Broad Institute

JUNE 18, 2024

Simple test for flu could improve diagnosis and surveillance By Allessandra DiCorato June 18, 2024 Breadcrumb Home Simple test for flu could improve diagnosis and surveillance A low-cost CRISPR-based paper strip test distinguishes between influenza types and can be reprogrammed to recognize different viruses including the H5N1 bird flu virus. By Allessandra DiCorato June 18, 2024 Credit: Jon Arizti-Sanz SHINE, a rapid diagnostic test developed by Pardis Sabeti's lab in 2020, uses paper strips an

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Science Daily: Pharmacology News

JUNE 20, 2024

Scientists have discovered a new cause of why people who lack a specific blood group are genetically predisposed to be overweight or obese.

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BioPharma Drive: Drug Pricing

JUNE 17, 2024

One expert described trial results presented at EULAR last week as “unprecedented.” But reports of relapses in some patients drew questions about the therapies’ ultimate potential.

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Drugs.com

JUNE 20, 2024

THURSDAY, June 20, 2024 -- Seven different kinds of microplastics have been discovered in human penises for the first time.The tiny fragments, formed when plastic products break down in the environment, were found in four of five samples of penis.

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Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

Treatment

Drug Patent Watch

JUNE 20, 2024

In the high-stakes world of pharmaceuticals, patents play a pivotal role in safeguarding intellectual property and ensuring a return on investment for drug developers. The journey of a drug patent is a complex and intricate one, spanning from the initial filing to its eventual expiry.

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Science Daily: Pharmacology News

JUNE 20, 2024

Adults with a history of low back pain went nearly twice as long without a recurrence of their back pain if they walked regularly, a world-first study has found.

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Drugs.com

JUNE 18, 2024

TUESDAY, June 18, 2024 -- Patients are less likely to fill prescriptions for the overdose-reversing drug naloxone when they have to shell out more at the pharmacy, a new study finds.Naloxone (also known by the brand name Narcan) is a critical.

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Pharmacy Drugs 115

Drug Patent Watch

JUNE 19, 2024

In the ever-evolving pharmaceutical landscape, savvy businesses are constantly on the lookout for untapped markets and lucrative opportunities. One area that has garnered significant attention is the realm of low-competition generic drugs.

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Science Daily: Pharmacology News

JUNE 17, 2024

New research shows when animals are fed a diet high in saturated fat for nine weeks, their gut bacteria change in ways that influence brain chemicals and fuel anxiety.

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Research 138

BioPharma Drive: Drug Pricing

JUNE 20, 2024

Researchers recommended Gilead end testing early as lenacapavir proved 100% effective in protecting cisgender women in the Phase 3 trial.

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Trials Drugs Research 128

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Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

Clinical Trials

Drugs.com

JUNE 20, 2024

THURSDAY, June 20, 2024 -- A Colombian family’s genetics are shining a spotlight on a gene that might help protect people from the ravages of Alzheimer’s disease.About 1,200 out of 6,000 family members carry a genetic variant called the “Paisa mutat.

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Drug Patent Watch

JUNE 17, 2024

The article “The devil is in the divisional: an analysis of divisional patents, deadlines, declarations and suggestions for future practice” by Mieke Filler provides a comprehensive analysis of the strategic use of divisional patents in the pharmaceutical sector to delay generic and biosimilar market entry.

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Biosimilars Pharmaceuticals Marketing 110

Science Daily: Pharmacology News

JUNE 17, 2024

The relationship between mother and child may offer clues to the mystery of why humans live longer than expected for their size -- and shed new light on what it means to be human -- according to a new study.

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BioPharma Drive: Drug Pricing

JUNE 20, 2024

The agency has lifted a partial trial suspension based on one-year data showing PTC’s pill suppressed a key protein associated with the disorder.

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Trials Disease FDA 124

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Clinical Trials

Drugs.com

JUNE 19, 2024

WEDNESDAY, June 19, 2024 -- Only a third of outpatient mental health facilities offer medications essential for treating opioid addiction, a new study finds.Standard care for treating people with opioid use disorder involves drugs like.

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Drug Patent Watch

JUNE 17, 2024

Pharmaceutical companies employ various strategies to extend the commercial life and patent protection of successful drugs. Here are some key approaches with examples: New Formulations One common strategy is to develop and patent new formulations of the existing drug compound to provide benefits like reduced dosing frequency, easier administration, improved bioavailability, or reduced side effects.

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Science Daily: Pharmacology News

JUNE 18, 2024

Scientists discovered that Neolamprologus savoryi fish use punishment to encourage offspring to cooperate in brood care, revealing advanced cognitive abilities previously thought unique to higher vertebrates. This study highlights that punishment for promoting cooperation exists beyond human societies, prompting a reevaluation of animal intelligence.

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BioPharma Drive: Drug Pricing

JUNE 20, 2024

Interim study data suggest the Danish drugmaker can remain in the race to develop new kinds of weight loss drugs as doctors seek alternatives to the now dominant GLP-1s.

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Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

Clinical Trials

Drugs.com

JUNE 21, 2024

FRIDAY, JUNE 21, 2024 -- Both the World Health Organization and Eli Lilly Co. warned Thursday that consumers should avoid fake versions of weight-loss drugs that are circulating in numerous countries.The WHO warning said that the international.

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Drug Patent Watch

JUNE 18, 2024

Branded generics are generic drugs that are marketed under a brand name by the manufacturer. These products contain the same active ingredients as their brand-name counterparts but are typically sold at a lower price point. Branded generics can be an attractive option for both consumers and pharmaceutical companies, offering cost savings while leveraging brand recognition.

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Science Daily: Pharmacology News

JUNE 18, 2024

A single large population of healer cells, called regulatory T cells, is whizzing around our body -- not multiple specialist populations restricted to specific parts of the body as previously thought. These cells shut down inflammation and repair the collateral damage to cells caused after our immune system has responded to injury or illness. Tests, in mice, of a drug developed by the researchers showed that regulatory T cells can be attracted to specific body parts, boosted in number, and activ

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BioPharma Drive: Drug Pricing

JUNE 17, 2024

Elevate precision medicine: dose optimization and immune monitoring through advanced liquid biopsies.

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Drugs.com

JUNE 21, 2024

FRIDAY, June 21, 2024 -- A medication used to manage type 2 diabetes has been found effective in treating sleep apnea.The worldwide clinical trial demonstrates that tirzepatide significantly lowers breathing interruptions during sleep, a key.

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Clinical Trials Trials Drugs 111

Drug Patent Watch

JUNE 18, 2024

This chart shows the drugs with the most patents in New Zealand. Patents must be filed in each country (or, in some cases regional patent office) where patent protection is desired.

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Science Daily: Pharmacology News

JUNE 19, 2024

Roughly one in four U.S. households have soil exceeding the new U.S. Environmental Protection Agency's lead screening levels of 200 parts per million (ppm), halved from the previous level of 400 ppm, a new study found. For households with exposure from multiple sources, the EPA lowered the guidance to 100 ppm; nearly 40% of households exceed that level, the study also found.

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NIOSH Science Blog: Drugs

JUNE 17, 2024

Building strategic partnerships can create solutions to large community safety issues High-risk buildings can be abandoned or condemned structures. These buildings pose hazards to firefighters and communities. This is because many are structurally unsound and not safe for any person to enter. These buildings are commonly a key contributing factor to firefighter line of duty deaths, noted in NIOSH firefighter fatality investigations.

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Drugs.com

JUNE 20, 2024

WEDNESDAY, June 20, 2024 -- Prostate medications might help reduce the risk of a specific type of dementia, a new study suggests.People were less likely to develop Lewy body dementia when taking drugs designed to treat urinary symptoms caused by an.

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Drug Patent Watch

JUNE 17, 2024

A recent whitepaper by Hermann Mucke summarizes the steps to performing an FTO for drug repurposing: Overview An FtO analysis determines if a new product or process can proceed without infringing third-party intellectual property (IP) rights, especially patents. It is crucial for drug repurposing projects involving known compounds that may still be patent-protected.

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Science Daily: Pharmacology News

JUNE 20, 2024

A wearable health monitor can reliably measure levels of important biochemicals in sweat during physical exercise. The 3D-printed monitor could someday provide a simple and non-invasive way to track health conditions and diagnose common diseases, such as diabetes, gout, kidney disease or heart disease. The monitor was able to accurately monitor the levels of volunteers' glucose, lactate and uric acid as well as the rate of sweating during exercise.

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ASPET

JUNE 20, 2024

Sympathetic hyperinnervation is the leading cause of fatal ventricular arrhythmia (VA) following myocardial infarction (MI). Cardiac mast cells cause arrhythmias directly through degranulation. However, the role and mechanism of mast cell degranulation in sympathetic remodeling remain unknown. We investigated the role of oxytocin (OT) in stabilizing cardiac mast cells and improving sympathetic innervation in rats.

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Drugs.com

JUNE 18, 2024

TUESDAY, June 18, 2024 -- Despite all the grumbling at the time, most Americans now look back upon pandemic-era policies as a good idea, a new poll shows.A majority of Americans see four key pandemic policies as “generally a good idea” in ret.

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Chemical Biology and Drug Design

JUNE 19, 2024

Exploring the transformative impact of large language models (LLMs) in molecular biology and drug development, discussing potential areas of applications and breakthroughs in personalized therapies. LLMs, trained on vast datasets, can decode intricate biological information, from genomic sequences to clinical records, comprehending hidden patterns. While enhancing molecular biology aspects, we also address ethical concerns ensuring responsible application of these models.

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Science Daily: Pharmacology News

JUNE 18, 2024

The rise of advanced artificial intelligence (edge AI) could well mark the beginning of a new era for sustainable agriculture. A recent study proposes a roadmap for integrating this technology into farming practices. The aim? To improve the efficiency, quality and safety of agricultural production, while addressing a range of environmental, social and economic challenges.

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