January, 2024

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CAR-T for lupus: the ‘tip of the iceberg’ for cell therapy in autoimmune disease

BioPharma Drive: Drug Pricing

Since a landmark paper in 2022, drugmakers have begun nearly a dozen trials of cell therapies for lupus, with more set to start. Here’s why their efforts are worth watching.

Therapies 352
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ADHD Drug Zenzedi Recalled Over Pill Mixup

Drugs.com

TUESDAY, Jan. 30, 2024 -- The maker of a drug used to treat ADHD and narcolepsy has recalled one lot of the medication after a pill mixup was discovered.The recall notice, issued by Azurity Pharmaceuticals Inc., states that one lot of Zenzedi.

Drugs 347
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Unprecedented ocean heating shows risks of a world 3°C warmer

Science Daily: Pharmacology News

New research examines the causes of the record-breaking ocean temperatures witnessed in 2023.

Research 363
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CDD Vault Update (January 2024)

Collaborative Drug

Import File Parser We're excited to announce a significant update to the CDD Vault Import Data wizard. This update introduces a flexible parser to accommodate a wider range of data file formats beyond the traditional tabular ("long and skinny") layout. Now, you can easily import data files organized in various formats, including those resembling a Plate layout.

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Bridging Innovation & Patient Care: The Growing Role of AI

Speaker: Simran Kaur, Co-founder & CEO at Tattva.Health

AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!

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Evolution might stop humans from solving climate change

Science Daily: Pharmacology News

Human culture has evolved to allow humans to extract resources and helped us expand to dominate the biosphere. But the same evolutionary processes may counteract efforts to solve new global environmental threats like climate change, according to a new study. Tackling the climate crisis will require worldwide regulatory, technical and economic systems supported by strong global cooperation.

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More Trending

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Scientists identify how dietary restriction slows brain aging and increases lifespan

Science Daily: Pharmacology News

Restricting calories is known to improve health and increase lifespan, but much of how it does so remains a mystery, especially in regard to how it protects the brain. Scientists have now uncovered a role for a gene called OXR1 that is necessary for the lifespan extension seen with dietary restriction and is essential for healthy brain aging.

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COVID Can Threaten Sickle Cell Patients, But Too Few Are Vaccinated

Drugs.com

FRIDAY, Jan. 12, 2024 -- Sickle cell disease is one of many chronic health conditions that dramatically increases the risk of hospitalization and death in people infected by COVID-19.Unfortunately, folks with sickle cell disease are much less.

Vaccine 353
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Bottled water can contain hundreds of thousands of previously uncounted tiny plastic bits

Science Daily: Pharmacology News

In recent years, there has been rising concern that tiny particles known as microplastics are showing up basically everywhere on Earth, from polar ice to soil, drinking water and food. Formed when plastics break down into progressively smaller bits, these particles are being consumed by humans and other creatures, with unknown potential health and ecosystem effects.

Research 353
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Trees struggle to 'breathe' as climate warms

Science Daily: Pharmacology News

Trees are struggling to sequester heat-trapping carbon dioxide (CO2) in warmer, drier climates, meaning that they may no longer serve as a solution for offsetting humanity's carbon footprint as the planet continues to warm, according to a new study.

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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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A new startup from Feng Zhang and an ex-Illumina executive zeroes in on the epigenome

BioPharma Drive: Drug Pricing

Moonwalk Biosciences, the latest biotech cofounded by the gene editing scientist, joins other startups aiming to alter gene expression without changing DNA.

DNA 349
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Self-powered sensor automatically harvests magnetic energy

Science Daily: Pharmacology News

Researchers have designed a self-powering, battery-free, energy-harvesting sensor. Using the framework they developed, they produced a temperature sensor that can harvest and store the energy from the magnetic field that exists in the open air around a wire.

Research 342
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A 'Universal' COVID Vaccine Could Save Billions If Another Pandemic Strikes

Drugs.com

FRIDAY, Jan. 12, 2024 -- A universal coronavirus vaccine could have saved millions of lives and billions of dollars if one had been available prior to the pandemic, a new study argues. Further, a universal vaccine -- one that targets parts of the.

Vaccine 342
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Scientists design a two-legged robot powered by muscle tissue

Science Daily: Pharmacology News

Compared to robots, human bodies are flexible, capable of fine movements, and can convert energy efficiently into movement. Drawing inspiration from human gait, researchers from Japan crafted a two-legged biohybrid robot by combining muscle tissues and artificial materials. This method allows the robot to walk and pivot.

Research 340
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How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

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Non-opioid drug from Vertex cuts pain in major trial tests

BioPharma Drive: Drug Pricing

The company plans to soon ask the FDA for approval of the drug, which it has pitched as a safer alternative to addictive opioid painkillers.

Trials 333
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Human beliefs about drugs could have dose-dependent effects on the brain

Science Daily: Pharmacology News

Mount Sinai researchers have shown for the first time that a person's beliefs related to drugs can influence their own brain activity and behavioral responses in a way comparable to the dose-dependent effects of pharmacology.

Drugs 332
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Ants recognize infected wounds and treat them with antibiotics

Science Daily: Pharmacology News

The African Matabele ants are often injured in fights with termites. Their conspecifics recognize when the wounds become infected and initiate antibiotic treatment.

Treatment 330
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Achieving sustainable urban growth on a global scale

Science Daily: Pharmacology News

An international group of leading scientists call for an urgent change in the governance of urban expansion as the world's cities continue to grow at unprecedented rates.

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Deliver Fast, Flexible Clinical Trial Insights with Spotfire

Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

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A long-lasting neural probe

Science Daily: Pharmacology News

An interdisciplinary team of researchers has developed a soft implantable device with dozens of sensors that can record single-neuron activity in the brain stably for months.

Research 325
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'Feel good' hormone could explain why exercise helps boost your brain

Science Daily: Pharmacology News

A study exploring the mechanisms behind why cognitive performance improves in response to exercise, has found that dopamine plays a key role.

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Study reveals function of little-understood synapse in the brain

Science Daily: Pharmacology News

New research for the first time reveals the function of a little-understood junction between cells in the brain that could have important treatment implications for conditions ranging from multiple sclerosis to Alzheimer's disease, to a type of brain cancer known as glioma. Neuroscientists focused on the synapse connecting neurons to a non-neuronal cell, known as oligodendrocyte precursor cells.

Treatment 324
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Study Links Use of Acetaminophen in Pregnancy With Child Behavioral Issues

Drugs.com

THURSDAY, Jan. 18, 2024 -- Expecting moms who often turn to acetaminophen for their aches and pains are more likely to wind up with kids who have behavioral issues, a new study warns.Children between the ages of 2 and 4 were more likely to have.

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Clinical Data Like You´ve Never Seen It Before: Why Spotfire Is the Leading Tool for Clinical Analytics

Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

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Solid state battery design charges in minutes, lasts for thousands of cycles

Science Daily: Pharmacology News

Researchers have developed a new lithium metal battery that can be charged and discharged at least 6,000 times -- more than any other pouch battery cell -- and can be recharged in a matter of minutes. The research not only describes a new way to make solid state batteries with a lithium metal anode but also offers new understanding into the materials used for these potentially revolutionary batteries.

Research 321
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'Giant' predator worms more than half a billion years old discovered in North Greenland

Science Daily: Pharmacology News

Fossils of a new group of animal predators have been located in the Early Cambrian Sirius Passet fossil locality in North Greenland. These large worms may be some of the earliest carnivorous animals to have colonized the water column more than 518 million years ago, revealing a past dynasty of predators that scientists didn't know existed.

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Catalytic combo converts CO2 to solid carbon nanofibers

Science Daily: Pharmacology News

Scientists have developed a way to convert carbon dioxide (CO2), a potent greenhouse gas, into carbon nanofibers, materials with a wide range of unique properties and many potential long-term uses. Their strategy uses tandem electrochemical and thermochemical reactions run at relatively low temperatures and ambient pressure and could successfully lock carbon away to offset or even achieve negative carbon emissions.

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Researchers rely on Earth's magnetic field to verify an event mentioned in the Old Testament

Science Daily: Pharmacology News

A new study scientifically corroborates an event described in the Second Book of Kings -- the conquest of the Philistine city of Gath by Hazael King of Aram. The method is based on measuring the magnetic field recorded in burnt bricks. The researchers say that the findings are important for determining the intensity of the fire and the scope of destruction in Gath, and also for understanding construction practices in the region.

Research 318
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Study suggests secret for getting teens to listen to unsolicited advice

Science Daily: Pharmacology News

A new study may hold a secret for getting your teenager to listen to appreciate your unsolicited advice. The study, which included 'emerging adults' -- those in their late teens and early 20s -- found teens will appreciate parents' unsolicited advice, but only if the parent is supportive of their teens' autonomy.

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