May, 2024

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The Potential of Cannabichromene (CBC) as a Therapeutic Agent [Minireview]

ASPET

There is a growing interest in the use of medicinal plants to treat a variety of diseases, and one of the most commonly used medicinal plants globally is Cannabis sativa. The two most abundant cannabinoids ( 9 -tetrahydrocannabinol and cannabidiol) have been governmentally approved to treat selected medical conditions; however, the plant produces over 100 cannabinoids, including cannabichromene (CBC).

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A simple quantum internet with significant possibilities

Science Daily: Pharmacology News

It's one thing to dream up a quantum internet that could send hacker-proof information around the world via photons superimposed in different quantum states. It's quite another to physically show it's possible. That's exactly what physicists have done, using existing Boston-area telecommunication fiber, in a demonstration of the world's longest fiber distance between two quantum memory nodes to date.

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Patient dies in Pfizer study of Duchenne gene therapy

BioPharma Drive: Drug Pricing

Pfizer said the patient, a young boy who was treated earlier last year, had died suddenly. The company is working with trial researchers to investigate further.

Therapies 144
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New gene delivery vehicle shows promise for human brain gene therapy

Broad Institute

New gene delivery vehicle shows promise for human brain gene therapy By Allessandra DiCorato May 16, 2024 Breadcrumb Home New gene delivery vehicle shows promise for human brain gene therapy Scientists have engineered an adeno-associated virus (AAV) that efficiently crosses the blood-brain barrier in human cell models and delivers genes throughout the brain in humanized mice.

Therapies 137
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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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Stomach Paralysis Risk May Rise in People Taking Ozempic and Similar Drugs

Drugs.com

MONDAY, May 20, 2024 -- New, real-world research confirms that the blockbuster weight-loss drugs that millions of Americans have been taking to shed pounds can trigger stomach paralysis in some patients.“Although these drugs do work and should be.

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Understanding colon cancer screening guidelines

Antidote

Colorectal cancer, often shortened just to colon cancer, is the third most commonly diagnosed cancer in the United States aside from skin cancers. While there are treatments available, including radiation and chemotherapy, the most important aspect of successful treatment is early detection — which is why knowing the colon cancer screening guidelines is essential.

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Participants of pioneering CRISPR gene editing trial see vision improve

Science Daily: Pharmacology News

About 79% of clinical trial participants experienced measurable improvement after receiving experimental, CRISPR-based gene editing that is designed to fix a rare form of blindness, according to a new article.

Trials 144
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Investors put $400M into biotech licensing obesity drugs from China

BioPharma Drive: Drug Pricing

The biotech, tentatively named Hercules CM Newco, has rights to three incretin drugs discovered by Jiangsu Hengrui Pharmaceuticals, two of which are in clinical testing.

Licensing 142
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#WhyIScience Q&A: How a computational biologist balances work with life as an elite rower

Broad Institute

#WhyIScience Q&A: How a computational biologist balances work with life as an elite rower By Allessandra DiCorato May 2, 2024 Breadcrumb Home #WhyIScience Q&A: How a computational biologist balances work with life as an elite rower Liz Martin reflects on how her career in cancer biology complements her intense training on the water. By Allessandra DiCorato May 2, 2024 Credit: Lisa Worthy Liz Martin, an elite rower and a computational biologist at the Broad, in a lightweight women's quad at the 2

Science 124
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Plant-Based Diets Lower Risk of Heart Trouble, Cancer and Death

Drugs.com

THURSDAY, May 16, 2024 -- Following a vegetarian or vegan diet might just buy you a longer, healthier life, a new review finds.Staying away from meat was tied to a reduced risk of heart disease, cancer and early death, researchers reported in a.

Disease 130
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How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

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On National Cancer Survivors Day, celebrating the power of research

Antidote

This Sunday, June 2, is National Cancer Survivors Day , designed to be a celebration for those who have survived cancer and an inspiration for those recently diagnosed. Since 1991, the national cancer death rate has dropped by 33% , partially due to advancements in treatment, early detection, and reduced smoking rates.

Research 119
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#ScienceSaturday: May 4, 2024

KIF1A

#ScienceSaturday posts share exciting scientific developments and educational resources with the KAND community. Each week, Dr. Dylan Verden of KIF1A.ORG summarizes newly published KIF1A-related research and highlights progress in rare disease research and therapeutic development. KIF1A-Related Research Clinical and Genetic Characterization of a Cohort of Brazilian Patients With Congenital Ataxia KAND is a rare disorder, but each new patient makes it slightly less so.

Science 116
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Wild orangutan treats wound with pain-relieving plant

Science Daily: Pharmacology News

A wild orangutan was observed applying a plant with known medicinal properties to a wound, a first for a wild animal.

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Drug patents protect pharma profits. Track when they’ll expire here.

BioPharma Drive: Drug Pricing

Intellectual property is the foundation of the drug industry’s business model. This database will track key patent expiry dates for 30 top-selling medicines.

Drugs 133
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Deliver Fast, Flexible Clinical Trial Insights with Spotfire

Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

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Lab Innovations 2024 to champion sustainability and innovation

Drug Discovery Today

London, 25/04/2024: The lab industry’s largest annual trade show is returning to the NEC, Birmingham, on October 30 and 31, 2024, to showcase sustainability and the latest innovations from the lab industry. The highly anticipated event will see thousands of attendees from across the lab sector descend on the NEC to meet with over 200 of the industry’s leading companies and enjoy the show’s world-leading conference programme, hosted across four free-to-attend theatres.

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There's a New Set of COVID Variants Called FLiRT: What You Need to Know

Drugs.com

WEDNESDAY, May 8, 2024 -- The virus behind COVID has mutated again, this time producing variants nicknamed FLiRT, the U.S. Centers for Disease Control and Prevention (CDC) has reported.The variants are appearing in wastewater sampling, the CDC.

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Who decides whether you get into a clinical trial?

Antidote

One may choose to participate in a clinical trial for many reasons. Volunteering often has multiple benefits, from advancing medical research to gaining access to cutting-edge medical care. However, deciding to enroll in a clinical trial is only one part of the process.

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When Worlds Collide: The Theory of Real-World Evidence Meets Reality

FDA Law Blog: Biosimilars

By Jeffrey N. Gibbs & Ana Loloei & Véronique Li, Senior Medical Device Regulation Expert — FDA has long touted the use of real-world evidence ( RWE ). Extolling RWE, FDA has said “RWE can be leveraged to bring new products to market, evaluate the safety and effectiveness of existing products for new uses, and assess the continued performance and safety of products once on the market.

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Clinical Data Like You´ve Never Seen It Before: Why Spotfire Is the Leading Tool for Clinical Analytics

Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

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Scientists work out the effects of exercise at the cellular level

Science Daily: Pharmacology News

The health benefits of exercise are well known but new research shows that the body's response to exercise is more complex and far-reaching than previously thought. In a study on rats, a team of scientists has found that physical activity causes many cellular and molecular changes in all 19 of the organs they studied in the animals.

Research 144
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Ajax, aiming for a better JAK drug, raises $95M to begin first tests

BioPharma Drive: Drug Pricing

Goldman Sachs and Eli Lilly are among those backing the startup, which claims its prospect could be more potent than the myelofibrosis therapies that have come to market in recent years.

Therapies 132
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Navigating Trust and Data in Healthcare Marketing

Perficient: Drug Development

In the ever-evolving landscape of healthcare, trust reigns supreme. As consumers increasingly rely on data to inform their decisions, the healthcare industry faces a pressing need to not only meet but exceed expectations. With disruptive forces emerging from various corners, healthcare organizations find themselves in a race to create personalized experiences that foster lasting engagement and trust.

Marketing 111
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Costs, Side Effects Drive Folks to Quit New Weight-Loss Meds

Drugs.com

THURSDAY, May 23, 2024 -- Three months after starting one of the new GLP-1 weight-loss drugs, more than a quarter of patients have already quit the medications, and by a year from first use more than a third have stopped, new research shows.Reasons.

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CDD Vault Update (May 2024)

Collaborative Drug

Hooray for curve overlays!! We are excited to announce a new round of features associated with our Curve Analytics Module. If you are not yet subscribed to Curve Analytics, please contact your CDD Vault account manager or the CDD Vault Support Team to discuss enabling these features in your Vault.

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AI headphones let wearer listen to a single person in a crowd, by looking at them just once

Science Daily: Pharmacology News

Engineers have developed an artificial intelligence system that lets someone wearing headphones look at a person speaking for three to five seconds to 'enroll' them. The system then plays just the enrolled speaker's voice in real time, even as the pair move around in noisy environments.

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Brain 'assembloids' mimic human blood-brain barrier

Science Daily: Pharmacology News

Major advance promises to accelerate the understanding and improved treatment of a wide range of brain disorders, including stroke, cerebral vascular disorders, brain cancer, Alzheimer's disease, Huntington disease, Parkinson's disease, and other neurodegenerative conditions.

Disease 141
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Stretchable e-skin could give robots human-level touch sensitivity

Science Daily: Pharmacology News

A stretchy electronic skin could equip robots and other devices with the same softness and touch sensitivity as human skin, opening up new possibilities to perform tasks that require a great deal of precision and control of force.

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Birth of universe's earliest galaxies observed for first time

Science Daily: Pharmacology News

Researchers have now seen the formation of three of the earliest galaxies in the universe, more than 13 billion years ago. The sensational discovery contributes important knowledge about the universe.

Research 140
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AI systems are already skilled at deceiving and manipulating humans

Science Daily: Pharmacology News

Many artificial intelligence (AI) systems have already learned how to deceive humans, even systems that have been trained to be helpful and honest. Researchers describe the risks of deception by AI systems and call for governments to develop strong regulations to address this issue as soon as possible.

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Scientists map networks regulating gene function in the human brain

Science Daily: Pharmacology News

A consortium of researchers has produced the largest and most advanced multidimensional maps of gene regulation networks in the brains of people with and without mental disorders. These maps detail the many regulatory elements that coordinate the brain's biological pathways and cellular functions. The research used postmortem brain tissue from over 2,500 donors to map gene regulation networks across different stages of brain development and multiple brain-related disorders.

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Significant new discovery in teleportation research -- Noise can improve the quality of quantum teleportation

Science Daily: Pharmacology News

Researchers succeeded in conducting an almost perfect quantum teleportation despite the presence of noise that usually disrupts the transfer of quantum state.

Research 140
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A fragment of human brain, mapped in exquisite detail

Science Daily: Pharmacology News

Researchers have created the largest synaptic-resolution, 3D reconstruction of a piece of human brain to date, showing in vivid detail each cell and its web of neural connections in a piece of human temporal cortex about half the size of a rice grain.

Research 139
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Did a magnetic field collapse trigger the emergence of animals?

Science Daily: Pharmacology News

Researchers uncovered compelling evidence that Earth's magnetic field was in a highly unusual state when the macroscopic animals of the Ediacaran Period -- 635 to 541 million years ago -- diversified and thrived. Their study raises the question of whether these fluctuations in Earth's ancient magnetic field led to shifts in oxygen levels that may have been crucial to the proliferation of life forms millions of years ago.

Research 140
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'Vigorous melting' at Antarctica's Thwaites 'Doomsday' Glacier

Science Daily: Pharmacology News

Glaciologists show evidence of warm ocean water intruding kilometers beneath grounded ice at Thwaites Glacier in West Antarctica. The findings suggest that existing climate models are underestimating the impact of ocean and ice interactions in future sea level rise projections.

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