Drug Discovery World

SEPTEMBER 6, 2023

Phesi, a global provider of patient-centric data software and services, has partnered with Krystelis, a provider of medical writing and clinical trial transparency services, to launch its new Diversity, Equity, and Inclusion (DEI) Data Service. A 2022 Phesi data analysis discovered 42% of US cancer trial cohorts do not include African American patients, and almost half – 48% – have no Hispanic American patients.

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Broad Institute

SEPTEMBER 6, 2023

New research alliance with Novo Nordisk to identify therapeutic targets for type 2 diabetes and cardiometabolic diseases By Allessandra DiCorato September 6, 2023 Breadcrumb Home New research alliance with Novo Nordisk to identify therapeutic targets for type 2 diabetes and cardiometabolic diseases The collaboration aims to identify disease-modifying interventions, with the goal of improving standards of care for people living with type 2 diabetes and cardiac fibrosis By Broad Communications Sep

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BioPharma Drive: Drug Pricing

SEPTEMBER 6, 2023

Jane Grogan, an industry veteran who worked at Genentech for over 15 years, will take over the role starting Oct. 2. She’ll fill a seat that's lacked a permanent replacement since the departure of Al Sandrock.

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Drugs.com

SEPTEMBER 8, 2023

FRIDAY, Sept. 8, 2023 -- Receiving an organ transplant can be a nerve-wracking, if lifesaving, affair, said Dr. Joaquin Brieva, a kidney transplant recipient. “Within two days of my transplant, my kidney function was back to normal, but then.

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Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

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Drug Discovery World

SEPTEMBER 7, 2023

Researchers have discovered a new avenue of cell death in Alzheimer’s disease and vascular dementia. A new study, led by scientists at Oregon Health & Science University (OHSU), has revealed that a form of cell death known as ferroptosis – caused by a build-up of iron in cells – destroys microglia cells, a type of cell involved in the brain’s immune response, in cases of Alzheimer’s and vascular dementia.

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Drug Patent Watch

SEPTEMBER 5, 2023

Pharmacists play a crucial role in drug repurposing due to the vast amount of opportunities that exist in this innovative approach. Drug development and registration can be costly, time-consuming, and… The post Pharmacists Can Play Key Role in Drug Repurposing appeared first on DrugPatentWatch - Make Better Decisions.

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Drugs.com

SEPTEMBER 8, 2023

FRIDAY, Sept. 8, 2023 -- It's well known that certain forms of birth control carry a small risk of blood clots. Now a large new study suggests that some common painkillers can magnify that risk. The study, of 2 million Danish women, found what.

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Drug Discovery World

SEPTEMBER 7, 2023

DDW’s Diana Spencer highlights five key clinical studies taking a new therapeutic approach to childhood cancers. Over 100 subtypes of childhood cancer exist today and it represents the most common cause of disease-related death in children. However, despite the fact that children’s response to adult cancer drugs is often poor, due to the challenges of developing medicines for this population, only six drugs are made specifically for childhood cancer. 1 There are a number of challenges face

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Drug Target Review

SEPTEMBER 4, 2023

There have been several studies that have reported the ability of infectious disease agents to be drug resistant. Infectious agents’ resistance was described at the European Union Research Parliament “as a widespread, multifaceted phenomenon that affects both living things and the environment, as well as their capacity to survive in the presence of drugs intended to either kill or inactivate them.

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BioPharma Drive: Drug Pricing

SEPTEMBER 5, 2023

The FDA-approved therapy, called Palforzia, was little used, leading Nestle to abandon a business it had secured in a $2.6 billion deal three years ago.

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Drugs.com

SEPTEMBER 7, 2023

THURSDAY, Sept. 7, 2023 -- The blockbuster drug Ozempic has become a household name for its ability to spur weight loss. Now an early study hints at an intriguing possibility: The drug might allow people newly diagnosed with type 1 diabetes to drop.

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Drug Discovery World

SEPTEMBER 7, 2023

Following lengthy negotiations, the UK government has announced that the UK will be participating as a fully associated member of Horizon Europe for the remaining life of the programme to 2027. UK researchers can now apply for grants and bid to take part in projects under the Horizon programme. They will also be able to lead consortia in the next work programme of Horizon Europe projects.

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KIF1A

SEPTEMBER 2, 2023

#ScienceSaturday posts share exciting scientific developments and educational resources with the KAND community. Each week, Dr. Dylan Verden of KIF1A.ORG summarizes newly published KIF1A-related research and highlights progress in rare disease research and therapeutic development. 2023 KAND Family & Scientific Engagement Conference Wrap-up A happy Labor Day weekend to our readers in the US!

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BioPharma Drive: Drug Pricing

SEPTEMBER 8, 2023

Worth up to $840 million, the collaboration will give Alexion access to Verge Genomics’ platform, which uses human tissue data to find drug targets for diseases that degrade the nerve system.

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Drugs.com

SEPTEMBER 8, 2023

FRIDAY, Sept. 8, 2023 -- Therapies based on a hormone people make while exercising may be the next frontier in treating Alzheimer’s disease, according to a new study. Researchers have found that the exercise-induced hormone irisin may reduce both.

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Drug Discovery World

SEPTEMBER 5, 2023

It’s not unusual for such a dynamic industry to have regular shake-ups in senior leadership, especially as innovative new technologies create brand new roles. The last couple of months have seen a number of high-profile job moves in drug discovery. Dr Robert Kirby, COO and Dr Edward Stevens, CSO Metrion Biosciences Kirby has been promoted from his role as Director of Operations, where he oversaw Metrion’s recent site move and doubling of staff headcount.

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biobide

SEPTEMBER 8, 2023

Preclinical assays are a vital step in a drug’s journey to approval for use in human subjects. They allow drugs that are too toxic or unsafe to be filtered out in the Early Drug Discovery Phase prior to being tested on humans during the clinical phase. Also, Toxicology studies of the thousands of new chemical compounds there are being developed and the deeper study of others that are currently in use is of major relevance to ensure their safety.

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BioPharma Drive: Drug Pricing

SEPTEMBER 8, 2023

The PASTEUR Act could be heading for another legislative blow, but advocates say they see a future for the mechanism to fund research into antimicrobial resistance.

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Drugs.com

SEPTEMBER 8, 2023

FRIDAY, Sept. 8, 2023 -- New Swedish research suggests that up to 5% of 70-year-olds have glaucoma, and half of those diagnosed didn't even know they had the disease. “Of those who were diagnosed with glaucoma via the study, 15 people -- or 2.7%.

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Drug Discovery World

SEPTEMBER 5, 2023

BenevolentAI has dosed the first patients in Phase I first-in-human studies of its oral phosphodiesterase 10 (PDE10) inhibitor, BEN-8744, intended for the treatment of ulcerative colitis (UC). The topline data readout from this study is expected in the first quarter of 2024. UC is a chronic disease that causes inflammation and ulceration of the inner lining of the colon and rectum.

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Perficient: Drug Development

SEPTEMBER 7, 2023

Sitecore has form elements OOB that meet practically all form requirements. But in some scenarios, we may need to create a custom element to fulfill the requirement like the Cascading Dropdown List. We had a scenario where we needed to load all Products of selected Categories in dropdown lists. We intended to utilize the Sitecore SXA Filter. However, after selecting Category from the list, it loads the associated Products in the Products dropdown list while removing the other Category item from

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BioPharma Drive: Drug Pricing

SEPTEMBER 7, 2023

Fresh off a Series C fundraise, Kriya has acquired the privately held Tramotane Therapeutics and its preclinical candidate for the widely prevalent liver disease.

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Drugs.com

SEPTEMBER 7, 2023

THURSDAY, Sept. 7, 2023 -- Some people mistrust the safety and effectiveness of human vaccines for COVID-19 and other diseases, a fact that became abundantly clear during the pandemic. Now, a new survey of 2,200 dog owners shows this mistrust may.

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Drug Discovery World

SEPTEMBER 4, 2023

Kadans’ London Innovation Centre at Canary Wharf, London has launched its wet lab innovation and flexible workspace centre and welcomed a new tenant. AviadoBio, a gene therapy company developing medicines for neurodegenerative disorders, will establish laboratory and office presence at the Innovation Centre. The Innovation Centre has enabled the rapid growth of the life sciences hub at Canary Wharf , providing opportunities for early-stage life science companies to collaborate and innovate.

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ProRelix Research

SEPTEMBER 7, 2023

Autoimmune disorders comprise several diseases in which the immune system mistakenly attacks and destroys the body’s own healthy cells instead of destroying bacteria and viruses to keep the body healthy. […] The post Autoimmune disorders and current developments of novel treatments under clinical trials appeared first on ProRelix Research.

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BioPharma Drive: Drug Pricing

SEPTEMBER 5, 2023

The announcement marks progress for Beam after trial delays, and is the first time in the U.S. that a patient has received a base editing treatment.

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Drugs.com

SEPTEMBER 7, 2023

THURSDAY, Sept. 7, 2023 -- Emergency room visits for injuries related to driving under the influence of cannabis skyrocketed in Canada after the drug was legalized there, a new study reports. In October 2018, Canada became the second country to.

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Drug Discovery World

SEPTEMBER 4, 2023

In the third and final part of this series of articles focused on plant-based medicines, DDW’s Megan Thomas evaluates therapeutic breakthroughs using plant-based products in drug discovery. The first part of the series explored medical cannabis , and the second looked into psylocibin. Green tea Epigallocatechin gallate (EGCG), also known as epigallocatechin-3-gallate, is a type of catechin that is found in green tea.

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NIOSH Science Blog: Drugs

SEPTEMBER 6, 2023

We’re back for another Respiratory Protection Week! This year we’re shining some light on our Respirator Approval Program’s efforts to fill in gaps related to respiratory protection and answering some of your remaining questions about NIOSH Approved® respirators. As you may know, the National Institute for Occupational Safety and Health (NIOSH) is the federal institute responsible for the evaluation and approval of respirators used in U.S. occupational settings.

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BioPharma Drive: Drug Pricing

SEPTEMBER 5, 2023

The signals of a return to growth are emerging. As commercial leaders gear up for 2024 planning, they must prepare to fight for resources in a budget constrained environment.

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Drugs.com

SEPTEMBER 7, 2023

THURSDAY, Sept. 7, 2023 -- Respiratory syncytial virus (RSV) is a common viral infection that affects people of all ages, with infants and older adults being particularly vulnerable to severe complications. Preventing the spread of RSV requires a.

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Drug Discovery World

SEPTEMBER 8, 2023

News round-up for 4-8 September by DDW Digital Content Editor Diana Spencer. This week we have seen the vital importance of collaboration to the successful development and discovery of novel therapeutics, exemplified by the new deal agreed by the UK and EU to admit the UK back into Horizon Europe, the largest collaborative research programme in the world.

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keypoint

SEPTEMBER 6, 2023

Established in 2009, Keystone Symposia’s Fellows Program has become a premier professional advancement opportunity for rising scientists from diverse backgrounds. This unique one-year fellowship provides early-stage investigators (ESIs) (within 6 years of starting an independent research program) from underrepresented (UR) and other disadvantaged backgrounds with the support, skills and networking opportunities they need to successfully pursue research careers and leadership roles in academic, i

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Science Daily: Pharmacology News

SEPTEMBER 8, 2023

Researchers who created a soft robot that could navigate simple mazes without human or computer direction have now built on that work, creating a 'brainless' soft robot that can navigate more complex and dynamic environments.

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