Science Daily: Pharmacology News
OCTOBER 17, 2024
A new study reveals how the duplication of the salivary amylase gene may not only have helped shape human adaptation to starchy foods, but may have occurred as far back as more than 800,000 years ago, long before the advent of farming.
Drug Discovery Today
OCTOBER 15, 2024
Pioneer Group, the specialist life science infrastructure and venture-building company, welcomed 425 school children from 29 schools to eight of its sites across the UK last week to mark Ada Lovelace Day, an international celebration of the achievements of women in STEM.
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BioPharma Drive: Drug Pricing
OCTOBER 17, 2024
Vyalev’s clearance is the second victory for AbbVie in Parkinson’s this year, following an April readout for a drug acquired through its Cerevel buyout.
Chemical Biology and Drug Design
OCTOBER 13, 2024
This review will provide a comprehensive analysis and outlines various state-of-the-art AI/ML techniques to the readers with their framework applications. This review also highlights the challenges in this field which need to be addressed for further successes in pharmaceutical applications. ABSTRACT The technological revolutions in computers and the advancement of high-throughput screening technologies have driven the application of artificial intelligence (AI) for faster discovery of drug mole
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Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.
Science Daily: Pharmacology News
OCTOBER 17, 2024
A new vaccine provides hope for treating and even preventing the highly contagious and difficult-to-treat Clostridioides difficile infection, more commonly known as C. difficile or C. diff. In animal models, this first mRNA-LNP C. difficile vaccine was found to protect against C. difficile first-time infections and relapsing infections by inducing a robust immune response, promote clearance of existing C. diff bacteria from the gut, and even overcome deficits in host immunity to protect animals
Drugs.com
OCTOBER 17, 2024
THURSDAY, Oct. 17, 2024 -- A national recall of meat and poultry has been expanded to include close to 12 million pounds of products that may have been contaminated with listeria, U.S. health officials announced. In addition, the updated recall.
Drug Discovery Digest brings together the best content for drug research and development professionals from the widest variety of industry thought leaders.
Perficient: Drug Development
OCTOBER 15, 2024
This post is the third in a series of four about estimating project hours. Part 1: Sandbagging & Lowballing Part 2: Dependencies & Creep Part 3: Assumptions & Uncertainty Coming Soon: Part 4: The Emotional Conclusion In this third installment of my blog series on project estimates, let’s dive headfirst into the murky waters of assumptions and uncertainty!
Science Daily: Pharmacology News
OCTOBER 16, 2024
According to new research, men and women rely on different biological systems for pain relief, which could help explain why our most powerful pain medications are often less effective in women.
Drugs.com
OCTOBER 17, 2024
THURSDAY, Oct. 17, 2024 -- Folks who want solid protection during the cold and flu season should get the influenza vaccine now, the U.S. Food and Drug Administration says. The ideal time to get the flu vaccine is by the end of October, the FDA said.
BioPharma Drive: Drug Pricing
OCTOBER 17, 2024
The restructuring, which follows clinical setbacks in Alzheimer’s, Parkinson’s and tremor, will also involve the departure of five senior executives.
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Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.
Perficient: Drug Development
OCTOBER 16, 2024
Addressing the Talent Shortage While fears of AI-driven job displacement dominate headlines, the real crisis looming is a $8.5 trillion talent shortage projected by 2030. Much like the famous ‘invisible gorilla’ experiment, where viewers focused on counting basketball passes miss a costumed figure walking through the scene, businesses risk overlooking a crucial element: the Employee Experience (EX).
Science Daily: Pharmacology News
OCTOBER 16, 2024
Researchers have engineered bacteria as personalized cancer vaccines that activate the immune system to specifically seek out and destroy cancer cells.
Drugs.com
OCTOBER 16, 2024
WEDNESDAY, Oct. 16, 2024 -- The number of U.S. children who suffer seizures after swallowing prescription medications or illicit drugs has doubled in recent years, a new study finds. Drug poisonings among kids resulting in seizures increased from.
BioPharma Drive: Drug Pricing
OCTOBER 17, 2024
The French drugmaker will invest 300 million euros into a new entity that will develop lead isotope-based therapies for cancer under the Orano Med brand.
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Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic
Drug Channels
OCTOBER 17, 2024
Today’s guest post comes from Greg Skalicky, President, EVERSANA and Faruk Abdullah, President, Professional Services & Chief Business Officer, EVERSANA Greg and Faruk walk through the marketplace pressures driving Direct-to-Patient commercialization models. They argue that a technology-enabled infrastructure, combined with clinical and reimbursement support specialists, can improve patients' access to new therapies, shorten the time to therapy, and enable better overall clinical outco
Science Daily: Pharmacology News
OCTOBER 16, 2024
With vigorous debate surrounding the health of the monarch butterfly, new research may have answered the biggest question plaguing butterfly researchers. Why are the wintering populations declining while breeding populations are stable?
Drugs.com
OCTOBER 16, 2024
WEDNESDAY, Oct. 16, 2024 -- Most Americans 50 and older don’t place much trust in health advice generated by artificial intelligence, a new survey finds.About 74% of middle-aged and senior Americans would have very little to no trust in health info.
BioPharma Drive: Drug Pricing
OCTOBER 16, 2024
The hold, which was made in response to a serious adverse event report, could impact the company’s plans to start a Phase 3 trial of a combination shot for COVID-19 and influenza.
FDA Law Blog: Biosimilars
OCTOBER 16, 2024
By Sara W. Koblitz — Further talks of the Skinny Label’s demise may be premature, as demonstrated by a new decision from the District Court for the District of Columbia upholding FDA’s interpretation of the “same labeling” provisions of the Hatch-Waxman Amendments. That is not to say that concerns about the induced infringement theory at issue in GSK v.
Science Daily: Pharmacology News
OCTOBER 18, 2024
A species of tropical butterfly with unusually expanded brain structures display a fascinating mosaic pattern of neural expansion linked to a cognitive innovation.
Drugs.com
OCTOBER 18, 2024
FRIDAY, Oct. 18, 2024 -- A global real-world study of the vaccine for respiratory syncytial virus (RSV) finds it offers folks aged 60 and over 80% protection against severe illness and/or hospitalization.With U.S. vaccination rates falling, "I.
BioPharma Drive: Drug Pricing
OCTOBER 14, 2024
The deal would hand Lundbeck a treatment for a series of rare brain disorders that could, by the company's estimates, become a blockbuster product.
Quanticate
OCTOBER 15, 2024
As clinical trials grow in complexity, the volume of data collected and the need for advanced statistical techniques, such as Bayesian Analysis and Multiple Imputation (MI), continue to expand. These methods require substantial computational power, leading to increased processing times that can delay critical analysis and reporting stages. Such delays pose challenges in meeting tight project timelines, especially when multiple analyses or quality control (QC) tasks must be performed on large dat
Science Daily: Pharmacology News
OCTOBER 17, 2024
A new study opens the door to cutting-edge solutions that could contribute to the realization of a system capable of processing quantum information in a simple yet powerful way. The work presents a method for manipulating the photonic states of light in a never-before-seen way, offering greater control over the evolution of photon propagation. This control makes it possible to improve the detection and number of photon coincidences, as well as the efficiency of the system.
Drugs.com
OCTOBER 17, 2024
THURSDAY, Oct. 17, 2024 -- An off-label clot-busting drug appears to work slightly better in treating stroke patients than an approved medication, a new review finds. The clot-buster tenecteplase is associated with a slightly higher likelihood of.
BioPharma Drive: Drug Pricing
OCTOBER 16, 2024
The pharma’s lawsuit focuses on scientific work that helped clear the path for creating mRNA vaccines to fight the COVID-19 pandemic.
Drug Channels
OCTOBER 15, 2024
A new survey of plan sponsors sheds light on their satisfaction with transparency at large and small pharmacy benefit managers (PBMs). As you will see, clients remain slightly more satisfied with the perceived transparency of smaller PBMs compared with the Big Three PBMs—CVS Caremark, Express Scripts, and Optum Rx. However, plan sponsors are dissatisfied with transparency about how both large and small PBMs make money.
Science Daily: Pharmacology News
OCTOBER 17, 2024
A major new study reveals that carbon dioxide emissions from forest fires have surged by 60 percent globally since 2001, and almost tripled in some of the most climate-sensitive northern boreal forests.
Drugs.com
OCTOBER 17, 2024
THURSDAY, Oct. 17, 2024 -- Doctors might be overprescribing sedatives to stroke survivors, a new study warns. About 5% of people are prescribed a benzodiazepine following a stroke, to help calm anxiety and improve sleep, researchers found.
BioPharma Drive: Drug Pricing
OCTOBER 18, 2024
Detailed data from a Phase 2b/3 study of Merck’s treatment clesrovimab should support the company’s efforts to win approval by the 2025-2026 season.
Broad Institute
OCTOBER 15, 2024
#WhyIScience Q&A: A microbiologist and immunologist finds links between our own microbes and disease mechanisms By Ari Navetta October 15, 2024 Breadcrumb Home #WhyIScience Q&A: A microbiologist and immunologist finds links between our own microbes and disease mechanisms Eric Brown discusses finding purpose in the unpredictability of research and his personal connection to his work.
Science Daily: Pharmacology News
OCTOBER 17, 2024
Microorganisms do not just colonize the body of mammals during infections. Billions of microbes can be found on and in healthy humans and animals at any given time, communicating with each other via chemical signals and thus influencing their health. In two studies, researchers have now conducted a detailed study of the microbiome, i.e. the totality of all microorganisms, in humans and zoo animals.
Drugs.com
OCTOBER 18, 2024
FRIDAY, Oct. 18, 2024 -- A global real-world study of the vaccine for respiratory syncytial virus (RSV) finds it offers folks aged 60 and over 80% protection against severe illness and/or hospitalization. With U.S. vaccination rates falling, "I.
BioPharma Drive: Drug Pricing
OCTOBER 14, 2024
The approval of Hympavzi Friday was a dose of good news for Pfizer, which is dealing with research setbacks and a challenge from an activist investor.
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