Forbes: Drug Truths

MARCH 6, 2024

There is another aspect of this provision of the IRA that is starting to be felt – "the small molecule penalty"

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Drugs.com

MARCH 6, 2024

WEDNESDAY, March 6, 2024 -- The U.S. Food and Drug Administration issued a health advisory Wednesday warning consumers that six brands of ground cinnamon are tainted with lead. The FDA urged folks to throw away and not buy the following brands of.

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Science Daily: Pharmacology News

MARCH 20, 2024

A study of over 20,000 adults found that those who followed an 8-hour time-restricted eating schedule, a type of intermittent fasting, had a 91% higher risk of death from cardiovascular disease.

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Disease 143

Broad Institute

MARCH 14, 2024

Scientists generate new targeted protein degradation system that tunes a cell’s own proteins By Leah Eisenstadt March 14, 2024 Breadcrumb Home Scientists generate new targeted protein degradation system that tunes a cell’s own proteins Researchers have engineered a compact degron tag that can be precisely edited into a cell’s genome, enabling scientists to trigger the rapid breakdown of native target proteins.

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Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

Treatment

BioPharma Drive: Drug Pricing

MARCH 8, 2024

The results have led Amylyx to pause promotion of Relyvrio and potentially pull it from the market in the coming weeks, a major blow to the company and ALS patients.

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Drug Target Review

MARCH 28, 2024

Between 2000 and 2020, approximately 30 percent of the newly introduced small molecule drugs were derived from natural products. 1 Surprisingly, however, less than one percent of the natural world’s chemical composition has been identified or studied by scientists. While plant-derived molecules (phytochemicals) have long played an essential role in drug discovery due to their diverse biological activities and chemical properties, the reliance on time-consuming and expensive screening techniques

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Drugs.com

MARCH 28, 2024

THURSDAY, March 28, 2024 -- Mpox cases are climbing again in the United States, with the number of reported infections now twice as high as they were at this time last year, new government data shows.In response, public health experts have raised.

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Science Daily: Pharmacology News

MARCH 27, 2024

What would you do if you walked up to a robot with a human-like head and it smiled at you first? You'd likely smile back and perhaps feel the two of you were genuinely interacting. But how does a robot know how to do this? Or a better question, how does it know to get you to smile back?

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Broad Institute

MARCH 22, 2024

Messenger RNAs with multiple “tails” could lead to more effective therapeutics By Corie Lok March 22, 2024 Breadcrumb Home Messenger RNAs with multiple “tails” could lead to more effective therapeutics Scientists have engineered long lasting mRNAs that increased therapeutic protein production in cells and animals. By Kat J. McAlpine March 22, 2024 Credit: Catherine Boush, Broad Communications Related news New method tracks gene expression in single cells over space and time Messenger RNA (mRNA)

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BioPharma Drive: Drug Pricing

MARCH 14, 2024

Rezdiffra’s clearance is a turning point in the fight against the liver disease. But its sales potential is unclear, and competition could emerge from popular weight loss drugs.

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Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

Clinical Trials

Perficient: Drug Development

MARCH 6, 2024

In December 2022, the Department of Health and Human Services released a bulletin announcing additional compliance requirements for healthcare marketers when it comes to third-party trackers. The guidance lays forth expectations for how healthcare organizations collect data on activities that take place on their website and mobile apps. So, what’s the problem?

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Marketing Regulations Compliance Science 122

Antidote

MARCH 12, 2024

For many people, participating in a research study presents an interesting opportunity with many benefits to volunteering. While there are many types of clinical research, all with distinct goals and timelines, trial volunteers will follow a similar path when taking part. Read on to learn more about the process.

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Trials Research Clinical Research 119

Drugs.com

MARCH 18, 2024

MONDAY, March 18, 2024 -- As millions of Americans prepare to travel abroad this summer and measles outbreaks increase worldwide, the U.S. Centers for Disease Control and Prevention has tightened its guidance on how travelers should handle the.

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Disease 124

Science Daily: Pharmacology News

MARCH 25, 2024

A new study combining genetic, palaeoecological, and archaeological evidence has unveiled the Persian Plateau as a pivotal geographic location serving as a hub for Homo sapiens during the early stages of their migration out of Africa. It highlights the period between 70,000 to 45,000 years ago when human populations did not uniformly spread across Eurasia, leaving a gap in our understanding of their whereabouts during this time frame.

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Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

Clinical Trials

Broad Institute

MARCH 19, 2024

Researchers roll out a more accurate way to estimate genetic risks of disease By Claire Hendershot March 19, 2024 Breadcrumb Home Researchers roll out a more accurate way to estimate genetic risks of disease Two new approaches for generating polygenic scores demonstrate that compiled data improves score accuracy. By Claire Hendershot March 19, 2024 Image by Ricardo Job-Reese, Broad Communications.

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BioPharma Drive: Drug Pricing

MARCH 11, 2024

Publicly traded companies raised nearly $10 billion in follow-on stock offerings in January and February, a financing surge that’s driving a “sector recovery,” the investment bank said.

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KIF1A

MARCH 2, 2024

#ScienceSaturday posts share exciting scientific developments and educational resources with the KAND community. Each week, Dr. Dylan Verden of KIF1A.ORG summarizes newly published KIF1A-related research and highlights progress in rare disease research and therapeutic development. KIF1A-Related Research SPARKing New Insight Into Autism Across the Lifespan When I was growing up, autism was still unfamiliar to many; people may had heard the term but families often had to educate themselves, their

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Antidote

MARCH 27, 2024

MS is a chronic disease that is estimated to impact over a million Americans. The condition causes damage to the body’s central nervous system, leading to numbness, memory problems, sight issues, and difficulties with coordination.

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Disease 116

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Clinical Trials

Drugs.com

MARCH 7, 2024

THURSDAY, March 7, 2024 -- Some acne treatments may may banish blemishes but carry hidden dangers: A new report reveals high levels of the carcinogen benzene can form in products that contain the zit-fighting ingredient benzoyl peroxide.According.

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Science Daily: Pharmacology News

MARCH 18, 2024

Performing a new task based solely on verbal or written instructions, and then describing it to others so that they can reproduce it, is a cornerstone of human communication that still resists artificial intelligence (AI). A team has succeeded in modelling an artificial neural network capable of this cognitive prowess. After learning and performing a series of basic tasks, this AI was able to provide a linguistic description of them to a 'sister' AI, which in turn performed them.

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Broad Institute

MARCH 6, 2024

Schizophrenia and aging may share a common biological basis By Allessandra DiCorato March 6, 2024 Breadcrumb Home Schizophrenia and aging may share a common biological basis Tightly synchronized genetic changes in two types of brain cells may underlie cognitive impairment in both conditions, offering potential therapeutic clues. By Allessandra DiCorato March 6, 2024 Credit: Ricardo Job-Reese, Broad Communications A new study of aging and schizophrenia reveals synchronized gene expression in astr

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Medical Schools RNA Science Research 134

BioPharma Drive: Drug Pricing

MARCH 14, 2024

The funding for the startup, which partnered with Bristol Myers Squibb last year, adds to a surge of recent investments in developers of antibody-drug conjugates.

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Drugs 122

DrugBank

MARCH 28, 2024

Space biosciences are on the verge of becoming one of the largest total addressable markets to ever exist, opening up vast opportunities for economic growth and scientific discovery.  In the realm of space exploration, one critical yet often overlooked aspect is the impact of space conditions on human health. The goal of sending humans to space for increasingly longer periods of time is contingent on our ability to ensure astronauts' health.

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DNA Laboratories Disease Engineering 115

Antidote

MARCH 14, 2024

Receiving a multiple sclerosis (MS) diagnosis can feel overwhelming and isolating for many. MS is a neurodegenerative disease that often involves challenging symptoms — but knowing what to expect and what resources are available can help.

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Disease 116

Drugs.com

MARCH 29, 2024

FRIDAY, March 29, 2024 -- Some pain-relieving skin products contain potentially harmful doses of the numbing agent lidocaine and should be avoided, the U.S. Food and Drug Administration warns.These creams, gels, sprays and soaps are marketed for.

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Science Daily: Pharmacology News

MARCH 1, 2024

In a recent study, 151 human participants were pitted against ChatGPT-4 in three tests designed to measure divergent thinking, which is considered to be an indicator of creative thought.

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Broad Institute

MARCH 20, 2024

Spatial study of lung cancer reveals immune markers of response to immunotherapy By Corie Lok March 20, 2024 Breadcrumb Home Spatial study of lung cancer reveals immune markers of response to immunotherapy Researchers visualize how immune cells are spatially organized within tumors and show that certain immune “hubs” are linked to better treatment responses.

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BioPharma Drive: Drug Pricing

MARCH 15, 2024

The company expects initial uptake of Rezdiffra, which costs $47,400 per year, to be slow as doctors and insurers establish the protocols needed to find patients eligible for treatment.

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FDA Approval Doctors FDA Treatment 121

Perficient: Drug Development

MARCH 5, 2024

If you built your data lake in the last 5-7 years, you probably are ingesting data into the data lake using many batch jobs that ingest and update data in the data lake. There is nothing wrong with what you did, but data technology has continued to move forward and in my opinion, the time has come to change your data lake ingestion strategy to reduce the number of high-latency batch jobs and move toward primarily using real-time change data capture (CDC).

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Drug Discovery Today

MARCH 1, 2024

In July 2022 the SMR hosted a conference on ‘Innovative new pharma and biotech partnerships: How is the landscape transforming?’ That conference looked at ongoing developments in pharmaceutical discovery and development, focused on the need for partnerships between large pharmaceutical and new biotech companies to tackle the next generation therapeutic challenges.

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Pharmaceuticals 113

Drugs.com

MARCH 29, 2024

FRIDAY, March 29, 2024 -- There has been a troubling rise in cases of a rare bacterial illness that can cause meningitis, U.S. health officials warned Thursday.In an alert issued to doctors, the U.S. Centers for Disease Control and Prevention said.

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Science Daily: Pharmacology News

MARCH 20, 2024

A new study has shown that food-seeking cells exist in a part of a mouse's brain usually associated with panic -- but not with feeding. Activating a selective cluster of these cells kicked mice into 'hot pursuit' of live and non-prey food, and showed a craving for fatty foods intense enough that the mice endured foot shocks to get them, something full mice normally would not do.

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Broad Institute

MARCH 8, 2024

Study reveals genetic clusters that may explain differences in type 2 diabetes risk By Corie Lok March 8, 2024 Breadcrumb Home Study reveals genetic clusters that may explain differences in type 2 diabetes risk The clusters point to a range of biological processes that likely contribute to the development of type 2 diabetes. By Brandon Chase, Massachusetts General Hospital Communications March 8, 2024 Related content Largest and most diverse genome-wide association study of type 2 diabetes revea

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