST 1, 2023
Researchers from the University of Liverpool, UK, have created a biomedical compound that has the potential to stop the spread of breast cancer. Scientists from the Chemistry and Biochemistry Departments at the University of Liverpool and Nanjing Medical School in China have discovered a possible way to block proteins that cause metastasis. The major problem hindering the successful treatment of commonly occurring cancers is not the primary tumour which can usually be removed by surgery, but its
Antidote
AUGUST 16, 2023
Primary sclerosing cholangitis (PSC) is a condition that impacts the bile ducts of the liver, causing them to become inflamed and ultimately scar. It primarily affects young and middle-aged men, and 80% of patients with PBC also have inflammatory bowel disease (IBD).
Drugs.com
AUGUST 31, 2023
THURSDAY, Aug. 31, 2023 -- If a loved one were living with addiction, a majority of Americans say they would know how to get help. About 71% of 2,200 respondents to an American Psychiatric Association poll said they would know how to assist a friend.
National Institute on Drug Abuse: Nora's Blog
AUGUST 14, 2023
Innovative projects answer NIDA’s challenge to implement substance use prevention in primary care astewart Mon, 08/14/2023 - 10:04 Nora's Blog August 22, 2023 Image ©Getty Images/ Maskot With nearly 110,000 people dying from drug overdoses last year, the crisis has not abated. We have effective treatments for opioid and other drug use disorders, but growing numbers of people are dying from fentanyl even in the absence of a substance use disorder—for instance, young people overdosing on fentanyl-
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