Practical Cheminformatics
JANUARY 16, 2024
Following up on Part I and Part II, the third post in this series is a collection of review articles published in 2023 that I found helpful.
LifeSciVC
JANUARY 16, 2024
By Aimee Raleigh, Principal at Atlas Venture, as part of the From The Trenches feature of LifeSciVC Just in time for new years’ reflections and resolutions, this year’s JPM felt like a refreshing burst of enthusiasm for a sector that has seen its challenges in 2022 and 2023 but also some green shoots. 2023 was a stellar year for M&A, comeback stories, burgeoning “hot” spaces, and for re-learning the basics of belt-tightening and careful capital allocation.
Broad Institute
JANUARY 18, 2024
Injectable agents could improve liquid biopsy for cancer detection and monitoring By Corie Lok January 18, 2024 Breadcrumb Home Injectable agents could improve liquid biopsy for cancer detection and monitoring Researchers at Broad and MIT report the first injectable “priming agents” for liquid biopsy that increased circulating tumor DNA by more than 10-fold in mice.
Drugs.com
JANUARY 18, 2024
THURSDAY, Jan. 18, 2024 -- Expecting moms who often turn to acetaminophen for their aches and pains are more likely to wind up with kids who have behavioral issues, a new study warns.Children between the ages of 2 and 4 were more likely to have.
Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.
The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven
Science Daily: Pharmacology News
JANUARY 18, 2024
Researchers have designed a self-powering, battery-free, energy-harvesting sensor. Using the framework they developed, they produced a temperature sensor that can harvest and store the energy from the magnetic field that exists in the open air around a wire.
BioPharma Drive: Drug Pricing
JANUARY 17, 2024
The offering is the fifth outlined by a biotech startup this month, suggesting companies are becoming more willing to gauge investors’ appetite for new stock offerings.
Drug Discovery Digest brings together the best content for drug research and development professionals from the widest variety of industry thought leaders.
Perficient: Drug Development
JANUARY 19, 2024
Many retailers are embarking on a digital transformation to modernize and scale their order management system (OMS) solution. Built on a modern architecture, the solution wraps Docker containers around order management business services. This architecture streamlines application management and the release of new functionality. The container technology also supports varying levels of technical acumen, business continuity, security, and compliance.
Science Daily: Pharmacology News
JANUARY 14, 2024
New research for the first time reveals the function of a little-understood junction between cells in the brain that could have important treatment implications for conditions ranging from multiple sclerosis to Alzheimer's disease, to a type of brain cancer known as glioma. Neuroscientists focused on the synapse connecting neurons to a non-neuronal cell, known as oligodendrocyte precursor cells.
BioPharma Drive: Drug Pricing
JANUARY 19, 2024
Phase 3 trial results showed Lutathera cut the risk of disease progression or death by 72% as initial treatment for gastroenteropancreatic neuroendocrine tumors, or GEP-NETs.
Drugs.com
JANUARY 18, 2024
THURSDAY, Jan. 18, 2024 -- A daily multivitamin could help people keep their brains healthy as they age, a new trial finds.Results suggest taking multivitamins could help prevent memory loss and slow cognitive aging among older adults, researchers.
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Perficient: Drug Development
JANUARY 19, 2024
In the world of Generative Artificial Intelligence (AI), a new era of large language models has emerged with the remarkable capabilities. ChatGPT , Gemini , Bard and Copilot have made an impact in the way we interact with mobile device and web technologies. We will perform a comparative analysis to highlight the capabilities of each tool. ChatGPT Gemini Bard Copilot Training Data Web Web Web Web Accuracy 85% 85% 70% 80% Recall 85% 95% 75% 82% Precision 89% 90% 75% 90% F1 Score 91% 92% 75% 84% Mu
Science Daily: Pharmacology News
JANUARY 14, 2024
Earth's average surface temperature in 2023 was the warmest on record, according to an analysis by NASA. Global temperatures last year were around 2.1 degrees Fahrenheit (1.2 degrees Celsius) above the average for NASA's baseline period (1951-1980), scientists from NASA's Goddard Institute for Space Studies (GISS) in New York reported.
BioPharma Drive: Drug Pricing
JANUARY 17, 2024
The startup is focusing on immune cells called Tr1 cells, which it claims could be important in treating autoimmune conditions like graft-versus-host disease.
FDA Law Blog: Biosimilars
JANUARY 15, 2024
By David B. Clissold & Sara W. Koblitz — You know a court decision is going to be worth reading when the judges compare FDA’s regulatory governance of flavored e-cigarettes to a Shakespearean gaslighting. To quote the Fifth Circuit: “It was the regulatory equivalent of Romeo sending Mercutio on a wild goose chase—and then admitting there never was a goose while denying he even suggested the chase.
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Drug Target Review
JANUARY 15, 2024
Researchers from the Nara Institute of Science and Technology (NAIST) have used the reverse-blastocyst complementation (rBC) method to understand the conditions required to form lungs in rat-mouse chimeric models. They also used the tetraploid-based organ complementation (TOC) method to create a rat-derived lung in their mouse model. Chronic obstructive pulmonary disease Chronic obstructive pulmonary disease (COPD) is the third leading cause of global deaths.
Science Daily: Pharmacology News
JANUARY 18, 2024
The study reveals dramatic regional kelp canopy changes along the California coast over a 100-year period. During this time there was a significant increase in kelp forest canopy along the central coast, the only region of California where southern sea otters survived after being hunted nearly to extinction for their fur in the 1800s. Contrastingly, kelp canopy decreased in northern and southern regions.
BioPharma Drive: Drug Pricing
JANUARY 16, 2024
The agency’s decision to expand use of Casgey, which won a landmark OK for sickle cell disease in December, comes more than two months ahead of schedule.
Drugs.com
JANUARY 16, 2024
TUESDAY, Jan. 16, 2024 -- Magnetic zaps to the brain can significantly help people with severe depression, if the procedure is guided using MRI brain scans, a new clinical trial has concluded.On average, patients showed substantial improvements in.
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Drug Target Review
JANUARY 15, 2024
Monoclonal antibodies (mAbs) targeting tumour-specific antigens play an essential role in the treatment of many cancers. In general, these agents work by binding to a molecular target on the surface of a tumour cell, and directing destruction of the target cell by chemical, radiological or immunological mechanisms. This approach has produced a broad range of approved and investigational products.
Science Daily: Pharmacology News
JANUARY 18, 2024
Researchers have developed a light-based means of printing nano-sized metal structures that is 480 times faster and 35 times cheaper than the current conventional method. It is a scalable solution that could transform a scientific field long reliant on technologies that are prohibitively expensive and slow. Their method is called superluminescent light projection (SLP).
Antidote
JANUARY 18, 2024
Antidote’s mission is to connect patients with medical research so medical breakthroughs can take place. A key part of our strategy is partnering with nonprofits and patient advocacy groups. We provide our clinical trial matching technology, Antidote Match, at no cost to these organizations, to help patients and caregivers discover new research opportunities and connect to clinical trials quickly and easily.
Drugs.com
JANUARY 15, 2024
MONDAY, Jan. 15, 2024 -- Taking nitrates for heart problems alongside erectile dysfunction drugs like Viagra or Cialis could be a prescription for trouble, a new study warns.Men who combine the two types of medications have a higher risk of death.
Drug Target Review
JANUARY 19, 2024
Can you tell us about your journey in the field of STEM and the challenges you encountered along the way? My journey in the field of science has been highly enriching and gratifying. However, when I started my career in the pharma field, it was a male-dominated industry with minimal opportunities for women to grow and advance as leaders. I started working as a trainee immediately after submitting my PhD thesis in Analytical chemistry to Pune university in India but initially felt immense pressur
Science Daily: Pharmacology News
JANUARY 16, 2024
Fossils of kelp along the Pacific Coast are rare. Until now, the oldest fossil dated from 14 million years ago, leading to the view that today's denizens of the kelp forest -- marine mammals, urchins, sea birds -- coevolved with kelp. A recent amateur discovery pushes back the origin of kelp to 32 million years ago, long before these creatures appeared.
BioPharma Drive: Drug Pricing
JANUARY 18, 2024
The company said it has secured agreement from labor representatives in Germany for job cuts that will shed “many managerial employees.
Drugs.com
JANUARY 15, 2024
MONDAY, Jan. 15, 2024 -- Scientists from the U.S. Food and Drug Administration conclude in newly released documents that marijuana has less potential for abuse than other drugs with the same restrictions and it should be reclassified as a less.
Drug Target Review
JANUARY 15, 2024
Cancer is a disease driven by variable genetic mutations. Overcoming this variability while sparing normal cells has stymied broad-acting therapeutic development. Our innate immune system evolved to clear genetically diverse pathogens and limit host toxicity, raising the possibility that it can produce similar effects in cancer. Research 1 has shown that neutrophil elastase selectively and potently kills cancer cells irrespective of their genetics and anatomical origin, mobilises adaptive immuni
Science Daily: Pharmacology News
JANUARY 16, 2024
A study exploring the mechanisms behind why cognitive performance improves in response to exercise, has found that dopamine plays a key role.
KIF1A
JANUARY 13, 2024
#ScienceSaturday posts share exciting scientific developments and educational resources with the KAND community. Each week, Dr. Dylan Verden of KIF1A.ORG summarizes newly published KIF1A-related research and highlights progress in rare disease research and therapeutic development. KIF1A-Related Research A two-kinesin mechanism controls neurogenesis in the developing brain As we bring in the New Year with this week’s #ScienceSaturday we’re excited to share research from long-time Research Network
Drugs.com
JANUARY 19, 2024
FRIDAY, Jan. 19, 2024 -- People coming off antidepressants often struggle with emotional and social turmoil, especially if they quit their meds cold turkey, a new study reports.Challenges reported by patients quitting antidepressants included.
Perficient: Drug Development
JANUARY 17, 2024
Optimizely CMS comes with a package called Episerver.Forms that enables you to incorporate easy to build forms within a CMS website. There is a built in form container that supports standard built in form elements like input fields, checkboxes, radio buttons, select lists, buttons etc. And just like any other feature, Episerver Forms also come with the capability to customize, where you can customize existing elements, or create new ones and more.
Science Daily: Pharmacology News
JANUARY 19, 2024
Scientists have created a working nanoscale electomotor. The science team designed a turbine engineered from DNA that is powered by hydrodynamic flow inside a nanopore, a nanometer-sized hole in a membrane of solid-state silicon nitride. The tiny motor could help spark research into future applications such as building molecular factories or even medical probes of molecules inside the bloodstream.
BioPharma Drive: Drug Pricing
JANUARY 18, 2024
Called Advanced Medicine Partners, the new company will offer specialized cell and gene therapy manufacturing services to biotech and pharma clients.
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