December, 2023

article thumbnail

AI's memory-forming mechanism found to be strikingly similar to that of the brain

Science Daily: Pharmacology News

An interdisciplinary team consisting of researchers has revealed a striking similarity between the memory processing of artificial intelligence (AI) models and the hippocampus of the human brain. This new finding provides a novel perspective on memory consolidation, which is a process that transforms short-term memories into long-term ones, in AI systems.

Research 357
article thumbnail

‘No tolerance for failure’: An oral history of the first CRISPR medicine

BioPharma Drive: Drug Pricing

A new sickle cell disease therapy developed by CRISPR Therapeutics and Vertex Pharmaceuticals is now approved in the U.S. and U.K. This is the story of how it came to be.

Therapies 356
Insiders

Sign Up for our Newsletter

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

article thumbnail

Common Stomach Bug Is Linked to Higher Alzheimer's Risk

Drugs.com

THURSDAY, Dec. 28, 2023 -- A common stomach bug may play a part in Alzheimer's disease risk.New research found that older folks infected with Helicobacter pylori (H. pylori) had greater odds for developing Alzheimer's, the most common type of.

Disease 329
article thumbnail

Drug Discovery Industry Roundup with Barry Bunin — December 18, 2023

Collaborative Drug

Discover the impact of 'junk DNA' on cancer, teen obesity treatments, Neanderthal genes on sleep patterns, and Nobel discoveries shaping medicine

DNA 298
article thumbnail

Bridging Innovation & Patient Care: The Growing Role of AI

Speaker: Simran Kaur, Co-founder & CEO at Tattva.Health

AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!

article thumbnail

The Inflation Reduction Act Is Not Impacting Pharma R&D – Yet

Forbes: Drug Truths

Entitled "Pharmaceutical innovation and the Inflation Reduction Act: What can we learn from the first half of 2023", this policy brief examines whether "the IRA has ha.

More Trending

article thumbnail

CRISPR therapy for sickle cell approved by FDA in gene editing milestone

BioPharma Drive: Drug Pricing

In addition to clearing Vertex Pharmaceuticals and CRISPR Therapeutics’ Casgevy, the FDA also granted an early OK to Bluebird bio’s sickle cell treatment Lyfgenia.

FDA 347
article thumbnail

More than a meteorite: New clues about the demise of dinosaurs

Science Daily: Pharmacology News

What wiped out the dinosaurs? A meteorite plummeting to Earth is only part of the story, a new study suggests. Climate change triggered by massive volcanic eruptions may have ultimately set the stage for the dinosaur extinction, challenging the traditional narrative that a meteorite alone delivered the final blow to the ancient giants.

337
337
article thumbnail

New protein linked to early-onset dementia identified

Science Daily: Pharmacology News

Scientists have identified abnormal aggregates of a protein called TAF15 in the brains of individuals with early-onset dementia, known as frontotemporal dementia, where the cause was not previously known.

334
334
article thumbnail

How technology and economics can help save endangered species

Science Daily: Pharmacology News

A lot has changed in the world since the Endangered Species Act (ESA) was enacted 50 years ago in December 1973. Experts are now discuss how the ESA has evolved and what its future might hold.

330
330
article thumbnail

From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

article thumbnail

Harvesting water from air with solar power

Science Daily: Pharmacology News

Researchers have developed a promising new solar-powered atmospheric water harvesting technology that could help provide enough drinking water for people to survive in difficult, dryland areas: They synthesized a super hygroscopic gel capable of absorbing and retaining an unparalleled amount of water. One kilogram of dry gel could adsorb 1.18 kilograms of water in arid atmospheric environments and up to 6.4 kilograms in humid atmospheric environments.

Research 330
article thumbnail

Stimulating nerves connected to the pancreas regenerates insulin-producing cells, mouse study shows

Science Daily: Pharmacology News

Decreasing pancreatic beta cell numbers -- the only cells that produce insulin -- is a leading cause of diabetes. In a promising development, a research group has revealed that stimulating autonomic vagal nerves connected to the pancreas can improve the function and also increase the number of pancreatic beta cells in mice.

Research 328
article thumbnail

Can we decode the language of our primate cousins?

Science Daily: Pharmacology News

Are we able to differentiate between the vocal emissions of certain primates? A team asked volunteers to categorize the vocalizations of three species of great apes (Hominidae) and humans. During each exposure to these ''onomatopoeia'', brain activity was measured. Unlike previous studies, the scientists reveal that phylogenetic proximity -- or kinship -- is not the only factor influencing our ability to identify these sounds.

324
324
article thumbnail

How a drought led to the rise of skateboarding in 1970s California

Science Daily: Pharmacology News

Why did professional skateboarding arise in southern California in the 1970s? Was it a coincidence, or was it a perfect storm of multiple factors? It's fairly well-known that a drought in southern California in the mid-1970s led to a ban on filling backyard swimming pools, and these empty pools became playgrounds for freestyle skateboarders in the greater Los Angeles area.

324
324
article thumbnail

How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

article thumbnail

Human behavior guided by fast changes in dopamine levels

Science Daily: Pharmacology News

A new study shows that dopamine release in the human brain plays a crucial role in encoding both reward and punishment prediction errors. This means that dopamine is involved in the process of learning from both positive and negative experiences, allowing the brain to adjust and adapt its behavior based on the outcomes of these experiences.

324
324
article thumbnail

Snail-inspired robot could scoop ocean microplastics

Science Daily: Pharmacology News

Inspired by a small and slow snail, scientists have developed a robot protype that may one day scoop up microplastics from the surfaces of oceans, seas and lakes.

324
324
article thumbnail

Tome Biosciences debuts with $213M and a new way to edit the genome

BioPharma Drive: Drug Pricing

Based on the work of MIT scientists, the well-funded startup is developing ways to insert large sizes of genetic material anywhere in the genome without damaging or breaking DNA.

DNA 323
article thumbnail

Radiopharma startup Artbio raises $90M in sign of field’s momentum

BioPharma Drive: Drug Pricing

The funding is indicative of investor interest in an area of drug research that involves at least a dozen startups and multiple publicly traded companies.

article thumbnail

Deliver Fast, Flexible Clinical Trial Insights with Spotfire

Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

article thumbnail

Researchers study a million galaxies to find out how the universe began

Science Daily: Pharmacology News

Researchers have analyzed more than one million galaxies to explore primordial fluctuations that seeded the formation of the structure of the entire universe.

Research 321
article thumbnail

Exoplanets'climate -- it takes nothing to switch from habitable to hell

Science Daily: Pharmacology News

The Earth is a wonderful blue and green dot covered with oceans and life, while Venus is a yellowish sterile sphere that is not only inhospitable but also sterile. However, the difference between the two bears to only a few degrees in temperature. A team of astronomers has achieved a world's first by managing to simulate the entirety of the runaway greenhouse process which can transform the climate of a planet from idyllic and perfect for life, to a place more than harsh and hostile.

321
321
article thumbnail

Rheumatoid Arthritis Drug, Baricitinib (Olumiant), Could Put Brakes on Type 1 Diabetes

Drugs.com

THURSDAY, Dec. 7, 2023 -- A drug long used to curb rheumatoid arthritis may be a potent foe against another immune disorder, type 1 diabetes. Australian researchers report that baricitinib (Olumiant) appears to help patients newly diagnosed with.

Drugs 321
article thumbnail

What happens in the brain while daydreaming?

Science Daily: Pharmacology News

During quiet waking, brain activity in mice suggests the animals are daydreaming about a recent image. Having daydreams about a recently viewed image predicted how the brain would respond to the image in the future. The findings provide a clue that daydreams may play a role in brain plasticity.

321
321
article thumbnail

Clinical Data Like You´ve Never Seen It Before: Why Spotfire Is the Leading Tool for Clinical Analytics

Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

article thumbnail

Scientists unveil complete cell map of a whole mammalian brain

Science Daily: Pharmacology News

Researchers have created a complete cell atlas of a whole mammalian brain. This atlas serves as a map for the mouse brain, describing the type, location, and molecular information of more than 32 million cells and providing information on connectivity between these cells.

Research 320
article thumbnail

ChatGPT often won't defend its answers -- even when it is right

Science Daily: Pharmacology News

ChatGPT may do an impressive job at correctly answering complex questions, but a new study suggests it may be absurdly easy to convince the AI chatbot that it's in the wrong.

321
321
article thumbnail

Fossil CO2 emissions at record high in 2023

Science Daily: Pharmacology News

Global carbon emissions from fossil fuels have risen again in 2023 -- reaching record levels, according to new research.

Research 321
article thumbnail

One of the largest magnetic storms in history quantified: Aurorae covered much of the night sky from the Tropics to the Polar Regions

Science Daily: Pharmacology News

An international multidisciplinary team consisting of solar physicists, geophysicists, and historians from nine countries analysed observations of an extreme solar-terrestrial storm reported in historical records from February 1872. Their findings confirm that a moderate sunspot group triggered one of the largest magnetic storms ever recorded, almost covering the entire night sky with colourful aurorae in both hemispheres.

article thumbnail

How jellyfish regenerate functional tentacles in days

Science Daily: Pharmacology News

At about the size of a pinkie nail, the jellyfish species Cladonema can regenerate an amputated tentacle in two to three days -- but how? Regenerating functional tissue across species, including salamanders and insects, relies on the ability to form a blastema, a clump of undifferentiated cells that can repair damage and grow into the missing appendage.

318
318