ASPET
DECEMBER 22, 2023
This study provides a unique translational research opportunity to help both humans and dogs diagnosed with diseases that carry dismal prognoses in both species: histiocytic sarcoma (HS), hemangiosarcoma (HSA), and disseminated mastocytosis/mast cell tumor (MCT). While exceedingly rare in humans, these so called "orphan diseases" are relatively more common in dogs.
Chemical Biology and Drug Design
DECEMBER 17, 2023
Prediabetes rat model was induced by high-fat diet and a normal diet was used as a control. They were fed for 20 weeks. At week 13, the model rats were given 100 mg/kg Berberine by gavage for 7 weeks. OGTT, fasting blood glucose, blood lipid, insulin level, and insulin resistance index were measured in each group. The cognitive function of rats was observed by a water maze test and new object recognition experiment.
BioPharma Drive: Drug Pricing
DECEMBER 20, 2023
The Healey center is at the front of ALS research and care, earning acclaim from patients, doctors and scientists. Still, the complexities of the disease and of drug development have brought hard-felt losses.
Science Daily: Pharmacology News
DECEMBER 18, 2023
An interdisciplinary team consisting of researchers has revealed a striking similarity between the memory processing of artificial intelligence (AI) models and the hippocampus of the human brain. This new finding provides a novel perspective on memory consolidation, which is a process that transforms short-term memories into long-term ones, in AI systems.
Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.
The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven
Nvidia Developer: Drug Discovery
DECEMBER 19, 2023
Enzymes are vital biological catalysts for a multitude of processes, from cellular metabolism to industrial manufacturing. The applications of artificial. Enzymes are vital biological catalysts for a multitude of processes, from cellular metabolism to industrial manufacturing. The applications of artificial intelligence for enzyme generation is an exciting field of research with direct applications in the life sciences.
Broad Institute
DECEMBER 18, 2023
Q&A: How to jump-start new psychiatric and neurological drug development By Tom Ulrich December 18, 2023 Breadcrumb Home Q&A: How to jump-start new psychiatric and neurological drug development Stanley Center director Steve Hyman talks about a new report he co-authored that explores the obstacles in developing new treatments and how to overcome them By Tom Ulrich December 18, 2023 Steven Hyman Related people Steven Hyman Related programs Stanley Center for Psychiatric Research Related News Scien
Drug Discovery Digest brings together the best content for drug research and development professionals from the widest variety of industry thought leaders.
Science Daily: Pharmacology News
DECEMBER 18, 2023
The Earth is a wonderful blue and green dot covered with oceans and life, while Venus is a yellowish sterile sphere that is not only inhospitable but also sterile. However, the difference between the two bears to only a few degrees in temperature. A team of astronomers has achieved a world's first by managing to simulate the entirety of the runaway greenhouse process which can transform the climate of a planet from idyllic and perfect for life, to a place more than harsh and hostile.
Antidote
DECEMBER 22, 2023
Because Antidote’s key focus is connecting patients to clinical trials , hearing directly from individuals serves as a great reminder of why we do what we do. One patient we’ve had the pleasure of speaking with is Linda VandeVrede, a former high-tech PR executive who shared her story of chronic pain, clinical trials, and personal experience.
Broad Institute
DECEMBER 20, 2023
With AI, researchers identify a new class of antibiotic candidates By Tom Ulrich December 20, 2023 Breadcrumb Home With AI, researchers identify a new class of antibiotic candidates New compounds can kill methicillin-resistant Staphylococcus aureus (MRSA), an often-lethal bacterial pathogen By Anne Trafton, MIT News Office December 20, 2023 Methicillin-resistant Staphylococcus aureus (gold) on the remains of an immune cell (red) Related people James Collins Related programs Infectious Disease an
Drugs.com
DECEMBER 22, 2023
FRIDAY, Dec. 22, 2023 -- A man becoming incredibly uncomfortable when a woman starts crying – to the point he’ll do anything to make her stop – is a reliable old chestnut in TV and movies.But there appears to be a biochemical truth to that.
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Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.
Science Daily: Pharmacology News
DECEMBER 20, 2023
The intricate process of duplicating genetic information, referred to as DNA replication, lies at the heart of the transmission of life from one cell to another and from one organism to the next. This happens by not just simply copying the genetic information; a well-orchestrated sequence of molecular events has to happen at the right time. Scientists have recently uncovered a fascinating aspect of this process known as 'replication timing' (RT) and how special this is when life commences.
Perficient: Drug Development
DECEMBER 18, 2023
In the fast-paced realm of finance, the significance of regulatory risk and compliance management practices cannot be overstated. This blog post delves into the pivotal role these practices play in ensuring the stability and success of financial institutions and banks. By adopting a proactive stance and leveraging technological advancements, financial entities can navigate the regulatory landscape with greater resilience and efficacy.
Drug Target Review
DECEMBER 22, 2023
In this eBook, Drug Target Review breaks down the potential of stem cells for personalised regenerative medicine, offering practical insights into their role in healthcare. Simultaneously, Ellen Capon reveals new biomarkers for diabetic kidney disease, reshaping diagnostics and treatment approaches.
Drugs.com
DECEMBER 21, 2023
THURSDAY, Dec. 21, 2023 -- It may seem a bit counterintuitive, but treating the pancreas of a child with autism could help ease problematic behaviors, new research shows.The key here, researchers say, is the link between dietary protein intake and.
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Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.
Science Daily: Pharmacology News
DECEMBER 19, 2023
Are we able to differentiate between the vocal emissions of certain primates? A team asked volunteers to categorize the vocalizations of three species of great apes (Hominidae) and humans. During each exposure to these ''onomatopoeia'', brain activity was measured. Unlike previous studies, the scientists reveal that phylogenetic proximity -- or kinship -- is not the only factor influencing our ability to identify these sounds.
Collaborative Drug
DECEMBER 19, 2023
The Research Informatics and Development groups at CDD are continually developing computational tools within CDD Vault to help accelerate drug discovery. The newest addition to this suite of features is a novel Deep Learning model to aid medicinal chemists.
Drug Target Review
DECEMBER 21, 2023
A recently published study 1 from a large team of cell biologists sheds new light on cellular organisation and variability. Researchers at the Allen Institute for Cell Science , a division of the Allen Institute in Seattle, US, developed a unique mathematical framework to uncover internal organisation of cellular structures in human induced pluripotent stem cells (hiPSCs) while taking account of the wide range of variation that naturally occurs in cell shapes.
Drugs.com
DECEMBER 22, 2023
FRIDAY, Dec. 22, 2023 -- People are being maimed by unauthorized fat-dissolving injections meant to tighten up double chins and dissipate flab along the arms, thighs and stomach, the U.S. Food and Drug Administration warns.The shots are supposed to.
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Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic
Science Daily: Pharmacology News
DECEMBER 19, 2023
Early in the 1970s, paleontologists discovered strange fossilized fruits between hardened rock from one of the largest volcanic eruptions in Earth's history. The identity of these fossils remained elusive for the next several decades. Using CT scanning, scientists have now determined they are the oldest fossils from species in the Frankincense and Myrrh family.
NIOSH Science Blog: Drugs
DECEMBER 22, 2023
Mined raw materials, or products produced from them, are essential for all industries. Mining will remain an essential industry even with the shift to sustainable energy as critical minerals that will support the needs for zero-emission vehicles, carbon-free energy, and production of energy resources and everyday products must be mined. Respirable crystalline silica (RCS) is one of the most prevalent and severe health hazards in mining – one that has been well-known since the Hawks Nest Tunnel D
Drug Target Review
DECEMBER 22, 2023
Can you tell us about your journey in the field of STEM and the challenges you encountered along the way? My journey and interest in STEM began initially because of my secondary school Biology and Chemistry teachers. Both were woman teachers who were passionate about science and very good teachers to boot. I attended an all-girls secondary school in Ireland which strongly encouraged us to study STEM in both secondary and third-level education.
Drugs.com
DECEMBER 22, 2023
FRIDAY, Dec. 22, 2023 -- Can’t afford Ozempic?You might soon have another weight-loss option, in the form of an ingestible vibrating capsule that tricks the body into thinking the stomach is full.Animals given the multivitamin-sized pill 20.
Science Daily: Pharmacology News
DECEMBER 21, 2023
A lot has changed in the world since the Endangered Species Act (ESA) was enacted 50 years ago in December 1973. Experts are now discuss how the ESA has evolved and what its future might hold.
Elrig
DECEMBER 19, 2023
Relive Drug Discovery 23 with SelectScience’s hub that features exclusive content from the event. The post ELRIG Drug Discovery 2023 meeting highlights first appeared on ELRIG.
Drug Target Review
DECEMBER 21, 2023
Where do you see the future of mRNA biology and AI converging, and how does Anima Biotech plan to lead this convergence? mRNA biology has become widely recognised as a new “drug mine” RNAi drugs are in the market and mRNA vaccines, initially developed for Covid-19, are already in trials for cancer. mRNA is an intermediate form that codes the instructions for making proteins but the biology around its regulation is not well understood and is still an “uncracked code” Compl
Drugs.com
DECEMBER 22, 2023
FRIDAY, Dec. 22, 2023 -- Over 15 million Americans have signed up for health insurance using the Affordable Care Act's federal marketplace, a 33% increase from the year before, preliminary government data shows.On Dec. 15, the deadline for coverage.
Science Daily: Pharmacology News
DECEMBER 22, 2023
Researchers have analyzed more than one million galaxies to explore primordial fluctuations that seeded the formation of the structure of the entire universe.
Elrig
DECEMBER 16, 2023
Hope Amos, Scientific Communication Specialist at Nanolive SA, unveils Nanolive's groundbreaking label-free, machine learning-powered assays, revolutionizing drug discovery. Discover how their holotomography technology offers high-resolution, 3D imaging of cellular components, shedding light on metabolic stress without cell death. The post Machine learning powered assays advance drug discovery first appeared on ELRIG.
Drug Target Review
DECEMBER 21, 2023
As we navigate the current landscape of pharmaceutical exploration, we discern a future in which healthcare is characterised by personalised medicines and precision-targeted treatments. To provide comprehensive insights into ongoing developments, we are pleased to present the latest edition of Drug Target Review. This issue encompasses a spectrum of topics, including proteomics, upstream bioprocessing, immuno-oncology, CRISPR and screening.
Drugs.com
DECEMBER 19, 2023
TUESDAY, Dec. 19, 2023 -- Probiotics might be able to help people dodge the worst effects of COVID-19, new clinical trial results show.Unvaccinated people who took a lactobacillus-laced probiotic had reduced COVID symptoms and even delayed.
Science Daily: Pharmacology News
DECEMBER 20, 2023
Conventional wisdom suggests that searching online to evaluate the veracity of misinformation would reduce belief in it. But a new study by a team of researchers shows the opposite occurs: Searching to evaluate the truthfulness of false news articles actually increases the probability of believing misinformation.
Elrig
DECEMBER 16, 2023
Join Stuart Farrow, VP of Biosciences at Cancer Research Horizons, as he reveals groundbreaking insights with SelectScience on AI, immuno-oncology, and personalized medicine's synergy in advancing effective cancer treatments. The post Why personalized medicine is the future of cancer treatment first appeared on ELRIG.
BioPharma Drive: Drug Pricing
DECEMBER 19, 2023
The biotechnology company’s share price fell more than 10% Tuesday after the disclosure of more data from a small study.
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