ASPET

JULY 26, 2024

Cannabis and its products have been used for centuries for both medicinal and recreational purposes. The recent widespread legalization of cannabis has vastly expanded its use in the United States across all demographics except for adolescents. Meanwhile decades of research have advanced our knowledge of cannabis pharmacology and particularly of the endocannabinoid system with which the components of cannabis interact.

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Research Production 189

Science Daily: Pharmacology News

JULY 26, 2024

Engineering researchers have demonstrated a state-of-the-art hardware device that could reduce energy consumption for artificial intelligent (AI) computing applications by a factor of at least 1,000.

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Research Engineering 133

Drugs.com

JULY 23, 2024

TUESDAY, July 23, 2024 -- The boom in using GLP-1 drugs like Ozempic to treat obesity has resulted in a bust regarding the drugs’ original purpose, which was to treat type 2 diabetes, a new study finds. New prescriptions for these drugs have d.

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Drugs 119

Perficient: Drug Development

JULY 25, 2024

“Double, double toil and trouble,” is a line repeated by the witches in Macbeth as they lay out the ominous prophecies of greatness and dire consequences for the titular character. Macbeth’s ambition envisions a perfect ending though desperate actions and moral weakness ruin it. So too are the misguided actions in pursuit of perfection which can set expectations and pressure that lead to unwanted results.

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Regulations Compliance Production 118

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

Treatment

BioPharma Drive: Drug Pricing

JULY 22, 2024

The company plans to start a late-stage study next year, after a smaller trial found its drug offered “robust and consistent” benefits on communication, cognition and motor function.

Drugs 117

Drugs Trials 117

Science Daily: Pharmacology News

JULY 24, 2024

A study looks at the maximum possible sizes of dinosaurs, using the carnivore, Tyrannosaurus rex, as an example. Using computer modelling, experts produced estimates that T. Rex might have been 70% heavier than what the fossil evidence suggests.

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Drug Target Review

JULY 23, 2024

What inspired you to pursue a career in STEM and can you tell us about how your career journey unfolded? An early introduction to STEM in the classroom sparked my passion for biology and I’m grateful for the exposure to different scientific concepts and contexts at a young age. I wanted to make a tangible impact on the world through biology and was drawn to the challenge of scientific discovery, which led me to pursue a career in the biotech/pharma industry.

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Small Molecule Targeted Protein Degradation Science Disease 115

BioPharma Drive: Drug Pricing

JULY 25, 2024

Some analysts described Sanofi’s pipeline of immune system therapies, which includes more than half a dozen drugs in mid- to late-stage testing, as “underappreciated” by investors, as sales of Dupixent rose over the last quarter.

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Therapies Drugs 113

Science Daily: Pharmacology News

JULY 25, 2024

A noninvasive colorectal cancer screening test that can be done at home could reduce the risk of colorectal cancer death by 33%, according to a new study.

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Drugs.com

JULY 26, 2024

FRIDAY, July 26, 2024 -- Abbott has warned diabetes patients that some of its continuous blood sugar monitoring systems may need to be replaced because of inaccurate readings."Abbott has recently identified a small number of FreeStyle Libre 3.

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Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

Clinical Trials

Codon

JULY 21, 2024

Xander Balwit offers concrete proposals for raising the welfare of animals used in biomedical research for our final article in Issue 03. We’ll be on a brief hiatus for the next few weeks as we prepare for the next Issue! If you’d like to write for us, send a pitch to editors@asimov.com. A hairless and obese rat grimaced at me from behind the glass—its taxidermied gaze fixed on something across the room.

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Research Engineering Disease Science 110

FDA Law Blog: Biosimilars

JULY 23, 2024

By Adrienne R. Lenz, Principal Medical Device Regulation Expert — For several years, FDA has requested that sponsors of drug or biologic led combination products identify essential performance requirements (EPRs) related to the device constituent in their applications. EPRs were usually requested in the context of design controls, although 21 C.F.R. § 820.30 does not use this term.

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FDA Drugs Pharmacokinetics Production 104

Science Daily: Pharmacology News

JULY 22, 2024

Dogs experience emotional contagion from the smell of human stress, leading them to make more 'pessimistic' choices, new research finds. Researchers tested how human stress odors affect dogs' learning and emotional state.

Research 131

Research 131

Drugs.com

JULY 25, 2024

THURSDAY, July 25, 2024 -- The bird flu is now jumping between species of mammals, a step that draws the virus closer to hopping into human beings, a new study warns.Researchers have tracked transmission of avian influenza between dairy cows in.

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Virus 116

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Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

Clinical Trials

Broad Institute

JULY 23, 2024

#WhyIScience Q&A: A mechanical engineer builds microscopes to give new spatial views of cells and tissues By Leah Eisenstadt July 23, 2024 Breadcrumb Home #WhyIScience Q&A: A mechanical engineer builds microscopes to give new spatial views of cells and tissues Lindsey Erion-Barner describes her efforts to develop and share innovative tools in the Spatial Technology Platform By Leah Eisenstadt July 23, 2024 Credit: Allison Colorado, Broad Communications Lindsey Erion-Barner develops and shares

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Engineering Research Science 104

Quanticate

JULY 22, 2024

Throughout the conduct of a clinical trial, ensuring patient safety and maintaining the integrity of the study are vital. This is where, Data Monitoring Committees (DMC) are used to support patient safety and integrity.

Clinical Trials 102

Clinical Trials Trials 102

Science Daily: Pharmacology News

JULY 25, 2024

An experimental drug originally developed to treat cancer may help clear HIV from infected cells in the brain, according to a new study. By targeting infected cells in the brain, drug may clear virus from hidden areas that have been a major challenge in HIV treatment.

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Virus Drugs Treatment 129

Drugs.com

JULY 25, 2024

THURSDAY, July 25, 2025 -- Synthetic antibiotics that attack bacteria in two directions at once could be the solution for combatting antimicrobial-resistant bugs, a new study claims.These dual-action antibiotics, called macrolones, disrupt.

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Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

Clinical Trials

Perficient: Drug Development

JULY 23, 2024

The Importance of Quality Assurance in Software Development The pressure to deliver software quickly and cost-effectively is among the highest priorities of business leaders. However, recent high-profile tech failures serve as stark reminders of the critical importance of robust Quality Assurance (QA) practices. As a leader in digital consulting, we recognize that cutting corners on testing can lead to far-reaching consequences that extend well beyond temporary service disruptions.

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Production Regulations Marketing 102

Drug Patent Watch

JULY 26, 2024

Chiral switching, the practice of developing a single enantiomer from a previously approved racemic drug, has been a significant strategy in the pharmaceutical industry for decades.

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Pharmaceuticals Drugs 97

Science Daily: Pharmacology News

JULY 25, 2024

Engineers discovered that when the aluminum in soda cans is purified and mixed with seawater, the solution produces hydrogen -- which can power an engine or fuel cell without generating carbon emissions. The reaction can be sped up by adding caffeine.

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Engineering 128

Drugs.com

JULY 24, 2024

WEDNESDAY, July 24, 2024 -- Misuse of illicit prescription drugs is falling dramatically among U.S. high school students, a new study says.The percentage of seniors who say they’ve misused prescription drugs in the past year has dropped to 2% in 2.

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Drugs 115

Perficient: Drug Development

JULY 26, 2024

Perficient is thrilled to announce that Amarender Peddamalku has been awarded the prestigious “Most Valuable Professional” (MVP) status in Business Applications by Microsoft for the second time. This achievement is especially significant, highlighting his continued excellence and commitment to the Microsoft community. Amarender Peddamalku serves as the Microsoft Modern Work practice lead and digital transformation leader at Perficient.

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Production 98

BioPharma Drive: Drug Pricing

JULY 22, 2024

Private biotech company acquisitions are on their fastest pace in years, a trend some in the industry say is driven by the abundance of mature, but not yet public, drug startups.

Marketing 101

Marketing Drugs 101

Science Daily: Pharmacology News

JULY 22, 2024

When people are having a conversation, they rapidly take turns speaking and sometimes even interrupt. Now, researchers who have collected the largest ever dataset of chimpanzee 'conversations' have found that they communicate back and forth using gestures following the same rapid-fire pattern.

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Research 129

Drugs.com

JULY 22, 2024

MONDAY, July 22, 2024 -- Daily supplements can slow loss of vision related to late-stage “dry” age-related macular degeneration (AMD), a new study finds.The rate of dry AMD progression into a key eye region slowed by about 55% over an average three.

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National Institute on Drug Abuse: Nora's Blog

JULY 22, 2024

To address the fentanyl crisis, greater access to methadone Is needed area Mon, 07/22/2024 - 12:43 Nora's Blog July 29, 2024 By Nora D. Volkow, National Institute on Drug Abuse Image ©Getty images/ seb_ra Over the past several years, the increasing prevalence of fentanyl in the drug supply has created an unprecedented overdose death rate and other devastating consequences.

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Pharmacy Treatment Community Pharmacies Trials 85

BioPharma Drive: Drug Pricing

JULY 24, 2024

Autobahn’s lead candidate is designed to stimulate thyroid hormone receptors as a way to complement existing antidepressants.

Drugs 111

Drugs 111

Science Daily: Pharmacology News

JULY 22, 2024

In a finding that opens the door to the development of targeted therapies for various muscle disorders, newly published research identifies key mechanisms of skeletal muscle regeneration and growth of muscles following resistance exercise.

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Therapies Research 128

Drugs.com

JULY 26, 2024

FRIDAY, July 26, 2024 -- Older people who avail themselves of the newest shingles vaccine could reap a hidden benefit: A significant drop in their odds of developing dementia. One expert applauded the new findings. "Dementia isn’t an.

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Vaccine 111

Crown Bioscience

JULY 25, 2024

Humanized mice, encompassing human tumors and human immune cells engrafted on immunodeficient mice, have been widely used for many years in immuno-oncology, with developments to improve both the humanization and the translational value central to the next generation of models.

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Drug Patent Watch

JULY 21, 2024

The Patent Trial and Appeal Board (PTAB) is a crucial component of the United States Patent and Trademark Office (USPTO), established in 2012 by the Leahy-Smith America Invents Act (AIA).

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Trials 94

Science Daily: Pharmacology News

JULY 26, 2024

New therapy uses synthetic nanofibers to mimic the natural signaling of a protein that is crucial for cartilage formation and maintenance. Researchers found that intensifying the motion of molecules within the nanofibers led to more components needed for regeneration. After just four hours, the treatment activated the gene expression necessary to generate cartilage.

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Therapies Treatment Research 125