Sat.Sep 07, 2024 - Fri.Sep 13, 2024

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Microscale robot folds into 3D shapes and crawls

Science Daily: Pharmacology News

Researchers have created microscale robots less than 1 millimeter in size that are printed as a 2D hexagonal 'metasheet' but, with a jolt of electricity, morph into preprogrammed 3D shapes and crawl.

Research 140
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Three biotechs raise $700M in rare burst of IPO activity

BioPharma Drive: Drug Pricing

The offerings by Bicara, Zenas and MBX give a glimpse into what industry insiders describe as a backlog of mature startups waiting for the right opportunity to test public markets.

Marketing 130
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It's High Number of Guns, Not Mental Health Crises, That Drives U.S. Gun Deaths: Study

Drugs.com

WEDNESDAY, Sept. 11, 2024 -- Widespread and easy access to guns is the reason behind the shockingly high rate of firearm deaths in the United States, and not any rise in mental health problems suffered by perpetrators, a new study shows.The United.

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CDD Vault Update (September 2024)

Collaborative Drug

Chemical Safety Information: When working in a lab, you must understand the risks associated with handling chemicals. CDD Vault now displays safety information obtained from PubChem as a helpful reminder. If available, you will find hazard pictograms next to the name at the top of the molecule page.

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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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New AI can ID brain patterns related to specific behavior

Science Daily: Pharmacology News

Scientists have developed a new AI algorithm that can separate brain patterns related to a particular behavior. This work promises to improve brain-computer interfaces and aid with the discovery of new brain patterns.

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Summit lung cancer drug shows ‘striking’ benefit over Keytruda

BioPharma Drive: Drug Pricing

Study results provide much-anticipated details to Summit’s claim earlier this year that its drug “decisively beat” Merck’s dominant immunotherapy.

Drugs 135

More Trending

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Revised Final Guidance on Nitrosamines Offers New Recommendations for Assessment and Control

FDA Law Blog: Biosimilars

By John W.M. Claud — Last week, FDA revised one of its two guidances relating to nitrosamines, Control of Nitrosamine Impurities in Human Drugs. Nitrosamines are impurities that can form during drug manufacturing and are considered potentially potent carcinogens. One specific kind of nitrosamines called N-nitrosamine drug substance-related impurities, or NDSRIs, are especially vexing to FDA and to industry because they mimic the structure of the specific active pharmaceutical ingredients (API),

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Climate-change-triggered 2023 mega-landslide caused Earth to vibrate for nine days

Science Daily: Pharmacology News

A landslide in a remote part of Greenland caused a 200 meter (650 foot) mega-tsunami that sloshed back and forth across a fjord for nine days, generating vibrations throughout Earth, according to a new study. The study concluded that this movement of water was the cause of a mysterious, global seismic signal that lasted for nine days and puzzled seismologists in September 2023.

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Gene therapy startup emerges with green light for first-of-its-kind trial

BioPharma Drive: Drug Pricing

Spun out of research at Nationwide Children’s Hospital, Vironexis claims it will be the first company to start a study testing a cancer drug delivered via the adeno-associated viruses commonly used in genetic medicines.

Therapies 111
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'Self-Medicating' Gorillas Are Leading People to New Medicines

Drugs.com

FRIDAY, Sept. 13, 2024 -- Humans could learn a few medical tips from their gorilla cousins, a new study says.Four plants used by wild gorillas in Gabon have antibacterial and antioxidant properties, researcher reported Sept. 11 in the journal PLOS.

Research 116
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How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

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Content Hub: Data Model Simplified

Perficient: Drug Development

Sitecore Content Hub is a world-class platform for centralizing and managing content across various channels. It helps businesses organize and streamline often chaotic, messy content operations. It does this by providing an architecture or schema for content and its interconnections. A schema defines how different types of assets are structured, organized, related to each other.

Marketing 105
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Ancient DNA from Rapa Nui (Easter Island) refutes best-selling population collapse theory

Science Daily: Pharmacology News

Rapa Nui (Easter Island) with its gigantic statues and treeless landscape has fascinated researchers for centuries. A new genetic study disproves the popular theory that the Rapanui population collapsed as a result of an 'ecocide' and shows that the Rapanui admixed with Indigenous Americans centuries before Europeans arrived on the island.

DNA 130
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Moderna, trailing rivals, checks its RSV shot expectations

BioPharma Drive: Drug Pricing

During an investor presentation Thursday, executives admitted to being overly optimistic their vaccine could wrest significant market share away from GSK's and Pfizer's products this year.

Vaccine 107
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Ozempic, Mounjaro Help People With Type 1 Diabetes Control Blood Sugar, Lose Weight

Drugs.com

FRIDAY, Sept. 13, 2024 -- Initially approved to treat type 2 diabetes, Ozempic and Mounjaro also can help people with type 1 diabetes lose weight and control their blood sugar levels, a new study finds.Overweight or obese type 1 diabetics taking.

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Deliver Fast, Flexible Clinical Trial Insights with Spotfire

Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

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On Fables and Nuanced Charts

Codon

In this Column, Spencer Greenberg and Amber Dawn Ace explain how charts can inadvertently manipulate reality. In 1994, the U.S. Congress passed the largest crime bill in U.S. history, called the Violent Crime Control and Law Enforcement Act. The bill allocated billions of dollars to build more prisons and hire 100,000 new police officers, among other things.

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Path to prosperity for planet and people shrinking rapidly, scientists warn

Science Daily: Pharmacology News

Our planet will only remain able to provide even the most basic standard of living for everyone in the future if economic systems and technologies are dramatically transformed and critical resources are more fairly used, managed and shared, a new report shows.

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Beyond data: Humanizing clinical research with Avacare

Fierce BioTech

Navigating today’s rapidly evolving clinical trial landscape can be tough. | With intricate protocols and shifting regulatory demands, it’s more difficult than ever to find and keep participants, as well as gather reliable data.

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Ozempic or Saxenda for Weight Loss: Which Works Best?

Drugs.com

FRIDAY, Sept. 13, 2024 -- Ozempic and its weight-loss cousin, Wegovy, outperform another longstanding weight-loss drug that targets the same hormone associated with blood sugar and appetite, a new study finds.Ozempic and Wegovy (semaglutide).

Drugs 116
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Clinical Data Like You´ve Never Seen It Before: Why Spotfire Is the Leading Tool for Clinical Analytics

Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

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Keypoint Newsletter: Health Equity Recap

keypoint

By Shannon Weiman In 2023 we launched a new initiative to add health equity programming to select meetings to raise awareness for health disparities in various fields and initiate discussions on how to rectify these health inequities through scientific research and discovery. These messages are of critical importance to the global research community, so we are releasing the audio recordings of these Health Equity Forums open access, to inform broader audiences about these issues and inspire them

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Powered by renewable energy, microbes turn CO2 into protein and vitamins

Science Daily: Pharmacology News

Researchers can harvest protein and vitamin B9 from microbes by feeding them nothing much more than hydrogen, oxygen, and CO2. The technology runs on renewable energy to produce a sustainable, micronutrient-enriched protein alternative that may one day make it to our plates.

Research 121
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Fulcrum shares collapse as Sanofi-partnered muscular dystrophy drug fails key test

BioPharma Drive: Drug Pricing

The biotech will now suspend development of a drug prospect that Sanofi acquired partial rights to just four months ago.

Drugs 114
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Weight-Loss Pill Saxenda Helps Kids as Young as 6

Drugs.com

WEDNESDAY, Sept. 11, 2024 -- The weight-loss drug liraglutide helped obese children lower their BMI and reach a healthier weight, researchers report.The findings, published Tuesday in the New England Journal of Medicine and presented.

Research 116
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Leveraging Nanotechnology in Generic Drug Development: Enhancing Efficacy and Safety

Drug Patent Watch

The pharmaceutical industry has witnessed significant advancements in recent years, particularly in the realm of nanotechnology. This innovative field has revolutionized the way drugs are developed, manufactured, and delivered to patients.

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Researchers combine the power of AI and the connectome to predict brain cell activity

Science Daily: Pharmacology News

With maps of the connections between neurons and artificial intelligence methods, researchers can now do what they never thought possible: predict the activity of individual neurons without making a single measurement in a living brain.

Research 121
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Keypoint Newsletter: September 2024

keypoint

Checkout Health Equity highlights, climate & sustainability conferences, emerging topics & more from Keystone Symposia in our September 2024 Keypoint Newsletter.

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More Women Underwent Surgical Sterilization After Fall of Roe v. Wade

Drugs.com

WEDNESDAY, Sept. 11, 2024 -- As fears of the consequences of an unintended pregnancy rose after Roe v. Wade was overturned in 2022, rates of surgical sterilization rose in those states most affected by the decision, new research shows. Rates of.

Research 116
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Optimizing Partnerships for Generic Drug Development Success

Drug Patent Watch

The generic drug market has experienced significant growth over the past few decades, driven by the passage of the Hatch-Waxman Act in 1984 and subsequent legislation. Today, the market is more competitive than ever, with generic drugs accounting for over 90% of all prescriptions in the United States.

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Risky play exercises an ancestral need to push limits

Science Daily: Pharmacology News

Since their invention in the 1920s, jungle gyms and monkey bars have become both fixtures of playgrounds and symbols of childhood injury that anxious caretakers want removed. Anthropologists mark 100 years of the iconic playground equipment by arguing that risky play exercises a biological need passed on from apes and early humans for children to independently test and expand their physical and cognitive abilities in a context in which injury is possible but avoidable.

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How Clinical Trial Trends are Redefining Drug Development

Quanticate

With the implementation of technology rapidly increasing, stricter regulatory standards, and growing demand for innovative treatments, the trends within the industry continue to evolve, impacting the future of clinical trials both positively and negatively. In our article, we cover the key trends that have been shaping clinical trials so far in 2024, and those that are predicted to continue into 2025.

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Over 5 Million Americans Could Benefit If Psilocybin Approved for Depression: Study

Drugs.com

FRIDAY, Sept. 13, 2024 -- Over 5 million Americans could benefit if the U.S. Food and Drug Administration approves the "magic mushroom" psychedelic psilocybin as a treatment for depression, researchers estimate.“While our analysis is a crucial f.

Treatment 115
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Keypoint Newsletter: 2024 Season Highlights

keypoint

In June we wrapped up our 2024 conference season, aligning with the academic calendar. Altogether we hosted 52 conferences across North America, Europe and Asia, serving nearly 9,000 participants and providing financial aid to over 500 students, post-docs, underrepresented scientists and scientists from low- and middle-income countries. Find out more about our attendees below and see what they are saying about Keystone Symposia!

Science 83
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'Out-of-body' research could lead to new ways to promote social harmony

Science Daily: Pharmacology News

Out-of-body experiences, such as near-death experiences, can have a 'transformative' effect on people's ability to experience empathy and connect with others, new research explains.

Research 122
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Antibody Validation for Flow Cytometry

addgene Blog

Antibody validation is to confirm (or refute) that the antibody is selectively detecting the target-of-interest in your assay and sample-of-interest. The approaches available broadly map onto the five pillars of antibody validation (see: Uhlen et al., 2016 ). In this post, we will describe the approaches that can be used to determine selectivity of an antibody for flow cytometry experiments.

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