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A new study reveals how the duplication of the salivary amylase gene may not only have helped shape human adaptation to starchy foods, but may have occurred as far back as more than 800,000 years ago, long before the advent of farming.
The results provide the first clinical evidence of RNA editing, a burgeoning field that's drawn interest from biotechs and pharmaceutical companies alike.
THURSDAY, Oct. 17, 2024 -- A national recall of meat and poultry has been expanded to include close to 12 million pounds of products that may have been contaminated with listeria, U.S. health officials announced. In addition, the updated recall.
Xingyu Ma, Manyi Xu, Fengge Wang, Tingting Hu, Xinyuan Chena and Chong-Jing Zhang Chem. Commun. , 2024 DOI [link] Reversible covalent electrophiles with the advantages of both reversible and covalent interactions receive much attention in the fields of chemical biology and medicinal chemistry. Here, we report two electron-deficient olefins activated by amide and ester, amide-substituted acrylamide and methyl ester-substituted acrylamide, targeting thiols in a reversible covalent manner.
Speaker: Simran Kaur, Co-founder & CEO at Tattva.Health
AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!
A major new study reveals that carbon dioxide emissions from forest fires have surged by 60 percent globally since 2001, and almost tripled in some of the most climate-sensitive northern boreal forests.
Vyalev’s clearance is the second victory for AbbVie in Parkinson’s this year, following an April readout for a drug acquired through its Cerevel buyout.
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Vyalev’s clearance is the second victory for AbbVie in Parkinson’s this year, following an April readout for a drug acquired through its Cerevel buyout.
THURSDAY, Oct. 17, 2024 -- Folks who want solid protection during the cold and flu season should get the influenza vaccine now, the U.S. Food and Drug Administration says. The ideal time to get the flu vaccine is by the end of October, the FDA said.
Eric M. Merten and John D. Sears and Tina M. Leisner and P. Brian Hardy and Anirban Ghoshal and Mohammad Anwar Hossain and Kesatebrhan Haile Asressu and Peter J. Brown and Edwin G. Tse and Michael A. Stashko and Kelin Li and Jacqueline L. Norris-Drouin and Laura E. Herring and Angie L. Mordant and Thomas S. Webb and Christine A. Mills and Natalie K.
According to new research, men and women rely on different biological systems for pain relief, which could help explain why our most powerful pain medications are often less effective in women.
Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.
The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven
WEDNESDAY, Oct. 16, 2024 -- The number of U.S. children who suffer seizures after swallowing prescription medications or illicit drugs has doubled in recent years, a new study finds. Drug poisonings among kids resulting in seizures increased from.
Researchers have engineered bacteria as personalized cancer vaccines that activate the immune system to specifically seek out and destroy cancer cells.
Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.
WEDNESDAY, Oct. 16, 2024 -- Most Americans 50 and older don’t place much trust in health advice generated by artificial intelligence, a new survey finds.About 74% of middle-aged and senior Americans would have very little to no trust in health info.
Sang Joon Won, Yuxiang Zhang, Christopher J. Reinhardt,Lauren M. Hargis, Nicole S. MacRae,Kristen E. DeMeester,Evert Njomen,Jarrett R. Remsberg,Bruno Melillo, Benjamin F. Cravatt, Michael A. Erb Molecular Cell, 2024 [link] Pioneer transcription factors (TFs) bind to and open closed chromatin, facilitating engagement by other regulatory factors involved in gene activation or repression.
A recent study found that good physical fitness from childhood to adolescence is linked to better mental health in adolescence. These results are significant and timely, as mental health problems are currently a major societal challenge, affecting up to 25%--30% of young people. These findings suggest that improving physical fitness from childhood can help prevent mental health problems.
The agency agreed in court to allow compounding companies to continue producing copycat versions of Lilly’s fast-selling medicines while it reevaluates its recent decision to declare the drugs back in supply.
Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.
FRIDAY, Oct. 18, 2024 -- A global real-world study of the vaccine for respiratory syncytial virus (RSV) finds it offers folks aged 60 and over 80% protection against severe illness and/or hospitalization.With U.S. vaccination rates falling, "I.
Weizhi Weng, Ping Zhang, and Zhengying Pan Journal of the American Chemical Society 2024 DOI: 10.1021/jacs.4c06459 Naturally, kinases exert their activities in a highly regulated fashion. A number of ingenious approaches have been developed to artificially control kinase activity by external stimuli, such as the incorporation of unnatural amino acids or the fusion of additional protein domains; however, methods that directly modulate endogenous kinases in native cells are lacking.
The French drugmaker will invest 300 million euros into a new entity that will develop lead isotope-based therapies for cancer under the Orano Med brand.
Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic
THURSDAY, Oct. 17, 2024 -- An off-label clot-busting drug appears to work slightly better in treating stroke patients than an approved medication, a new review finds. The clot-buster tenecteplase is associated with a slightly higher likelihood of.
Weizhi Weng, Ping Zhang, and Zhengying Pan Journal of the American Chemical Society 2024 DOI: 10.1021/jacs.4c06459 Naturally, kinases exert their activities in a highly regulated fashion. A number of ingenious approaches have been developed to artificially control kinase activity by external stimuli, such as the incorporation of unnatural amino acids or the fusion of additional protein domains; however, methods that directly modulate endogenous kinases in native cells are lacking.
The more men are concerned about appearing masculine, the less likely they will forgive a co-worker for a transgression such as missing an important meeting, a study has found. What's more, such men are also more likely seek revenge or avoid the transgressor, which contributes to an unhealthy and less effective work environment.
The hold, which was made in response to a serious adverse event report, could impact the company’s plans to start a Phase 3 trial of a combination shot for COVID-19 and influenza.
FRIDAY, Oct. 18, 2024 -- Intrauterine devices (IUDs) may raise the chances of a breast cancer diagnosis for women who use the hormonal birth control method, but that risk remains low, new research finds.In the study of 150,000 Danish women.
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