Drug Target Review
JANUARY 8, 2024
What is “healthspan” and how does it relate to Life Bioscience’s mission? It is no mystery that as we age our health starts to deteriorate, and we become increasingly susceptible to diseases. If we take into consideration the timeframe of our lives, our “healthspan” is defined as the number of healthy years we live, which is different than our lifespan, the number of years of life.
Broad Institute
JANUARY 8, 2024
Researchers engineer in vivo delivery system for prime editing, partially restoring vision in mice By Corie Lok January 8, 2024 Breadcrumb Home Researchers engineer in vivo delivery system for prime editing, partially restoring vision in mice By adapting virus-like particles to carry the machinery for a type of gene editing called prime editing, scientists have corrected disease-causing mutations in animals and increased editing efficiency.
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Science Daily: Pharmacology News
JANUARY 11, 2024
Restricting calories is known to improve health and increase lifespan, but much of how it does so remains a mystery, especially in regard to how it protects the brain. Scientists have now uncovered a role for a gene called OXR1 that is necessary for the lifespan extension seen with dietary restriction and is essential for healthy brain aging.
Practical Cheminformatics
JANUARY 8, 2024
Picking up where we left off in Part I , this post covers several other ML in drug discovery topics that interested me in 2023. Some areas, like large language models, are new, and most of the work is at the proof-of-concept stage. Others, like active learning, are more mature, and several groups are starting to explore nuances of the methods. Here’s the structure of Part II. 4.
Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.
The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven
Drugs.com
JANUARY 12, 2024
FRIDAY, Jan. 12, 2024 -- A universal coronavirus vaccine could have saved millions of lives and billions of dollars if one had been available prior to the pandemic, a new study argues. Further, a universal vaccine -- one that targets parts of the.
Drug Discovery Digest brings together the best content for drug research and development professionals from the widest variety of industry thought leaders.
Science Daily: Pharmacology News
JANUARY 8, 2024
In recent years, there has been rising concern that tiny particles known as microplastics are showing up basically everywhere on Earth, from polar ice to soil, drinking water and food. Formed when plastics break down into progressively smaller bits, these particles are being consumed by humans and other creatures, with unknown potential health and ecosystem effects.
addgene Blog
JANUARY 11, 2024
Addgene is announcing we have chosen to stop all activity on X, formerly Twitter. If you are interested in engaging with us on social media, you can find us on Bluesky: @addgene.bsky.social; or @addgene on Instagram, TikTok, Facebook, and LinkedIn. We are also exploring other social media platforms with active scientific communities and welcome suggestions in the comments.
Drugs.com
JANUARY 12, 2024
FRIDAY, Jan. 12, 2024 -- Sickle cell disease is one of many chronic health conditions that dramatically increases the risk of hospitalization and death in people infected by COVID-19.Unfortunately, folks with sickle cell disease are much less.
BioPharma Drive: Drug Pricing
JANUARY 9, 2024
Albert Bourla acknowledged Pfizer’s difficult 2023, while a biotech CEO spoke with BioPharma Dive about building neuroscience startups.
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Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.
Science Daily: Pharmacology News
JANUARY 11, 2024
Scientists have developed a way to convert carbon dioxide (CO2), a potent greenhouse gas, into carbon nanofibers, materials with a wide range of unique properties and many potential long-term uses. Their strategy uses tandem electrochemical and thermochemical reactions run at relatively low temperatures and ambient pressure and could successfully lock carbon away to offset or even achieve negative carbon emissions.
Antidote
JANUARY 12, 2024
An estimated 1 in 10,000 people have primary sclerosing cholangitis (PSC) , a condition that impacts the bile ducts that run between the liver, the gallbladder, and the small intestine. The liver produces bile to transport to the gallbladder for storage, or to the small intestine where it aids in the digestion of fats. In the case of PSC, there is inflammation in the bile ducts (cholangitis) which leads to scarring (sclerosis) that narrows the ducts.
Drugs.com
JANUARY 9, 2024
TUESDAY, Jan. 9, 2024 -- HIV pre-exposure prophylaxis (PrEP) is a lifeline for Americans, many of them gay men, who are at high risk of contracting the virus that causes AIDS.But a case that is winding its way through the court system might push.
BioPharma Drive: Drug Pricing
JANUARY 8, 2024
The chip maker struck a new deal with Amgen on Monday, while Sarepta brought news of strong sales to the J.P. Morgan Healthcare Conference.
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Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.
Science Daily: Pharmacology News
JANUARY 8, 2024
Researchers have developed a new lithium metal battery that can be charged and discharged at least 6,000 times -- more than any other pouch battery cell -- and can be recharged in a matter of minutes. The research not only describes a new way to make solid state batteries with a lithium metal anode but also offers new understanding into the materials used for these potentially revolutionary batteries.
Drug Target Review
JANUARY 12, 2024
How does the integration of Real-World Data (RWD) with genomic biomarker data contribute to a more comprehensive understanding of disease progression and treatment response? Most drugs do not work in all people. This one size fits all approach to drug prescribing still pervades in mostly all therapy areas except oncology. So, knowing an individual and something about their profile, whether that be biomarkers such as genomic data, blood-based markers or even transcriptomics of tissues or blood, p
Drugs.com
JANUARY 11, 2024
THURSDAY, Jan. 11, 2024 -- U.S. doctors are prescribing antifungal creams to patients with skin complaints at rates so high they could be contributing to the rise of drug-resistant infections, new research shows.These are "severe.
BioPharma Drive: Drug Pricing
JANUARY 10, 2024
Many drugmakers hope to compete in obesity, while others seek to win oncology’s next era. In the background, a contentious drug pricing law looms.
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Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic
Science Daily: Pharmacology News
JANUARY 11, 2024
Record heat across the world profoundly impacted the global water cycle in 2023, contributing to severe storms, floods, megadroughts and bushfires, new research shows.
Drug Patent Watch
JANUARY 8, 2024
The article “Settled: Patent characteristics and litigation outcomes in the pharmaceutical industry,” explores the relationship between Paragraph IV litigation characteristics and the probability of a Paragraph IV settlement in the… The post Unveiling the Secrets of Patent Litigation and Settlements in Pharmaceuticals appeared first on DrugPatentWatch - Make Better Decisions.
Drugs.com
JANUARY 12, 2024
FRIDAY, Jan. 12, 2024 -- The Quaker Oats Co has widened a recall of granola bars and cereals that was first announced in December, adding more products that may potentially be contaminated with salmonella.The products were sold in all U.S. states.
Drug Target Review
JANUARY 8, 2024
In this eBook, we explore how researchers identified two unique proteins within N. fowleri – self-activating guanine nucleotide-hydrolysing proteins (G proteins) – that present novel targets for drug discovery. This article summarises their work to date, including a high-throughput fluorescence assay of guanine nucleotide hydrolysis for rapid But that’s not all.
Science Daily: Pharmacology News
JANUARY 10, 2024
Combining a biological heart and a silicone robotic pump, researchers created a biorobotic heart that beats like a real one, with a focus on a valve on the left side of the heart. The heart valve simulator can mimic the structure, function, and motion of a healthy or diseased heart, allowing surgeons and researchers to demonstrate various interventions while collecting real-time data.
Drug Patent Watch
JANUARY 9, 2024
A recent story by NPR echoes the findings of a collaboration between DrugPatentWatch and Bloomberg, which examined increasing competition between generic drug makers. The NPR article discusses the challenges in… The post NPR on how low Drug Prices can Shortages appeared first on DrugPatentWatch - Make Better Decisions.
Drugs.com
JANUARY 11, 2024
THURSDAY, Jan. 11, 2024 -- Amid an ongoing shortage of the first-line treatment for syphilis in the United States, the U.S. Food and Drug Administration will allow the importation of a different syphilis drug from a French drugmaker. In a.
Perficient: Drug Development
JANUARY 9, 2024
Medical device industry trends for 2024. The medical device industry is in a constant state of evolution. We are seeing more sophisticated consumer expectations, advancements in technology, regulatory changes, and changing healthcare needs – just to name a few. As we gaze into our crystal ball, five key trends have bubbled up. Let’s look at what is poised to impact the medical device industry in 2024.
Science Daily: Pharmacology News
JANUARY 8, 2024
An international team of researchers has found that Africa's birds of prey are facing an extinction crisis. The report warns of declines among nearly 90% of 42 species examined, and suggests that more than two-thirds may qualify as globally threatened.
BioPharma Drive: Drug Pricing
JANUARY 8, 2024
At the J.P. Morgan Healthcare Conference Monday, company head Chris Viehbacher said insurance reimbursement is now ‘not an issue’ for treatment.
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