September, 2024

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Bristol Myers schizophrenia drug, the first of its kind, approved by FDA

BioPharma Drive: Drug Pricing

In testing, Cobenfy eased schizophrenia symptoms without some of the disruptive side effects typical of existing drugs. The results have been met with excitement, as well as caution.

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New approach may yield modified messenger RNAs for treating a wide range of conditions

Broad Institute

New approach may yield modified messenger RNAs for treating a wide range of conditions By Ari Navetta September 23, 2024 Breadcrumb Home New approach may yield modified messenger RNAs for treating a wide range of conditions The LEGO framework could help scientists create mRNA therapies that last longer and require smaller doses. By Ari Navetta September 23, 2024 Credit: Natalie Velez, Broad Communications Related news Messenger RNAs with multiple “tails” could lead to more effective therapeutics

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Microscale robot folds into 3D shapes and crawls

Science Daily: Pharmacology News

Researchers have created microscale robots less than 1 millimeter in size that are printed as a 2D hexagonal 'metasheet' but, with a jolt of electricity, morph into preprogrammed 3D shapes and crawl.

Research 143
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Almost 200 Chemicals Linked to Breast Cancer Are Found in Food Packaging

Drugs.com

TUESDAY, Sept. 24, 2024 -- Food sold in shrink wrap, on cardboard trays or in paper containers might contain any of nearly 200 chemicals linked to breast cancer, a new study warns.Commonly used food packaging materials contain 189 chemicals that.

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How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

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Commercial interests contribute to drug use and addiction

National Institute on Drug Abuse: Nora's Blog

Commercial interests contribute to drug use and addiction mfleming Wed, 09/25/2024 - 15:00 Nora's Blog September 26, 2024 Image ©Getty Images/ PeopleImages Biomedical sciences are bringing increased focus to social determinants of health, which the World Health Organization (WHO) defines as “the conditions in which people are born, grow, work, live, and age, the systems put in place to deal with illness, and the wider set of forces and systems shaping the conditions of daily life.” 1 Very often,

Drugs 111
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Powering the Future: Key Highlights from PPCC24 and What’s Next for Power Platform

Perficient: Drug Development

The energy was electric last week as thousands of attendees invaded MGM Grand along the Las Vegas Strip for the 3rd Annual Power Platform Community Conference (PPCC24). From groundbreaking announcements to new features unveiled during keynotes from Microsoft’s Charles Lamanna, Corporate Vice President of Business Industry and Copilot, and Jeff Teper, President of Apps and Platforms, PPCC24 offered an electrifying three days of innovation and collaboration.

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More Trending

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Looking beyond traditional oncogenic pathways to break cancer resistance

Drug Target Review

Targeted cancer therapies and treatment resistance mechanisms Targeted cancer therapies such as epidermal growth factor receptor (EGFR), Kirsten rat sarcoma virus (KRAS), or V-Raf Murine Sarcoma Viral Oncogene Homolog B (BRAF) inhibitors have made a significant positive impact in the treatment of solid tumours, specifically for patients exhibiting oncogenic mutations.

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Travel could be the best defense against aging

Science Daily: Pharmacology News

Forget about retinol night creams, researchers believe travel could be the best way to defy premature aging. An interdisciplinary study has applied the theory of entropy to tourism, finding that travel could have positive health benefits, including slowing down the signs of aging.

Research 137
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Twice-Yearly Injection Cuts HIV Risk by 96%, But Will Cost Cut Access?

Drugs.com

THURSDAY, Sept. 12, 2024 -- It could be a real breakthrough for people at risk for HIV infection: A shot given every six months that reduces their risk by a whopping 96%.That's according to new trial results released Thursday by Gilead Sciences.

Science 119
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Q&A: How Terra became a backbone of public health pathogen surveillance

Broad Institute

Q&A: How Terra became a backbone of public health pathogen surveillance By Allessandra DiCorato September 30, 2024 Breadcrumb Home Q&A: How Terra became a backbone of public health pathogen surveillance Bronwyn MacInnis and Daniel Park reflect on how Terra, a scalable and secure open-source platform for biomedical data management and analysis, is making genomics accessible to public health labs.

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Deliver Fast, Flexible Clinical Trial Insights with Spotfire

Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

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Simple and Effective Personalization with Optimizely Data Platform (ODP)

Perficient: Drug Development

As we dive into the amazing capabilities of Optimizely One , let’s shine a spotlight on the Optimizely Data Platform (ODP). This simple tool unifies all your customer data in one place, making segmentation and personalization a breeze for your marketing team. With ODP, you’ll gain a complete view of your customers’ interactions and behaviors, empowering you to create personalized experiences, optimize your email marketing campaigns, and make smarter, data-driven decisions.

Marketing 103
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Three biotechs raise $700M in rare burst of IPO activity

BioPharma Drive: Drug Pricing

The offerings by Bicara, Zenas and MBX give a glimpse into what industry insiders describe as a backlog of mature startups waiting for the right opportunity to test public markets.

Marketing 132
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Women in STEM with Kristina Torfgard

Drug Target Review

Can you tell us about your journey in the field of STEM and the challenges you encountered along the way? I am a pharmacist by training and continued with a PhD in Clinical Pharmacology. However, my goal was all the time to work with drug development in the pharma industry, so I moved on and started that journey in 1992 when I took on a role as Clinical Research Manager at AstraHässle, a mid-size Swedish pharma company.

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Scientists turn to human skeletons to explore origins of horseback riding

Science Daily: Pharmacology News

A new, wide-ranging exploration of human remains casts doubt on a long-standing theory in archaeology known as the Kurgan hypothesis -- which, among other claims, suggests that humans first domesticated horses as early as the fourth millennium B.C.

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Clinical Data Like You´ve Never Seen It Before: Why Spotfire Is the Leading Tool for Clinical Analytics

Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

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It's High Number of Guns, Not Mental Health Crises, That Drives U.S. Gun Deaths: Study

Drugs.com

WEDNESDAY, Sept. 11, 2024 -- Widespread and easy access to guns is the reason behind the shockingly high rate of firearm deaths in the United States, and not any rise in mental health problems suffered by perpetrators, a new study shows.The United.

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CDD Vault Update (September 2024)

Collaborative Drug

Chemical Safety Information: When working in a lab, you must understand the risks associated with handling chemicals. CDD Vault now displays safety information obtained from PubChem as a helpful reminder. If available, you will find hazard pictograms next to the name at the top of the molecule page.

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Revised Final Guidance on Nitrosamines Offers New Recommendations for Assessment and Control

FDA Law Blog: Biosimilars

By John W.M. Claud — Last week, FDA revised one of its two guidances relating to nitrosamines, Control of Nitrosamine Impurities in Human Drugs. Nitrosamines are impurities that can form during drug manufacturing and are considered potentially potent carcinogens. One specific kind of nitrosamines called N-nitrosamine drug substance-related impurities, or NDSRIs, are especially vexing to FDA and to industry because they mimic the structure of the specific active pharmaceutical ingredients (API),

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Summit lung cancer drug shows ‘striking’ benefit over Keytruda

BioPharma Drive: Drug Pricing

Study results provide much-anticipated details to Summit’s claim earlier this year that its drug “decisively beat” Merck’s dominant immunotherapy.

Drugs 135
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Content Hub: Data Model Simplified

Perficient: Drug Development

Sitecore Content Hub is a world-class platform for centralizing and managing content across various channels. It helps businesses organize and streamline often chaotic, messy content operations. It does this by providing an architecture or schema for content and its interconnections. A schema defines how different types of assets are structured, organized, related to each other.

Marketing 105
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New AI can ID brain patterns related to specific behavior

Science Daily: Pharmacology News

Scientists have developed a new AI algorithm that can separate brain patterns related to a particular behavior. This work promises to improve brain-computer interfaces and aid with the discovery of new brain patterns.

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FDA Approves First Flu Vaccine You Give Yourself at Home

Drugs.com

FRIDAY, Sept. 20, 2024 -- The days of waiting for a flu shot at your doctor's office or local pharmacy may be over: The U.S. Food and Drug Administration on Friday approved FluMist nasal spray as the first influenza vaccine that can be.

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The Impact of Patent Expirations on Generic Drug Markets

Drug Patent Watch

Patent expirations have a significant impact on the pharmaceutical industry, particularly on the generic drug market. When a drug’s patent expires, other manufacturers can produce and market generic versions of the drug, leading to increased competition and lower prices.

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Mastering SAS: Top Tips for Efficient Programming & Handling Large Datasets

Quanticate

SAS® (Statistical Analysis System) is a powerful tool widely used in clinical programming, data analysis, and reporting. Whether you’re working on clinical trials or handling complex data analyses, mastering SAS® programming techniques and managing large datasets efficiently are crucial for successful outcomes. In this article, we’ll explore our top 5 SAS® tips and tricks, key SAS® techniques that enhance coding efficiency, and delve into best practices for handling large datasets.

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Arch raises another $3B biotech fund in pursuit of ‘coolest’ new science

BioPharma Drive: Drug Pricing

Despite working in a restrictive funding climate, the prolific startup creator is “in the ‘taking lots of risk’ mode,” said co-founder and managing director Robert Nelsen.

Science 123
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Production Deployment and its Basics: Known to Many, Followed by Few

Perficient: Drug Development

Did you ever feel tense while taking your exams? Or you must have watched the Olympics or other sports events like cricket, football, etc. When you focus on national players during significant events, you can observe stress and anxiety in performing at that level. Similar is the situation of an IT professional during a production deployment call. This moment is crucial because it represents the end of months or years of effort, the results of which will be evaluated by those involved.

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Fungus-controlled robots tap into the unique power of nature

Science Daily: Pharmacology News

In creating a pair of new robots, researchers cultivated an unlikely component, one found on the forest floor: fungal mycelia. By harnessing mycelia's innate electrical signals, the researchers discovered a new way of controlling 'biohybrid' robots that can potentially react to their environment better than their purely synthetic counterparts.

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Treatment Could Be New Option for People Battling Ulcerative Colitis

Drugs.com

FRIDAY, Sept. 27, 2024 -- An experimental monoclonal antibody treatment appears to ease the digestive disorder ulcerative colitis in patients who've failed other medications, a new trial shows.The treatment, tulisokibart, spurred remission of.

Treatment 111
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How to Conduct Effective Generic Drug Market Analysis

Drug Patent Watch

The generic drug market is a complex and dynamic environment where multiple factors influence the availability, quality, and pricing of generic drugs. Conducting an effective market analysis is crucial for pharmaceutical companies, policymakers, and healthcare professionals to understand the market dynamics and make informed decisions.

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ACR Response Criteria in Rheumatoid Arthritis Clinical Trials

Quanticate

In rheumatoid arthritis (RA) clinical trials, accurately measuring the effectiveness of treatments is critical for determining their value in managing this chronic and debilitating condition. By evaluating improvements in joint symptoms and overall disease activity, the ACR criteria provide a clear and consistent framework for determining the efficacy of RA therapies.

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Biogen, UCB get the lupus data they’ve waited two decades for

BioPharma Drive: Drug Pricing

The companies now plan on starting this year another large study of their drug, dapirolizumab pegol, in the hopes that they can confirm its safety and effectiveness to drug regulators.

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Keypoint Newsletter: Health Equity Recap

keypoint

By Shannon Weiman In 2023 we launched a new initiative to add health equity programming to select meetings to raise awareness for health disparities in various fields and initiate discussions on how to rectify these health inequities through scientific research and discovery. These messages are of critical importance to the global research community, so we are releasing the audio recordings of these Health Equity Forums open access, to inform broader audiences about these issues and inspire them

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Climate-change-triggered 2023 mega-landslide caused Earth to vibrate for nine days

Science Daily: Pharmacology News

A landslide in a remote part of Greenland caused a 200 meter (650 foot) mega-tsunami that sloshed back and forth across a fjord for nine days, generating vibrations throughout Earth, according to a new study. The study concluded that this movement of water was the cause of a mysterious, global seismic signal that lasted for nine days and puzzled seismologists in September 2023.

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Almost 1 in 4 U.S. Adults Under 40 Have High Blood Pressure

Drugs.com

FRIDAY, Sept. 6, 2024 -- An epidemic of high blood pressure is occurring in young adults and children in the United States, a pair of new studies show.Nearly a quarter of people ages 18 to 39 have high blood pressure, with readings above the.

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AI Module Insights

Collaborative Drug

Learn how CDD Vault is utilizing AI to improve your drug discovery process.

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