ASPET

JULY 26, 2024

Cannabis and its products have been used for centuries for both medicinal and recreational purposes. The recent widespread legalization of cannabis has vastly expanded its use in the United States across all demographics except for adolescents. Meanwhile decades of research have advanced our knowledge of cannabis pharmacology and particularly of the endocannabinoid system with which the components of cannabis interact.

Research 189

Research Production 189

Science Daily: Pharmacology News

JULY 29, 2024

SARS-CoV-2, the virus responsible for COVID-19, is widespread among wildlife species, according to new research. The virus was detected in six common backyard species, and antibodies indicating prior exposure to the virus were found in five species, with rates of exposure ranging from 40 to 60 percent depending on the species.

Virus 145

Virus Research 145

Broad Institute

JULY 10, 2024

Prime editing efficiently corrects cystic fibrosis mutation in human lung cells By Allessandra DiCorato July 10, 2024 Breadcrumb Home Prime editing efficiently corrects cystic fibrosis mutation in human lung cells The approach targets the most common genetic cause of the disease and could enable a one-time treatment as effective as existing daily therapies.

Engineering 145

Engineering Packaging DNA Treatment 145

BioPharma Drive: Drug Pricing

JULY 30, 2024

The company is letting go of 150 staffers alongside a decision to officially terminate the high-profile program, which was acquired in 2016.

Therapies 136

Therapies 136

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

Treatment

Codon

JULY 14, 2024

Dr. Keith Neeves gives a history of blood transfusions and explains why it will be difficult to scale up the creation of synthetic blood for Issue 03 of Asimov Press. We are mostly blood. Of the 36 trillion cells in the human body, 32 trillion are blood cells. These blood cells synchronize the delivery of oxygen to every tissue in your body, fight pathogens, and heal wounds.

Production 133

Production Clinical Trials Trials Therapies 133

Antidote

JULY 30, 2024

In the latest installment of Talk of the Towne, we sat down with Melanie Paris, M.A., MPH, the Senior Director of Strategic Partnerships and Kidney Disease Education at the American Kidney Fund (AKF). In the discussion, we got her insights into the types of kidney disease, treatment disparities, and the importance of clinical research in the field. She also shared many valuable resources for individuals and their loved ones living with kidney disease, which are linked here.

Clinical Research 126

Clinical Research Disease Treatment Research 126

Science Daily: Pharmacology News

JULY 24, 2024

A study looks at the maximum possible sizes of dinosaurs, using the carnivore, Tyrannosaurus rex, as an example. Using computer modelling, experts produced estimates that T. Rex might have been 70% heavier than what the fossil evidence suggests.

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Broad Institute

JULY 8, 2024

Brain chimeroids offer window into relationships between genetics and exposures By Tom Ulrich July 8, 2024 Breadcrumb Home Brain chimeroids offer window into relationships between genetics and exposures New model system allows researchers to study the influence of genetic background on brain cells' responses to neurotoxins, disease mutations, and potential therapeutics By Alice McCarthy, Harvard University July 8, 2024 Credit: Arlotta laboratory A brain chimeroid Related people Paola Arlotta Rel

Trials 121

Trials Research Clinical Trials Laboratories 121

BioPharma Drive: Drug Pricing

JULY 2, 2024

The drug, which Lilly will sell as Kinsunla, carries a warning for the risk of a certain kind of imaging abnormality that can be serious in rare cases.

FDA 136

FDA Drugs 136

Drugs.com

JULY 23, 2024

TUESDAY, July 23, 2024 -- The boom in using GLP-1 drugs like Ozempic to treat obesity has resulted in a bust regarding the drugs’ original purpose, which was to treat type 2 diabetes, a new study finds. New prescriptions for these drugs have d.

Drugs 119

Drugs 119

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Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

Clinical Trials

Perficient: Drug Development

JULY 25, 2024

“Double, double toil and trouble,” is a line repeated by the witches in Macbeth as they lay out the ominous prophecies of greatness and dire consequences for the titular character. Macbeth’s ambition envisions a perfect ending though desperate actions and moral weakness ruin it. So too are the misguided actions in pursuit of perfection which can set expectations and pressure that lead to unwanted results.

Regulations 118

Regulations Compliance Production 118

Drug Target Review

JULY 23, 2024

What inspired you to pursue a career in STEM and can you tell us about how your career journey unfolded? An early introduction to STEM in the classroom sparked my passion for biology and I’m grateful for the exposure to different scientific concepts and contexts at a young age. I wanted to make a tangible impact on the world through biology and was drawn to the challenge of scientific discovery, which led me to pursue a career in the biotech/pharma industry.

Small Molecule 115

Small Molecule Targeted Protein Degradation Science Disease 115

Science Daily: Pharmacology News

JULY 25, 2024

A noninvasive colorectal cancer screening test that can be done at home could reduce the risk of colorectal cancer death by 33%, according to a new study.

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Antidote

JULY 11, 2024

When determining which clinical trial is the right fit , many factors must be considered. The site location, the number of required visits, and the length of the study are all important considerations, but before any of this, it is vital to consider the study's inclusion and exclusion criteria.

Clinical Trials 114

Clinical Trials Trials 114

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Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

Clinical Trials

BioPharma Drive: Drug Pricing

JULY 1, 2024

Study results are expected for a pair of closely watched obesity drugs, while key tests await for a high-priced AbbVie acquisition and one of 2023’s largest IPOs.

Clinical Trials 136

Clinical Trials Trials Drugs 136

Drugs.com

JULY 29, 2024

MONDAY, July 29, 2024 -- The U.S. Food and Drug Administration on Monday approved a new blood test that can spot colon cancer.In late May, an FDA advisory panel had voted 7-2 that the benefits outweigh the risks when using the Guardant Health's.

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FDA Approval FDA Drugs 119

Perficient: Drug Development

JULY 2, 2024

If you use ServiceNow as your knowledge management platform, you might want to make your knowledge articles searchable and accessible from Microsoft Search. Microsoft Search is a unified search experience that helps you find what you need across your organization, including files, sites, people, and more. By connecting your ServiceNow knowledge articles to Microsoft Search, you can enable your users to find and request them directly from the Microsoft 365 apps.

Production 118

Production 118

Codon

JULY 21, 2024

Xander Balwit offers concrete proposals for raising the welfare of animals used in biomedical research for our final article in Issue 03. We’ll be on a brief hiatus for the next few weeks as we prepare for the next Issue! If you’d like to write for us, send a pitch to editors@asimov.com. A hairless and obese rat grimaced at me from behind the glass—its taxidermied gaze fixed on something across the room.

Research 112

Research Engineering Disease Science 112

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Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

Clinical Trials

Science Daily: Pharmacology News

JULY 31, 2024

A new large study suggests incidence rates continued to rise in successively younger generations in 17 of the 34 cancer types, including breast, pancreatic, and gastric cancers. Mortality trends also increased in conjunction with the incidence of liver (female only), uterine corpus, gallbladder, testicular, and colorectal cancers.

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Broad Institute

JULY 19, 2024

An immune factor in the brain plays critical roles in neuron function and aging By Tom Ulrich July 19, 2024 Breadcrumb Home An immune factor in the brain plays critical roles in neuron function and aging Study highlights unexpected interactions between innate immune system and neurons, raises questions about additional roles for immune system in the brain with aging.

Protein Production 111

Protein Production Hospitals RNA Production 111

BioPharma Drive: Drug Pricing

JULY 18, 2024

The offering comes days after the publication of a paper showing what analysts said was early proof that “off-the-shelf” cell therapies can treat inflammatory diseases.

Therapies 131

Therapies Disease 131

Drugs.com

JULY 21, 2024

SUNDAY, July 21, 2024 -- As yet another batch of variants fuel a COVID surge this summer, one expert offers advice on how to navigate the threat.“We've seen a bit of a seasonal pattern emerge, where we've had an uptick in COVID in the summer and t.

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Antidote

JULY 15, 2024

Obesity, a condition that impacts 2 out of 5 adults in the United States , has become a significant health concern, both due to the impacts it has on individuals with the condition and the effect it can have on the overall medical system. It is estimated that obesity is responsible for nearly $1.73 billion in excess treatment costs annually, compounded by the fact that individuals with obesity are far more likely to have other conditions such as hypertension, diabetes, and osteoarthritis.

Treatment 111

Treatment 111

Quanticate

JULY 5, 2024

Good Clinical Practice (GCP) affects a variety of entities, including sponsors, contract research organisations (CROs), and investigator sites. It’s essential for maintaining ethical standards, high-quality outcomes and facilitating global standardisation, enabling multi-center and multinational studies, thereby streamlining the development and approval process for new medical treatments, and maintaining public trust in clinical research.

Clinical Research 111

Clinical Research Drug Development Treatment Research 111

Science Daily: Pharmacology News

JULY 17, 2024

Have you ever wondered how insects are able to go so far beyond their home and still find their way? The answer to this question is not only relevant to biology but also to making the AI for tiny, autonomous robots. Drone-researchers felt inspired by biological findings on how ants visually recognize their environment and combine it with counting their steps in order to get safely back home.

Research 143

Research 143

Drug Patent Watch

JULY 11, 2024

The value proposition of Contract Development and Manufacturing Organizations (CDMOs) has become increasingly crucial in the pharmaceutical industry.

Pharmaceuticals 111

Pharmaceuticals 111

BioPharma Drive: Drug Pricing

JULY 15, 2024

Updated results show the biotech's RAS inhibitor shrank pancreatic tumors in 20% to 25% of study participants, but with high rates of side effects like rash and nausea.

Trials 130

Trials Drugs 130

Drugs.com

JULY 2, 2024

TUESDAY, July 2, 2024 -- Benzodiazepines do not appear to increase dementia risk, but could have subtle long-term effects on brain structure, a new study reports.Researchers found no link between use of the sedative drug and a higher risk of.

Drugs 119

Drugs 119

Perficient: Drug Development

JULY 3, 2024

In today’s digital landscape, delivering exceptional customer experiences is paramount. Salesforce OmniStudio empowers you to create engaging, personalized, and brand-consistent interactions across all touchpoints. This blog post delves into OmniStudio, exploring its capabilities, benefits, and how you can leverage it to elevate your customer journeys.

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International Marketing 111

addgene Blog

JULY 9, 2024

What's new in Addgene's ready-to-use viral vectors repository? Quite a bit! In this post, we'll share the 20 additions we've made to our viral vectors repository since March.

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Science Daily: Pharmacology News

JULY 25, 2024

An experimental drug originally developed to treat cancer may help clear HIV from infected cells in the brain, according to a new study. By targeting infected cells in the brain, drug may clear virus from hidden areas that have been a major challenge in HIV treatment.

Virus 142

Virus Drugs Treatment 142

Drug Patent Watch

JULY 6, 2024

China is emerging as a global frontrunner in patenting artificial intelligence (AI) technologies for drug discovery, particularly in the field […] Source

Pharmaceuticals 108

Pharmaceuticals Drugs 108

BioPharma Drive: Drug Pricing

JULY 11, 2024

Far behind companies like Novo and Eli Lilly, Pfizer hopes the version of the drug, danuglipron, that it’s chosen to advance can break into the ultra-lucrative market for weight-loss medicines.

Marketing 128

Marketing Drugs 128