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THURSDAY, Nov. 14, 2024 -- Over 600,000 people worldwide die from mosquito-borne malaria each year, with the majority of these deaths happening among children under 5.Now, there's troubling news that the malaria parasite may be gaining resistance.
At an event hosted by BioPharma Dive, drugmaker executives and investors discussed the importance of focus, smart spending and maintaining lines of sight to the clinic.
More time spent sitting, reclining or lying down during the day may increase the risk of cardiovascular disease (CVD) and death, according to a new study. More than roughly 10-and-a-half hours of sedentary behavior per day was significantly linked with future heart failure (HF) and cardiovascular (CV) death, even among people meeting recommended levels of exercise.
The ability to compare the sequences of multiple related proteins is a foundational task for many life science researchers. This is often done in the form of a. The ability to compare the sequences of multiple related proteins is a foundational task for many life science researchers. This is often done in the form of a multiple sequence alignment (MSA), and the evolutionary information retrieved from these alignments can yield insights into protein structure, function, and evolutionary history.
Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.
The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven
FRIDAY, Nov. 15, 2024 -- Waning vaccine coverage has fueled a 20% spike in measles cases worldwide, with 10.3 million people struck by the preventable illness in 2023, health officials reported Wednesday."Inadequate immunization coverage globally.
Negative drug results cost AbbVie billions of dollars in market value and convinced analysts that Bristol Myers had placed a better bet in buying Karuna Therapeutics.
Researchers have developed PanoRadar, a new tool to give robots superhuman vision by transforming simple radio waves into detailed, 3D views of the environment.
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Drug Discovery Digest brings together the best content for drug research and development professionals from the widest variety of industry thought leaders.
Researchers have developed PanoRadar, a new tool to give robots superhuman vision by transforming simple radio waves into detailed, 3D views of the environment.
WEDNESDAY, Nov. 13, 2024 -- The blockbuster GLP-1 drug semaglutide (Ozempic, Wegovy) could curb drinking for people battling alcohol use disorder, helping them to avoid crises that require hospitalization, new research shows. Numerous studies had.
The company is paying China-based biotech LaNova Medicines $588 million for the type of dual-pronged antibody drug that recently bested Keytruda in a clinical trial.
How much land, water, and other resources does our lifestyle require? And how can we adapt this lifestyle to stay within the limits of what the Earth can give? A new article tackles these questions.
Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.
FRIDAY, Nov. 15, 2024 -- An experimental vaccine has shown promise in protecting against the sexually transmitted disease chlamydia, researchers report.Lab mice given the vaccine were able to rapidly clear subsequent chlamydia infections, and were.
A key regulatory committee sided against the drug this summer. But an appeal from Eisai appears to have worked, teeing Leqembi up for authorization in a major market.
Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.
A series of chromone derivatives were designed and synthesized. We established a NOX4 overexpression model using the NRK-49F and identified compound 14m as highly active through the assessment of intracellular ROS levels. This investigation positions 14m as a noteworthy NOX4 inhibitor, shedding light on its regulatory role in renal fibroblasts. ABSTRACT Nicotinamide adenine dinucleotide phosphate oxidase 4 (NOX4) has emerged as a promising target for developing drugs to tackle renal fibrosis.
MONDAY, Nov. 11, 2024 -- The weight-loss drug Ozempic can help reduce stroke patients’ risk of a heart attack or death, a new study says.GLP-1 weight-loss drugs like Ozempic or SGLT2 diabetes medications like Jardiance or Farxiga both helped p.
Biotheus’ antibody drug targets PD-L1 and VEGF, a design that’s high on drugmakers’ radars after the success of Summit Therapeutics’ ivonescimab over Keytruda.
A genomic test developed by researchers to rapidly detect almost any kind of pathogen -- virus, bacteria, fungus or parasite -- has proved successful after a decade of use.
Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic
It is hard to ignore some of the most pressing, long-term trends driving the push to accelerate innovation and progress in drug development. From an aging population increasing health care demand to urgent, unmet medical needs, there are clear drivers to advance safe and effective medicines to patients faster than ever. According to the United Nation’s 2024 World Population Prospects data, the global population of those 65 years old and over will grow from 0.8 billion in 2023 to 1.2 billion in 2
FRIDAY, Nov. 15, 2024 -- There have been a slew of studies recently supporting the notion that the same mechanisms that help folks lose weight with Ozempic and its kin also work to curb problem drinking.Now, a new study out of Britain adds to that.
Researchers have found that under certain conditions, a laser beam can act like an opaque object and cast a shadow, opening new possibilities for technologies that could use a laser beam to control another laser beam.
Healthcare leaders are engaging us in a variety of discussions to explore intelligent automation’s role for complex business challenges, ranging from efforts to enhance consumer trust and use artificial intelligence (AI) in effective ways, to navigating change that comes with prior authorization mandates. This series shares key insights coming from those discussions.
TUESDAY, Nov. 12, 2024 -- Beta blockers are go-to meds for many people who've survived a heart attack.However, new Swedish research has found that they might not be needed for heart attack survivors whose hearts have retained a normal pumping.
A 'one of a kind' fossil discovery could transform our understanding of how the unique brains and intelligence of modern birds evolved, one of the most enduring mysteries of vertebrate evolution.
In an era where clinical trials are increasingly global, it’s more imperative than ever to leverage international expertise. Data and safety monitoring boards (DSMBs), also known as data monitoring committees (DMCs), play a critical role in overseeing a clinical trial’s safety and efficacy. These independent committees are entrusted with the task of safeguarding study participant’s interests while ensuring the trial’s scientific integrity.
FRIDAY, Nov. 15, 2024 -- Time spent sitting, reclining or lying down during the day could increase a person’s risk of heart disease and death, a new study warns.More than 10 and a half hours of sedentary behavior is significantly linked with future.
Combined with network pharmacology and experimental verification, this study found that platycodin D and luteolin in Jiegeng ( Platycodonis Radix ) may regulate inflammation through the IL-17 signaling pathway to treat influenza virus pneumonia. ABSTRACT This study aimed to explore the pathogenesis of platycodin D and luteolin, which are both active components in Jiegeng ( Platycodonis Radix ), in the treatment of influenza virus pneumonia through network pharmacology analysis combined with expe
Could social bonds be the key to human big brains? A study of the fossil teeth of early Homo from Georgia dating back 1.77 million years reveals a prolonged childhood despite a small brain and an adulthood comparable to that of the great apes. This discovery suggests that an extended childhood, combined with cultural transmission in three-generation social groups, may have triggered the evolution of a large brain like that of modern humans, rather than the reverse.
Effective management of drug patent portfolios is crucial for pharmaceutical companies to maintain market exclusivity, protect revenue streams, and drive innovation. A robust patent strategy aligned with business goals is essential for maximizing value and staying competitive in the pharmaceutical landscape.
FRIDAY, Nov. 15, 2024 -- AI can’t yet help doctors improve their ability to diagnose complex conditions, a sobering new study has found.Doctors had about the same diagnostic accuracy whether or not they were using ChatGPT Plus, according to results.
By Sarah Wicks & James E. Valentine — The U.S. Food and Drug Administration (FDA) plays a pivotal role in fostering the development of treatments for rare diseases through its Orphan Products Grants Program. Each year, FDA selects a limited number of clinical trials to fund to help sponsors pursue development of medical products for rare diseases and advance their field.
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