Forbes: Drug Truths

JANUARY 11, 2024

The FDA had been previously reluctant to approve such a plan for safety concerns.

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FDA Drugs 249

Drug Target Review

JANUARY 8, 2024

What is “healthspan” and how does it relate to Life Bioscience’s mission? It is no mystery that as we age our health starts to deteriorate, and we become increasingly susceptible to diseases. If we take into consideration the timeframe of our lives, our “healthspan” is defined as the number of healthy years we live, which is different than our lifespan, the number of years of life.

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Science Daily: Pharmacology News

JANUARY 11, 2024

Restricting calories is known to improve health and increase lifespan, but much of how it does so remains a mystery, especially in regard to how it protects the brain. Scientists have now uncovered a role for a gene called OXR1 that is necessary for the lifespan extension seen with dietary restriction and is essential for healthy brain aging.

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Drugs.com

JANUARY 12, 2024

FRIDAY, Jan. 12, 2024 -- A universal coronavirus vaccine could have saved millions of lives and billions of dollars if one had been available prior to the pandemic, a new study argues. Further, a universal vaccine -- one that targets parts of the.

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Vaccine 137

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Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

Clinical Trials

addgene Blog

JANUARY 11, 2024

Addgene is announcing we have chosen to stop all activity on X, formerly Twitter. If you are interested in engaging with us on social media, you can find us on Bluesky: @addgene.bsky.social; or @addgene on Instagram, TikTok, Facebook, and LinkedIn. We are also exploring other social media platforms with active scientific communities and welcome suggestions in the comments.

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Antidote

JANUARY 12, 2024

An estimated 1 in 10,000 people have primary sclerosing cholangitis (PSC) , a condition that impacts the bile ducts that run between the liver, the gallbladder, and the small intestine. The liver produces bile to transport to the gallbladder for storage, or to the small intestine where it aids in the digestion of fats. In the case of PSC, there is inflammation in the bile ducts (cholangitis) which leads to scarring (sclerosis) that narrows the ducts.

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Drugs.com

JANUARY 12, 2024

FRIDAY, Jan. 12, 2024 -- Sickle cell disease is one of many chronic health conditions that dramatically increases the risk of hospitalization and death in people infected by COVID-19.Unfortunately, folks with sickle cell disease are much less.

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BioPharma Drive: Drug Pricing

JANUARY 12, 2024

Arena BioWorks, which will be led by Harvard University scientist Stuart Schreiber, seeks to blend academic and venture capital drug research models.

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Drug Research Research Drugs 130

LifeSciVC

JANUARY 12, 2024

Biotech feels like it’s got some wind in its sails here at the start of 2024, with positive sentiments from the JPM conference. Indeed, the public equity markets feeling somewhat buoyant for the first time in ages. With the close out of 2023, it’s time to take stock of the health of the private venture ecosystem. Analyzing Pitchbook data for venture funding into US-based biopharma companies, at least four themes are worth highlighting related to overall funding, startup creation, mega-rounds, an

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Marketing Science 113

Science Daily: Pharmacology News

JANUARY 8, 2024

Researchers have developed a new lithium metal battery that can be charged and discharged at least 6,000 times -- more than any other pouch battery cell -- and can be recharged in a matter of minutes. The research not only describes a new way to make solid state batteries with a lithium metal anode but also offers new understanding into the materials used for these potentially revolutionary batteries.

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Research 126

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Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

Clinical Trials

Drugs.com

JANUARY 9, 2024

TUESDAY, Jan. 9, 2024 -- HIV pre-exposure prophylaxis (PrEP) is a lifeline for Americans, many of them gay men, who are at high risk of contracting the virus that causes AIDS.But a case that is winding its way through the court system might push.

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Virus 119

BioPharma Drive: Drug Pricing

JANUARY 9, 2024

Albert Bourla acknowledged Pfizer’s difficult 2023, while a biotech CEO spoke with BioPharma Dive about building neuroscience startups.

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Drug Target Review

JANUARY 12, 2024

How does the integration of Real-World Data (RWD) with genomic biomarker data contribute to a more comprehensive understanding of disease progression and treatment response? Most drugs do not work in all people. This one size fits all approach to drug prescribing still pervades in mostly all therapy areas except oncology. So, knowing an individual and something about their profile, whether that be biomarkers such as genomic data, blood-based markers or even transcriptomics of tissues or blood, p

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Perficient: Drug Development

JANUARY 9, 2024

Medical device industry trends for 2024. The medical device industry is in a constant state of evolution. We are seeing more sophisticated consumer expectations, advancements in technology, regulatory changes, and changing healthcare needs – just to name a few. As we gaze into our crystal ball, five key trends have bubbled up. Let’s look at what is poised to impact the medical device industry in 2024.

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Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

Clinical Trials

Drugs.com

JANUARY 11, 2024

THURSDAY, Jan. 11, 2024 -- U.S. doctors are prescribing antifungal creams to patients with skin complaints at rates so high they could be contributing to the rise of drug-resistant infections, new research shows.These are "severe.

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BioPharma Drive: Drug Pricing

JANUARY 8, 2024

The chip maker struck a new deal with Amgen on Monday, while Sarepta brought news of strong sales to the J.P. Morgan Healthcare Conference.

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Drug Target Review

JANUARY 8, 2024

In this eBook, we explore how researchers identified two unique proteins within N. fowleri – self-activating guanine nucleotide-hydrolysing proteins (G proteins) – that present novel targets for drug discovery. This article summarises their work to date, including a high-throughput fluorescence assay of guanine nucleotide hydrolysis for rapid But that’s not all.

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Science Daily: Pharmacology News

JANUARY 11, 2024

Scientists have developed a way to convert carbon dioxide (CO2), a potent greenhouse gas, into carbon nanofibers, materials with a wide range of unique properties and many potential long-term uses. Their strategy uses tandem electrochemical and thermochemical reactions run at relatively low temperatures and ambient pressure and could successfully lock carbon away to offset or even achieve negative carbon emissions.

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Drugs.com

JANUARY 12, 2024

FRIDAY, Jan. 12, 2024 -- The Quaker Oats Co has widened a recall of granola bars and cereals that was first announced in December, adding more products that may potentially be contaminated with salmonella.The products were sold in all U.S. states.

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Production 111

BioPharma Drive: Drug Pricing

JANUARY 10, 2024

Many drugmakers hope to compete in obesity, while others seek to win oncology’s next era. In the background, a contentious drug pricing law looms.

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Drugs 120

Antidote

JANUARY 10, 2024

One of the most important results of the work we do at Antidote is directly impacting the lives of patients — and getting to hear their stories is a constant reminder of why we do what we do.

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Research 105

Perficient: Drug Development

JANUARY 10, 2024

If you’ve worked with Optimizely CMS, you might be pretty familiar with TinyMCE. Its the amazing rich text editor that works seamlessly with Optimizely CMS. And some of you may have worked with some or other form of customization with it in projects, be it adding additional styles, work with different plugins, format the toolbar to suit your clients’ requirements and more.

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Drugs.com

JANUARY 11, 2024

THURSDAY, Jan. 11, 2024 -- Amid an ongoing shortage of the first-line treatment for syphilis in the United States, the U.S. Food and Drug Administration will allow the importation of a different syphilis drug from a French drugmaker. In a.

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BioPharma Drive: Drug Pricing

JANUARY 8, 2024

At the J.P. Morgan Healthcare Conference Monday, company head Chris Viehbacher said insurance reimbursement is now ‘not an issue’ for treatment.

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Drug Target Review

JANUARY 10, 2024

There is extensive crosstalk between the DNA damage response (DDR) and innate immune pathways. Both are a focus for exciting new small-molecule drug therapeutics that target cancers and autoimmune disorders. The Transcreener HTS Assay platform accelerates these efforts by providing robust and easy-to-use biochemical assays for key enzymes in the pathways.

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Science Daily: Pharmacology News

JANUARY 10, 2024

Combining a biological heart and a silicone robotic pump, researchers created a biorobotic heart that beats like a real one, with a focus on a valve on the left side of the heart. The heart valve simulator can mimic the structure, function, and motion of a healthy or diseased heart, allowing surgeons and researchers to demonstrate various interventions while collecting real-time data.

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Disease Research 122

Drugs.com

JANUARY 8, 2024

MONDAY, Jan. 8, 2024 -- Folks quenching their thirst with bottled water can expect to chug down hundreds of thousands of minute plastic particles with their refreshing H2O, a new study reports.On average, a liter of bottled water contains some.

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Drug Channels

JANUARY 12, 2024

Today’s guest post comes from Maria Kirsch, President, Patient Services, Krista Pinto, President, Deployment Solutions, and Mike Scott, Senior Vice President, Specialty Consulting at EVERSANA. Maria, Krista, and Mike discuss the key reasons why patients abandon drug therapy. They then describe EVERSANA’s approach for helping manufacturers and healthcare providers improve adherence and health outcomes.

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Therapies Drugs 98

On Medicine

JANUARY 8, 2024

Kidney cancer poses a significant healthcare burden in the UK, with 13,000 new patients diagnosed annually, a 52% survival rate, and nearly 5,000 patients dying each year. The US faces similar problems, with 81,000 new cases and nearly 14,000 deaths annually. The incidence of renal cell carcinoma (RCC) has more than doubled in the last 50 years and is increasing by 2-3% every year.

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Science Daily: Pharmacology News

JANUARY 8, 2024

A groundbreaking study has found that evolution is not as unpredictable as previously thought, which could allow scientists to explore which genes could be useful to tackle real-world issues such as antibiotic resistance, disease and climate change. The study challenges the long-standing belief about the unpredictability of evolution, and has found that the evolutionary trajectory of a genome may be influenced by its evolutionary history, rather than determined by numerous factors and historical

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Drugs.com

JANUARY 8, 2024

MONDAY, Jan. 8, 2024 -- Paxlovid might help shorten and diminish a COVID infection, but the antiviral doesn’t reduce the risk of developing long COVID, a new study shows.About 16% of COVID patients treated with Paxlovid wound up with long COVID.

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Drug Channels

JANUARY 9, 2024

For 2024, the three largest pharmacy benefit managers (PBMs)—Caremark (CVS Health), Express Scripts (Cigna), and OptumRx (United Health Group)—have again each excluded 600 or more drugs from their standard formularies. You can find our updated counting below. This year, Humira and its 13 biosimilars will provide the most intriguing formulary drama. Unfortunately, the gross-to-net bubble will remain a fixture for this category, despite a price war led by almost half of the biosimilars.

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BioPharma Drive: Drug Pricing

JANUARY 8, 2024

The acquisition will build out Merck’s pipeline of immunotherapies as its top-seller Keytruda nears the end of U.S. market exclusivity.

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Marketing 109

Science Daily: Pharmacology News

JANUARY 11, 2024

Record heat across the world profoundly impacted the global water cycle in 2023, contributing to severe storms, floods, megadroughts and bushfires, new research shows.

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Research 125