Early Impact Of The Inflation Reduction Act On Drug Discovery
Forbes: Drug Truths
MARCH 6, 2024
There is another aspect of this provision of the IRA that is starting to be felt – "the small molecule penalty"
March, 2024
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FDA Warns of Toxic Lead in Cinnamon Products
Drugs.com
MARCH 6, 2024
WEDNESDAY, March 6, 2024 -- The U.S. Food and Drug Administration issued a health advisory Wednesday warning consumers that six brands of ground cinnamon are tainted with lead. The FDA urged folks to throw away and not buy the following brands of.
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8-hour time-restricted eating linked to a 91% higher risk of cardiovascular death
Science Daily: Pharmacology News
MARCH 20, 2024
A study of over 20,000 adults found that those who followed an 8-hour time-restricted eating schedule, a type of intermittent fasting, had a 91% higher risk of death from cardiovascular disease.
Scientists generate new targeted protein degradation system that tunes a cell’s own proteins
Broad Institute
MARCH 14, 2024
Scientists generate new targeted protein degradation system that tunes a cell’s own proteins By Leah Eisenstadt March 14, 2024 Breadcrumb Home Scientists generate new targeted protein degradation system that tunes a cell’s own proteins Researchers have engineered a compact degron tag that can be precisely edited into a cell’s genome, enabling scientists to trigger the rapid breakdown of native target proteins.
From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience
Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.
The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven
Amylyx ALS drug fails crucial study, putting company’s future in doubt
BioPharma Drive: Drug Pricing
MARCH 8, 2024
The results have led Amylyx to pause promotion of Relyvrio and potentially pull it from the market in the coming weeks, a major blow to the company and ALS patients.
Unlocking the potential of natural products in drug discovery
Drug Target Review
MARCH 28, 2024
Between 2000 and 2020, approximately 30 percent of the newly introduced small molecule drugs were derived from natural products. 1 Surprisingly, however, less than one percent of the natural world’s chemical composition has been identified or studied by scientists. While plant-derived molecules (phytochemicals) have long played an essential role in drug discovery due to their diverse biological activities and chemical properties, the reliance on time-consuming and expensive screening techniques
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U.S. Mpox Cases Rising Again as Vaccinations Lag
Drugs.com
MARCH 28, 2024
THURSDAY, March 28, 2024 -- Mpox cases are climbing again in the United States, with the number of reported infections now twice as high as they were at this time last year, new government data shows.In response, public health experts have raised.
Two artificial intelligences talk to each other
Science Daily: Pharmacology News
MARCH 18, 2024
Performing a new task based solely on verbal or written instructions, and then describing it to others so that they can reproduce it, is a cornerstone of human communication that still resists artificial intelligence (AI). A team has succeeded in modelling an artificial neural network capable of this cognitive prowess. After learning and performing a series of basic tasks, this AI was able to provide a linguistic description of them to a 'sister' AI, which in turn performed them.
Messenger RNAs with multiple “tails” could lead to more effective therapeutics
Broad Institute
MARCH 22, 2024
Messenger RNAs with multiple “tails” could lead to more effective therapeutics By Corie Lok March 22, 2024 Breadcrumb Home Messenger RNAs with multiple “tails” could lead to more effective therapeutics Scientists have engineered long lasting mRNAs that increased therapeutic protein production in cells and animals. By Kat J. McAlpine March 22, 2024 Credit: Catherine Boush, Broad Communications Related news New method tracks gene expression in single cells over space and time Messenger RNA (mRNA)
Madrigal wins FDA approval of first drug for MASH
BioPharma Drive: Drug Pricing
MARCH 14, 2024
Rezdiffra’s clearance is a turning point in the fight against the liver disease. But its sales potential is unclear, and competition could emerge from popular weight loss drugs.
How Machine Learning Drives Clinical Trial Efficiency
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Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.
What do volunteers for research studies do after finding a trial?
Antidote
MARCH 12, 2024
For many people, participating in a research study presents an interesting opportunity with many benefits to volunteering. While there are many types of clinical research, all with distinct goals and timelines, trial volunteers will follow a similar path when taking part. Read on to learn more about the process.
#ScienceSaturday: March 2, 2024
KIF1A
MARCH 2, 2024
#ScienceSaturday posts share exciting scientific developments and educational resources with the KAND community. Each week, Dr. Dylan Verden of KIF1A.ORG summarizes newly published KIF1A-related research and highlights progress in rare disease research and therapeutic development. KIF1A-Related Research SPARKing New Insight Into Autism Across the Lifespan When I was growing up, autism was still unfamiliar to many; people may had heard the term but families often had to educate themselves, their
Measles Outbreaks Have CDC Tweaking Travel Guidelines
Drugs.com
MARCH 18, 2024
MONDAY, March 18, 2024 -- As millions of Americans prepare to travel abroad this summer and measles outbreaks increase worldwide, the U.S. Centers for Disease Control and Prevention has tightened its guidance on how travelers should handle the.
James Webb Space Telescope captures the end of planet formation
Science Daily: Pharmacology News
MARCH 22, 2024
How much time do planets have to form from a swirling disk of gas and dust around a star? A new study gives scientists a better idea of how our own solar system came to be.
Deliver Fast, Flexible Clinical Trial Insights with Spotfire
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Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.
Researchers roll out a more accurate way to estimate genetic risks of disease
Broad Institute
MARCH 19, 2024
Researchers roll out a more accurate way to estimate genetic risks of disease By Claire Hendershot March 19, 2024 Breadcrumb Home Researchers roll out a more accurate way to estimate genetic risks of disease Two new approaches for generating polygenic scores demonstrate that compiled data improves score accuracy. By Claire Hendershot March 19, 2024 Image by Ricardo Job-Reese, Broad Communications.
Biotech stock fundings headed for best quarter in 3 years, Jefferies says
BioPharma Drive: Drug Pricing
MARCH 11, 2024
Publicly traded companies raised nearly $10 billion in follow-on stock offerings in January and February, a financing surge that’s driving a “sector recovery,” the investment bank said.
Vector Space Biosciences: Leading Innovation in Space Medicine with AI
DrugBank
MARCH 28, 2024
Space biosciences are on the verge of becoming one of the largest total addressable markets to ever exist, opening up vast opportunities for economic growth and scientific discovery. In the realm of space exploration, one critical yet often overlooked aspect is the impact of space conditions on human health. The goal of sending humans to space for increasingly longer periods of time is contingent on our ability to ensure astronauts' health.
Antidote anecdotes: A conversation with an MS care partner
Antidote
MARCH 27, 2024
MS is a chronic disease that is estimated to impact over a million Americans. The condition causes damage to the body’s central nervous system, leading to numbness, memory problems, sight issues, and difficulties with coordination.
Clinical Data Like You´ve Never Seen It Before: Why Spotfire Is the Leading Tool for Clinical Analytics
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Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic
Carcinogen Benzene Can Form in Some Acne Treatments: Report
Drugs.com
MARCH 7, 2024
THURSDAY, March 7, 2024 -- Some acne treatments may may banish blemishes but carry hidden dangers: A new report reveals high levels of the carcinogen benzene can form in products that contain the zit-fighting ingredient benzoyl peroxide.According.
AI outperforms humans in standardized tests of creative potential
Science Daily: Pharmacology News
MARCH 1, 2024
In a recent study, 151 human participants were pitted against ChatGPT-4 in three tests designed to measure divergent thinking, which is considered to be an indicator of creative thought.
Schizophrenia and aging may share a common biological basis
Broad Institute
MARCH 6, 2024
Schizophrenia and aging may share a common biological basis By Allessandra DiCorato March 6, 2024 Breadcrumb Home Schizophrenia and aging may share a common biological basis Tightly synchronized genetic changes in two types of brain cells may underlie cognitive impairment in both conditions, offering potential therapeutic clues. By Allessandra DiCorato March 6, 2024 Credit: Ricardo Job-Reese, Broad Communications A new study of aging and schizophrenia reveals synchronized gene expression in astr
Madrigal, FDA approval in hand, outlines plan to sell MASH drug
BioPharma Drive: Drug Pricing
MARCH 15, 2024
The company expects initial uptake of Rezdiffra, which costs $47,400 per year, to be slow as doctors and insurers establish the protocols needed to find patients eligible for treatment.
It’s Time To Update Your Data Lake Ingestion Strategy
Perficient: Drug Development
MARCH 5, 2024
If you built your data lake in the last 5-7 years, you probably are ingesting data into the data lake using many batch jobs that ingest and update data in the data lake. There is nothing wrong with what you did, but data technology has continued to move forward and in my opinion, the time has come to change your data lake ingestion strategy to reduce the number of high-latency batch jobs and move toward primarily using real-time change data capture (CDC).
7 things to know about multiple sclerosis
Antidote
MARCH 14, 2024
Receiving a multiple sclerosis (MS) diagnosis can feel overwhelming and isolating for many. MS is a neurodegenerative disease that often involves challenging symptoms — but knowing what to expect and what resources are available can help.
High-Strength Lidocaine Skin Creams Can Cause Seizures, Heart Trouble, FDA Warns
Drugs.com
MARCH 29, 2024
FRIDAY, March 29, 2024 -- Some pain-relieving skin products contain potentially harmful doses of the numbing agent lidocaine and should be avoided, the U.S. Food and Drug Administration warns.These creams, gels, sprays and soaps are marketed for.
Risk factors for faster aging in the brain revealed in new study
Science Daily: Pharmacology News
MARCH 27, 2024
Researchers have used data from UK Biobank participants to reveal that diabetes, traffic-related air pollution and alcohol intake are the most harmful out of 15 modifiable risk factors for dementia.
Spatial study of lung cancer reveals immune markers of response to immunotherapy
Broad Institute
MARCH 20, 2024
Spatial study of lung cancer reveals immune markers of response to immunotherapy By Corie Lok March 20, 2024 Breadcrumb Home Spatial study of lung cancer reveals immune markers of response to immunotherapy Researchers visualize how immune cells are spatially organized within tumors and show that certain immune “hubs” are linked to better treatment responses.
After surprise trial failure, ALS doctors brace for one less treatment option
BioPharma Drive: Drug Pricing
MARCH 12, 2024
Physicians are preparing for tough conversations with patients on Amylyx Pharmaceuticals’ drug, Relyvrio, while holding out hope it still may help some with the disease.
Perficient Included in Forrester’s The Adobe Services Landscape
Perficient: Drug Development
MARCH 1, 2024
In a dynamic digital landscape, choosing the right provider among the Adobe services landscape is paramount for businesses seeking to maximize their Adobe investments. The selection process can be daunting with a diverse set of providers that vary by size, type of offering, geography, and business scenario differentiation. So where do marketing leaders start?
Women in Stem with Katherine Tran
Drug Target Review
MARCH 13, 2024
Can you tell us about your journey in the field of STEM and the challenges you encountered along the way? To be honest, this is something I have never taken the time to reflect on until now. At first thought, I would say my journey in the field of STEM has been an exciting and rewarding experience. However, when I get to really think back on my journey throughout STEM, it has honestly been quite a rollercoaster ride with many bumps along the way.
CDC Warns of Spike in Bacterial Illness That Can Cause Meningitis
Drugs.com
MARCH 29, 2024
FRIDAY, March 29, 2024 -- There has been a troubling rise in cases of a rare bacterial illness that can cause meningitis, U.S. health officials warned Thursday.In an alert issued to doctors, the U.S. Centers for Disease Control and Prevention said.
Breathe, don't vent: Turning down the heat is key to managing anger
Science Daily: Pharmacology News
MARCH 18, 2024
Venting about a source of anger might feel good in the moment, but it's not effective at reducing the rage, new research suggests. Instead, techniques often used to address stress -- deep breathing, mindfulness, meditation, yoga or even counting to 10 -- have been shown to be more effective at decreasing anger and aggression.
Study reveals genetic clusters that may explain differences in type 2 diabetes risk
Broad Institute
MARCH 8, 2024
Study reveals genetic clusters that may explain differences in type 2 diabetes risk By Corie Lok March 8, 2024 Breadcrumb Home Study reveals genetic clusters that may explain differences in type 2 diabetes risk The clusters point to a range of biological processes that likely contribute to the development of type 2 diabetes. By Brandon Chase, Massachusetts General Hospital Communications March 8, 2024 Related content Largest and most diverse genome-wide association study of type 2 diabetes revea
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