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The Acute Respiratory Distress Syndrome (ARDS), often preceded by acute lung injury (ALI), is characterized by the accumulation of inflammatory fluid in the lung alveoli, leaky alveolar epithelium and endothelium, and overexpression of pro-inflammatory cytokines. This progression from ALI to ARDS is a major contributor to the high mortality observed in COVID-19 patients.
Linked to cardiovascular and respiratory diseases in people, nanoplastics continue to build up, largely unnoticed, in the world's bodies of water. The challenge remains to develop a cost-effective solution to get rid of nanoplastics while leaving clean water behind. That's where Mizzou comes in. Recently, researchers created a new liquid-based solution that eliminates more than 98% of these microscopic plastic particles from water.
Far fewer venture funding rounds were closed by cell and gene therapy developers over the first six months of 2024 than in prior years. Experts say there are several factors.
A common fatty acid may help restore healthy vaginal bacteria after infection By Ari Navetta August 19, 2024 Breadcrumb Home A common fatty acid may help restore healthy vaginal bacteria after infection Treatments using oleic acid, a naturally occurring oil used in cells, could improve treatment of recurrent bacterial vaginosis infections. By Ari Navetta August 19, 2024 Credit: Meilin Zhu Lactobacillus iners after treatment with oleic acid Related people Paul Blainey Related programs Metabolomi
Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.
The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven
FRIDAY, Aug.30, 2024 -- New trials are showing how the blockbuster diabetes and weight-loss meds Ozempic and Wegovy can boost health in even more ways.These two injected drugs are versions of semaglutide. In multiple new data analyses, the drugs.
What are the main therapeutic areas beyond oncology where ADCs show potential? A number of areas represent significant opportunities for Antibody Drug Conjugates (ADCs) beyond oncology, leveraging their ability to deliver therapeutic agents specifically to diseased cells or tissues while minimising off-target effects. The development of ADCs in these areas is ongoing, with several preclinical and clinical studies exploring their potential.
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What are the main therapeutic areas beyond oncology where ADCs show potential? A number of areas represent significant opportunities for Antibody Drug Conjugates (ADCs) beyond oncology, leveraging their ability to deliver therapeutic agents specifically to diseased cells or tissues while minimising off-target effects. The development of ADCs in these areas is ongoing, with several preclinical and clinical studies exploring their potential.
Alzheimer’s disease research and drug development is evolving at a rapid pace. Decades of research has led to the approval of the first disease-modifying drugs and new pathological discoveries.
A study found that nondeceptive placebos, or placebos given with people fully knowing they are placebos, effectively manage stress -- even when the placebos are administered remotely.
The funding from Apple Tree Partners will help the startup advance an antiviral drug pipeline that includes a COVID treatment nearing mid-stage testing.
Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.
FRIDAY, Aug. 23, 2024 -- Research has already proven that the blockbuster weight-loss drug Wegovy (semaglutide) can slash a person's odds for heart attacks and strokes, and now more data from the same trial suggests that's even true for very ill.
Can you tell us about your journey in the field of STEM and the challenges you encountered along the way? I grew up in California where I developed a natural curiosity to understand how a living organism functions. Majoring in physiology in college allowed me to nourish this interest, and I knew medicine would be my path as it enabled me to learn the structure and function of the human body.
This post is the first in a series of four about estimating project hours. Part 1: Sandbagging & Lowballing Coming Soon: Part 2: Dependencies & Creep Part 3: Assumptions & Uncertainty Part 4: The Emotional Conclusion Estimating is a precarious business – part science, a lot of guesswork, and a bit of psychic magic! The goal is to forecast the effort, time, and cost of a project with enough accuracy to avoid disaster.
Scientists have restored the brain's waste-clearing process in aging mice, offering potential new treatment for Alzheimer's and Parkinson's using existing drugs.
Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.
Through a new deal, Roche has exclusive rights to Sangamo molecules designed to repress the gene that makes “tau,” a protein many scientists view as a main driver of Alzheimer’s.
Inventory Search Interface: The new CDD Vault Inventory tab can be enabled by the CDD Support Team. If you wish to enable this tab in your Vault please have your vault administrator contact support@collaborativedrug.com.
WEDNESDAY, Aug. 21, 2024 -- The first mpox vaccine doses from the United States are set to arrive next week in the Congo, the epicenter of an ongoing mpox outbreak in Africa.The doses come not a moment too soon: Just last week, the World Health.
Each Labor Day we honor workers and the role they play in building a strong and prosperous nation. Much like the first Labor Day more than a century ago, many of us mark this federal holiday with festivities such as parades or picnics. This year, as you head out to celebrate the end of summer with friends and loved ones, I urge you to take a moment to reflect on the contributions of the workers all around us.
Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic
We are witnessing a sea-change in the way data is managed by banks and financial institutions all over the world. Data being commoditized and, in some cases, even monetized by banks is the order of the day. Though this seems to be at a stage where some more push is required in terms of adoption in the risk management function. Traditional risk managers, by their job definition, are highly cautious of the result sets provided by the analytics teams.
Seeds, twigs, and insect parts found under two miles of ice confirm Greenland's ice sheet melted in the recent past, the first direct evidence that the center -- not just the edges -- of the two-mile-deep ice melted away in the recent geological past. The new research indicates that the giant ice sheet is more fragile than scientists had realized until the last few years -- and reveals increased risk of sea-level catastrophe in a warmer future.
Recent data from J.P. Morgan indicates early-stage startups are getting smaller upfront payments in alliances than a few years ago, a trend industry insiders attribute to weaker leverage in deal talks.
Burlingame, CA (USA), Kyiv (Ukraine) – August 16, 2024 — Collaborative Drug Discovery (CDD), a leader in providing scientific informatics solutions, announced today that its flagship platform, CDD Vault , now includes the complete compound collection of Enamine , a leading provider of chemical compounds and early discovery services, within its AI module for structural similarity searches.
FRIDAY, Aug. 16, 2024 -- As syphilis cases surge throughout the United States, the U.S. Food and Drug Administration on Friday approved the first diagnostic at-home test to spot the bacterial disease."This is the first at-home, over-the-counter.
A new study suggests that Earth's natural forces could substantially reduce Antarctica's impact on rising sea levels, but only if carbon emissions are swiftly reduced in the coming decades. By the same token, if emissions continue on the current trajectory, Antarctic ice loss could lead to more future sea level rise than previously thought.
Non-living hydrogels can play the video game Pong and improve their gameplay with more experience, researchers report. The researchers hooked hydrogels up to a virtual game environment and then applied a feedback loop between the hydrogel's paddle -- encoded by the distribution of charged particles within the hydrogel -- and the ball's position -- encoded by electrical stimulation.
A new brain-computer interface translates brain signals into speech with up to 97 percent accuracy. Researchers implanted sensors in the brain of a man with severely impaired speech due to amyotrophic lateral sclerosis (ALS). The man was able to communicate his intended speech within minutes of activating the system.
Scientists have recovered the first long section of rocks that originated in the Earth's mantle, the layer below the crust and the planet's largest component. The rocks will help unravel the mantle's role in the origins of life on Earth, the volcanic activity generated when it melts, and how it drives the global cycles of important elements such as carbon and hydrogen.
A 'loopy' discovery in bacteria is raising fundamental questions about the makeup of our own genome -- and revealing a potential wellspring of material for new genetic therapies.
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