Science Daily: Pharmacology News
OCTOBER 24, 2023
An international coalition of climate scientists says that the Earth's vital signs have worsened beyond anything humans have yet seen, to the point that life on the planet is imperiled.
BioPharma Drive: Drug Pricing
OCTOBER 23, 2023
The trial, which is ongoing in the U.K. and New Zealand, has been on hold in the U.S. since late last year as the FDA sought more details on Verve’s in vivo treatment for heart disease.
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Drugs.com
OCTOBER 25, 2023
WEDNESDAY, Oct. 25, 2023 – Federal regulators are investigating a salmonella outbreak linked to packaged, diced onions that has sickened at least 73 people across 22 states. Fifteen of the illnesses were so bad that people required.
Collaborative Drug
OCTOBER 27, 2023
CDD Exhibiting at the 6th Targeted Protein Degradation Summit, Boston, October 31- November 2.
Speaker: Simran Kaur, Co-founder & CEO at Tattva.Health
AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!
Science Daily: Pharmacology News
OCTOBER 26, 2023
An international study has identified for the first time the optimal number of steps at which most people obtain the greatest benefits, and also shows that the pace at which you walk provides additional benefits.
Drug Discovery Digest brings together the best content for drug research and development professionals from the widest variety of industry thought leaders.
Drugs.com
OCTOBER 27, 2023
FRIDAY, Oct. 27, 2023 -- Federal regulators have sent warning letters to two companies for illegally selling probiotic products for use in preterm infants. The U.S. Food and Drug Administration also sent a letter to health care providers warning of.
Covalent Modifiers
OCTOBER 21, 2023
Seong Ho Hong , Akane Osa , Ingrid E Wertz , Daniel Nomura bioRxiv 2023.10.20.563371; doi: [link] Targeted protein degradation with Proteolysis Targeting Chimeras (PROTACs) is a powerful therapeutic modality for eliminating disease-causing proteins through targeted ubiquitination and proteasome-mediated degradation. Most PROTACs have exploited substrate receptors of Cullin-RING E3 ubiquitin ligases such as cereblon and VHL.
Science Daily: Pharmacology News
OCTOBER 25, 2023
A new report finds that drastic changes are approaching if risks to our fundamental socioecological systems are not addressed. The Interconnected Disaster Risks Report 2023 warns of six risk tipping points ahead of us: Accelerating extinctions; Groundwater depletion; Mountain glaciers melting; Space debris; Unbearable heat; and an Uninsurable future.
BioPharma Drive: Drug Pricing
OCTOBER 27, 2023
In a wide-ranging interview, Bristol Myers’ Ken Rhodes talked biomarkers, diseases of interest and why the company is far from done with neuroscience-focused deals.
Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.
The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven
Drugs.com
OCTOBER 27, 2023
FRIDAY, Oct. 27, 2023 -- The U.S. Consumer Product Safety Commission and Dorel Juvenile Group have announced a recall of an infant/toddler activity center due to injuries. The Cosco Jump, Spin & Play Activity Centers were sold exclusively at.
Covalent Modifiers
OCTOBER 24, 2023
Justin T. Cruite, Radosław P. Nowak, Katherine A. Donovan, Scott B. Ficarro, Huang Huang, Hu Liu, Yingpeng Liu, Jarrod A. Marto, Rebecca J. Metivier, Eric S. Fischer, and Lyn H. Jones ACS Medicinal Chemistry Letters 2023 DOI: 10.1021/acsmedchemlett.3c00371 Site-specific modification of amino acid residues in protein binding pockets using sulfonyl exchange chemistry expands the druggable proteome by enabling the development of covalent modulators that target residues beyond cysteine.
Science Daily: Pharmacology News
OCTOBER 25, 2023
Smart glasses that use a technique similar to a bat's echolocation could help blind and low-vision people navigate their surroundings, according to researchers.
BioPharma Drive: Drug Pricing
OCTOBER 23, 2023
The clearance of the pentavalent shot Penbraya adds to Pfizer’s infectious disease portfolio as it adjusts to slumping COVID-19 vaccine sales.
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Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.
Drugs.com
OCTOBER 27, 2023
THURSDAY, Oct. 26, 2023 -- More than half of working-age Americans struggle to afford their health care and many forgo care, possibly risking their health, according to a new survey. The Commonwealth Fund survey queried more than 7,800 individuals.
Covalent Modifiers
OCTOBER 26, 2023
Giavana R. Prucha, Sean Henry, Klarissa Hollander, Zachary J. Carter, Krasimir A. Spasov, William L. Jorgensen, Karen S. Anderson, European Journal of Medicinal Chemistry , 2023, 262, 115894, [link] Reverse transcriptase (RT) is one of three key proteins responsible for the replication cycle of HIV-1 in the host. Several classes of inhibitors have been developed to target the enzyme, with non-nucleoside reverse transcriptase inhibitors forming first-line treatment.
Science Daily: Pharmacology News
OCTOBER 25, 2023
Researchers have now developed a technique that advances the ability of these tools, such as ChatGPT, to make compositional generalizations. This technique, Meta-learning for Compositionality, outperforms existing approaches and is on par with, and in some cases better than, human performance.
BioPharma Drive: Drug Pricing
OCTOBER 24, 2023
The startup is taking aim at an inflammation-linked protein known as TSLP, which is the target of an approved asthma medicine.
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Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.
Drugs.com
OCTOBER 25, 2023
WEDNESDAY, Oct. 25, 2023 -- Clinical trials investigating use of two widely available products -- vitamin C and the statin drug simvastatin -- in critically ill COVID patients have yielded far different results. Simvastatin had a 96% likelihood of.
Broad Institute
OCTOBER 23, 2023
New patient-partnered research project will study heart disease and diabetes risk in South Asian populations By Corie Lok October 23, 2023 Breadcrumb Home New patient-partnered research project will study heart disease and diabetes risk in South Asian populations The OurHealth study aims to increase representation of people of South Asian ancestry in cardiometabolic research.
Science Daily: Pharmacology News
OCTOBER 23, 2023
A team of researchers has created smart, advanced materials that will be the building blocks for a future generation of soft medical microrobots. These tiny robots have the potential to conduct medical procedures, such as biopsy, and cell and tissue transport, in a minimally invasive fashion.
BioPharma Drive: Drug Pricing
OCTOBER 26, 2023
Executives at the biotech say they’re trying to get ahead of the payer and production challenges that will face their gene editing treatment exa-cel, which is now under FDA review.
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Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic
Drugs.com
OCTOBER 25, 2023
WEDNESDAY, Oct. 25, 2023 -- Toos electric scooters are a fire hazard and people should stop using them, the U.S. Consumer Product Safety Commission (CPSC) warned Monday.
Collaborative Drug
OCTOBER 26, 2023
Collaborative Drug Discovery Sponsors the BrazMedChem-2023 Conference
Science Daily: Pharmacology News
OCTOBER 26, 2023
Smart, stretchable and highly sensitive, a new soft sensor opens the door to a wide range of applications in robotics and prosthetics. When applied to the surface of a prosthetic arm or a robotic limb, the sensor skin provides touch sensitivity and dexterity, enabling tasks that can be difficult for machines such as picking up a piece of soft fruit.
BioPharma Drive: Drug Pricing
OCTOBER 27, 2023
The restructuring came as the French company forecast an earnings drop in 2024, prompting a stock selloff that erased about $20 billion in market value.
Drugs.com
OCTOBER 24, 2023
MONDAY, Oct. 23, 2023 -- Not all high school injuries happen on the football field or the basketball court. Marching band is also a physically demanding activity and participants can suffer injuries, as seen in a new study that looked at emergency.
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