Science Daily: Pharmacology News
JULY 3, 2024
Scientists have created an anode-free sodium solid-state battery. This brings the reality of inexpensive, fast-charging, high-capacity batteries for electric vehicles and grid storage closer than ever.
BioPharma Drive: Drug Pricing
JULY 2, 2024
The drug, which Lilly will sell as Kinsunla, carries a warning for the risk of a certain kind of imaging abnormality that can be serious in rare cases.
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Drugs.com
JULY 2, 2024
TUESDAY, July 2, 2024 -- Benzodiazepines do not appear to increase dementia risk, but could have subtle long-term effects on brain structure, a new study reports.Researchers found no link between use of the sedative drug and a higher risk of.
Collaborative Drug
JULY 1, 2024
Critical Data Considerations for All Lifecycle Stages of a Biotech Startup
Speaker: Simran Kaur, Co-founder & CEO at Tattva.Health
AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!
Science Daily: Pharmacology News
JULY 1, 2024
Computer scientists have invented a camera mechanism that improves how robots see and react to the world around them. Inspired by how the human eye works, their innovative camera system mimics the tiny involuntary movements used by the eye to maintain clear and stable vision over time.
Drug Discovery Digest brings together the best content for drug research and development professionals from the widest variety of industry thought leaders.
Drugs.com
JULY 2, 2024
TUESDAY, July 2, 2024 -- A new drug to treat Alzheimer's disease was approved by the U.S. Food and Drug Administration on Tuesday. In clinical trials, donanemab (Kisunla) modestly slowed the pace of thinking declines among patients in the early.
Covalent Modifiers
JULY 5, 2024
Nie, D.Y., Tabor, J.R., Li, J. et al. Nat Chem Biol (2024). [link] Targeted protein degradation (TPD) is an emerging therapeutic strategy that would benefit from new chemical entities with which to recruit a wider variety of ubiquitin E3 ligases to target proteins for proteasomal degradation. Here we describe a TPD strategy involving the recruitment of FBXO22 to induce degradation of the histone methyltransferase and oncogene NSD2.
Science Daily: Pharmacology News
JULY 3, 2024
Meet Gaiasia jennyae, the swamp creature with a toilet seat-shaped head. It lived 40 million years before the first dinosaurs, and it was the top predator in its ecosystem.
BioPharma Drive: Drug Pricing
JULY 3, 2024
Multibillion-dollar buyouts from Bristol Myers Squibb and Gilead could yield new drugs for brain and liver diseases, while a new cell therapy may reach market.
Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.
The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven
Drugs.com
JULY 2, 2024
TUESDAY, July 2, 2024 -- Most people addicted to opioids and their loved ones are unaware that their primary care doctor can prescribe a medication to treat the disorder, a new nationwide survey reveals."We've made great strides in making it easier.
Covalent Modifiers
JUNE 29, 2024
Cai, G., Bao, Y., Li, Q. et al. Commun Chem 7 , 144 (2024). [link] Serine–arginine (SR) proteins are splicing factors that play essential roles in both constitutive and alternative pre-mRNA splicing. Phosphorylation of their C-terminal RS domains by SR protein kinases (SRPKs) regulates their localization and diverse cellular activities. Dysregulation of phosphorylation has been implicated in many human diseases, including cancers.
Science Daily: Pharmacology News
JULY 4, 2024
Researchers have discovered several rare types of helper T cells that are associated with immune disorders such as multiple sclerosis, rheumatoid arthritis, and even asthma. The discoveries were made possible by a newly developed technology they call ReapTEC. The new T cell atlas is publicly available and should help in the development of new drug therapies for immune-mediated diseases.
BioPharma Drive: Drug Pricing
JULY 2, 2024
The company claimed Phase 2 study results prove the therapy’s promise treating myasthenia gravis. But shares lost more than a quarter of their value amid questions about the data.
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Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.
Drugs.com
JULY 1, 2024
MONDAY, July 1, 2024 -- You're getting heart surgery, but your surgeon notices a new anomaly that perhaps could be fixed at the same time.That's more likely to happen if you're a man than a woman, new studies find.The findings came as little.
Covalent Modifiers
JUNE 30, 2024
Özge Ünsal, Z. Selin Bacaksiz, Vladislav Khamraev, Vittorio Montanari, Martin Beinborn, and Krishna Kumar ACS Chemical Biology 2024 DOI: [link] The incretin gut hormone glucagon-like peptide-1 (GLP-1) has become a household name because of its ability to induce glucose-dependent insulin release with accompanying weight loss in patients. Indeed, derivatives of the peptide exert numerous pleiotropic actions that favorably affect other metabolic functions, and consequently, such compounds are being
Science Daily: Pharmacology News
JULY 3, 2024
Bone remains found in a Tibetan cave 3,280 m above sea level indicate an ancient group of humans survived here for many millennia.
BioPharma Drive: Drug Pricing
JULY 2, 2024
BARDA will provide Moderna with $176 million to advance late-stage testing of an H5 influenza shot, as health officials monitor animal outbreaks.
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Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.
Drugs.com
JULY 1, 2024
MONDAY, July 1, 2024 -- All Diamond Shruumz edibles have been recalled after the company found high levels of a mushroom toxin in them that may have sickened 39 people in 20 states.The recall includes Diamond Shruumz cones, chocolate bars and.
Covalent Modifiers
JUNE 29, 2024
Bert L. H. Beerkens, Vasiliki Andrianopoulou, Xuesong Wang, Rongfang Liu, Gerard J. P. van Westen, Willem Jespers, Adriaan P. IJzerman, Laura H. Heitman, and Daan van der Es ACS Chemical Biology 2024 DOI: 10.1021/acschembio.4c00210 Small molecular tool compounds play an essential role in the study of G protein-coupled receptors (GPCRs). However, tool compounds most often occupy the orthosteric binding site, hampering the study of GPCRs upon ligand binding.
Science Daily: Pharmacology News
JULY 1, 2024
Researchers have figured out how to turn ordinary white fat cells, which store calories, into beige fat cells that burn calories to maintain body temperature.
BioPharma Drive: Drug Pricing
JULY 1, 2024
The Japan-based drugmaker said its U.S. partner’s “portfolio prioritization efforts” led to the termination. It will refund part of an upfront payment.
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Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic
Drugs.com
JULY 2, 2024
TUESDAY, July 2, 2024 -- U.S. health officials announced Tuesday that the federal government will pay Moderna $176 million to speed development of a pandemic flu vaccine based on mRNA technology.Such a vaccine could be used to treat bird flu in.
Covalent Modifiers
JUNE 29, 2024
Jiho Song , Tianqu Zhai , Heung Sik Hahm , Yuancheng Li , Hui Mao , Xueding Wang , Janggun Jo , Jae Won Chang , Angew. Chem. Int. Ed. 2024 , e202410645. [link] Photoacoustic imaging (PAI) is an emerging modality in biomedical imaging with superior imaging depth and specificity. However, PAI still has significant limitations, such as the background noise from endogenous chromophores.
Science Daily: Pharmacology News
JULY 2, 2024
Saving lives through surgery is no longer exclusive to humans. Scientists now detail how Florida carpenter ants, a common, brown species native to its namesake, selectively treat the wounded limbs of fellow nestmates -- either by wound cleaning or amputation. When experimentally testing the effectiveness of these 'treatments,' not only did they aid in recovery, but the research team found the ants' choice of care catered to the type of injury presented to them.
BioPharma Drive: Drug Pricing
JULY 1, 2024
Under an arrangement with Radionetics, Lilly will have rights to acquire the San Diego biotechnology company for $1 billion.
Drugs.com
JULY 1, 2024
MONDAY, July 1, 2024 (HealthDay news) -- A 14-year study of testicular cancer survivors suggests that a chemotherapy drug could greatly raise patients' long-term odds for hearing loss. The drug in question, cisplatin, has been a mainstay of cancer.
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