Science Daily: Pharmacology News
MARCH 20, 2024
A study of over 20,000 adults found that those who followed an 8-hour time-restricted eating schedule, a type of intermittent fasting, had a 91% higher risk of death from cardiovascular disease.
Broad Institute
MARCH 22, 2024
Messenger RNAs with multiple “tails” could lead to more effective therapeutics By Corie Lok March 22, 2024 Breadcrumb Home Messenger RNAs with multiple “tails” could lead to more effective therapeutics Scientists have engineered long lasting mRNAs that increased therapeutic protein production in cells and animals. By Kat J. McAlpine March 22, 2024 Credit: Catherine Boush, Broad Communications Related news New method tracks gene expression in single cells over space and time Messenger RNA (mRNA)
Drugs.com
MARCH 18, 2024
MONDAY, March 18, 2024 -- As millions of Americans prepare to travel abroad this summer and measles outbreaks increase worldwide, the U.S. Centers for Disease Control and Prevention has tightened its guidance on how travelers should handle the.
BioPharma Drive: Drug Pricing
MARCH 22, 2024
The approval of Italfarmaco’s Duvyzat is the first for an oral, non-steroidal Duchenne drug and was issued for all patients at least six years of age, regardless of their genetic underpinnings.
Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.
The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven
Science Daily: Pharmacology News
MARCH 18, 2024
Performing a new task based solely on verbal or written instructions, and then describing it to others so that they can reproduce it, is a cornerstone of human communication that still resists artificial intelligence (AI). A team has succeeded in modelling an artificial neural network capable of this cognitive prowess. After learning and performing a series of basic tasks, this AI was able to provide a linguistic description of them to a 'sister' AI, which in turn performed them.
Broad Institute
MARCH 19, 2024
Researchers roll out a more accurate way to estimate genetic risks of disease By Claire Hendershot March 19, 2024 Breadcrumb Home Researchers roll out a more accurate way to estimate genetic risks of disease Two new approaches for generating polygenic scores demonstrate that compiled data improves score accuracy. By Claire Hendershot March 19, 2024 Image by Ricardo Job-Reese, Broad Communications.
Drug Discovery Digest brings together the best content for drug research and development professionals from the widest variety of industry thought leaders.
BioPharma Drive: Drug Pricing
MARCH 20, 2024
The company claims its approach could yield more effective and safer T-cell engagers, a type of cancer medicine that’s attracted significant interest from drugmakers in recent years.
Science Daily: Pharmacology News
MARCH 22, 2024
How much time do planets have to form from a swirling disk of gas and dust around a star? A new study gives scientists a better idea of how our own solar system came to be.
Broad Institute
MARCH 20, 2024
Spatial study of lung cancer reveals immune markers of response to immunotherapy By Corie Lok March 20, 2024 Breadcrumb Home Spatial study of lung cancer reveals immune markers of response to immunotherapy Researchers visualize how immune cells are spatially organized within tumors and show that certain immune “hubs” are linked to better treatment responses.
Drugs.com
MARCH 19, 2024
TUESDAY, March 19, 2024 -- Two of America's leading health organizations are highlighting a global rise in measles cases as yet another reason for families to make sure they get the measles vaccine.The U.S. Centers for Disease Control and.
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Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.
Perficient: Drug Development
MARCH 19, 2024
If you have built or are building a Data Lake on the Google Cloud Platform (GCP) and BigQuery you already know that BigQuery is a fully managed enterprise data warehouse that helps you manage and analyze your data with built-in features like machine learning, geospatial analysis, and business intelligence. BigQuery’s serverless architecture lets you use SQL queries to answer your organization’s biggest questions with zero infrastructure management.
Science Daily: Pharmacology News
MARCH 18, 2024
Venting about a source of anger might feel good in the moment, but it's not effective at reducing the rage, new research suggests. Instead, techniques often used to address stress -- deep breathing, mindfulness, meditation, yoga or even counting to 10 -- have been shown to be more effective at decreasing anger and aggression.
BioPharma Drive: Drug Pricing
MARCH 21, 2024
The job cuts at the cancer drug developer will primarily impact manufacturing roles, but will touch on several other parts of the organization, the company said.
Drugs.com
MARCH 20, 2024
WEDNESDAY, March 20, 2024 -- For the first time, the United States has fallen out of the top 20 spots on the annual world's happiest nations list.Americans are now No. 23, far behind the top five countries -- Finland (No.
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Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.
Perficient: Drug Development
MARCH 21, 2024
If you were to pop open any social media platform or news app right now and scroll through a couple dozen posts, you’ll easily get the feeling that everything is #%&$ falling apart. Everyone is mad at something. We now use the term “doomscrolling.” In the past we had Yellow Journalism and we are there once again. As humans we tend to get addicted to outrage and drama.
Science Daily: Pharmacology News
MARCH 20, 2024
A new study has shown that food-seeking cells exist in a part of a mouse's brain usually associated with panic -- but not with feeding. Activating a selective cluster of these cells kicked mice into 'hot pursuit' of live and non-prey food, and showed a craving for fatty foods intense enough that the mice endured foot shocks to get them, something full mice normally would not do.
Drug Target Review
MARCH 19, 2024
Could you describe the potential link between vitamin A levels and altered neuronal connectivity in psychiatric disorders? Vitamin A (retinol and all trans-retinoic acid) is important for brain development because it triggers the differentiation of neural progenitor cells into mature neurons with a complex dendritic arborisation (tree) with many connections with other neurons that collectively form the neural network that organises behaviour.
Drugs.com
MARCH 21, 2024
THURSDAY, March 21, 2024 -- People with heart disease can stay healthier if they address their emotional problems as well as their physical ailments, a new study says.Treating anxiety and depression reduced ER visits and hospitalizations among.
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Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic
Perficient: Drug Development
MARCH 20, 2024
In our latest podcast episode, Jim talks with Kristine Swan , the VP of Digital Transformation and IT at Bayer Crop Science , for a conversation that’s as rich and fertile as the soil our future depends on. Kristine brings a personal touch to the digital revolution in agriculture, drawing on her roots on a Missouri farm. With her at the helm, Bayer is not just sowing seeds but also sowing data – data that empowers farmers across the globe to tackle pressing challenges like climate change and sus
Science Daily: Pharmacology News
MARCH 22, 2024
It's no surprise that your dog can learn to sit when you say 'sit' and come when called. But a new study has made the unexpected discovery that dogs generally also know that certain words 'stand for' certain objects. When dogs hear those words, brain activity recordings suggest they activate a matching mental representation in their minds.
KIF1A
MARCH 16, 2024
#ScienceSaturday posts share exciting scientific developments and educational resources with the KAND community. Each week, Dr. Dylan Verden of KIF1A.ORG summarizes newly published KIF1A-related research and highlights progress in rare disease research and therapeutic development. KIF1A-Related Research Whole genome sequencing increases the diagnostic rate in Charcot-Marie-Tooth disease Charcot-Marie-Tooth (CMT) disease is an inherited disorder that causes degeneration of motor and sensory neuro
Drugs.com
MARCH 22, 2024
FRIDAY, March 22, 2024 -- If you're in your 60s, 70s or even older, you might think your days of productively pumping iron are behind you.That's just not true, said Dr. Adil Ahmed, an assistant professor in the Joseph Barnhart Department of.
Perficient: Drug Development
MARCH 22, 2024
Cloud modernization is the primary driver of digital transformation and impactful business value. Cloud platforms have evolved from core technology to disruptive ecosystems of strategic advantage. Migration and modernization are vital to reach new markets, deliver innovative products, improve resiliency, reduce costs, and improve customer experiences.
Science Daily: Pharmacology News
MARCH 18, 2024
Our eating habits in industrialized societies are far removed from those of ancient humans. This is impacting our intestinal flora, it seems, as newly discovered cellulose degrading bacteria are being lost from the human gut microbiome, especially in industrial societies.
sptlabtech
MARCH 20, 2024
In today’s scientific landscape, labs are under immense pressure to reduce costs, shorten timelines, and maximize output, often from limited resources. Lab automation has emerged as an incredibly valuable tool to address these challenges, empowering researchers to streamline processes and accelerate discoveries. By optimizing common laboratory tasks and processes, lab automation continues to demonstrate its value to the life science community.
Drugs.com
MARCH 22, 2024
FRIDAY, March 22, 2024 -- Working stiffs in the United States are dying at higher rates than those in other wealthy nations, a new study finds.Death rates among working-age Americans are 2.5 times higher than the average of other high-income.
Perficient: Drug Development
MARCH 19, 2024
Many times, in my career when performing QA, I’ve dealt with many times where I’ve felt uncertain about my efforts. Through my work at Perficient—and with the help of my team—I’ve learned over time how to persist and show grit in testing to be able to ensure the highest quality of work delivered throughout a project. Here are some tips to help your breakthrough any blockers you may have when performing QA.
Science Daily: Pharmacology News
MARCH 18, 2024
Leafhoppers, a common backyard insect, secrete and coat themselves in tiny mysterious particles that could provide both the inspiration and the instructions for next-generation technology, according to a new study. In a first, the team precisely replicated the complex geometry of these particles, called brochosomes, and elucidated a better understanding of how they absorb both visible and ultraviolet light.
PLOS: DNA Science
MARCH 21, 2024
The Food and Drug Administration just announced approval of Lenmeldy (atidarsagene autotemcel), a gene therapy to treat the neurological condition metachromatic leukodystrophy (MLD). Available in Italy for three years, Lenmeldy (atidarsagene autotemcel), from Orchard Therapeutics, is groundbreaking, but comes at quite a cost – the $4.25 million price tag for the one-time infusion, and for the older siblings who contributed to developing the gene treatment, but were too sick to receive it.
Drugs.com
MARCH 21, 2024
THURSDAY, March 21, 2024 -- As the pandemic wound down, life expectancy in the United States began to bounce back in 2022, although deaths among children increased and drug overdose deaths continued to reach record highs, new government research.
On Medicine
MARCH 20, 2024
In a recent blog post , I introduced our study developing a smart-sensing sock to detect and prevent diabetic foot ulcers caused by rubbing, and the importance of understanding patient context when designing health devices. We have now spoken with a range of people with diabetic neuropathy, as well as their carers and podiatrists, and asked them if, when, and how, they would use a device like the smart-sensing sock we are designing.
Science Daily: Pharmacology News
MARCH 22, 2024
Imagine if every time you saw a face, it appeared distorted. Well, for those who have a very rare condition known as prosopometamorphopsia (PMO), which causes facial features to appear distorted, that is reality. A new study reports on a unique case of a patient with PMO. The research is the first to provide accurate and photorealistic visualizations of the facial distortions experienced by an individual with PMO.
Covalent Modifiers
MARCH 22, 2024
Linqi Cheng Yixian Wang, Yiming Guo, Sophie S. Zhang Han Xiao C ell Chemical Biology, 2024 Volume 31, 3, 428 - 445 [link] j. chembiol. 2023.09.004 Recent years have seen a remarkable growth in the field of protein-based medical treatments. Nevertheless, concerns have arisen regarding the cytotoxicity limitations, low affinity, potential immunogenicity, low stability, and challenges to modify these proteins.
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