August, 2024

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Scientists achieve more than 98% efficiency removing nanoplastics from water

Science Daily: Pharmacology News

Linked to cardiovascular and respiratory diseases in people, nanoplastics continue to build up, largely unnoticed, in the world's bodies of water. The challenge remains to develop a cost-effective solution to get rid of nanoplastics while leaving clean water behind. That's where Mizzou comes in. Recently, researchers created a new liquid-based solution that eliminates more than 98% of these microscopic plastic particles from water.

Disease 363
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Cell and gene therapy investment, once booming, is now in a slump

BioPharma Drive: Drug Pricing

Far fewer venture funding rounds were closed by cell and gene therapy developers over the first six months of 2024 than in prior years. Experts say there are several factors.

Therapies 356
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Ozempic, Wegovy Have Health Benefits Beyond Weight Loss, Studies Find

Drugs.com

FRIDAY, Aug.30, 2024 -- New trials are showing how the blockbuster diabetes and weight-loss meds Ozempic and Wegovy can boost health in even more ways.These two injected drugs are versions of semaglutide. In multiple new data analyses, the drugs.

Trials 299
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CDD Vault Integrates Enamine Compound Collection into AI-Powered Structural Similarity Searches

Collaborative Drug

Burlingame, CA (USA), Kyiv (Ukraine) – August 16, 2024 — Collaborative Drug Discovery (CDD), a leader in providing scientific informatics solutions, announced today that its flagship platform, CDD Vault , now includes the complete compound collection of Enamine , a leading provider of chemical compounds and early discovery services, within its AI module for structural similarity searches.

Research 278
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Bridging Innovation & Patient Care: The Growing Role of AI

Speaker: Simran Kaur, Co-founder & CEO at Tattva.Health

AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!

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Placebos reduce stress, anxiety, depression -- even when people know they are placebos

Science Daily: Pharmacology News

A study found that nondeceptive placebos, or placebos given with people fully knowing they are placebos, effectively manage stress -- even when the placebos are administered remotely.

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Greenland fossil discovery reveals increased risk of sea-level catastrophe

Science Daily: Pharmacology News

Seeds, twigs, and insect parts found under two miles of ice confirm Greenland's ice sheet melted in the recent past, the first direct evidence that the center -- not just the edges -- of the two-mile-deep ice melted away in the recent geological past. The new research indicates that the giant ice sheet is more fragile than scientists had realized until the last few years -- and reveals increased risk of sea-level catastrophe in a warmer future.

Research 364
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Link between global warming and rising sea levels

Science Daily: Pharmacology News

A new study suggests that Earth's natural forces could substantially reduce Antarctica's impact on rising sea levels, but only if carbon emissions are swiftly reduced in the coming decades. By the same token, if emissions continue on the current trajectory, Antarctic ice loss could lead to more future sea level rise than previously thought.

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Hydrogels can play Pong by 'remembering' previous patterns of electrical simulation

Science Daily: Pharmacology News

Non-living hydrogels can play the video game Pong and improve their gameplay with more experience, researchers report. The researchers hooked hydrogels up to a virtual game environment and then applied a feedback loop between the hydrogel's paddle -- encoded by the distribution of charged particles within the hydrogel -- and the ball's position -- encoded by electrical stimulation.

Research 360
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New brain-computer interface allows man with ALS to 'speak' again

Science Daily: Pharmacology News

A new brain-computer interface translates brain signals into speech with up to 97 percent accuracy. Researchers implanted sensors in the brain of a man with severely impaired speech due to amyotrophic lateral sclerosis (ALS). The man was able to communicate his intended speech within minutes of activating the system.

Research 360
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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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Record-breaking recovery of rocks that originated in Earth's mantle could reveal secrets of planet's history

Science Daily: Pharmacology News

Scientists have recovered the first long section of rocks that originated in the Earth's mantle, the layer below the crust and the planet's largest component. The rocks will help unravel the mantle's role in the origins of life on Earth, the volcanic activity generated when it melts, and how it drives the global cycles of important elements such as carbon and hydrogen.

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Bacteria encode hidden genes outside their genome--do we?

Science Daily: Pharmacology News

A 'loopy' discovery in bacteria is raising fundamental questions about the makeup of our own genome -- and revealing a potential wellspring of material for new genetic therapies.

Therapies 358
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Smallest arm bone in human fossil record sheds light on the dawn of Homo floresiensis

Science Daily: Pharmacology News

A new study reports the discovery of extremely rare early human fossils from the Indonesian island of Flores, including an astonishingly small adult limb bone. Dated to about 700,000 years old, the new findings shed light on the evolution of Homo floresiensis, the so-called 'Hobbits' of Flores whose remains were uncovered in 2003 at Liang Bua cave in the island's west.

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Scientists lay out revolutionary method to warm Mars

Science Daily: Pharmacology News

Ever since we learned that the surface of planet Mars is cold and dead, people have wondered if there is a way to make it friendlier to life. The newly proposed method is over 5,000 times more efficient than previous schemes to globally warm Mars, representing a significant leap forward in our ability to modify the Martian environment.

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How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

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Mitochondria are flinging their DNA into our brain cells

Science Daily: Pharmacology News

A new study finds that mitochondria in our brain cells frequently fling their DNA into the cells' nucleus, where the mitochondrial DNA integrates into chromosomes, possibly causing harm.

DNA 352
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Brain wiring is guided by activity even in very early development

Science Daily: Pharmacology News

In humans, the process of learning is driven by different groups of cells in the brain firing together. For instance, when the neurons associated with the process of recognizing a dog begin to fire in a coordinated manner in response to the cells that encode the features of a dog -- four legs, fur, a tail, etc. -- a young child will eventually be able to identify dogs going forward.

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Retreat of tropical glaciers foreshadows changing climate's effect on the global ice

Science Daily: Pharmacology News

As they are in many places around the globe, glaciers perched high in the Andes Mountains are shrinking. Now, researchers have uncovered evidence that the high-altitude tropical ice fields are likely smaller than they've been at any time since the last ice age ended 11,700 years ago.

Research 349
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Key to rapid planet formation

Science Daily: Pharmacology News

Researchers have developed a new model to explain the formation of giant planets such as Jupiter, which furnishes deeper insights into the processes of planet formation and could expand our understanding of planetary systems.

Research 349
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Deliver Fast, Flexible Clinical Trial Insights with Spotfire

Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

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Engineers design tiny batteries for powering cell-sized robots

Science Daily: Pharmacology News

A zinc-air microbattery could enable the deployment of cell-sized, autonomous robots for drug delivery within in the human body, as well as other applications such as locating leaks in gas pipelines.

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Turning unused signals such as Wi-Fi into energy for electronics

Science Daily: Pharmacology News

We are constantly surrounded by electromagnetic waves such as Wi-Fi. Researchers tested a device to convert this ambient energy into energy for electronic devices.

Research 347
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Rethinking the dodo

Science Daily: Pharmacology News

Researchers are setting out to challenge our misconceptions about the Dodo, one of the most well-known but poorly understood species of bird. Researchers have undertaken the most comprehensive review of the taxonomy of the Dodo and its closest relative, the Rodriguez Island Solitaire.

Research 345
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Scientists and climate change: Extreme concern and high level of engagement

Science Daily: Pharmacology News

Scientists from across academic disciplines are extremely concerned about climate change. Many of them have already changed their own lifestyles or engaged in advocacy and protest, with even more being willing to do so in future. This is evident from a large-scale survey of scientists from all over the world.

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Clinical Data Like You´ve Never Seen It Before: Why Spotfire Is the Leading Tool for Clinical Analytics

Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

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Engineers make tunable, shape-changing metamaterial inspired by vintage toys

Science Daily: Pharmacology News

Common push puppet toys in the shapes of animals and popular figures can move or collapse with the push of a button at the bottom of the toys' base. Now, a team of engineers has created a new class of tunable dynamic material that mimics the inner workings of push puppets, with applications for soft robotics, reconfigurable architectures and space engineering.

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Smart fabric converts body heat into electricity

Science Daily: Pharmacology News

Researchers have developed a smart fabric that can convert body heat and solar energy into electricity, potentially enabling continuous operation with no need for an external power source. Different sensors monitoring temperature, stress, and more can be integrated into the material.

Research 344
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Life from a drop of rain: New research suggests rainwater helped form the first protocell walls

Science Daily: Pharmacology News

New research shows that rainwater could have helped create a meshy wall around protocells 3.8 billion years ago, a critical step in the transition from tiny beads of RNA to every bacterium, plant, animal, and human that ever lived.

RNA 340
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Say 'aah' and get a diagnosis on the spot: is this the future of health?

Science Daily: Pharmacology News

A computer algorithm has achieved a 98% accuracy in predicting different diseases by analyzing the color of the human tongue. The proposed imaging system can diagnose diabetes, stroke, anemia, asthma, liver and gallbladder conditions, COVID-19, and a range of vascular and gastrointestinal issues, according to new research.

Disease 340
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3D-printed blood vessels bring artificial organs closer to reality

Science Daily: Pharmacology News

Lab-grown organs are a long-time 'holy grail' of organ engineering that has yet to be achieved, but new research has brought that goal a big step closer to reality using a new 3D-printing method called co-SWIFT. co-SWIFT prints branching networks of double-layered vessels that are infused with smooth muscle cells and endothelial cells into living human cardiac tissue, and can even replicate patient-specific vascular structures,indicating that it could one day be used for personalized medicine.