Drug Target Review

JULY 4, 2023

Over the last two decades, an increasing number of Antibody Drug Conjugate (ADC) therapeutics have been approved for oncology indications. These therapies have broadened treatment options for patients to expand beyond the more traditional small molecule drug alternatives. Through their unique modes of action, ADCs have been heralded as having the potential to positively impact not only cancer patient outcomes but also quality of life, an increasingly important factor in treatment decisions for t

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BioPharma Drive: Drug Pricing

JULY 6, 2023

Five years after helping launch Allogene Therapeutics, Pfizer is backing another developer of “off-the-shelf” cell therapies in a deal that gives the drugmaker the chance to acquire a multiple myeloma treatment.

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Drugs.com

JULY 5, 2023

WEDNESDAY, July 5, 2023 -- A new blood test approved by the U.S. Food and Drug Administration can predict imminent preeclampsia, helping pregnant women who are at risk for this severe and sometimes deadly form of high blood pressure. The test can.

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Perficient: Drug Development

JULY 5, 2023

Insite is now Configured Commerce. In this blog, we will learn below points: Replacing an existing page in Spire Example of replacing an existing page Implementation in Local machine Replacing an existing widget in Spire Example of replacing an existing widget Implementation in Local machine In this blog post, we will explore the process of replacing existing pages and widgets in Spire, a popular content management system.

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Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

Treatment

ProRelix Research

JULY 6, 2023

Biosimilar clinical trials and study designs’ Considerations The rising prevalence and large market share of biological products emphasize their importance as treatment options for several cancers and autoimmune diseases. In […] The post Biosimilar clinical trials and study designs’ considerations appeared first on ProRelix Research.

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Clinical Trials Biosimilars Trials Treatment 105

Science Daily: Pharmacology News

JULY 4, 2023

A detailed analysis of the dietary habits of elephants showed surprising variation from meal to meal, which could have important ramifications for wildlife protection and conservation strategies.

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BioPharma Drive: Drug Pricing

JULY 5, 2023

Phase 2 results show a pill the company is developing is competitive with other oral medicines in testing against psoriasis, among them the TYK2 inhibitors that have drawn significant industry interest.

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Drugs 111

Drugs.com

JULY 5, 2023

WEDNESDAY, July 5, 2023 -- For nearly three decades, daily antiretroviral pills have offered patients living with HIV a highly effective way to keep their infection under control. But some patients, particularly those beset by homelessness, drug.

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Perficient: Drug Development

JULY 6, 2023

The AEM Style System allows the template creator to define style classes in the component’s content policy as well as page policy so that the content author can select them while modifying the component on the page. These styles can be visual variations of components, making them more versatile. Use Case: The Style System offers a consistent solution to both templates and content author requirements: a) Style classes can be defined by template authors in component content policies. b) When editi

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KIF1A

JULY 29, 2023

#ScienceSaturday posts share exciting scientific developments and educational resources with the KAND community. Each week, Dr. Dylan Verden of KIF1A.ORG summarizes newly published KIF1A-related research and highlights progress in rare disease research and therapeutic development. KIF1A in New York: The 2023 KAND Family & Scientific Engagement Conference We won’t be posting next Saturday, but not for a lack of science!

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Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

Clinical Trials

ProRelix Research

JULY 26, 2023

Ensuring the safety and efficacy of new drugs, medical devices, and biological products does not end once the treatment is approved or is on the market but extends to the […] The post Pharmacovigilance (PV) Services at a Glance appeared first on ProRelix Research.

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Drug Target Review

JULY 5, 2023

The cell line development stage The cell line development (CLD) stage begins with gene optimisation for high expression, followed by insertion of the genes of interest (GOIs) into a mammalian host cell line. Typically, this will be a Chinese hamster ovary (CHO) cell line, with alternatives such as murine, human and even duck embryonic cell lines having been used.

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BioPharma Drive: Drug Pricing

JULY 10, 2023

Three reports from Iceland spurred the EMA to evaluate whether certain Novo Nordisk drugs, including Ozempic, might cause thoughts of self harm.

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Regulations Drugs 114

Drugs.com

JULY 6, 2023

THURSDAY, July 6, 2023 -- Curious about what the differences are between hepatitis A, B, C, D and E? If so, you’ve come to the right place. Here, experts break down hepatitis infection by type to reveal what it is, the most common symptoms, how.

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Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

Clinical Trials

Perficient: Drug Development

JULY 4, 2023

A small tip can be a lifesaver when it comes to customizing a platform or an existing system. It’s crucial to first grasp the implementation details and then follow the correct path to add new functionality or make changes to existing features. However, if you’re unfamiliar with a particular area of the system and are tasked with making a specific change, it can be time-consuming to identify where to start and exactly where to make the necessary modifications to meet the requirement.

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Antidote

JULY 27, 2023

Before any new therapy can be put on the market, it must be tested to ensure its safety and effectiveness, and the research for this process is done through clinical trials. Clinical trials evaluate new drugs, devices, packaging, and behaviors in order to determine if these potential therapies work for particular conditions or patient populations.

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Science Daily: Pharmacology News

JULY 25, 2023

Important ocean currents that redistribute heat, cold and precipitation between the tropics and the northernmost parts of the Atlantic region will shut down around the year 2060 if current greenhouse gas emissions persist. This is the conclusion based on new calculations that contradict the latest report from the IPCC.

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Drug Target Review

JULY 7, 2023

When targeted gene editing became a reality more than ten years ago, many people hoped for a revolutionary tsunami of new medical treatments. In the wake of the Human Genome Project, the promise of precision medicine is marching forward, yet the clinic has experienced a mere trickle of new therapeutics so far. The reasons for this are multifaceted, including concerns over the safety of directly altering DNA sequences and subsequent regulatory restrictions that have arisen as a result.

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Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

Clinical Trials

BioPharma Drive: Drug Pricing

JULY 17, 2023

For $500 million, Novartis will acquire DTx Pharma and its preclinical neurological disease drugs, marking the Swiss company’s latest investment in gene-silencing medicines.

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Drugs.com

JULY 6, 2023

THURSDAY, July 6, 2023 -- Did you know the U.S. Centers for Disease Control and Prevention estimates that there were nearly 68,000 new cases of acute hepatitis C in 2020 and over 107,000 newly reported cases of chronic hepatitis C? To help you.

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Perficient: Drug Development

JULY 31, 2023

In a comedy special, Jerry Seinfeld once humorously said, “I saw a study that said speaking in front of a crowd is considered the number one fear of the average person. I found that amazing. Number two was death. Death was number two? This means to the average person if you have to be at a funeral, you would rather be in the casket than doing the eulogy.” The crowd roared with laughter.

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KIF1A

JULY 22, 2023

#ScienceSaturday posts share exciting scientific developments and educational resources with the KAND community. Each week, Dr. Dylan Verden of KIF1A.ORG summarizes newly published KIF1A-related research and highlights progress in rare disease research and therapeutic development. KIF1A-Related Research A Plant Flavonol Rescues a Pathogenic Mutation Associated with Kinesin in Neurons We’ve spoken in the past about the power of worms: C. elegans models were used by Dr.

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PLOS: DNA Science

JULY 27, 2023

Determining the sequence of building blocks of entire genomes – aka genomics – first came to public attention in the 1990s, with the race to decode the first human genomes. Today, smartphones can carry our personal genome sequences. Genomics applies to all species, revealing evolution in action, because we all use the same genetic code – that is, the correspondence between DNA sequences and the amino acid sequences of proteins.

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Drug Target Review

JULY 5, 2023

What is a microscopy tech centre and how do they assist drug discovery research? We work in a unique shared facility that is completely open access, meaning our tech centre is open to anyone and everyone, regardless of affiliation or experience. Our goal is to provide easy access to multimillion-dollar microscopes that would otherwise be unavailable to a lot of researchers.

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BioPharma Drive: Drug Pricing

JULY 31, 2023

According to the company, FDA officials have signaled openness to using a surrogate endpoint for assessing accelerated approval of a treatment for limb-girdle muscular dystrophy.

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Disease FDA Treatment Drugs 98

Drugs.com

JULY 4, 2023

TUESDAY, July 4, 2023 -- Bacteria found in hospital patients in Ukraine is showing extreme antibiotic resistance, making it harder to treat the wounded and ill in this war-torn country, new research warns. “I am quite thick-skinned and have.

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Perficient: Drug Development

JULY 26, 2023

At Perficient, we are proud to work with incredible people who give their time and talent to support our clients and communities. Through our People Promise , we strive to challenge, champion, and celebrate the difference that our colleagues are making. For Louise Kraus, a business coordinator based in New Jersey, each day offers the chance to discover new concepts and continue growing as a leader.

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Broad Institute

JULY 20, 2023

A look back at the first year of NeuroDev By Makenzie Kohler July 20, 2023 Breadcrumb Home A look back at the first year of NeuroDev Researchers are working to characterize the genetic and phenotypic data of people with neurodevelopmental conditions in Kenya and South Africa. By Makenzie Kohler July 20, 2023 Credit: Aga Khan University Institute for Human Development NeuroDev researchers from Kenya, South Africa, and the United States at a meeting in Nairobi, Kenya.

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Science Daily: Pharmacology News

JULY 18, 2023

No, oxygen didn't catalyze the swift blossoming of Earth's first multicellular organisms. The result defies a 70-year-old assumption about what caused an explosion of oceanic fauna hundreds of millions of years ago.

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Drug Target Review

JULY 5, 2023

Induced pluripotent stem cell (iPSC) therapies have the potential to treat a wide variety of devastating diseases. iPSC-derived lymphocytes, eg, T cells and natural killer (NK) cells, engineered to express targeting molecules such as chimeric antigen receptors (CARs) have shown clinical promise to treat haematological malignancies. More recently, iPSC-derived myeloid cells are being developed to treat both haematological malignancies and solid tumours due to their ability to infiltrate and modul

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BioPharma Drive: Drug Pricing

JULY 28, 2023

The British pharma is deepening its investment in genetic medicine through a deal for a group of Pfizer’s gene therapy delivery tools, while the New York giant cuts back.

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Drugs.com

JULY 5, 2023

WEDNESDAY, July 5, 2023 -- Heather Anderson, a star Australian rules football player who died last November, is the first female professional athlete to be diagnosed with chronic traumatic encephalopathy, or CTE. "She is the first female athlete.

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Perficient: Drug Development

JULY 17, 2023

Perficient is proud of our people-first, award-winning culture that promises to challenge, champion, and celebrate all our colleagues. Perficient is always looking to hire thought leaders and difference makers, and therefore, identifying top talent is essential to our mission. Katie Burwell , a senior talent acquisition specialist, is helping to grow our talented team of experts.

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