Forbes: Drug Truths

NOVEMBER 8, 2023

Medicare will save money but there will be fewer new medicines.

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Science Daily: Pharmacology News

NOVEMBER 21, 2023

Recent research has shown that engravings in a cave in La Roche-Cotard (France), which has been sealed for thousands of years, were actually made by Neanderthals. The findings reveal that the Neanderthals were the first humans with an appreciation of art.

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Research 144

Broad Institute

NOVEMBER 23, 2023

Search algorithm reveals nearly 200 new kinds of CRISPR systems By Allessandra DiCorato November 23, 2023 Breadcrumb Home Search algorithm reveals nearly 200 new kinds of CRISPR systems By analyzing bacterial data, researchers have discovered thousands of rare new CRISPR systems that have a range of functions and could enable gene editing, diagnostics, and more.

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Drug Target Review

NOVEMBER 1, 2023

Autotaxin (ATX) is a 99-125 kDa lysophospholipase D involved in a large range of physiological and pathological processes. 1 This critical enzyme is part of the nucleotide pyrophosphatase/ phosphodiesterase family and is also referred to as ENPP2. Five ATX isoforms have been identified, with ATX-b expressed in most human tissues and ATX-g specific to the central nervous system.

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Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

Treatment

NIOSH Science Blog: Drugs

NOVEMBER 20, 2023

In May, the U.S. Surgeon General, Vice Admiral Vivek Murthy, MD, MBA, released Our Epidemic of Loneliness and Isolation: The U.S. Surgeon General’s Advisory on the Healing Effects of Social Connection and Community calling for a whole-of-society approach to address the epidemic of loneliness and isolation.1 Below we briefly highlight information from the Advisory and its implications for worker well-being.

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Research 133

BioPharma Drive: Drug Pricing

NOVEMBER 21, 2023

The partnership is another investment by the biotech subsidiary in artificial intelligence for drug discovery and development, continuing an industry trend.

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Drugs 131

Science Daily: Pharmacology News

NOVEMBER 27, 2023

The intensity and frequency of extreme rainfall increases exponentially with global warming, a new study finds. The analysis shows that state-of-the-art climate models significantly underestimate how much extreme rainfall increases under global warming -- meaning that extreme rainfall could increase quicker than climate models suggest.

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Drugs.com

NOVEMBER 3, 2023

THURSDAY, Nov. 2, 2023 -- A procedure to treat the irregular heart rhythm condition known as atrial fibrillation (a-fib) works just as well for women as it does for men, new research shows. The technology, called pulsed field ablation (PFA), can be.

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Therapies Research 130

Practical Cheminformatics

NOVEMBER 27, 2023

In my last post , I discussed benchmark datasets for machine learning (ML) in drug discovery and several flaws in widely used datasets. In this installment, I’d like to focus on how methods are compared. Every year, dozens, if not hundreds, of papers present comparisons of ML methods or molecular representations. These papers typically conclude that one approach is superior to several others for a specific task.

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Packaging Drugs 128

Antidote

NOVEMBER 9, 2023

Before any new treatment or therapy is able to be used by the patient population, it must go through the process of a clinical trial — this is the case for any new prescription drug, but also true for over-the-counter medications, medical devices, and more.

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Clinical Trials Trials Therapies Treatment 126

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Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

Clinical Trials

BioPharma Drive: Drug Pricing

NOVEMBER 8, 2023

A gene editing therapy developed by Vertex Pharmaceuticals and CRISPR Therapeutics can mute sickle cell disease’s most damaging symptoms. Yet treatment may not be as simple as its dramatic benefit makes it seem.

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Broad Institute

NOVEMBER 2, 2023

Q&A: How generative AI could help accelerate biomedical research By Corie Lok November 2, 2023 Breadcrumb Home Q&A: How generative AI could help accelerate biomedical research A machine learning and AI expert discusses how generative AI could be used not just to write emails and computer code, but also to analyze biological data. By Corie Lok November 2, 2023 Credit: Maria Nemchuk, Broad Communications Mehrtash Babadi is director of computational methods in Broad's Data Sciences Platform The re

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Science Daily: Pharmacology News

NOVEMBER 13, 2023

Researchers aiming to combat rising global temperatures have developed a new 'cooling glass' that can turn down the heat indoors without electricity by drawing on the cold depths of space. The new technology, a microporous glass coating, can lower the temperature of the material beneath it by 3.5 degrees Celsius at noon, and has the potential to reduce a mid-rise apartment building's yearly carbon emissions by 10 percent.

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Research 138

Drugs.com

NOVEMBER 3, 2023

FRIDAY, Nov. 3, 2023 -- The first new antibiotic for gonorrhea — the second most common sexually transmitted disease — has shown promise in a clinical trial. That news should come as a relief to public health experts, because gonorrhea.

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Trials Clinical Trials Disease Drugs 126

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Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

Clinical Trials

Drug Discovery Today

NOVEMBER 7, 2023

Researchers have built the first ever map showing how every single neuron in the nervous system of a tiny worm communicates wirelessly

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Research 124

Antidote

NOVEMBER 13, 2023

Each November is designated as Diabetes Awareness Month , an event that highlights the importance of spreading awareness about diabetes and the health issues it can cause.

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Clinical Trials Trials 122

BioPharma Drive: Drug Pricing

NOVEMBER 28, 2023

U.S. tax law changes enacted six years ago slashed large pharma companies' rates and saved them billions. Now, a push for an international floor could disrupt their R&D accounting.

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Drug Target Review

NOVEMBER 17, 2023

NK cells are among the front line of protection from infected and abnormal cells as part of the ‘innate immune response’. They recognise ‘cell stress molecules’ on the surface of infected, old, injured and cancerous cells without the need for complex pre-stimulation signals of the adaptive immune system (eg, T cells). They do not induce ‘graft versus host’ disease when transplanted for allogeneic therapy and there appears little sign of immune rejection.

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Clinical Trials

Science Daily: Pharmacology News

NOVEMBER 29, 2023

We humans are fixated on big brains as a proxy for smarts. But headless animals called brittle stars have no brains at all and still manage to learn through experience, new research reveals. These shy marine creatures have no brain to speak of -- just nerve cords running down each of their five wiggly arms. But that seems to be enough to learn by association, researchers report.

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Research 136

Drugs.com

NOVEMBER 30, 2023

THURSDAY, Nov. 30, 2023 -- Migraine sufferers would do better to talk to their doctor about a prescription drug than reaching for a bottle of ibuprofen, a new study finds.Drugs like triptans, ergots and anti-emetics can be two to five times more.

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Drug Discovery Today

NOVEMBER 7, 2023

Cancer Research UK, and the KWF Dutch Cancer Society (KWF), two of the world’s largest charitable funders of cancer research, announce a new multi-project strategic partnership to advance promising therapeutic agents for cancer through early clinical development.

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Clinical Development Research Drugs 124

Antidote

NOVEMBER 14, 2023

For Carla Greenbaum, M.D., growing up in the era of space travel and the moon landing kindled a lifelong interest in science. That interest influenced her career trajectory, and she’s now a leading investigator at Benaroya Research Institute where she has studied the natural history of type 1 diabetes (T1D) since 2000. Her work focuses on finding the cause of autoimmunity and developing targets for treatment, which she finds “incredibly exciting and inspiring—like landing on the moon!

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Research Science Treatment 121

BioPharma Drive: Drug Pricing

NOVEMBER 16, 2023

Clearance of Vertex Pharmaceuticals and CRISPR Therapeutics' Casgevy in the U.K. comes ahead of expected regulatory decisions in the U.S. and Europe.

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NIOSH Science Blog: Drugs

NOVEMBER 8, 2023

Despite legislation and improved technology, data from Massachusetts hospitals show that sharps injuries have increased in the operating room (OR) [1]. These injuries place healthcare workers at risk of exposure to bloodborne pathogens (BBPs). There is an urgent need to renew efforts to protect healthcare workers inside the operating room. The Massachusetts data highlight a gap and the need to establish a national surveillance program that would help hospitals develop further measures to prevent

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Science Daily: Pharmacology News

NOVEMBER 22, 2023

When you eagerly dig into a long-awaited dinner, signals from your stomach to your brain keep you from eating so much you'll regret it -- or so it's been thought.

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Drugs.com

NOVEMBER 28, 2023

TUESDAY, Nov. 28, 2023 -- Stem cells injected into the brains of multiple sclerosis patients appear to protect them against further damage from the degenerative disease, a new study shows.MS occurs when the body’s own immune system attacks and.

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Therapies Disease 119

Perficient: Drug Development

NOVEMBER 29, 2023

The Core of Efficiency: Choosing the Right ERP Choosing the right Enterprise Resource Planning (ERP) system is critical for ensuring optimal efficiency and future growth of your business. It is important to choose a system that seamlessly integrates with your unique processes and objectives, acting as the driving force behind your business operations.

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Research 115

Antidote

NOVEMBER 30, 2023

Despite the fact that colorectal cancer cases have been declining in the United States since the mid-1980s, it is still the third most common cancer diagnosed each year excluding skin cancer. Often shortened to colon cancer, colorectal cancer occurs when cells in the colon and/or the rectum begin to grow uncontrollably and eventually spread to other parts of the body.

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BioPharma Drive: Drug Pricing

NOVEMBER 3, 2023

The company recorded a net loss in the third quarter as it “resizes” its manufacturing footprint, and now expects revenue to come in at low end of its previous guidance.

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Broad Institute

NOVEMBER 13, 2023

Gerstner Center for Cancer Diagnostics receives additional commitment from Louis V. Gerstner, Jr., to advance technologies that could transform cancer care By Leah Eisenstadt November 14, 2023 Breadcrumb Home Gerstner Center for Cancer Diagnostics receives additional commitment from Louis V. Gerstner, Jr., to advance technologies that could transform cancer care Commitment of $20 million will propel efforts to develop, optimize, and demonstrate liquid biopsy technology along with other cancer di

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Science Daily: Pharmacology News

NOVEMBER 30, 2023

Scientists have created tiny moving biological robots from human tracheal cells that can encourage the growth of neurons across artificial 'wounds' in the lab. Using patients' own cells could permit growth of Anthrobots that assist healing and regeneration in the future with no nead for immune suppression.

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Drugs.com

NOVEMBER 21, 2023

TUESDAY, Nov. 21, 2023 -- Biologic drugs to treat asthma have been around for two decades, but a surprising number of family doctors still aren’t prescribing them to kids and adults. A new survey found that more than two in five primary care.

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Doctors Drugs 119

Perficient: Drug Development

NOVEMBER 21, 2023

Greetings, Fellow Developers, Enthusiasts, and Friends! I am thrilled to embark on a journey of exploration and learning with you as I dive into the fascinating world of Spring Boot. As I navigate this powerful framework, I’ve decided to document my experiences, insights, and newfound knowledge in a blog series. The Motivation Behind the Series: The primary motivation for initiating this blog series stems from a desire to not only solidify my understanding of Spring Boot but also to create

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Production 116