Science Daily: Pharmacology News
OCTOBER 30, 2024
In a new study, researchers discovered that tweaking the texture of any surface and adding a thin layer of graphene oxide prevents 100% of frost from forming on surfaces for one week or potentially even longer. This is 1,000 times longer than current, state-of-the-art anti-frosting surfaces.
Nvidia Developer: Drug Discovery
OCTOBER 30, 2024
The integration of AI in drug discovery is revolutionizing the way researchers approach the development of new treatments for various diseases. Traditional. The integration of AI in drug discovery is revolutionizing the way researchers approach the development of new treatments for various diseases. Traditional methods are often time-consuming and costly, with the process of bringing a new drug to market taking up to 15 years and costing between $1–2B.
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Broad Institute
OCTOBER 29, 2024
New drug triggers rapid cell death in cancer models By Karen Zusi-Tran October 29, 2024 Breadcrumb Home New drug triggers rapid cell death in cancer models BRD-810 inhibits the MCL1 protein and reactivates apoptosis in tumor cells, displaying therapeutic potential in animal models. By Karen Zusi-Tran October 29, 2024 Credit: National Cancer Institute Human cells with acute myelocytic leukemia (AML) in the pericardial fluid.
BioPharma Drive: Drug Pricing
NOVEMBER 1, 2024
The Phase 3 findings position semaglutide to become the first drug of its kind for the liver disease. But they also confirm GLP-1s aren't a "silver bullet" for MASH, one analyst argued.
Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.
The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven
Science Daily: Pharmacology News
OCTOBER 31, 2024
Children who experienced sugar restrictions during their first 1,000 days after conception had up to 35% lower risk of developing type 2 diabetes and as much as 20% less risk of hypertension as adults. The researchers used contemporary data from the U.K. Biobank, a database of medical histories and genetic, lifestyle and other disease risk factors, to study the effect of those early-life sugar restrictions on health outcomes of adults conceived in the U.K. just before and after the end of wartim
Drugs.com
OCTOBER 30, 2024
WEDNESDAY, Oct. 30, 2024 -- In the highest tally ever recorded for tuberculosis cases, the World Health Organization reported Tuesday that over 8 million people worldwide were diagnosed with the lung disease last year.Of that number, 1.25 million.
Drug Discovery Digest brings together the best content for drug research and development professionals from the widest variety of industry thought leaders.
BioPharma Drive: Drug Pricing
OCTOBER 29, 2024
Daniel Quirk, an immunology and neuroscience executive at Bristol Myers Squibb, will be Biogen’s next chief medical officer, while Robin Kramer will replace retiring CFO Michael McDonnell.
Science Daily: Pharmacology News
OCTOBER 30, 2024
A new study unveils a surprising discovery: a substantial amount of meltwater is temporarily stored within the Greenland Ice Sheet during summer months. For the first time, an international group of researchers was able to quantify meltwater with positioning data. The finding challenges current models of how ice sheets contribute to global sea level rise.
Drugs.com
NOVEMBER 1, 2024
FRIDAY, Nov. 1, 2024 -- The GLP-1 drug semaglutide can help obese people manage debilitating knee arthritis, a new trial has found.People who received weekly injections of semaglutide -- the active agent in the diabetes drug Ozempic and the.
Perficient: Drug Development
OCTOBER 29, 2024
The 2024 InsureTech Connect (ITC) conference was truly exhilarating, with key takeaways impacting the insurance industry. Each year, it continues to improve, offering more relevant content, valuable industry connections, and opportunities to delve into emerging technologies. This year’s event was no exception, showcasing the importance of personalization to the customer, tech-driven relationship management, and AI-driven underwriting processes.
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Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.
BioPharma Drive: Drug Pricing
OCTOBER 30, 2024
All doses of the two drugs are now listed as available in the U.S., per an FDA database, although the company cautioned patients may still experience "variability" filling their prescriptions.
Science Daily: Pharmacology News
OCTOBER 30, 2024
New research in our Milky Way has revealed a neutron star that rotates around its axis at an extremely high speed. It spins 716 times per second, making it one of the fastest-spinning objects ever observed.
Drugs.com
NOVEMBER 1, 2024
FRIDAY, Nov. 1, 2024 -- Sleep apnea appears to increase a person's odds of developing dementia, a new study finds.The effect seems stronger among women compared to men, noted a research team from the University of Michigan. Luckily, there are.
Drug Target Review
OCTOBER 30, 2024
Imagine being able to create an in vitro replica of a diseased organ to study the molecular mechanism underlying the illness. Now take a step further: envision testing drugs in these organoids to identify the ones that can treat disease safely and effectively without needing to run expensive clinical trials first. Further still, think about implanting these mini organs into the patient to restore lost function.
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Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.
BioPharma Drive: Drug Pricing
OCTOBER 30, 2024
Archon Biosciences, co-founded by the winner of the 2024 Nobel Prize in Chemistry, emerged from stealth Wednesday with $20 million in seed capital.
Science Daily: Pharmacology News
OCTOBER 30, 2024
Chronic, low-level lead poisoning is a major risk factor for cardiovascular disease in adults and cognitive deficits in children, even at levels previously thought to be safe, Low-level lead poisoning is a risk factor for preterm. Annually 5.5 million deaths from cardiovascular disease attributed to low-level lead poisoning; accounts for a loss of 765 million IQ points in children.
Drugs.com
OCTOBER 29, 2024
TUESDAY, Oct. 29, 2024 -- Artificial intelligence might be able to help doctors detect the prostate cancers most likely to be life-threatening to men, a new study suggests. An AI program successfully identified and outlined 85% of the most.
FDA Law Blog: Biosimilars
OCTOBER 27, 2024
By Deborah L. Livornese & John W.M. Claud & Charles D. Snow — On October 21, 2024, the Alliance for Natural Health USA (“ANH”), and Meditrend Inc., a homeopathic drug company, filed a complaint on behalf of the homeopathic drug industry against FDA in the District Court for the District of Columbia (“D.D.C.”). This lawsuit presents an interesting reading of the statute at issue, one that is diametrically opposed to that of FDA.
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Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic
BioPharma Drive: Drug Pricing
OCTOBER 31, 2024
The biotech expects three Phase 2 readouts in urticaria and eczema over the next two years, and will keep its “options open” regarding an IPO, its CEO said.
Science Daily: Pharmacology News
OCTOBER 31, 2024
Researchers have created the first blueprint of the human spliceosome, the most complex and intricate molecular machine in human biology. The vast majority of human genes -- more than nine in ten -- are edited by the spliceosome. The sheer number of components involved has meant the scientific feat took more than a decade to complete. The research reveals many new drug targets that could benefit a wide spectrum of diseases including most types of cancer, neurodegenerative conditions and genetic
Drugs.com
OCTOBER 29, 2024
TUESDAY, Oct. 29, 2024 -- Middle-aged folks facing a colon cancer screening now have a blood test they can choose over a standard colonoscopy.However, the blood test isn't as effective as colonoscopy at detecting and preventing colon cancer, a new.
Broad Institute
OCTOBER 28, 2024
New machine learning-based single-cell search engine makes cell annotation faster, more efficient By Corie Lok October 28, 2024 Breadcrumb Home New machine learning-based single-cell search engine makes cell annotation faster, more efficient In a Q&A, machine learning expert Mehrtash Babadi introduces Cell Annotation Service, a search engine for single-cell data that he and his group have developed for biologists.
BioPharma Drive: Drug Pricing
OCTOBER 30, 2024
The British pharma’s experience during the third quarter mirrored that of rival Pfizer, which also reported lower sales of its competing RSV shot.
Science Daily: Pharmacology News
OCTOBER 31, 2024
Scientists investigating animal viruses with potential to infect humans have identified a critical protein that could enable spillover of a family of organisms called arteriviruses. In a new study, researchers identified a protein in mammals that welcomes arteriviruses into host cells to start an infection. The team also found that an existing monoclonal antibody that binds to this protein protects cells from viral infection.
Drugs.com
OCTOBER 28, 2024
MONDAY, Oct. 28, 2024 -- Most thyroid cancers are slow-moving and, if caught early, curable. But some patients can present with what's known as an anaplastic thyroid carcinoma (ATC) -- a rare and very aggressive tumor with a very poor prognosis.
Quanticate
OCTOBER 27, 2024
The development of investigational new drugs (INDs) involves performing clinical trials (or studies) to assess the safety and efficacy of the IND in humans. These trials are usually classified into 4 phases of development (Phase 1 to 4), with each potentially lasting for several years. Successful completion of each phase and approval by the appropriate regulatory authority or authorities (the European Medicines Agency [EMA] in the European Union, Food and Drug Administration [FDA] in the United
Drug Patent Watch
OCTOBER 27, 2024
A troubling trend has emerged in recent years, leaving both healthcare providers and patients grappling with an unexpected challenge: the persistent shortage of generic drugs in hospitals. This issue has far-reaching consequences, affecting patient care, hospital operations, and the broader healthcare system.
Science Daily: Pharmacology News
OCTOBER 28, 2024
Buildup of a protein called filamentous actin, or F-actin, in the brain inhibits the removal of cellular wastes, including DNA, lipids, proteins and organelles. The resulting accumulation of waste diminishes neuronal functions and contributes to cognitive decline. By tweaking a few very specific genes in the neurons of aging fruit flies, the researchers prevented F-actin buildup, maintained cellular recycling and extended the healthy lifespan of fruit flies by approximately 30%.
Drugs.com
OCTOBER 28, 2024
MONDAY, Oct. 28, 2024 -- More than 20% of people in the continental United States might have drinking water contaminated with “forever chemicals,” a new study suggests.Between 75 and 95 million Americans rely on groundwater that contains det.
Drug Channels
NOVEMBER 1, 2024
Today’s guest post comes from Kimberley Chiang, Vice President of Biopharma Commercial Solutions at CoverMyMeds Kimberley highlghts the crucial roles of field reimbursement managers in removing access and reimbursement barriers. She then identifies the keys to successful implementation of field reimbursement services. To learn more, register for CoverMyMeds' November 13, 2024, webinar: Specialty Therapies & Field Reimbursement Services: Driving Better Outcomes for Brands and Patients.
LifeSciVC
OCTOBER 28, 2024
Today’s market likes products. Platforms aren’t in vogue anymore. Investors, especially in the public markets, only want late stage de-risked assets. Pharma only seems to be buying these kinds of asset. VCs need to focus on clinical stage companies. Or so the conventional wisdom goes in the equity capital markets these days. While it may be the prevailing wind, an innovation ecosystem that allocates capital only to later stage assets risks exhibiting a rather unhealthy blend of investment myopia
Science Daily: Pharmacology News
OCTOBER 30, 2024
A new study finds that up to 215 million hectares of land (an area larger than Mexico) in humid tropical regions around the world has the potential to naturally regrow. That much forest could store 23.4 gigatons of carbon over 30 years and also have a significant impact on concerns like biodiversity loss and water quality. The study showed that more than half of the area with strong potential for regrowth was in five countries: Brazil, Mexico, Indonesia, China, and Colombia.
Drugs.com
OCTOBER 31, 2024
THURSDAY, Oct. 31, 2024 -- Whooping cough is on the rise in the United States, with cases surging across the nation.It’s important to remember that whooping cough, also known as pertussis, can impact adults as well as kids, according to Infectious D.
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