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Consuming moderate amounts of coffee and caffeine regularly may offer a protective effect against developing multiple cardiometabolic diseases, including type 2 diabetes, coronary heart disease and stroke, according to new research.
Industry insiders hope the Fed’s decision to cut rates for the first time in years will boost biotech investment. But the long-awaited move won’t cure all that ails the sector, others cautioned.
MONDAY, Sept. 16, 2024 -- Tiny puffs from asthma inhalers could be causing big climate problems for Mother Earth, a new study warns.Each inhaler dose contains some of the most potent greenhouse gases known, and they are adding up, researchers.
In a recent webinar, Janice Darlington from Collaborative Drug Discovery (CDD) with Tamsin Mansley from Optibrium discussed the importance of collaboration in drug discovery and showcased how their software platforms, CDD Vault and StarDrop , can enhance collaborative efforts.
Speaker: Simran Kaur, Co-founder & CEO at Tattva.Health
AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!
A new study provides a list of the wildlife species present at the market from which SARS-CoV-2, the virus responsible for the COVID-19 pandemic, most likely arose in late 2019. The study is based on a new analysis of metatranscriptomic data released by the Chinese Center for Disease Control and Prevention (CDC). The data come from more than 800 samples collected in and around the Huanan Seafood Wholesale market beginning on January 1, 2020, and from viral genomes reported from early COVID-19 pa
Final follow-up results suggest Opdivo and Yervoy could be close to a cure for some people with advanced melanoma, shifting how doctors administer follow-up care.
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Drug Discovery Digest brings together the best content for drug research and development professionals from the widest variety of industry thought leaders.
Final follow-up results suggest Opdivo and Yervoy could be close to a cure for some people with advanced melanoma, shifting how doctors administer follow-up care.
MONDAY, Sept. 16, 2024 -- Fatty liver disease linked to diabetes and obesity can easily progress to liver cirrhosis, but new research suggests that GLP-1 medicines like Ozempic can help stop that. In a new decades-long study, veterans with diabetes.
Liang Ouyang, Wen Shuai, Panpan Yang, Huan Xiao, Yumeng Zhu, Faqian Bu, Aoxue Wang, Qiu Sun, Guan Wang Angewandte Chemie 2024 e202411037 [link] c-Jun N-terminal kinases (JNKs) including JNK1/2/3 are key members of mitogen-activated protein kinase family. Wherein JNK3 is specifically expressed in brain and emerges as therapeutic target, especially for neurodegenerative diseases.
A new, wide-ranging exploration of human remains casts doubt on a long-standing theory in archaeology known as the Kurgan hypothesis -- which, among other claims, suggests that humans first domesticated horses as early as the fourth millennium B.C.
Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.
The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven
FRIDAY, Sept. 20, 2024 -- The days of waiting for a flu shot at your doctor's office or local pharmacy may be over: The U.S. Food and Drug Administration on Friday approved FluMist nasal spray as the first influenza vaccine that can be.
Dong, S., Huang, H., Li, J. et al. Commun Chem 7 , 201 (2024). [link] Multi-functional cysteine-targeting covalent warheads possess significant therapeutic potential in medicinal chemistry and chemical biology. Herein, we present novel unsaturated and asymmetric ketone (oxazolinosene) scaffolds that selectively conjugate cysteine residues of peptides and bovine serum albumin under normal physiological conditions.
Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.
WEDNESDAY, Sept. 18, 2024 -- Women with early stage breast cancer may now take Kisquali, a medication already approved for advanced disease, following the U.S. Food and Drug Administration's expanded approval of the treatment, drug maker Novartis.
Post-traumatic stress disorder (PTSD) is caused by exposure to a traumatic or stressful event. Symptoms related to this disorder include persistent re-experiencing of memories and fear generalization. Current pharmacological treatments for PTSD are insufficient, with fewer than 30% of patients reporting symptom remission. This study aims to determine the efficacy of acute ( R,S) ketamine and chronic fluoxetine (FLX) in reducing fear memory and fear generalization.
Researchers have uncovered key insights into the dangerous phenomenon of 'river avulsion,' offering a way to predict when and where rivers may suddenly and dramatically change course.
The decision against Syfovre’s approval follows efforts by Apellis to have reviewers reevaluate clinical evidence multiple times and, according to an analyst, will lead to a restructuring of the company’s operations in Europe.
Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.
MONDAY, Sept. 16, 2024 -- People should prepare for the fall cold and flu season by getting the updated influenza and COVID-19 vaccinations, an infectious diseases expert says.“When my patients ask me if they should be getting a COVID vaccine this y.
Post-traumatic stress disorder (PTSD) is a debilitating psychiatric condition that develops following exposure to a traumatic event. Individuals with this condition experience numerous physiological and behavioral alterations, including intrusive memories, avoidance of trauma-related stimuli, heightened anxiety, hypervigilance, impaired cognition, elevated resting heart rate and blood pressure, and altered neuroendocrine function, to name a few.
Van Gogh's brushstrokes in 'The Starry Night' create an illusion of sky movement so convincing it led researchers to wonder how closely it aligns with the physics of real skies. Marine sciences and fluid dynamics specialists analyzed the painting to uncover what they call the hidden turbulence in the artwork. They used brushstrokes to examine the shape, energy, and scaling of atmospheric characteristics of the otherwise invisible atmosphere and used the relative brightness of the varying paint c
Summary study results show Ascendis’ drug for achondroplasia could be competitive to BioMarin's Voxzogo, which is the foundation of the latter company's growth plans.
Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic
FRIDAY, Sept. 20, 2024 -- The days of waiting for a flu shot at your doctor's office or local pharmacy may be over: The U.S. Food and Drug Administration on Friday approved FluMist nasal spray as the first influenza vaccine that can be.
Create ELN Templates: Templates are a great way to provide organization and uniformity to ELN entries, saving users time and ensuring data is easily digestible. Once an entry is ready to become a template, your Vault Administrator can publish it by clicking the template icon at the top of the page. Provide a name, decide which specific ELN fields should be included and whether to make them required or optional.
A new study offers the most detailed glimpse yet into how Earth's surface temperature has changed over the past 485 million years. The data show that Earth has been and can be warmer than today -- but humans and animals cannot adapt fast enough to keep up with human-caused climate change.
GC Therapeutics claims it can create off-the-shelf therapies from induced pluripotent stem cells faster than by current methods with a simpler process.
TUESDAY, Sept. 17, 2024 -- Millions more people will die annually from antibiotic-resistant infections over the next 25 years unless steps are taken to counter this growing health threat, a new study warns.The number of deaths linked to.
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