Drug Discovery World
JULY 11, 2024
Evotec and Pfizer have entered into a multi-year research collaboration, initially focused on early discovery research for metabolic and infectious diseases. The research will be carried out at Evotec’s sites in France, including Campus Curie in Toulouse with capabilities spanning high throughput screening, in vitro and in vivo biology, proteomics and metabolomics.
Broad Institute
JULY 10, 2024
Prime editing efficiently corrects cystic fibrosis mutation in human lung cells By Allessandra DiCorato July 10, 2024 Breadcrumb Home Prime editing efficiently corrects cystic fibrosis mutation in human lung cells The approach targets the most common genetic cause of the disease and could enable a one-time treatment as effective as existing daily therapies.
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Science Daily: Pharmacology News
JULY 31, 2024
A new large study suggests incidence rates continued to rise in successively younger generations in 17 of the 34 cancer types, including breast, pancreatic, and gastric cancers. Mortality trends also increased in conjunction with the incidence of liver (female only), uterine corpus, gallbladder, testicular, and colorectal cancers.
BioPharma Drive: Drug Pricing
JULY 18, 2024
The offering comes days after the publication of a paper showing what analysts said was early proof that “off-the-shelf” cell therapies can treat inflammatory diseases.
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Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.
Antidote
JULY 30, 2024
In the latest installment of Talk of the Towne, we sat down with Melanie Paris, M.A., MPH, the Senior Director of Strategic Partnerships and Kidney Disease Education at the American Kidney Fund (AKF). In the discussion, we got her insights into the types of kidney disease, treatment disparities, and the importance of clinical research in the field. She also shared many valuable resources for individuals and their loved ones living with kidney disease, which are linked here.
Drugs.com
JULY 23, 2024
TUESDAY, July 23, 2024 -- The boom in using GLP-1 drugs like Ozempic to treat obesity has resulted in a bust regarding the drugs’ original purpose, which was to treat type 2 diabetes, a new study finds. New prescriptions for these drugs have d.
Drug Discovery Digest brings together the best content for drug research and development professionals from the widest variety of industry thought leaders.
Perficient: Drug Development
JULY 25, 2024
“Double, double toil and trouble,” is a line repeated by the witches in Macbeth as they lay out the ominous prophecies of greatness and dire consequences for the titular character. Macbeth’s ambition envisions a perfect ending though desperate actions and moral weakness ruin it. So too are the misguided actions in pursuit of perfection which can set expectations and pressure that lead to unwanted results.
Science Daily: Pharmacology News
JULY 29, 2024
SARS-CoV-2, the virus responsible for COVID-19, is widespread among wildlife species, according to new research. The virus was detected in six common backyard species, and antibodies indicating prior exposure to the virus were found in five species, with rates of exposure ranging from 40 to 60 percent depending on the species.
BioPharma Drive: Drug Pricing
JULY 1, 2024
Study results are expected for a pair of closely watched obesity drugs, while key tests await for a high-priced AbbVie acquisition and one of 2023’s largest IPOs.
Antidote
JULY 11, 2024
When determining which clinical trial is the right fit , many factors must be considered. The site location, the number of required visits, and the length of the study are all important considerations, but before any of this, it is vital to consider the study's inclusion and exclusion criteria.
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Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.
Drugs.com
JULY 25, 2024
THURSDAY, July 25, 2024 -- The bird flu is now jumping between species of mammals, a step that draws the virus closer to hopping into human beings, a new study warns.Researchers have tracked transmission of avian influenza between dairy cows in.
Drug Discovery World
JULY 5, 2024
Newron Pharmaceuticals has reported new findings of mechanism of action that indicate its drug candidate evenamide could be uniquely effective in patients with treatment resistant schizophrenia (TRS). The drug’s unique mechanism of action targets the core abnormalities in patients with schizophrenia and reduces hippocampal dopaminergic activity, improving symptoms of psychosis, social interactions and cognition.
Perficient: Drug Development
JULY 2, 2024
If you use ServiceNow as your knowledge management platform, you might want to make your knowledge articles searchable and accessible from Microsoft Search. Microsoft Search is a unified search experience that helps you find what you need across your organization, including files, sites, people, and more. By connecting your ServiceNow knowledge articles to Microsoft Search, you can enable your users to find and request them directly from the Microsoft 365 apps.
Science Daily: Pharmacology News
JULY 3, 2024
Scientists have created an anode-free sodium solid-state battery. This brings the reality of inexpensive, fast-charging, high-capacity batteries for electric vehicles and grid storage closer than ever.
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Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic
BioPharma Drive: Drug Pricing
JULY 15, 2024
Updated results show the biotech's RAS inhibitor shrank pancreatic tumors in 20% to 25% of study participants, but with high rates of side effects like rash and nausea.
Broad Institute
JULY 19, 2024
An immune factor in the brain plays critical roles in neuron function and aging By Tom Ulrich July 19, 2024 Breadcrumb Home An immune factor in the brain plays critical roles in neuron function and aging Study highlights unexpected interactions between innate immune system and neurons, raises questions about additional roles for immune system in the brain with aging.
Drugs.com
JULY 19, 2024
FRIDAY, July 19, 2024 -- A German man has become the seventh person to apparently be cured of HIV, researchers report.The 60-year-old man, referred to as the “next Berlin Patient,” was treated with a stem cell transplant in October 2015 for acute my.
Antidote
JULY 15, 2024
Obesity, a condition that impacts 2 out of 5 adults in the United States , has become a significant health concern, both due to the impacts it has on individuals with the condition and the effect it can have on the overall medical system. It is estimated that obesity is responsible for nearly $1.73 billion in excess treatment costs annually, compounded by the fact that individuals with obesity are far more likely to have other conditions such as hypertension, diabetes, and osteoarthritis.
Quanticate
JULY 5, 2024
Good Clinical Practice (GCP) affects a variety of entities, including sponsors, contract research organisations (CROs), and investigator sites. It’s essential for maintaining ethical standards, high-quality outcomes and facilitating global standardisation, enabling multi-center and multinational studies, thereby streamlining the development and approval process for new medical treatments, and maintaining public trust in clinical research.
Science Daily: Pharmacology News
JULY 1, 2024
Computer scientists have invented a camera mechanism that improves how robots see and react to the world around them. Inspired by how the human eye works, their innovative camera system mimics the tiny involuntary movements used by the eye to maintain clear and stable vision over time.
BioPharma Drive: Drug Pricing
JULY 11, 2024
Far behind companies like Novo and Eli Lilly, Pfizer hopes the version of the drug, danuglipron, that it’s chosen to advance can break into the ultra-lucrative market for weight-loss medicines.
Perficient: Drug Development
JULY 3, 2024
In today’s digital landscape, delivering exceptional customer experiences is paramount. Salesforce OmniStudio empowers you to create engaging, personalized, and brand-consistent interactions across all touchpoints. This blog post delves into OmniStudio, exploring its capabilities, benefits, and how you can leverage it to elevate your customer journeys.
Drugs.com
JULY 18, 2024
THURSDAY, July 18, 2024 -- A new monoclonal antibody treatment called Kesimpta (ofatumumab) appears to improve on an older drug in pushing multiple sclerosis (MS) into remission, a new trial shows.Funded by Kesimpta's maker, Novartis, the trial.
Drug Patent Watch
JULY 30, 2024
The Power of Patent Licensing: Unlocking Innovation and Access to Medicines Patent licensing agreements have become a crucial tool in the pharmaceutical industry, allowing companies to collaborate and…
FDA Law Blog: Biosimilars
JULY 23, 2024
By Adrienne R. Lenz, Principal Medical Device Regulation Expert — For several years, FDA has requested that sponsors of drug or biologic led combination products identify essential performance requirements (EPRs) related to the device constituent in their applications. EPRs were usually requested in the context of design controls, although 21 C.F.R. § 820.30 does not use this term.
Science Daily: Pharmacology News
JULY 17, 2024
Have you ever wondered how insects are able to go so far beyond their home and still find their way? The answer to this question is not only relevant to biology but also to making the AI for tiny, autonomous robots. Drone-researchers felt inspired by biological findings on how ants visually recognize their environment and combine it with counting their steps in order to get safely back home.
BioPharma Drive: Drug Pricing
JULY 2, 2024
The company claimed Phase 2 study results prove the therapy’s promise treating myasthenia gravis. But shares lost more than a quarter of their value amid questions about the data.
Quanticate
JULY 22, 2024
Throughout the conduct of a clinical trial, ensuring patient safety and maintaining the integrity of the study are vital. This is where, Data Monitoring Committees (DMC) are used to support patient safety and integrity.
Drugs.com
JULY 19, 2024
FRIDAY, July 19, 2024 -- It's long been known that popping the antibiotic doxycycline within 72 hours of a risky sexual encounter can greatly reduce a person's risk for a sexually transmitted infection (STI). In fact, the U.S. Centers for Disease.
Fierce BioTech
JULY 19, 2024
InMed’s INM-901 Demonstrates Potential as a Multi-factorial Approach to Treating Alzheimer’s Disease jpiatt Fri, 07/19/2024 - 09:56
Drug Patent Watch
JULY 21, 2024
The Patent Trial and Appeal Board (PTAB) is a crucial component of the United States Patent and Trademark Office (USPTO), established in 2012 by the Leahy-Smith America Invents Act (AIA).
Science Daily: Pharmacology News
JULY 4, 2024
Researchers have discovered several rare types of helper T cells that are associated with immune disorders such as multiple sclerosis, rheumatoid arthritis, and even asthma. The discoveries were made possible by a newly developed technology they call ReapTEC. The new T cell atlas is publicly available and should help in the development of new drug therapies for immune-mediated diseases.
BioPharma Drive: Drug Pricing
JULY 30, 2024
The company is letting go of 150 staffers alongside a decision to officially terminate the high-profile program, which was acquired in 2016.
Perficient: Drug Development
JULY 18, 2024
Perficient’s Giving Employee Resource Group (ERG) recently introduced the Perficient Gives Global Grants Program , which gives colleagues the opportunity to nominate charitable organizations from around the world to receive a $5,000 donation from Perficient. After carefully evaluating each nomination, Perficient’s Giving ERG leadership team selected the first five organizations to receive a donation.
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