Sat.Sep 23, 2023 - Fri.Sep 29, 2023

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FDA Adds Warning to Ozempic Label About Risk for Blocked Intestines

Drugs.com

WEDNESDAY, Sept. 27, 2023 -- Ozempic, a type 2 diabetes drug that has increasingly been used to help with weight loss, will now be labeled as having the potential to block intestines. The U.S. Food and Drug Administration recently made the label.

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Why are killer whales harassing and killing porpoises without eating them?

Science Daily: Pharmacology News

For decades, fish-eating killer whales in the Pacific Northwest have been observed harassing and even killing porpoises without consuming them —- a perplexing behavior that has long intrigued scientists.

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FDA staff hold ‘major concerns’ with Brainstorm ALS therapy, documents show

BioPharma Drive: Drug Pricing

Agency scientists flagged numerous issues with Brainstorm’s stem cell treatment ahead of a high-profile Wednesday meeting of expert FDA advisers.

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CDD Vault Update (September 2023)

Collaborative Drug

Fun with Ketcher New keyboard shortcuts have been added to the structure editor. Cycle through menu options and easily lookup abbreviations while still being able to assign the same atom to multiple locations.

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Bridging Innovation & Patient Care: The Growing Role of AI

Speaker: Simran Kaur, Co-founder & CEO at Tattva.Health

AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!

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Just 23% of U.S. Adults 'Definitely' Plan to Get New COVID Shot

Drugs.com

WEDNESDAY, Sept. 27, 2023 -- Just 23% of American adults say they 'definitely' will get the new COVID-19 vaccine, while another 23% say they will 'probably' get it, according to a new poll, which also finds interest in the shot falls along partisan.

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PTC to lay off more staff following drug setback in Europe

BioPharma Drive: Drug Pricing

The biotech is expanding cuts it announced a few months ago after the EMA decided against renewing a conditional clearance for its drug Translarna.

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CDD Attending Biotech Networks Scientific Speed Networking Event: DC Area OCT 11 2023

Collaborative Drug

Biotech Networks Scientific Speed Networking: DC Area October 11th 2023

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New Antibiotic, Ceftobiprole, Could Help Fight Resistant Staph Infections

Drugs.com

THURSDAY, Sept. 28, 2023 -- New research shows that an antibiotic effective for bacterial pneumonia also appears to fight treatment-resistant staph infections. The drug is ceftobiprole. It appeared successful in fighting methicillin-resistant staph.

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New study definitively confirms Gulf Stream weakening, understanding the changes could help predict future trends in extreme events

Science Daily: Pharmacology News

The Gulf Stream transport of water through the Florida Strait has slowed by 4% over the past four decades, with a 99% certainty that this weakening is more than expected from random chance, according to a new study.

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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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Roche bets on Ionis RNA medicines with neuroscience deal

BioPharma Drive: Drug Pricing

The Swiss drugmaker is restocking its pipeline by buying into preclinical Ionis medicines for Alzheimer’s and Huntington’s diseases.

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Recorded Webinar: Manage Protocol/Assay Definitions in CDD Vault

Collaborative Drug

Recorded Webinar: Manage Protocol/Assay Definitions in CDD Vault Dive deep into the latest advancements for managing biological assay data within the CDD Vault.

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Unsafe Neighborhoods Have Higher Levels of Child Abuse

Drugs.com

MONDAY, Sept. 25, 2023 -- Having safer neighborhoods, where families feel less stress, can help prevent child abuse, according to new research that supports this long-suspected theory. When parents feel higher levels of stress or hopelessness about.

Research 290
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New study provides evidence for more effective brain-based treatment of chronic back pain

Science Daily: Pharmacology News

A new study may provide key answers to how to help people experiencing chronic back pain. The study examined the critical connection between the brain and pain for treating chronic pain. Specifically, they looked at the importance of pain attributions, which are people's beliefs about the underlying causes of their pain, to reduce chronic back pain severity.

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How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

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ProQR sale of eye drugs comes undone over employment contracts

BioPharma Drive: Drug Pricing

Laboratoires Théa terminated its planned purchase of ProQR’s sepofarsen after certain ProQR personnel opted against working for the French company.

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Scientists reveal cellular changes unique to early Alzheimer’s disease

Broad Institute

Scientists reveal cellular changes unique to early Alzheimer’s disease By Allessandra DiCorato September 28, 2023 Breadcrumb Home Scientists reveal cellular changes unique to early Alzheimer’s disease A study of brain tissue from living adults provides a rare look into the earliest stages of the neurodegenerative disease and highlights cell types involved in plaque production.

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Is the First Cure for Advanced Rabies Near?

Drugs.com

THURSDAY, Sept. 28, 2023 -- Rabies virus is incurable and almost always fatal once it has invaded the central nervous system, with the victim doomed to suffer a horrible death. But researchers now think they’ve found an effective and simple.

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Down goes antimatter! Gravity's effect on matter's elusive twin is revealed

Science Daily: Pharmacology News

For the first time, in a unique laboratory experiment at CERN, researchers have observed individual atoms of antihydrogen fall under the effects of gravity. In confirming antimatter and regular matter are gravitationally attracted, the finding rules out gravitational repulsion as the reason why antimatter is largely missing from the observable universe.

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Deliver Fast, Flexible Clinical Trial Insights with Spotfire

Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

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BrainStorm’s ALS therapy not effective, FDA panel finds

BioPharma Drive: Drug Pricing

Expert advisers to the agency voted 17-1 that Brainstorm's clinical trial data did not show the company's stem cell treatment was effective for treating ALS.

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New optogenetic tools for cytoskeleton and membrane control

addgene Blog

Optogenetics gives you the power to control cells or organisms with the flip of a switch. You may be familiar with popular light-sensitive ion channels used to control activities like neuronal signaling — think of a mouse with an LED brain implant or a worm wiggling back and forth under blue light — but there’s a lot more to optogenetics than neuronal activity.

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FDA Panel Says No to Experimental ALS Drug, NurOwn

Drugs.com

THURSDAY, Sept. 28, 2023 – An advisory panel to the U.S. Food and Drug Administration on Wednesday voted resoundingly against recommending, NurOwn, a stem cell-based experimental treatment for ALS. Although the FDA isn't bound by the votes of.

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Did life exist on Mars? Other planets? With AI's help, we may know soon

Science Daily: Pharmacology News

Scientists have discovered a simple and reliable test for signs of past or present life on other planets -- 'the holy grail of astrobiology.' Researchers report that, with 90% accuracy, their artificial intelligence-based method distinguished modern and ancient biological samples from those of abiotic origin.

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Clinical Data Like You´ve Never Seen It Before: Why Spotfire Is the Leading Tool for Clinical Analytics

Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

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Intercept, after biotech rollercoaster ride, agrees to buyout by Alfasigma

BioPharma Drive: Drug Pricing

Once valued at more than $7 billion, the liver drug company couldn’t secure a long-sought FDA approval in NASH and last month said it would abandon that research.

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Recent Highlights in Covalent Drug Discovery

Drug Hunter

In Wednesday’s Flash Talk webinar, we covered recent highlights in covalent drug discovery, with lots of great questions from the audience. The webinar and recording are available below to everyone thanks to our sponsor, Revvity Signals, and the slides are available for download to Premium members at the bottom. The talk covered: Covalent drugs that break the toxicity stigma Case studies from notable recent covalent molecules Covalent drugs to watch Some of the highlights mentioned in the talk i

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Common Plastics Chemical Tied to Higher Odds for Postpartum Depression

Drugs.com

TUESDAY, Sept. 26, 2023 -- Moms with higher prenatal levels of plastics chemicals known as phthalates may face a slightly increased risk of postpartum depression, according to a new study.

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Wild Asian elephants display unique puzzle solving skills

Science Daily: Pharmacology News

A new study has documented the abilities of individual wild Asian elephants to access food by solving puzzles that unlocked storage boxes. It is the first research study to show that individual wild elephants have different willingness and abilities to problem solve in order to get food.

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Structure boosted by early data for experimental obesity drug

BioPharma Drive: Drug Pricing

Shares in the biotech surged on Phase 1 trial results for an oral GLP-1 drug Structure is developing, reflecting investor enthusiasm for the weight loss medicines.

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