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Pharma dealmaking for drugs invented in China is putting pressure on U.S. biotechs to compete harder, according to investors and executives interviewed by BioPharma Dive at the J.P. Morgan Healthcare Conference.
New proteins not found in nature have now been designed to counteract certain highly poisonous components of snake venom. The deep learning, computational methods for developing these toxin-neutralizing proteins offer hope for creating safer, more cost-effective and more readily available therapeutics than those currently in use. Each year more than 2 million people suffer snakebites.
Gene editing extends lifespan in mouse model of prion disease By Allessandra DiCorato January 14, 2025 Breadcrumb Home Gene editing extends lifespan in mouse model of prion disease A single-letter edit in DNA reduces levels of the disease-causing prion protein in the brain and could lead to a preventative, one-time treatment for the deadly neurodegenerative disorder.
Traditional computational drug discovery relies almost exclusively on highly task-specific computational models for hit identification and lead optimization. Traditional computational drug discovery relies almost exclusively on highly task-specific computational models for hit identification and lead optimization. Adapting these specialized models to new tasks requires substantial time, computational power, and expertisechallenges that grow when researchers simultaneously work across multiple ta
Speaker: Simran Kaur, Co-founder & CEO at Tattva.Health
AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!
AbbVie's CEO hinted his company may be less willing to invest in psychiatry after a costly setback, while Lilly explained what it got wrong forecasting GLP-1 drug demand.
Scientists have succeeded in controlling the structure and function of biological membranes with the help of 'DNA origami'. The system they developed may facilitate the transportation of large therapeutic loads into cells. This opens up a new way for the targeted administration of medication and other therapeutic interventions. Thus, a very valuable instrument can be added to the toolbox of synthetic biology.
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Drug Discovery Digest brings together the best content for drug research and development professionals from the widest variety of industry thought leaders.
Scientists have succeeded in controlling the structure and function of biological membranes with the help of 'DNA origami'. The system they developed may facilitate the transportation of large therapeutic loads into cells. This opens up a new way for the targeted administration of medication and other therapeutic interventions. Thus, a very valuable instrument can be added to the toolbox of synthetic biology.
THURSDAY, Jan. 16, 2025 -- Cutting-edge targeted therapies are pushing back the line between life and death for cancer patients.However, these targeted cancer drugs frequently arent benefitting members of ethnic and racial minorities in the U.S., a.
As clinical trials become increasingly complex, particularly in decentralized trials and rare disease studies, sponsors experience increased challenges in site selection, forecasting and resourcing, and patient recruitment and enrollment. Advanced artificial intelligence (AI) and machine learning solutions are revolutionizing critical challenge areas.
Roche's core research spans five large areas. Boris Zaïtra, who now leads corporate business development, is confident his team of dealmakers can juggle them.
Increasingly common since 1980, persistent multi-year droughts will continue to advance with the warming climate, warns a new study. This publicly available forty-year global quantitative inventory seeks to inform policy regarding the environmental impact of human-induced climate change. It also detected previously 'overlooked' events.
Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.
The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven
MONDAY, Jan. 13, 2025 (HealthDay news) -- The sleep aid Ambien could be allowing toxic proteins to pollute the brain, potentially increasing a persons risk of disorders like Alzheimers disease.Drugs like the main ingredient in Ambien, zolpidem, sup.
Drug discovery scientists spend their days developing and testing complex hypotheses, leveraging data and expertise through workflows that utilise available tools. Operating a workflow, such as the one described in Figure 1, involves several key considerations that affect both the accuracy of results and the efficiency of the research process. Defining the research question A well-defined research question is the cornerstone of an effective scientific workflow in drug discovery.
The Atlantic Meridional Overturning Circulation (AMOC) has not slowed down since the mid-20th century based on the North Atlantic air-sea heat fluxes over that time. This finding contrasts with studies that have estimated a decline in the AMOC, likely because previous studies rely on sea surface temperature measurements to understand how the AMOC has changed.
Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.
FRIDAY, Jan. 17, 2025 -- Women past menopause can protect themselves from future fractures through infrequent, cheap IV infusions of a bone-strengthening drug. Women 50 to 60 who got two IV infusions of zoledronate (Reclast) within five years had a.
Identifying drug patents is crucial for various stakeholders, including researchers, legal professionals, and business strategists. While Google Patents is a widely used tool for searching patent information, it may not be the most effective solution for identifying drug patents. This article explores the limitations of Google Patents in this context and suggests alternative approaches.
Researchers have developed a drastically smaller and more energy efficient method of creating coveted photon pairs that influence each other from any distance. The technology could transform computing, telecommunications, and sensing.
Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.
TUESDAY, Jan. 14, 2025 -- A deadly bird flu outbreak has wreaked havoc on U.S. chicken farms, claiming the lives of over 20 million egg-laying chickens last quarter, marking the worst impact on America's egg supply since the outbreak began in.
Imagine youre a skilled craftsman working in a massive warehouse. Every day, your task is to process thousands of unique items and ensure that each one is properly logged and stored. But lets face it mistakes happen. Sometimes an item gets mislabeled or damaged, and you need to know which ones to fix, and which ones made it safely through. In Salesforce, when working with a batch class that processes thousands or even millions of records, Database.SaveResult acts as your trusty supervisor, keep
Astrophysicists have imaged a large number of exocomet belts around nearby stars, and the tiny pebbles within them. The crystal-clear images show light being emitted from these millimeter-sized pebbles within the belts that orbit 74 nearby stars of a wide variety of ages -- from those that are just emerging from birth to those in more mature systems like our own Solar System.
Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic
TUESDAY, Jan. 14, 2025 -- All women 65 and older should continue to be screened for osteoporosis, the nation’s leading preventive health panel says in an updated recommendation. The U.S. Preventive Services Task Force also recommends.
Early Commercial Planning: Mitigate Patient Access Challenges for Cell and Gene Therapies swheeler Thu, 01/16/2025 - 17:26 Thu, 03/06/2025 - 11:00 Resource Type Webinar Fran Gregory, PharmD, MBA Josh Marsh Kathryne Kirk Kelly Kester Duration 60 minutes Cell and gene therapies (CGTs) offer fresh hope to patients with serious and debilitating diseases, often where no other treatment options are available.
Novo sells semaglutide as Ozempic and Rybelsus for diabetes and as Wegovy for obesity. In price talks, CMS will treat the different forms as a single product.
A new study shows that the risk of developing dementia anytime after age 55 among Americans is 42%, more than double the risk reported by older studies.
FRIDAY, Jan. 17, 2025 -- The U.S. Centers for Disease Control and Prevention (CDC) confirmed another human H5N1 avian flu case -- otherwise known as bird flu -- in California on Thursday, bringing the nationwide total of cases to 67.California has.
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