ASPET

SEPTEMBER 20, 2024

Post-traumatic stress disorder (PTSD) is caused by exposure to a traumatic or stressful event. Symptoms related to this disorder include persistent re-experiencing of memories and fear generalization. Current pharmacological treatments for PTSD are insufficient, with fewer than 30% of patients reporting symptom remission. This study aims to determine the efficacy of acute ( R,S) ketamine and chronic fluoxetine (FLX) in reducing fear memory and fear generalization.

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Treatment Research 190

Science Daily: Pharmacology News

SEPTEMBER 17, 2024

Consuming moderate amounts of coffee and caffeine regularly may offer a protective effect against developing multiple cardiometabolic diseases, including type 2 diabetes, coronary heart disease and stroke, according to new research.

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Disease Research 145

BioPharma Drive: Drug Pricing

SEPTEMBER 19, 2024

Industry insiders hope the Fed’s decision to cut rates for the first time in years will boost biotech investment. But the long-awaited move won’t cure all that ails the sector, others cautioned.

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Drugs.com

SEPTEMBER 16, 2024

MONDAY, Sept. 16, 2024 -- Tiny puffs from asthma inhalers could be causing big climate problems for Mother Earth, a new study warns.Each inhaler dose contains some of the most potent greenhouse gases known, and they are adding up, researchers.

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Research 119

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

Treatment

ASPET

SEPTEMBER 16, 2024

Post-traumatic stress disorder (PTSD) is a debilitating psychiatric condition that develops following exposure to a traumatic event. Individuals with this condition experience numerous physiological and behavioral alterations, including intrusive memories, avoidance of trauma-related stimuli, heightened anxiety, hypervigilance, impaired cognition, elevated resting heart rate and blood pressure, and altered neuroendocrine function, to name a few.

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Treatment Research 189

Science Daily: Pharmacology News

SEPTEMBER 19, 2024

A new study provides a list of the wildlife species present at the market from which SARS-CoV-2, the virus responsible for the COVID-19 pandemic, most likely arose in late 2019. The study is based on a new analysis of metatranscriptomic data released by the Chinese Center for Disease Control and Prevention (CDC). The data come from more than 800 samples collected in and around the Huanan Seafood Wholesale market beginning on January 1, 2020, and from viral genomes reported from early COVID-19 pa

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Marketing Virus Disease 135

Drugs.com

SEPTEMBER 16, 2024

MONDAY, Sept. 16, 2024 -- Fatty liver disease linked to diabetes and obesity can easily progress to liver cirrhosis, but new research suggests that GLP-1 medicines like Ozempic can help stop that. In a new decades-long study, veterans with diabetes.

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Disease Research 119

Perficient: Drug Development

SEPTEMBER 18, 2024

This post is the second in a series of four about estimating project hours. Part 1: Sandbagging & Lowballing Part 2: Dependencies & Creep Coming Soon: Part 3: Assumptions & Uncertainty Part 4: The Emotional Conclusion Continuing our dive into project estimating, let’s talk about two more problem areas: dependencies and project creep. These two can turn your pristine project plan into a tangled mess.

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Production 116

Science Daily: Pharmacology News

SEPTEMBER 20, 2024

A new, wide-ranging exploration of human remains casts doubt on a long-standing theory in archaeology known as the Kurgan hypothesis -- which, among other claims, suggests that humans first domesticated horses as early as the fourth millennium B.C.

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BioPharma Drive: Drug Pricing

SEPTEMBER 17, 2024

The FDA previously rejected patritumab deruxtecan over manufacturing issues. Tuesday's study data should boost the companies' case, however.

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Trials FDA 124

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Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

Clinical Trials

Drugs.com

SEPTEMBER 20, 2024

FRIDAY, Sept. 20, 2024 -- The days of waiting for a flu shot at your doctor's office or local pharmacy may be over: The U.S. Food and Drug Administration on Friday approved FluMist nasal spray as the first influenza vaccine that can be.

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FDA Approval Vaccine Pharmacy Doctors 116

Broad Institute

SEPTEMBER 18, 2024

Scientists identify a unique combination of bacterial strains that could treat antibiotic-resistant gut infections By Allessandra DiCorato September 18, 2024 Breadcrumb Home Scientists identify a unique combination of bacterial strains that could treat antibiotic-resistant gut infections The microbes control the growth of harmful bacteria in mice, promoting a healthier intestinal microbiome.

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Medical Schools Disease Hospitals Treatment 114

Science Daily: Pharmacology News

SEPTEMBER 18, 2024

A class of drugs for diabetes may be associated with a lower risk of dementia and Parkinson's disease, according to a new study.

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Disease Drugs 131

BioPharma Drive: Drug Pricing

SEPTEMBER 17, 2024

The funding will support mid-stage testing of a drug the company believes to have the potential to treat a range of neurodegenerative conditions.

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Drugs 122

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Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

Clinical Trials

Drugs.com

SEPTEMBER 18, 2024

WEDNESDAY, Sept. 18, 2024 -- Women with early stage breast cancer may now take Kisquali, a medication already approved for advanced disease, following the U.S. Food and Drug Administration's expanded approval of the treatment, drug maker Novartis.

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Antidote

SEPTEMBER 16, 2024

Receiving a Parkinson’s diagnosis is a life-altering event that nearly 1 million people in the United States have experienced. Parkinson’s disease symptoms can vary from person to person. Receiving a diagnosis often requires several steps. In this blog, we’ll be sharing more details about the disease and discussing opportunities for individuals to get involved in Parkinson’s research.

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Disease Research 114

Science Daily: Pharmacology News

SEPTEMBER 19, 2024

Researchers have uncovered key insights into the dangerous phenomenon of 'river avulsion,' offering a way to predict when and where rivers may suddenly and dramatically change course.

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Research 130

BioPharma Drive: Drug Pricing

SEPTEMBER 20, 2024

The decision against Syfovre’s approval follows efforts by Apellis to have reviewers reevaluate clinical evidence multiple times and, according to an analyst, will lead to a restructuring of the company’s operations in Europe.

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Drugs 119

Advertisement

Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

Clinical Trials

Drugs.com

SEPTEMBER 16, 2024

MONDAY, Sept. 16, 2024 -- People should prepare for the fall cold and flu season by getting the updated influenza and COVID-19 vaccinations, an infectious diseases expert says.“When my patients ask me if they should be getting a COVID vaccine this y.

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Vaccine Disease 116

Perficient: Drug Development

SEPTEMBER 17, 2024

As an Optimizely expert, I eagerly anticipate this time of year due to the exciting Optimizely events happening worldwide. These include Opticon, the main conference for customers, the Optimizely OMVP Summit, a developer meetup, and the Optimizely Hackathon. During these events, we learn about new product releases and discover innovative ways to drive success for our customers.

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Science Daily: Pharmacology News

SEPTEMBER 17, 2024

Van Gogh's brushstrokes in 'The Starry Night' create an illusion of sky movement so convincing it led researchers to wonder how closely it aligns with the physics of real skies. Marine sciences and fluid dynamics specialists analyzed the painting to uncover what they call the hidden turbulence in the artwork. They used brushstrokes to examine the shape, energy, and scaling of atmospheric characteristics of the otherwise invisible atmosphere and used the relative brightness of the varying paint c

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Science Research 130

BioPharma Drive: Drug Pricing

SEPTEMBER 17, 2024

Summary study results show Ascendis’ drug for achondroplasia could be competitive to BioMarin's Voxzogo, which is the foundation of the latter company's growth plans.

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Trials Drugs 113

Drugs.com

SEPTEMBER 20, 2024

FRIDAY, Sept. 20, 2024 -- The days of waiting for a flu shot at your doctor's office or local pharmacy may be over: The U.S. Food and Drug Administration on Friday approved FluMist nasal spray as the first influenza vaccine that can be.

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FDA Approval Vaccine Pharmacy Doctors 111

Drug Patent Watch

SEPTEMBER 19, 2024

The generic drug market in the United States is characterized by significant price volatility and shortages, driven by the structure of the market and the incentives for manufacturers. To address these issues, several market-based proposals have been put forth to optimize generic drug cost and availability.

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Drugs Marketing 104

Science Daily: Pharmacology News

SEPTEMBER 16, 2024

An experiment tested six generative large language models against students in an online introductory biomedical and health informatics course. The models scored higher than as many as three quarters of the real-world students in the class.

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Research 130

BioPharma Drive: Drug Pricing

SEPTEMBER 19, 2024

According to the company, the results are the first time an antiviral drug has reduced transmission of a respiratory virus in a global Phase 3 trial.

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Virus Trials Drugs 105

Drugs.com

SEPTEMBER 20, 2024

FRIDAY, Sept. 20, 2024 -- Doctors sometimes turn to antidepressants as a means of easing older people's physical pain, but a new expert review finds there's little evidence to support the practice.Antidepressants may even come with hazards for.

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Doctors 110

Drug Patent Watch

SEPTEMBER 18, 2024

The biopharmaceutical industry is constantly evolving, with the demand for complex biologics on the rise. To stay competitive, companies must navigate the complexities of biopharmaceutical development while managing costs effectively. One key strategy for achieving this balance is partnering with Contract Development and Manufacturing Organizations (CDMOs).

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Science Daily: Pharmacology News

SEPTEMBER 19, 2024

A new study offers the most detailed glimpse yet into how Earth's surface temperature has changed over the past 485 million years. The data show that Earth has been and can be warmer than today -- but humans and animals cannot adapt fast enough to keep up with human-caused climate change.

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ASPET

SEPTEMBER 20, 2024

Despite considerable efforts, there remains no FDA-approved medications for cocaine use disorder (CUD). One strategy to mitigate cocaine craving and relapse is to elevate dopamine (DA). The DA transport inhibitor and releaser d -amphetamine has been shown to decrease cocaine self-administration (SA), although it has abuse liability. Recently, several modafinil analogues reduced cocaine SA in rats and monkeys, including JJC8-088, characterized as "cocaine like" in rats, and JJC8-091, characterize

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FDA Approval Treatment FDA Drugs 100

Drugs.com

SEPTEMBER 17, 2024

TUESDAY, Sept. 17, 2024 -- Millions more people will die annually from antibiotic-resistant infections over the next 25 years unless steps are taken to counter this growing health threat, a new study warns.The number of deaths linked to.

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Collaborative Drug

SEPTEMBER 19, 2024

In a recent webinar, Janice Darlington from Collaborative Drug Discovery (CDD) with Tamsin Mansley from Optibrium discussed the importance of collaboration in drug discovery and showcased how their software platforms, CDD Vault and StarDrop , can enhance collaborative efforts.

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Drugs 99

Science Daily: Pharmacology News

SEPTEMBER 18, 2024

New archaeological research has discovered for the first time clear links between fossils of the iconic Australian dingo, and dogs from East Asia and New Guinea.

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Research 127