BioPharma Drive: Drug Pricing
MAY 16, 2024
The biotech, tentatively named Hercules CM Newco, has rights to three incretin drugs discovered by Jiangsu Hengrui Pharmaceuticals, two of which are in clinical testing.
Broad Institute
MAY 16, 2024
New gene delivery vehicle shows promise for human brain gene therapy By Allessandra DiCorato May 16, 2024 Breadcrumb Home New gene delivery vehicle shows promise for human brain gene therapy Scientists have engineered an adeno-associated virus (AAV) that efficiently crosses the blood-brain barrier in human cell models and delivers genes throughout the brain in humanized mice.
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Science Daily: Pharmacology News
MAY 15, 2024
It's one thing to dream up a quantum internet that could send hacker-proof information around the world via photons superimposed in different quantum states. It's quite another to physically show it's possible. That's exactly what physicists have done, using existing Boston-area telecommunication fiber, in a demonstration of the world's longest fiber distance between two quantum memory nodes to date.
Chemical Biology and Drug Design
MAY 17, 2024
The study screened and identified furochromenones that impact tyrosinase activity. One of the furochromenones ( 3k ) inhibited while another ( 4f ) stimulated tyrosinase. Abstract Tyrosinase is a copper-containing enzyme involved in the biosynthesis of melanin pigment. While the excess production of melanin causes hyperpigmentation of human skin, hypopigmentation results in medical conditions like vitiligo.
Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.
The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven
BioPharma Drive: Drug Pricing
MAY 13, 2024
Goldman Sachs and Eli Lilly are among those backing the startup, which claims its prospect could be more potent than the myelofibrosis therapies that have come to market in recent years.
Drugs.com
MAY 16, 2024
THURSDAY, May 16, 2024 -- Following a vegetarian or vegan diet might just buy you a longer, healthier life, a new review finds.Staying away from meat was tied to a reduced risk of heart disease, cancer and early death, researchers reported in a.
Drug Discovery Digest brings together the best content for drug research and development professionals from the widest variety of industry thought leaders.
Perficient: Drug Development
MAY 14, 2024
In the ever-evolving landscape of healthcare, trust reigns supreme. As consumers increasingly rely on data to inform their decisions, the healthcare industry faces a pressing need to not only meet but exceed expectations. With disruptive forces emerging from various corners, healthcare organizations find themselves in a race to create personalized experiences that foster lasting engagement and trust.
BioPharma Drive: Drug Pricing
MAY 16, 2024
While results indicated the drug works as intended, it didn’t have enough of an effect on a protein that’s become integral to many ALS research programs.
Drugs.com
MAY 15, 2024
WEDNESDAY, May 15, 2024 -- The U.S. Food and Drug Administration has approved a kit that will allow women to collect their own vaginal sample for HPV screening, a move that could increase early detection in those at risk for cervical cancer. Women.
Science Daily: Pharmacology News
MAY 13, 2024
Today's rate of atmospheric carbon dioxide increase is 10 times faster than at any other point in the past 50,000 years, researchers have found through a detailed chemical analysis of ancient Antarctic ice.
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Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.
FDA Law Blog: Biosimilars
MAY 13, 2024
By Jeffrey N. Gibbs & Ana Loloei & Véronique Li, Senior Medical Device Regulation Expert — FDA has long touted the use of real-world evidence ( RWE ). Extolling RWE, FDA has said “RWE can be leveraged to bring new products to market, evaluate the safety and effectiveness of existing products for new uses, and assess the continued performance and safety of products once on the market.
BioPharma Drive: Drug Pricing
MAY 16, 2024
The results, which showed Lilly’s drug was as effective at controlling blood sugar as standard injections, come as Novo Nordisk seeks approval for a competing once-weekly insulin.
Drugs.com
MAY 17, 2024
FRIDAY, May 17, 2024 -- Mice, rats and other wildlife can pick up bacteria called leptospira from water or soil and excrete it in urine. If your dog contacts any soil or water contaminated by the germ (especially if they have an open wound) they.
Science Daily: Pharmacology News
MAY 15, 2024
The ability to regulate body temperature, a trait all mammals and birds have today, may have evolved among some dinosaurs early in the Jurassic period about 180 million years ago. The new study looked at the spread of dinosaurs across different climates on Earth throughout the Mesozoic Era (the dinosaur era lasting from 230 to 66 million years ago), drawing on 1,000 fossils, climate models and the geography of the period, and dinosaurs' evolutionary trees.
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Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.
Perficient: Drug Development
MAY 14, 2024
We’re excited to announce our Data Cloud Expert specialization! This is the highest level of Salesforce-validated expertise for Data Cloud. This achievement isn’t just a milestone, it’s a testament to our commitment to revolutionizing how businesses leverage their data to drive business outcomes, unlock trapped data, and enhance customer experiences.
BioPharma Drive: Drug Pricing
MAY 15, 2024
The annual forecast, which comes as Eisai and Biogen have begun submitting a more convenient form of Leqembi for approval, looks “more realistic” than previous guidance, according to Jefferies analysts.
Drugs.com
MAY 15, 2024
WEDNESDAY, May 15, 2024 -- An experimental gene therapy could one day provide a first-ever cure for genital and oral herpes, researchers report.The gene therapy removed 90% or more of oral herpes infection in lab mice, and it also suppressed how.
Science Daily: Pharmacology News
MAY 14, 2024
The vast majority of people have an ongoing conversation with themselves, an inner voice, that plays an important role in their daily lives. But between 5-10 per cent of the population do not have the same experience of an inner voice, and they find it more difficult to perform certain verbal memory tasks, new research shows.
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Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic
PLOS: DNA Science
MAY 16, 2024
COVID took the world by stunned surprise – but, to quote an old Who song, we won’t be fooled again. That’s thanks to accelerated genome sequencing technologies, expanded laboratory capabilities, and interacting infrastructure on a global level. These factors are converging to enable both identification of novel infectious diseases as well as microbial resistance, before these threats can impact public health, write a team from the European Society for Clinical Microbiology and
BioPharma Drive: Drug Pricing
MAY 16, 2024
Full study results disclosed ahead of a medical meeting showed elinzanetant consistently reduced the frequency and severity of hot flashes.
Drugs.com
MAY 14, 2024
TUESDAY, May 14, 2024 -- Babies born by C-section are unlikely to receive protection from a single dose of measles vaccine, a new study finds.A single measles jab is up to 2.
Science Daily: Pharmacology News
MAY 13, 2024
An experimental treatment made from a plant virus is effective at protecting against a broad range of metastatic cancers in mice, shows a new study. The treatment, composed of nanoparticles fashioned from the cowpea mosaic virus -- a virus that infects black-eyed pea plants -- showed remarkable success in improving survival rates and suppressing the growth of metastatic tumors across various cancer models, including colon, ovarian, melanoma and breast cancer.
addgene Blog
MAY 14, 2024
Modular cloning is a popular DNA assembly tool used to build single- and multi-gene constructs for a variety of applications. MoClo tools can be used in bacterial and cell-free expression systems, mammalian cells, yeast, flies, and even plants! In this blog we will review common uses of MoClo and the kits Addgene offers to kickstart these applications, no matter what your model organism is.
Broad Institute
MAY 14, 2024
Merkin Prize in Biomedical Technology awarded to F. William Studier for development of widely used protein- and RNA-production platform By Corie Lok May 14, 2024 Breadcrumb Home Merkin Prize in Biomedical Technology awarded to F. William Studier for development of widely used protein- and RNA-production platform The $400,000 award recognizes the far-reaching medical impacts of Studier’s development, in the 1980s, of an efficient and scalable technology to produce mass amounts of RNA and proteins
Drugs.com
MAY 13, 2024
MONDAY, May 13, 2024 -- People with heart failure are often prescribed what are known as loop diuretic medications to help reduce the fluid buildup that's a hallmark of the disease.Now, research suggests that taking the blockbuster weight loss drug.
Science Daily: Pharmacology News
MAY 17, 2024
The latest findings forecast that global life expectancy will increase by 4.9 years in males and 4.2 years in females between 2022 and 2050. Increases are expected to be largest in countries where life expectancy is lower, contributing to a convergence of increased life expectancy across geographies. The trend is largely driven by public health measures that have prevented and improved survival rates from cardiovascular diseases, COVID-19, and a range of communicable, maternal, neonatal, and nut
addgene Blog
MAY 16, 2024
In flow cytometry, compensation is the process of correcting spillover from one fluorescent channel to another. When you label your samples with multiple antibodies, the fluorescent probes on the antibodies may have similar emission spectra, meaning they will emit fluorescent light at similar wavelengths (See this handy emission spectra chart to find your antibody's spectra ).
Drug Channels
MAY 14, 2024
Contrary to what you may have heard, the Inflation Reduction Act’s (IRA) inflation rebates for Medicare Part B drugs do not always save money for seniors. As we document below, a growing share of Part B drugs have inflation-adjusted coinsurance rates that have been increasing , not declining. In many cases, the coinsurance rate declines only briefly before rebounding back to the standard 20% rate.
Drugs.com
MAY 17, 2024
FRIDAY, May 17, 2024 -- The U.S. Justice Department on Thursday moved to reclassify marijuana as a less dangerous drug, setting the stage for a significant shift in the nation's drug policy.In a proposed rule sent to the federal register, officials.
Science Daily: Pharmacology News
MAY 14, 2024
Researchers have found that 2023 was the hottest summer in the Northern Hemisphere in the past two thousand years, almost four degrees warmer than the coldest summer during the same period.
DrugBank
MAY 15, 2024
The road to developing effective drugs is fraught with both promise and challenge, particularly when it comes to what scientists call "undruggable" targets. Let's break down what this means and why it matters to us all. The Evolution of Drug Discovery: From Dark Rooms to Precision Targets In the past, drug discovery often felt like a lucky guess.
Conversations in Drug Development Trends
MAY 14, 2024
By: Amy Raymond, Derek Ansel, Nathan Chadwick, & Juliane Mills When choosing a CRO for a rare disease study, what truly sets them apart is their methodology: the CRO’s mindset, their approach to each unique study, and their agility in navigating the inherent complexities of rare disease research. The team’s ability to apply insights and proven strategies from their experience in rare disease research brings concepts to reality, getting medications to patients faster.
Drugs.com
MAY 15, 2024
WEDNESDAY, May 15, 2024 -- In a small pilot study, some young women looking to lose weight on a low-calorie keto diet got an unexpected benefit: Their acne began to clear up.“These findings represent an opportunity to control a skin disease that.
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