Drug Discovery Today
JANUARY 2, 2024
Researchers from the Royal Veterinary College (RVC) and University of Oxford have led an innovative project investigating the progression of malaria infection and the role of the parasite to better aid the development of an effective malaria vaccine and significantly reduce rates of deaths from the disease.
Science Daily: Pharmacology News
JANUARY 2, 2024
Human culture has evolved to allow humans to extract resources and helped us expand to dominate the biosphere. But the same evolutionary processes may counteract efforts to solve new global environmental threats like climate change, according to a new study. Tackling the climate crisis will require worldwide regulatory, technical and economic systems supported by strong global cooperation.
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BioPharma Drive: Drug Pricing
JANUARY 2, 2024
A non-addictive pain pill faces its definitive test, while study results in ALS, a rare heart disease and lung cancer could have far-reaching implications.
Drugs.com
JANUARY 4, 2024
THURSDAY, Jan. 4, 2024 -- The U.S. Food and Drug Administration is investigating reports of additional dangers linked to several wildly popular weight-loss drugs.In a quarterly report issued this week, the agency said it is investigating.
Speaker: Simran Kaur, Co-founder & CEO at Tattva.Health
AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!
Covalent Modifiers
JANUARY 3, 2024
Mathilde Goullieux, Vincent Zoete, and Ute F. Röhrig Journal of Chemical Information and Modeling 2023 63 (24), 7847-7859 DOI: 10.1021/acs.jcim.3c01055 Due to their various advantages, interest in the development of covalent drugs has been renewed in the past few years. It is therefore important to accurately describe and predict their interactions with biological targets by computer-aided drug design tools such as docking algorithms.
Drug Discovery Digest brings together the best content for drug research and development professionals from the widest variety of industry thought leaders.
BioPharma Drive: Drug Pricing
JANUARY 4, 2024
Moonwalk Biosciences, the latest biotech cofounded by the gene editing scientist, joins other startups aiming to alter gene expression without changing DNA.
Drugs.com
JANUARY 2, 2024
TUESDAY, Jan. 2, 2024 -- Managing diabetes will be a less expensive proposition for more Americans in 2024.Sanofi has officially joined Novo Nordisk and Eli Lilly in lowering the cost of insulin to $35 a month for many patients. The three.
Chemical Biology and Drug Design
JANUARY 4, 2024
Curcumin activates ATF6-regulated endoplasmic reticulum (ER) stress, promotes ATF6 nuclear translocation, activates Chop/Bax/Bcl-2/Caspase-3 apoptosis pathway, and promotes apoptosis of CRC cells. Abstract Colorectal cancer (CRC) is the main cause of cancer-associated death. Herein, we treated SW620 and HT-29 CRC cells with different curcumin concentrations, followed by treatment with the half maximal inhibitory concentration (IC50) curcumin/endoplasmic reticulum stress (ERS) inhibitor 4-phenyl
Science Daily: Pharmacology News
JANUARY 2, 2024
The African Matabele ants are often injured in fights with termites. Their conspecifics recognize when the wounds become infected and initiate antibiotic treatment.
Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.
The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven
BioPharma Drive: Drug Pricing
JANUARY 4, 2024
The company plans to restructure and will start a new late-stage study testing whether its “off-the-shelf” therapy can boost cure rates when used early on.
Drugs.com
JANUARY 5, 2024
FRIDAY, Jan. 5, 2024 -- The U.S. Food and Drug Administration on Friday gave the nod to a Florida plan to import drugs from Canada at much lower prices than in the United States.The approval could prove to be a major turning point for the United.
Collaborative Drug
JANUARY 5, 2024
Learn about tracking strategies, inventory management, and user-friendly features for labs handling biological and chemical data.
Science Daily: Pharmacology News
JANUARY 3, 2024
Fossils of a new group of animal predators have been located in the Early Cambrian Sirius Passet fossil locality in North Greenland. These large worms may be some of the earliest carnivorous animals to have colonized the water column more than 518 million years ago, revealing a past dynasty of predators that scientists didn't know existed.
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Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.
BioPharma Drive: Drug Pricing
JANUARY 5, 2024
The clearance is a major shift for the agency, which described its decision as a “first step” in allowing Florida to bulk purchase lower-cost Canadian medicines.
Drugs.com
JANUARY 5, 2024
FRIDAY, Jan. 5, 2024 -- Folks who take Ozempic or Wegovy for diabetes and weight loss need not worry about a higher risk of suicidal thoughts or feelings while on the medications, a new, large review finds.In the study, which was funded by the U.S.
Drug Target Review
JANUARY 2, 2024
In research published in Scientific Reports , 1 investigators focused on mesenchymal stem cells (MSCs), known for their potential in treating cell defects and regulating immune responses. Through a series of experiments, they successfully developed a personalised stem cell therapy using a data-driven, single-cell technique based on swift subcellular proteomic imaging.
Science Daily: Pharmacology News
JANUARY 4, 2024
A new study scientifically corroborates an event described in the Second Book of Kings -- the conquest of the Philistine city of Gath by Hazael King of Aram. The method is based on measuring the magnetic field recorded in burnt bricks. The researchers say that the findings are important for determining the intensity of the fire and the scope of destruction in Gath, and also for understanding construction practices in the region.
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Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.
BioPharma Drive: Drug Pricing
JANUARY 4, 2024
The agency could soon clear important new drugs from Eli Lilly and Merck, as well as the first treatment for a common liver disease.
Drugs.com
JANUARY 4, 2024
THURSDAY, Jan. 4, 2024 -- Researchers report that a new type of antibiotic has proved its mettle against a deadly superbug.Acinetobacter baumannii, a bacteria goes by the nickname CRAB, can trigger serious infections in the lungs, urinary tract and.
Antidote
JANUARY 5, 2024
Though clinical trial patient recruitment is an integral part of the medical research process, it is often one of the most difficult aspects of conducting a study. There are various reasons for this challenge, and among them is the widespread existence of misconceptions about participating in research that many patients may see as a barrier to entry.
Science Daily: Pharmacology News
JANUARY 2, 2024
A new analysis of fossils believed to be juveniles of T. rex now shows they were adults of a small tyrannosaur, with narrower jaws, longer legs, and bigger arms than T. rex. The species, Nanotyrannus lancensis, was first named decades ago but later reinterpreted as a young T. rex. The new study shows Nanotyrannus was a smaller, longer-armed relative of T. rex, with a narrower snout.
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Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic
BioPharma Drive: Drug Pricing
JANUARY 2, 2024
Amgen had its bid for full approval of the cancer drug Lumakras turned back by the agency, which also issued complete response letters to Zealand Pharma and Merck & Co. in December.
Drugs.com
JANUARY 3, 2024
WEDNESDAY, Jan. 3, 2024 -- A diet laden with omega-3 fatty acids found in nuts and oily fish might help slow the progression of pulmonary fibrosis, researchers report.Pulmonary fibrosis is a relentless, potentially fatal disease where lung tissue.
Antidote
JANUARY 2, 2024
The latest episode of Antidote’s quarterly podcast series Talk of the Towne is available now! Talk of the Towne is focused on bridging the gap between clinical discussion and patient centricity, hosted by Antidote’s Senior Clinical Informatics Manager, Dr. Richard Towne, PharmD.
Science Daily: Pharmacology News
JANUARY 5, 2024
Animal ecologists developed an analytical approach to better understand one of the latest threats to feathered creatures: the rise of wind and solar energy facilities.
BioPharma Drive: Drug Pricing
JANUARY 5, 2024
Lykos Therapeutics, formerly known as MAPS Public Benefit Corp., recently submitted its MDMA capsules for FDA approval, following two positive studies.
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