May, 2024

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AI headphones let wearer listen to a single person in a crowd, by looking at them just once

Science Daily: Pharmacology News

Engineers have developed an artificial intelligence system that lets someone wearing headphones look at a person speaking for three to five seconds to 'enroll' them. The system then plays just the enrolled speaker's voice in real time, even as the pair move around in noisy environments.

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Investors put $400M into biotech licensing obesity drugs from China

BioPharma Drive: Drug Pricing

The biotech, tentatively named Hercules CM Newco, has rights to three incretin drugs discovered by Jiangsu Hengrui Pharmaceuticals, two of which are in clinical testing.

Licensing 142
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New gene delivery vehicle shows promise for human brain gene therapy

Broad Institute

New gene delivery vehicle shows promise for human brain gene therapy By Allessandra DiCorato May 16, 2024 Breadcrumb Home New gene delivery vehicle shows promise for human brain gene therapy Scientists have engineered an adeno-associated virus (AAV) that efficiently crosses the blood-brain barrier in human cell models and delivers genes throughout the brain in humanized mice.

Therapies 137
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Stomach Paralysis Risk May Rise in People Taking Ozempic and Similar Drugs

Drugs.com

MONDAY, May 20, 2024 -- New, real-world research confirms that the blockbuster weight-loss drugs that millions of Americans have been taking to shed pounds can trigger stomach paralysis in some patients.“Although these drugs do work and should be.

Drugs 133
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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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Understanding colon cancer screening guidelines

Antidote

Colorectal cancer, often shortened just to colon cancer, is the third most commonly diagnosed cancer in the United States aside from skin cancers. While there are treatments available, including radiation and chemotherapy, the most important aspect of successful treatment is early detection — which is why knowing the colon cancer screening guidelines is essential.

Treatment 119
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Your Idea Factory – Quality Innovation from Quantity

Perficient: Drug Development

Quality innovation is not for the weak at heart! Innovation myths may have you thinking it is for the lucky or the extremely talented – that’s not true. Pablo Picasso said, “Inspiration exists, but it has to find you working.” Thomas Edison quipped, “Opportunity is missed by most people because it is dressed in overalls and looks like work.” In this blog post, I want to focus on a different quote with the same intent.

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Patient dies in Pfizer study of Duchenne gene therapy

BioPharma Drive: Drug Pricing

Pfizer said the patient, a young boy who was treated earlier last year, had died suddenly. The company is working with trial researchers to investigate further.

Therapies 144
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#WhyIScience Q&A: How a computational biologist balances work with life as an elite rower

Broad Institute

#WhyIScience Q&A: How a computational biologist balances work with life as an elite rower By Allessandra DiCorato May 2, 2024 Breadcrumb Home #WhyIScience Q&A: How a computational biologist balances work with life as an elite rower Liz Martin reflects on how her career in cancer biology complements her intense training on the water. By Allessandra DiCorato May 2, 2024 Credit: Lisa Worthy Liz Martin, an elite rower and a computational biologist at the Broad, in a lightweight women's quad at the 2

Science 124
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Plant-Based Diets Lower Risk of Heart Trouble, Cancer and Death

Drugs.com

THURSDAY, May 16, 2024 -- Following a vegetarian or vegan diet might just buy you a longer, healthier life, a new review finds.Staying away from meat was tied to a reduced risk of heart disease, cancer and early death, researchers reported in a.

Disease 130
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On National Cancer Survivors Day, celebrating the power of research

Antidote

This Sunday, June 2, is National Cancer Survivors Day , designed to be a celebration for those who have survived cancer and an inspiration for those recently diagnosed. Since 1991, the national cancer death rate has dropped by 33% , partially due to advancements in treatment, early detection, and reduced smoking rates.

Research 119
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How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

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#ScienceSaturday: May 4, 2024

KIF1A

#ScienceSaturday posts share exciting scientific developments and educational resources with the KAND community. Each week, Dr. Dylan Verden of KIF1A.ORG summarizes newly published KIF1A-related research and highlights progress in rare disease research and therapeutic development. KIF1A-Related Research Clinical and Genetic Characterization of a Cohort of Brazilian Patients With Congenital Ataxia KAND is a rare disorder, but each new patient makes it slightly less so.

Science 116
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AI systems are already skilled at deceiving and manipulating humans

Science Daily: Pharmacology News

Many artificial intelligence (AI) systems have already learned how to deceive humans, even systems that have been trained to be helpful and honest. Researchers describe the risks of deception by AI systems and call for governments to develop strong regulations to address this issue as soon as possible.

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Ajax, aiming for a better JAK drug, raises $95M to begin first tests

BioPharma Drive: Drug Pricing

Goldman Sachs and Eli Lilly are among those backing the startup, which claims its prospect could be more potent than the myelofibrosis therapies that have come to market in recent years.

Therapies 130
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Navigating Trust and Data in Healthcare Marketing

Perficient: Drug Development

In the ever-evolving landscape of healthcare, trust reigns supreme. As consumers increasingly rely on data to inform their decisions, the healthcare industry faces a pressing need to not only meet but exceed expectations. With disruptive forces emerging from various corners, healthcare organizations find themselves in a race to create personalized experiences that foster lasting engagement and trust.

Marketing 111
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Deliver Fast, Flexible Clinical Trial Insights with Spotfire

Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

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There's a New Set of COVID Variants Called FLiRT: What You Need to Know

Drugs.com

WEDNESDAY, May 8, 2024 -- The virus behind COVID has mutated again, this time producing variants nicknamed FLiRT, the U.S. Centers for Disease Control and Prevention (CDC) has reported.The variants are appearing in wastewater sampling, the CDC.

Virus 130
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Who decides whether you get into a clinical trial?

Antidote

One may choose to participate in a clinical trial for many reasons. Volunteering often has multiple benefits, from advancing medical research to gaining access to cutting-edge medical care. However, deciding to enroll in a clinical trial is only one part of the process.

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When Worlds Collide: The Theory of Real-World Evidence Meets Reality

FDA Law Blog: Biosimilars

By Jeffrey N. Gibbs & Ana Loloei & Véronique Li, Senior Medical Device Regulation Expert — FDA has long touted the use of real-world evidence ( RWE ). Extolling RWE, FDA has said “RWE can be leveraged to bring new products to market, evaluate the safety and effectiveness of existing products for new uses, and assess the continued performance and safety of products once on the market.

FDA 109
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Stretchable e-skin could give robots human-level touch sensitivity

Science Daily: Pharmacology News

A stretchy electronic skin could equip robots and other devices with the same softness and touch sensitivity as human skin, opening up new possibilities to perform tasks that require a great deal of precision and control of force.

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Clinical Data Like You´ve Never Seen It Before: Why Spotfire Is the Leading Tool for Clinical Analytics

Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

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Drug patents protect pharma profits. Track when they’ll expire here.

BioPharma Drive: Drug Pricing

Intellectual property is the foundation of the drug industry’s business model. This database will track key patent expiry dates for 30 top-selling medicines.

Drugs 131
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Handling Not Allowed Reflection Method in Sitecore

Perficient: Drug Development

Recently, to meet project requirements, we customized and expanded the functionality of the “General Link” feature by incorporating a new “Telephone Link” feature. Everything was working correctly on our local project instance, but we got the below-listed error when the changes were deployed on the higher environment. Exception: Sitecore.Exceptions.AccessDeniedException Message: Calling Fieldtypes.ExtendedGeneralLink.ExtendedGeneralLinkForm.OnModeChange method through ref

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Costs, Side Effects Drive Folks to Quit New Weight-Loss Meds

Drugs.com

THURSDAY, May 23, 2024 -- Three months after starting one of the new GLP-1 weight-loss drugs, more than a quarter of patients have already quit the medications, and by a year from first use more than a third have stopped, new research shows.Reasons.

Research 124
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Antidote to be announced as Corporate Honoree at MSAA Improving Lives Benefit

Antidote

We are thrilled to be honored as the Multiple Sclerosis Association of America’s Corporate Honoree at their 10th annual Improving Lives Benefit on May 15! This inspiring event supports MSAA’s free programs and services and honors key players in the MS research space.

Research 105
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Cell Line Services FAQ

Crown Bioscience

This post delves into some frequently asked questions about Omni Screen and its unique capabilities in providing compliant, large-scale cell line screening solutions that are not only cutting-edge but also aligned with industry standards and regulations. Whether you're a researcher, a biotech professional, or someone keen on understanding the nuances of cell line screening, this discussion will provide valuable insights into how Crown Bioscience can support your scientific endeavors.

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Scientists work out the effects of exercise at the cellular level

Science Daily: Pharmacology News

The health benefits of exercise are well known but new research shows that the body's response to exercise is more complex and far-reaching than previously thought. In a study on rats, a team of scientists has found that physical activity causes many cellular and molecular changes in all 19 of the organs they studied in the animals.

Research 139
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Lilly to pour $5B more into expanding Zepbound, Mounjaro production

BioPharma Drive: Drug Pricing

The planned spending on new facilities in Lebanon, Indiana, brings its total commitment to the site to $9 billion, the largest single manufactuing investment in company history.

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Perficient Awarded as HCL Software’s Gold Reseller Award

Perficient: Drug Development

We are proud to announce Perficient has been awarded HCL Software’s Gold Reseller Award! This award comes as recognition for our continued collaboration and outstanding performance in regard to sales and delivery in 2023. As an HCL Software strategic partner, we actively drive innovation into HCL’s roadmap and collaborate closely from a product innovation and support perspective.

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Ozempic Lowers Odds for Death, Illness in People With Kidney Disease and Type 2 Diabetes

Drugs.com

FRIDAY, May 24, 2024 -- Ozempic provides a wide variety of health benefits for people with kidney disease and type 2 diabetes, a major clinical trial has found. The drug significantly reduces the risk of severe kidney events, heart problems and.

Disease 124
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Women in Stem with Stefanie Flückiger-Mangual

Drug Target Review

Can you tell us about your journey in the field of STEM and the challenges you encountered along the way? My journey in STEM has been both challenging and immensely fulfilling. Early in my career, I had a bad experience in one of my first jobs, helping in the lab as a young student. My professor’s seeming support of my work quickly shifted into a more personal interest in me.

Therapies 105
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Scientists work out the effects of exercise at the cellular level

Broad Institute

Scientists work out the effects of exercise at the cellular level By Allessandra DiCorato May 1, 2024 Breadcrumb Home Scientists work out the effects of exercise at the cellular level Prolonged physical activity in rats results in profound changes to RNA, proteins, and metabolites in nearly all tissues, providing clues to many human health conditions.

RNA 143
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Scientists map networks regulating gene function in the human brain

Science Daily: Pharmacology News

A consortium of researchers has produced the largest and most advanced multidimensional maps of gene regulation networks in the brains of people with and without mental disorders. These maps detail the many regulatory elements that coordinate the brain's biological pathways and cellular functions. The research used postmortem brain tissue from over 2,500 donors to map gene regulation networks across different stages of brain development and multiple brain-related disorders.

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CG follows big IPO with new results for bladder cancer drug

BioPharma Drive: Drug Pricing

Newly disclosed Phase 3 results presented Friday match findings the biotech disclosed last year, while offering a more comprehensive look at how its drug stacks up to rival therapies.

Drugs 122
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Using Optimizely Content Delivery API for data migration

Perficient: Drug Development

Optimizely Content Delivery API is very well known for building headless CMS, to connect to Single Page Apps, mobile apps, etc. However I also found that come in handy in terms of data migration. With the Content Delivery API, you can easily retrieve detailed information of source content in JSON format and map it to your target application. In this article, I will give a brief instruction on how to migrate data between Optimizely Content Cloud applications using the API.

Packaging 105
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Do Fish Oil Supplements Help or Harm the Heart?

Drugs.com

WEDNESDAY, May 22, 2024 -- Folks regularly taking fish oil supplements might not be helping their health as much as they might think, a new study suggests.Regular use of fish oil supplements could increase the risk of first-time heart disease and.

Disease 122