November, 2021

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Quantum Computing in drug discovery receives £6.85 million boost

Drug Discovery Today

Innovate UK grant awarded for the development of quantum computing in cancer treatment

Treatment 113
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Consolidation and Preferred Pharmacy Networks in 2022’s Medicare Part D Plans: Cigna, CVS Health, Humana, UnitedHealthcare, WellCare, and More

Drug Channels

Open enrollment is under way for the 2022 Medicare Part D plans. Our exclusive analysis of Center for Medicare & Medicaid Services’ (CMS) data reveals that preferred cost sharing pharmacy networks will maintain their dominance as an established component of Part D benefit design. For 2022: 98% of stand-alone Medicare Part D prescription drug plans (PDP) will have a preferred network. 66% of Medicare Advantage prescription drug (MA-PD) plans will have a preferred network.

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Which pharmaceutical companies have the most SPCs in Slovakia?

Drug Patent Watch

This chart shows the pharmaceutical companies with the most supplementary protection certificates (SPCs) in Slovakia. SPCs are used in European Union and select others to encourage pharmaceutical innovation by compensating…. The post Which pharmaceutical companies have the most SPCs in Slovakia? appeared first on DrugPatentWatch - Make Better Decisions.

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Amgen Named To Dow Jones Sustainability World Index For Eighth Consecutive Year

The Pharma Data

Amgen Ranks in Top 10% of Biotechnology Companies Worldwide, Earning Top Scores in Business Ethics, Philanthropy, and Environmental Reporting. Amgen today announced that it has been named to the Dow Jones Sustainability World Index for the eighth consecutive year, reflecting the company’s enduring commitment to environmental, social, and governance (ESG) issues.

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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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Covid 19 Booster Dose – Should we consider it?

ProRelix Research

Covid 19 Booster Dose – Should we consider it? The idea of booster doses for Covid-19 vaccinations is gaining traction around the world, but India remains a skeptic. Various countries, […]. The post Covid 19 Booster Dose – Should we consider it? appeared first on ProRelix Research.

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Early Data Suggest Pfizer Pill May Prevent Severe COVID-19

NIH Director's Blog: Drug Development

Credit: Fizkes/Shutterstock Over the course of this pandemic, significant progress has been made in treating COVID-19 and helping to save lives. That progress includes the development of life-preserving monoclonal antibody infusions and repurposing existing drugs , to which NIH’s Accelerating COVID-19 Therapeutic Interventions and Vaccines (ACTIV ) public-private partnership has made a major contribution.

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CVS, Walgreens, Walmart, and Supermarkets Keep Position in 2022 Part D Preferred Networks—With a Little Help from 340B

Drug Channels

In Consolidation and Preferred Pharmacy Networks in 2022’s Medicare Part D Plans , I highlighted how those networks have hijacked the world of stand-alone Medicare Part D prescription drug plans (PDP) and become a major presence in Medicare Advantage prescription drug (MA-PD) plans. Today, I examine the largest retail chains’ participation in the 21 major 2022 Part D preferred networks that the eight largest plan sponsors will offer.

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New patent for Alkermes Inc drug ARISTADA INITIO KIT

Drug Patent Watch

Annual Drug Patent Expirations for ARISTADA+INITIO+KIT Aristada Initio Kit is a drug marketed by Alkermes Inc and is included in one NDA. It is available from one supplier. There are…. The post New patent for Alkermes Inc drug ARISTADA INITIO KIT appeared first on DrugPatentWatch - Make Better Decisions.

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Bristol Myers Squibb’s Applications for Deucravacitinib for the Treatment of Moderate to Severe Plaque Psoriasis Accepted by U.S. Food and Drug Administration and Validated by European Medicines Agency

The Pharma Data

Applications supported by positive results from the pivotal Phase 3 POETYK-PSO clinical trial program demonstrating superior efficacy of deucravacitinib over Otezla ® (apremilast) and placebo in treating adults with moderate to severe plaque psoriasis. U.S. Food and Drug Administration assigned a target action date of September 10, 2022; European Medicines Agency validation confirms the submission is complete and begins the centralized review process.

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Is drug R&D more like poker or chess?

Plenge Gen

[Disclaimers: I am an employee of Bristol Myers Squibb. The views expressed here are my own. Also, I am not a particularly good poker or chess player. It is one reason I am a popular invited guest to poker nights with friends.] I posted on poll on Twitter to ask the question is drug discovery more like poker or chess. There were over 300 responses, with the results split nearly equally (54% poker, 46% chess).

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How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

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Leveraging Targeted Mouse I/O RNA-Seq Panels to Improve the Translatability of Immuno-Oncology Studies

Crown Bioscience

In this post, we explore how a targeted RNA-Sequencing (RNA-Seq) panel can be incorporated into preclinical drug development to evaluate the impact of immune effectors in mediating anti-tumor immunity of novel immuno-oncology (I/O) agents. A case study highlights how RNA-Seq panels can complement traditional protein-based assays to gain a truly comprehensive picture of novel immunotherapies.

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How to make the challenge of mRNA delivery easy

Tebu Bio: Drug Discovery

Many researchers are facing the challenges of mRNA delivery, through the body into the cytoplasm of cells. In this post, we invite you to discover some useful and efficient solutions to improve and control all the steps of your mRNA delivery project.

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Pathway or Perish: The Two-Pronged Hurdle to Ensuring Access in Oncology

Drug Channels

Today’s guest post comes from Carolyn Zele, Senior Manager of Solution Enablement at MMIT. Carolyn describes how oncology pathways were developed to help standardize treatment and ensure quality care. She argues, however, that these pathways often shut manufacturers out of the market. Click here to learn more about MMIT's Pulse Analytics solution , which provides insight into payer- and pathway-driven barriers to access.

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Which pharmaceutical drugs have the most drug patents in Denmark?

Drug Patent Watch

This chart shows the drugs with the most patents in Denmark. Patents must be filed in each country (or, in some cases regional patent office) where patent protection is desired.…. The post Which pharmaceutical drugs have the most drug patents in Denmark? appeared first on DrugPatentWatch - Make Better Decisions.

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Deliver Fast, Flexible Clinical Trial Insights with Spotfire

Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

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WHO update on Omicron

The Pharma Data

On 26 November 2021, WHO designated the variant B.1.1.529 a variant of concern, named Omicron, on the advice of WHO’s Technical Advisory Group on Virus Evolution (TAG-VE). This decision was based on the evidence presented to the TAG-VE that Omicron has several mutations that may have an impact on how it behaves, for example, on how easily it spreads or the severity of illness it causes.

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Tips for Living with Plaque Psoriasis

Olympian Clinical Research

If you’ve been suffering from plaque psoriasis for a while, you may be frustrated and eager for something that can help. Living with plaque psoriasis can be difficult, and you might not know where to turn or who can help. Fortunately, there are tips and treatment options available to you to help lessen your symptoms. Symptoms of Plaque Psoriasis.

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Use of Social Media and Mobile Devices – Study Participants Recruitment

ProRelix Research

Use of Social Media and Mobile Devices – Study Participants Recruitment There has been a significant change in the clinical trial and advertising industries over the last five years that […]. The post Use of Social Media and Mobile Devices – Study Participants Recruitment appeared first on ProRelix Research.

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OpenEye Scientific’s OMEGA Generates 3D Molecular Conformers for Drug Design 30X Faster with NVIDIA

Nvidia Developer: Drug Discovery

Computational molecular design involves compute-intense calculations that require exceptional processing power. Whether working in pharmaceuticals, Computational molecular design involves compute-intense calculations that require exceptional processing power. Whether working in pharmaceuticals, biotechnology, agrochemicals, or the fragrance industry, researchers are oftentimes dealing with datasets that encompass millions to billions of compounds.

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Clinical Data Like You´ve Never Seen It Before: Why Spotfire Is the Leading Tool for Clinical Analytics

Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

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CVS Pharmacy Downsizes: 10 Industry Trends Driving the Retail Shakeout

Drug Channels

ICYMI, CVS Health recently announced that it will close about 900 of its retail pharmacies. This downsizing complements the company’s shift toward its healthcare delivery future. This long-overdue move highlights the retail industry’s fundamental economic headwinds. The pharmacy shakeout is accelerating, as smaller competitors exit and larger companies reduce store count.

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Most prolific drug patent challengers

Drug Patent Watch

This chart shows the generic pharmaceutical companies that had the most successful drug patent challenges from 2016 to 2021. Companies that successfully challenge patents on branded drugs are granted six…. The post Most prolific drug patent challengers appeared first on DrugPatentWatch - Make Better Decisions.

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Johnson & Johnson to Evaluate Its COVID-19 Vaccine Against New Omicron COVID-19 Variant

The Pharma Data

Since the emergence of the COVID-19 epidemic, Johnson & Johnson (the Company) has been nearly covering recently arising COVID-19 variants. In collaboration with academic groups in South Africa and around the world, the Company has been assessing the effectiveness of its COVID-19 vaccine across variants, including now the new and fleetly spreading Omicron variant.

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How to Overcome Social Anxiety

Olympian Clinical Research

Overcoming social anxiety is a process that takes time and commitment, often beginning in the early ages of childhood and adolescence. Social Anxiety Disorder (SAD) affects 15 million American adults and is prevalent in an estimated 9.1% of adolescents between the ages of 13 and 18. Most children experience an onset of SAD between the ages of eight and 15, and it can be triggered by a traumatic experience or emerge from a natural tendency of shyness. .

Doctors 52
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Picking the Highest Scoring Molecule(s) From Each Cluster

Practical Cheminformatics

Here's a quick post based on a conversation with a friend who wanted to be able to cluster a set of docked molecules based on fingerprints and select the highest scoring molecule(s) from each cluster. As usual, Pandas made this super easy. The code for this example can be run on Colab and is also available as a Gist.

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Latest news on drug repurposing in oncology #12

The Anticancer Fund

26 November 2021 Language EN Drug repurposing is a strategy for identifying new uses for approved drugs, outside the scope of the original indication. It is one of the focus areas of the Anticancer Fund. Below, we have listed recent findings about the repurposing of generic drugs in oncology. Our intention is to help bring these findings to the attention of the broader cancer research community.

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Why PBMs and Payers Are Embracing Insulin Biosimilars with Higher Prices—And What That Means for Humira

Drug Channels

The Food & Drug Administration (FDA) recently approved the first interchangeable biosimilar insulin product: the insulin glargine-yfgn injection from Viatris. Read the FDA’s press release. Alas, I’m sad to report that the warped incentives baked into the U.S. drug channel will limit the impact of this impressive breakthrough. Viatris is being forced to launch both a high-priced and a low-priced version of the biosimilar.

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Which pharmaceutical companies have the most SPCs in Lithuania?

Drug Patent Watch

This chart shows the pharmaceutical companies with the most supplementary protection certificates (SPCs) in Lithuania. SPCs are used in European Union and select others to encourage pharmaceutical innovation by compensating…. The post Which pharmaceutical companies have the most SPCs in Lithuania? appeared first on DrugPatentWatch - Make Better Decisions.

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FDA Approves New Imaging Drug to Help Identify Ovarian Cancer Lesions

The Pharma Data

The U.S. Food and Drug Administration today approved Cytalux (pafolacianine), an imaging drug intended to assist surgeons in identifying ovarian cancer lesions. The drug is designed to improve the ability to locate additional ovarian cancerous tissue that is normally difficult to detect during surgery. Cytalux is indicated for use in adult patients with ovarian cancer to help identify cancerous lesions during surgery.

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The Once and Future FDA Commissioner

Eye on FDA

In what has been a glacially paced nomination process, the Biden Administration announced on November 12 that it would, in fact, be nominating Dr. Robert Califf to return to his role as FDA Commissioner. Acting Comissioner Janet Woodcock indicated in a tweet that she would be remaining in the role of Acting Commissioner during the confirmation process.

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The World's First Cloud Lab, HTE, Lab Automation Virtual Conference - Event Recap

The Strateos Blog: Drug Discovery

Between October 11-13th, Strateos was a proud participant at the 20/15 Visioneers Cloud Lab, HTE, Lab Automation Virtual Conference alongside other thought leaders in the space such as PerkinElmer, Dotmatics and Gingko Bioworks. The theme of the conference was how laboratory automation, HTE, and cloud labs are enabling model-quality data generation to drive better, more efficient experimentation to accelerate scientific discoveries.

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Which pharmaceutical drugs have the most drug patents in Denmark?

Drug Patent Watch

This chart shows the drugs with the most patents in Denmark. Patents must be filed in each country (or, in some cases regional patent office) where patent protection is desired.…. The post Which pharmaceutical drugs have the most drug patents in Denmark? appeared first on DrugPatentWatch - Make Better Decisions.

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New patent expiration for Novartis drug AMTURNIDE

Drug Patent Watch

Annual Drug Patent Expirations for AMTURNIDE Amturnide is a drug marketed by Novartis and is included in one NDA. There are two patents protecting this drug. This drug has one…. The post New patent expiration for Novartis drug AMTURNIDE appeared first on DrugPatentWatch - Make Better Decisions.

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New patent expiration for Glaxo Grp drug FLOVENT HFA

Drug Patent Watch

Annual Drug Patent Expirations for FLOVENT+HFA Flovent Hfa is a drug marketed by Glaxo Grp Ltd and is included in one NDA. It is available from four suppliers. There are…. The post New patent expiration for Glaxo Grp drug FLOVENT HFA appeared first on DrugPatentWatch - Make Better Decisions.

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Which pharmaceutical companies have the most suppository dosed drugs?

Drug Patent Watch

This chart shows the pharmaceutical companies with the most suppository dosed drugs. For a different perspective, see the most popular dosage types. The companies with the most suppository dosed drugs…. The post Which pharmaceutical companies have the most suppository dosed drugs? appeared first on DrugPatentWatch - Make Better Decisions.