Science Daily: Pharmacology News
JANUARY 11, 2024
Restricting calories is known to improve health and increase lifespan, but much of how it does so remains a mystery, especially in regard to how it protects the brain. Scientists have now uncovered a role for a gene called OXR1 that is necessary for the lifespan extension seen with dietary restriction and is essential for healthy brain aging.
Drugs.com
JANUARY 12, 2024
FRIDAY, Jan. 12, 2024 -- Sickle cell disease is one of many chronic health conditions that dramatically increases the risk of hospitalization and death in people infected by COVID-19.Unfortunately, folks with sickle cell disease are much less.
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
BioPharma Drive: Drug Pricing
JANUARY 12, 2024
Arena BioWorks, which will be led by Harvard University scientist Stuart Schreiber, seeks to blend academic and venture capital drug research models.
Collaborative Drug
JANUARY 11, 2024
Celebrating 20 Years of Pioneering Drug Discovery and Collaboration: CDD User Group Meeting
Speaker: Simran Kaur, Co-founder & CEO at Tattva.Health
AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!
Science Daily: Pharmacology News
JANUARY 8, 2024
In recent years, there has been rising concern that tiny particles known as microplastics are showing up basically everywhere on Earth, from polar ice to soil, drinking water and food. Formed when plastics break down into progressively smaller bits, these particles are being consumed by humans and other creatures, with unknown potential health and ecosystem effects.
Drug Discovery Digest brings together the best content for drug research and development professionals from the widest variety of industry thought leaders.
BioPharma Drive: Drug Pricing
JANUARY 9, 2024
Albert Bourla acknowledged Pfizer’s difficult 2023, while a biotech CEO spoke with BioPharma Dive about building neuroscience startups.
Covalent Modifiers
JANUARY 11, 2024
Aaron B. Keeley, Aleksandra Kopranovic, Vincenzo Di Lorenzo, Péter Ábrányi-Balogh, Niklas Jänsch, Linh N. Lai, László Petri, Zoltán Orgován, Daniel Pölöske, Anna Orlova, András György Németh, Charlotte Desczyk, Tímea Imre, Dávid Bajusz, Richard Moriggl, Franz-Josef Meyer-Almes, and György M. Keserü Journal of Medicinal Chemistry 2024 67 (1), 572-585 [link] Screening of ultra-low-molecular weight ligands (MiniFrags) successfully identified viable chemical starting points for a variety of drug tar
Science Daily: Pharmacology News
JANUARY 11, 2024
Scientists have developed a way to convert carbon dioxide (CO2), a potent greenhouse gas, into carbon nanofibers, materials with a wide range of unique properties and many potential long-term uses. Their strategy uses tandem electrochemical and thermochemical reactions run at relatively low temperatures and ambient pressure and could successfully lock carbon away to offset or even achieve negative carbon emissions.
Drugs.com
JANUARY 9, 2024
TUESDAY, Jan. 9, 2024 -- HIV pre-exposure prophylaxis (PrEP) is a lifeline for Americans, many of them gay men, who are at high risk of contracting the virus that causes AIDS.But a case that is winding its way through the court system might push.
Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.
The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven
BioPharma Drive: Drug Pricing
JANUARY 8, 2024
The chip maker struck a new deal with Amgen on Monday, while Sarepta brought news of strong sales to the J.P. Morgan Healthcare Conference.
Covalent Modifiers
JANUARY 10, 2024
Dr. Luís A. R. Carvalho, Bárbara B. Sousa, Daniel Zaidman, Hannah Kiely-Collins, Prof. Gonçalo J. L. Bernardes Nat Commun 10 , 5811 (2019). [link] PROTAC linker design remains mostly an empirical task. We employed the PRosettaC computational software in the design of sulfonyl-fluoride-based PROTACs targeting acyl protein thioesterase 1 (APT1). The software efficiently generated ternary complex models from empirically-designed PROTACs and suggested alkyl linkers to be the preferred type of linker
Science Daily: Pharmacology News
JANUARY 8, 2024
Researchers have developed a new lithium metal battery that can be charged and discharged at least 6,000 times -- more than any other pouch battery cell -- and can be recharged in a matter of minutes. The research not only describes a new way to make solid state batteries with a lithium metal anode but also offers new understanding into the materials used for these potentially revolutionary batteries.
Drugs.com
JANUARY 11, 2024
THURSDAY, Jan. 11, 2024 -- U.S. doctors are prescribing antifungal creams to patients with skin complaints at rates so high they could be contributing to the rise of drug-resistant infections, new research shows.These are "severe.
Advertisement
Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.
BioPharma Drive: Drug Pricing
JANUARY 10, 2024
Many drugmakers hope to compete in obesity, while others seek to win oncology’s next era. In the background, a contentious drug pricing law looms.
Covalent Modifiers
JANUARY 11, 2024
Eric W. J. Gates, Adrien Prince-Hallée, Yasaman Heidari, Abootaleb Sedighi, and Jeffrey W. Keillor Biochemistry 2023 62 (21), 3085-3095 DOI: 10.1021/acs.biochem.3c00337 Transglutaminases (TGases) are a family of calcium-dependent enzymes primarily known for their ability to cross-link proteins. Transglutaminase 2 (TG2) is one isozyme in this family whose role is multifaceted.
Science Daily: Pharmacology News
JANUARY 11, 2024
Record heat across the world profoundly impacted the global water cycle in 2023, contributing to severe storms, floods, megadroughts and bushfires, new research shows.
Drugs.com
JANUARY 8, 2024
MONDAY, Jan. 8, 2024 -- Paxlovid might help shorten and diminish a COVID infection, but the antiviral doesn’t reduce the risk of developing long COVID, a new study shows.About 16% of COVID patients treated with Paxlovid wound up with long COVID.
Advertisement
Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.
BioPharma Drive: Drug Pricing
JANUARY 8, 2024
At the J.P. Morgan Healthcare Conference Monday, company head Chris Viehbacher said insurance reimbursement is now ‘not an issue’ for treatment.
Collaborative Drug
JANUARY 8, 2024
Resurrection Biology, leveraging AI in cancer drug response prediction, weight loss drugs boom isn't over, and how hibernation research can save your life.
Science Daily: Pharmacology News
JANUARY 10, 2024
Combining a biological heart and a silicone robotic pump, researchers created a biorobotic heart that beats like a real one, with a focus on a valve on the left side of the heart. The heart valve simulator can mimic the structure, function, and motion of a healthy or diseased heart, allowing surgeons and researchers to demonstrate various interventions while collecting real-time data.
Drugs.com
JANUARY 12, 2024
FRIDAY, Jan. 12, 2024 -- The Quaker Oats Co has widened a recall of granola bars and cereals that was first announced in December, adding more products that may potentially be contaminated with salmonella.The products were sold in all U.S. states.
Advertisement
Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic
BioPharma Drive: Drug Pricing
JANUARY 8, 2024
The acquisition will build out Merck’s pipeline of immunotherapies as its top-seller Keytruda nears the end of U.S. market exclusivity.
Covalent Modifiers
JANUARY 8, 2024
Min Liu, Chunjian Wu, Rui Wang, Jiaming Qiu, Zhentao She, Jianan Qu, and Jiang Xia ACS Central Science 2023 9 (12), 2358-2368 DOI: 10.1021/acscentsci.3c01068 Signaling proteins often form biomolecular condensates through liquid–liquid phase separation (LLPS) during intracellular signal transduction. Modulating the LLPS property of intracellular protein condensates will redirect intracellular signals and provide a potential way to regulate cellular physiology.
Science Daily: Pharmacology News
JANUARY 8, 2024
In the culmination of a decade's worth of effort, scientists analyzed an unprecedented sample of more than 1,500 supernovae classified using machine learning. They placed the strongest constraints on the expansion of the universe ever obtained with the DES supernova survey. While consistent with the current standard cosmological model, the results do not rule out a more complex theory that the density of dark energy in the universe could have varied over time.
Drugs.com
JANUARY 11, 2024
THURSDAY, Jan. 11, 2024 -- Amid an ongoing shortage of the first-line treatment for syphilis in the United States, the U.S. Food and Drug Administration will allow the importation of a different syphilis drug from a French drugmaker. In a.
BioPharma Drive: Drug Pricing
JANUARY 8, 2024
An unusual FTC challenge could have implications for startups, while industry watchers are waiting to see if the sector’s recent momentum signals an end to a lengthy funding crunch.
Expert insights. Personalized for you.
355 
Let's personalize your content