Science Daily: Pharmacology News
JANUARY 26, 2024
Compared to robots, human bodies are flexible, capable of fine movements, and can convert energy efficiently into movement. Drawing inspiration from human gait, researchers from Japan crafted a two-legged biohybrid robot by combining muscle tissues and artificial materials. This method allows the robot to walk and pivot.
Drugs.com
JANUARY 24, 2024
WEDNESDAY, Jan. 24, 2024 (Healthday News) -- The U.S. Food and Drug Administration has told drugmakers to add a boxed warning to a type of cancer treatment called CAR-T therapy, saying the treatment itself may sometimes cause a secondary.
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BioPharma Drive: Drug Pricing
JANUARY 22, 2024
New details of the proposed acquisitions show there were multiple interested buyers, which, according to some analysts, could set the stage for more dealmaking.
Collaborative Drug
JANUARY 22, 2024
Import File Parser We're excited to announce a significant update to the CDD Vault Import Data wizard. This update introduces a flexible parser to accommodate a wider range of data file formats beyond the traditional tabular ("long and skinny") layout. Now, you can easily import data files organized in various formats, including those resembling a Plate layout.
Speaker: Simran Kaur, Co-founder & CEO at Tattva.Health
AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!
Science Daily: Pharmacology News
JANUARY 25, 2024
An international group of leading scientists call for an urgent change in the governance of urban expansion as the world's cities continue to grow at unprecedented rates.
Drug Discovery Digest brings together the best content for drug research and development professionals from the widest variety of industry thought leaders.
BioPharma Drive: Drug Pricing
JANUARY 23, 2024
A black box warning for secondary T cell malignancies should be added to the labeling of all six approved CAR-T therapies, the agency said.
Collaborative Drug
JANUARY 24, 2024
Date: February 3rd to 7th 2024 Location: Boston Convention and Exhibition Center Boston, MA, Collaborative Drug Discovery (CDD) is excited to announce our participation in SLAS 2024 International Conference & Exhibition , from February 3rd to 7th at the Boston Convention and Exhibition Center. Join us at Booth #1168 for an immersive experience in one of the most dynamic gatherings in our industry.
Science Daily: Pharmacology News
JANUARY 26, 2024
An interdisciplinary team of researchers has developed a soft implantable device with dozens of sensors that can record single-neuron activity in the brain stably for months.
Drugs.com
JANUARY 24, 2024
WEDNESDAY, Jan. 24, 2024 -- Strange visual disturbances occur early in about 10% of Alzheimer's cases, and when this happens it almost always signals the impending arrival of the disease, a new study finds.The condition is called posterior cortical.
Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.
The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven
BioPharma Drive: Drug Pricing
JANUARY 26, 2024
The opinion would allow Abecma to be prescribed after two standard therapies and is the latest sign of CAR-T’s growing use in earlier cancer treatment.
Covalent Modifiers
JANUARY 25, 2024
Guanghui Tang , Wei Wang , Chengjun Zhu , Huisi Huang , Peng Chen , Xuan Wang , Manyi Xu , Jie Sun , Chong-Jing Zhang , Qicai Xiao , Liqian Gao , Zhi-Min Zhang , Shao Q. Yao , Angew. Chem. Int. Ed. 2024 , e202316394. [link] Advances in targeted covalent inhibitors (TCIs) have been made by using lysine-reactive chemistries. Few aminophiles possessing balanced reactivity/stability for the development of cell-active TCIs are however available.
Science Daily: Pharmacology News
JANUARY 26, 2024
Ground-penetrating radar on board NASA's Mars Perseverance rover has confirmed that the Jezero Crater, formed by an ancient meteor impact just north of the Martian equator, once harbored a vast lake and river delta. Over eons, sediment deposition and erosion within the crater shaped the geologic formations visible on the surface today. The discovery of lake sediments reinforces the hope that traces of life might be found in soil and rock samples collected by Perseverance.
Drugs.com
JANUARY 23, 2024
TUESDAY, Jan. 23, 2024 -- If you or someone close to you suffers from severe allergic reactions, you have probably heard there are new recommendations out that offer guidance on the diagnosis, management and treatment of anaphylaxis.The latest.
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Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.
BioPharma Drive: Drug Pricing
JANUARY 24, 2024
An 11-year-old boy born deaf can hear after receiving Lilly's genetic medicine. Others, including biotechs in China and Regeneron in the U.S., are taking aim at the same drug target.
ASPET
JANUARY 25, 2024
3,4-Methylenedioxymethamphetamine (MDMA) has shown efficacy as a medication adjunct for treating post-traumatic stress disorder (PTSD). However, MDMA is also used in non-medical contexts that pose risk for cardiovascular and neurological complications. It is well established that MDMA exerts its effects by stimulating transporter-mediated release of the monoamines, 5-hydroxytryptamine (5-HT), norepinephrine, and dopamine.
Science Daily: Pharmacology News
JANUARY 25, 2024
Data gathered through years of observation reveal an innocuous-seeming ant is disrupting an ecosystem in East Africa, illustrating the complex web of interactions among ants, trees, lions, zebras and buffaloes.
Drugs.com
JANUARY 22, 2024
MONDAY, Jan. 22, 2024 -- Depression affects half of the 6 million Americans who struggle with debilitating heart failure. Now, research shows that two leading modes of treatment -- antidepressants and an approach called behavioral activation.
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Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.
BioPharma Drive: Drug Pricing
JANUARY 22, 2024
Trodelvy didn’t outperform chemotherapy in a large study of people with a common lung tumor, a setback that sent company shares down by double digits.
Covalent Modifiers
JANUARY 20, 2024
Yuanjin Zhang , Zhonglin Liu , Marsha Hirschi , Oleg Brodsky , Eric Johnson , Sang Joon Won , Asako Nagata , Matthew D Petroski , Jaimeen D Majmudar , Sherry Niessen , Todd VanArsdale , Adam M Gilbert , Matthew M Hayward , Al E Stewart , Andrew R Nager , Bruno Melillo , Benjamin F Cravatt bioRxiv 2024.01.18.576274; doi: [link] More than half of the ~20,000 protein-encoding human genes have at least one paralog.
Science Daily: Pharmacology News
JANUARY 25, 2024
The intricate dance of nature often unfolds in mysterious ways, hidden from the naked eye. At the heart of this enigmatic tango lies a vital partnership: the symbiosis between plants and a type of fungi known as arbuscular mycorrhizal (AM) fungi. New groundbreaking research delves into this partnership, revealing key insights that deepen our understanding of plant-AM fungi interactions and could lead to advances in sustainable agriculture.
Drugs.com
JANUARY 25, 2024
THURSDAY, Jan. 25, 2024 -- Reiterating a warning first issued in November, the U.S. Food and Drug Administration is urging Americans to stay away from supplements containing tianeptine, known on the street as "gas station heroin.
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Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic
BioPharma Drive: Drug Pricing
JANUARY 24, 2024
The sector’s first IPO of 2024 could be positive signal for the handful of other companies that have recently laid out plans for initial public offerings.
Covalent Modifiers
JANUARY 24, 2024
Zhenguo Zhang, Lanyang Li, Hailun Xu, Chi-Lik Ken Lee, Zhenhua Jia, and Teck-Peng Loh Journal of the American Chemical Society 2024 146 (3), 1776-1782 DOI: 10.1021/jacs.3c12050 A new bioconjugation reagent containing silicon has been developed for the selective reaction with thiols. The inclusion of silicon significantly improves chemoselectivity and suppresses retro processes, thereby exceeding the capabilities of traditional reagents.
Science Daily: Pharmacology News
JANUARY 26, 2024
A new study found that graphene derived from metallurgical coke, a coal-based product, through flash Joule heating could serve not only as a reinforcing additive in cement but also as a replacement for sand in concrete.
Drugs.com
JANUARY 25, 2024
THURSDAY, Jan. 25, 2024 (HealthDay news) -- It’s been said that closing the toilet lid before flushing can prevent the spread of all germs, by keeping any flush-produced mist in the bowl.But a new study refutes that, showing that tiny viral.
BioPharma Drive: Drug Pricing
JANUARY 25, 2024
The company is developing an oral alternative to J&J’s lung cancer medicine Rybrevant, and adds to a trend of late-stage drugmakers finding investor demand on Wall Street.
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