Science Daily: Pharmacology News
APRIL 11, 2024
New hypothesis paper builds on a growing scientific consensus that Parkinson's disease route to the brain starts in either the nose or the gut and proposes that environmental toxicants are the likely source.
BioPharma Drive: Drug Pricing
APRIL 8, 2024
Recent biotech company acquisitions have put emerging schizophrenia treatments in focus. But many development hurdles still stand in the way of new medicines for the brain.
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Drugs.com
APRIL 12, 2024
FRIDAY, April 12, 2024 -- A chlamydia vaccine has triggered immune responses in an early trial, raising hopes that one day it might help curb the spread of the sexually transmitted infection (STI).There is currently no vaccine for chlamydia, which.
Forbes: Drug Truths
APRIL 11, 2024
Only biopharma could have combated Covid-19; no other industry has the capacity to do so. When the world was in crisis, this industry responded. If need be, it will again, despite the financial consequences.
Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.
The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven
Science Daily: Pharmacology News
APRIL 11, 2024
Star Trek's Holodeck is no longer just science fiction. Using AI, engineers have created a tool that can generate 3D environments, prompted by everyday language.
Drug Discovery Digest brings together the best content for drug research and development professionals from the widest variety of industry thought leaders.
Drugs.com
APRIL 8, 2024
MONDAY, April 8, 2024 -- New research questions the effectiveness of the U.S. Food and Drug Administration's accelerated drug approval program after finding that many cancer drugs remain unproven five years later.The study, published Sunday in the.
Covalent Modifiers
APRIL 8, 2024
Nils Pemberton, Nina Compagne, Argyrides Argyrou, Emma Evertsson, Anders Gunnarsson, Jason G. Kettle, Jonathan P. Orme, and Richard A. Ward ACS Medicinal Chemistry Letters 2024 DOI: 10.1021/acsmedchemlett.3c00425 To further facilitate the discovery of cysteine reactive covalent inhibitors, there is a need to develop new reactive groups beyond the traditional acrylamide-type warheads.
Science Daily: Pharmacology News
APRIL 9, 2024
Researchers have discovered a simple, but effective, strategy to help people reduce their feelings of anger. Disposing of a piece of paper containing your written thoughts on the cause of your anger can effectively neutralize it. This process is like a Japanese tradition called hakidashisara, in which people write their negative thoughts on a plate then destroy it.
BioPharma Drive: Drug Pricing
APRIL 10, 2024
The deal, which company CEO Reshma Kewalramani described as “just the right fit,” is the largest acquistion in Vertex’s 35-year history.
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Drugs.com
APRIL 12, 2024
FRIDAY, April 12, 2024 -- More than 100 measles cases have already been reported in the United States this year, a significant increase over previous years that threatens the country's attempts to eliminate the illness, federal health officials.
Covalent Modifiers
APRIL 7, 2024
Lavleen K. Mader and Jeffrey W. Keillor ACS Medicinal Chemistry Letters 2024 DOI: 10.1021/acsmedchemlett.4c00054 Experiments comprising a “pre-incubation” phase, where enzyme is incubated with inhibitor prior to the addition of assay substrate, are commonly used to evaluate covalent inhibitors, often via discontinuous or “endpoint” IC50 assays. However, due to the lack of mathematical tools to describe its biphasic time-dependent nature, this experiment has thus far been unable to provide kinact
Science Daily: Pharmacology News
APRIL 10, 2024
In a new breakthrough that could revolutionise medical and material engineering, scientists have developed a first-of-its-kind molecular device that controls the release of multiple small molecules using force.
BioPharma Drive: Drug Pricing
APRIL 10, 2024
The company said the pause is necessary to meet regulatory limits on nitrosamine, but added it will not affect commercial supply nor regulatory review of the drug in early breast cancer.
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Drugs.com
APRIL 11, 2024
THURSDAY, April 11, 2024 -- Kentucky resident Chasity Harney embraced a thoroughly healthy lifestyle -- eating right, exercising and never touching tobacco.So, her 2018 diagnosis of advanced lung cancer, which came at the age of 40, was a complete.
NIOSH Science Blog: Drugs
APRIL 10, 2024
Struck-by injuries are the leading cause of nonfatal injuries and second most common cause of fatalities among construction workers. From 2011 to 2022, there were 1,462 fatal occupational injuries that occurred at road construction sites.[1] Of these, 68% (n=1,000) were among workers in the construction industry (See figure) followed by workers in transportation and warehousing (11%; n=168) and professional and business services (9%; n=132) industries.
Science Daily: Pharmacology News
APRIL 10, 2024
Findings show a newly created drug can prevent runaway inflammation while still allowing the immune system to handle the virus, even when given late into infection.
BioPharma Drive: Drug Pricing
APRIL 8, 2024
Underrepresentation of women in clinical trials affects the resulting drugs that become available later. Even small changes could boost participation.
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Drugs.com
APRIL 11, 2024
THURSDAY, April 11, 2024 -- The discovery of a gene variant that rids the brain of toxic plaques linked to Alzheimer's might lead to new treatments for the disease, researchers report.The variant arises naturally in people who don't seem to get.
KIF1A
APRIL 6, 2024
#ScienceSaturday posts share exciting scientific developments and educational resources with the KAND community. Each week, Dr. Dylan Verden of KIF1A.ORG summarizes newly published KIF1A-related research and highlights progress in rare disease research and therapeutic development. KIF1A-Related Research Genetic Alterations in a Large Population of Italian Patients Affected by Neurodevelopmental Disorders We often talk about genetic disorders in the context of mutations that change a protein̵
Science Daily: Pharmacology News
APRIL 8, 2024
Engineers designed modular, spring-like devices to maximize the work of live muscle fibers so they can be harnessed to power biohybrid robots.
BioPharma Drive: Drug Pricing
APRIL 9, 2024
The company plans to submit the trial data to regulators in a bid to win approval of its vaccine Abrysvo in adults as young as 18 years old.
Drugs.com
APRIL 9, 2024
TUESDAY, April 9, 2024 -- For people struggling with both diabetes and a common type of heart failure, the weight-loss drug Wegovy may do more for their health than help them shed pounds, new research suggests.In the study, published Saturday in.
Perficient: Drug Development
APRIL 11, 2024
Documentation is a crucial part of your analytics implementation. From your Solution Design Reference document to your internal wiki for all resources, making sure that you can write and edit your documentation is key to ensuring a cohesive and thorough understanding of your implementation. With effective documentation, you can: Prevent knowledge gaps among team members and assist in onboarding efforts.
Science Daily: Pharmacology News
APRIL 11, 2024
The full power of next-generation quantum computing could soon be harnessed by millions of individuals and companies, thanks to a breakthrough guaranteeing security and privacy. This advance promises to unlock the transformative potential of cloud-based quantum computing.
BioPharma Drive: Drug Pricing
APRIL 8, 2024
The results were the second time Novo has shown its weight loss treatment can help with the condition, and may help it secure broader use of the drug.
Drugs.com
APRIL 8, 2024
MONDAY, April 8, 2024 -- A pancreatic cancer vaccine has continued to protect a small group of patients from their cancer coming back, three years after receiving the jab, a new study says.Eight patients have not had their pancreatic cancer recur.
Drug Target Review
APRIL 12, 2024
Delivery of ribonucleoprotein (RNP) into cells is an essential factor for successful CRISPR gene editing. However, this is difficult to guarantee using traditional CRISPR gene editing methods, especially in hard-to-transfect cells. The standard CRISPR technique involves gathering a group of cells and then electroporating them, using short high-voltage pulses to overcome the barrier of their cell membranes.
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