Sat.Feb 24, 2024 - Fri.Mar 01, 2024

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Optimizing OpenFold Training for Drug Discovery

Nvidia Developer: Drug Discovery

Predicting 3D protein structures from amino acid sequences has been an important long-standing question in bioinformatics. In recent years, deep. Predicting 3D protein structures from amino acid sequences has been an important long-standing question in bioinformatics. In recent years, deep learning–based computational methods have been emerging and have shown promising results.

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AI outperforms humans in standardized tests of creative potential

Science Daily: Pharmacology News

In a recent study, 151 human participants were pitted against ChatGPT-4 in three tests designed to measure divergent thinking, which is considered to be an indicator of creative thought.

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Viking data suggest obesity drug could rival Zepbound, Wegovy

BioPharma Drive: Drug Pricing

The biotech’s drug led to significant weight loss in a Phase 2 trial, causing shares to double as analysts compared results to the marks set by drugs from Eli Lilly and Novo Nordisk.

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Eye Ointments Sold at Walmart, CVS Recalled Due to Infection Risk

Drugs.com

TUESDAY, Feb. 27, 2024 -- Eye ointment products made in India and sold in the United States at Walmart, CVS and other retailers are being recalled due to a danger of infection.Brassica Pharma Pvt. Ltd., of Maharastra, India, said it is recalling.

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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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Global survey of gut microbes uncovers 18 new bacterial species and clues to antibiotic resistance

Broad Institute

Global survey of gut microbes uncovers 18 new bacterial species and clues to antibiotic resistance By Leah Eisenstadt February 29, 2024 Breadcrumb Home Global survey of gut microbes uncovers 18 new bacterial species and clues to antibiotic resistance Researchers examined scat from hundreds of animals around the world and pinpointed genes that could fuel drug-resistant infections.

Hospitals 116
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Drug limits dangerous reactions to allergy-triggering foods, Stanford Medicine-led study of kids finds

Science Daily: Pharmacology News

A drug that binds to allergy-causing antibodies can protect children from dangerous reactions to accidentally eating allergy-triggering foods, a new study found.

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More Trending

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Treating Crohn's Sooner, More Aggressively Greatly Improves Outcomes: Study

Drugs.com

MONDAY, Feb. 26, 2024 -- In a finding that suggests sooner is better than later, a new trial shows that giving advanced treatment early to Crohn’s patients can dramatically improve their gut health.About 80% of those who got therapy with an.

Therapies 116
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CDC panel mulls changes to RSV vaccine recommendation

BioPharma Drive: Drug Pricing

The expert committee is discussing whether, for certain older adults, to make a universal recommendation for vaccination, rather than the current policy of “shared decisionmaking.

Vaccine 112
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Significant glacial retreat in West Antarctica began in 1940s

Science Daily: Pharmacology News

Among the vast expanse of Antarctica lies the Thwaites Glacier, the world's widest glacier measuring about 80 miles on the western edge of the continent. Despite its size, the massive landform is losing about 50 billion tons of ice more than it is receiving in snowfall, which places it in a precarious position in respect to its stability. Accelerating ice loss has been observed since the 1970s, but it is unclear when this significant melting initiated -- until now.

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Do You Have An Enterprise Data Strategy?

Perficient: Drug Development

This time of year, I like to talk about updating the data strategy for the new year to include new business goals and new technology and in doing so I sometimes forget that there are still many companies that do not have a data strategy to update. What is a Data Strategy and why do I need one? Most organizations have multiple data management initiatives underway including master data management, data governance, data migration, data modernization, OLTP operational data cleanup, data ingestion, a

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How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

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CDC Experts Recommend Seniors Get Another COVID Shot

Drugs.com

THURSDAY, Feb. 29, 2024 -- Even if they got a COVID booster last fall, American seniors should still get a second shot this spring to best protect themselves, U.S. health officials recommended Wednesday.The latest guidance, voted on by a vaccine.

Vaccine 111
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Rare Disease Day: Understanding the power of diagnosis and connection

Antidote

Rare Disease Day, typically observed on February 28th, will be celebrated this year on February 29th! Rare Disease Day is an awareness holiday intended to generate change for the 300 million people who are diagnosed with a rare disease worldwide, as well as their families and caregivers.

Disease 111
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New study links placental oxygen levels to fetal brain development

Science Daily: Pharmacology News

A new study shows oxygenation levels in the placenta, formed during the last three months of fetal development, are an important predictor of cortical growth (development of the outermost layer of the brain or cerebral cortex) and is likely a predictor of childhood cognition and behavior.

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Women in Stem with Dr Amber D. Van Laar

Drug Target Review

Can you tell us about your journey in the field of STEM and the challenges you encountered along the way? From a very young age, I was drawn to science and medicine. My interest in the field of STEM sharpened when, in my early teens, I had the chance to work in a neuro-oncology lab. This early exposure to bench science had a long-lasting impact. It propelled me to continue lab work during my undergraduate training, my medical training, and to an academic appointment in the Movement Disorders Div

Therapies 111
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Deliver Fast, Flexible Clinical Trial Insights with Spotfire

Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

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Say Goodbye to PFAS Chemicals in Food Packaging: FDA

Drugs.com

WEDNESDAY, Feb. 28, 2024 -- PFAS "forever" chemicals, increasingly linked to health risks, will no longer be added to food packaging handled by American consumers, the U.S. Food and Drug Administration announced Wednesday."Grease-proofing materials.

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#ScienceSaturday: February 24, 2024

KIF1A

#ScienceSaturday posts share exciting scientific developments and educational resources with the KAND community. Each week, Dr. Dylan Verden of KIF1A.ORG summarizes newly published KIF1A-related research and highlights progress in rare disease research and therapeutic development. KIF1A-Related Research A Model for Chemomechanical Coupling of Kinesin‑3 Motor Like humans, KIF1A pairs walk one step at a time, one foot in front of the other.

Disease 111
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Ultraviolet radiation from massive stars shapes planetary systems

Science Daily: Pharmacology News

Up to a certain point, very luminous stars can have a positive effect on the formation of planets, but from that point on the radiation they emit can cause the material in protoplanetary discs to disperse.

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A smartphone app for the self-management of Perthes’ Disease – a blog for Rare Disease Day 2024

On Medicine

What is Perthes’ disease? Perthes’ Disease is a rare condition that affects the developing femoral head (the “ball” of the “ball and socket” hip joint) of a child due to poor blood supply. In this condition, the blood supply to the femoral head is disrupted and this leads to joint deformity. The destruction typically causes the femoral head to flatten and not fit well in the acetabulum (the “socket” of the hip joint).

Disease 109
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Clinical Data Like You´ve Never Seen It Before: Why Spotfire Is the Leading Tool for Clinical Analytics

Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

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What Is Measles, and How Can I Shield Myself & My Family?

Drugs.com

WEDNESDAY, Feb. 28, 2024 -- Once thought to be a bygone disease, measles is making a comeback in the United States and globally as folks shun a safe, surefire way to prevent it: The measles vaccine. But what is measles, and how easily does it.

Vaccine 111
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Morgan Stanley Supercharged Its Customer Journey. Learn How at Adobe Summit 2024!

Perficient: Drug Development

Adobe Summit 2024 is right around the corner, and we’re excited to sit down with the executive director of marketing applications at Morgan Stanley Dorothy Joseph on March 27 at 11:30 A.M PST at The Grand Lux Café in The Palazzo. Perficient’s Jay Jackson, director of Adobe Digital Marketing and CDP, will host a fireside chat with Joseph about the global financial services leader’s successful journey to consolidate and optimize the Adobe Experience Platform.

Marketing 109
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Obesity drug from Boehringer, Zealand succeeds in MASH trial

BioPharma Drive: Drug Pricing

Zealand shares rose by more than one-third on the data, which provide further evidence so-called incretin drugs could help treat people with the liver disease.

Trials 114
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The future of cancer immunotherapy with Elicio Therapeutics

Drug Target Review

Can you elaborate on the key findings of the preclinical data published in Cancer Immunology Research? How significant are the results in terms of advancing TCR-T cell therapy and AMP immunotherapy for the treatment of solid tumours? In this study , we demonstrated that AMP immunotherapy can boost TCR-T cell therapy by acting directly in the lymph nodes to promote the coordination of tumour-specific T cell responses by antigen presenting cells.

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CDC Shortens Recommended COVID Isolation Period

Drugs.com

FRIDAY, March 1, 2024 -- New guidance issued Friday by the U.S. Centers for Disease Control and Prevention recommends that Americans who test positive for COVID-19 no longer need to routinely stay home for five days. Instead, the CDC recommends.

Disease 111
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Live from SCOPE 2024: Talk of the Towne featuring Rare Patient Voice

Antidote

We’re here with Antidote’s tenth installment of Talk of the Towne, and it’s a very special one! We recently attended SCOPE 2024, where we met up with our partners at Rare Patient Voice and recorded our first Talk of the Towne episode live and in person.

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Gritstone to lay off 40% of workforce after costly study delay

BioPharma Drive: Drug Pricing

The restructuring comes ahead of a key study readout for Gritstone, which, like Moderna, is developing a type of personalized vaccine for cancer.

Vaccine 117
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Gamma delta T cells: a rising star in cancer therapy

Drug Target Review

Over the past 25 years, T-cell therapies have gained significant ground in the treatment of cancer. While the spotlight has been firmly fixed on chimeric antigen receptor T (CAR-T) cells and other cell therapies based on alpha beta (αβ) T cells, another subpopulation of T cells – the gamma delta T (γδ T) cell – also holds immense promise against cancer.

Therapies 105
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Is It Allergies or Sinusitis? Many Folks Are Misdiagnosed

Drugs.com

WEDNESDAY, Feb. 28, 2024 -- What if you'd been treated for years for a condition, only to find out that you'd long ago been misdiagnosed?That's what's happening to a sizable number of Americans who are taking allergy meds (to little effect) when in.

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Tutorial 4 – Microservices – Discovery Client, LoadBalancer Client and Feign Client.

Perficient: Drug Development

Read the other blogs in this series: Tutorial 01 – Microservices Architectural Design by using Spring Boot Tutorial 02 – Spring Cloud – Netflix Eureka Server Tutorial 03 – Publish Microservices to the Eureka Server / Blogs / Perficient In the Eureka Server environment, 3 “Client Component” types are possible: Discovery Client Component ( Legacy, No Support for Load Balancing ).

Packaging 104
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The Golgi organelle's ribbon structure is not exclusive to vertebrates, contrary to previous consensus

Science Daily: Pharmacology News

Researchers report that the Golgi ribbon, an organelle structure previously thought to be exclusive to vertebrates, is also present in animal taxa, including mollusks, earthworms, and sea urchins. The function of the Golgi ribbon is still enigmatic, but its presence in diverse animal lineages indicates that its function is not vertebrate specific, as previously thought.

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How CDMO Wacker Biotech is inspiring innovation in mRNA therapeutics

Fierce BioTech

mRNA innovation is one of the most exciting and impactful areas of healthcare globally today. | Sitting down with Guido Seidel, Managing Director of Wacker Biotech, we explore some of the key challenges, opportunities and innovations for pharmaceutical companies to consider in mRNA manufacturing.

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Service Dogs May Lessen Seizure Frequency in Folks With Epilepsy

Drugs.com

THURSDAY, Feb. 29, 2024 -- Perhaps by reducing anxiety, a service dog can help reduce seizures in people with tough-to-treat epilepsy, a new study finds.A group of 25 study participants had an average 31% fewer seizures after months of owning a.

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Uploading blobs to Optimizely DXP via PowerShell

Perficient: Drug Development

We had a client moving from an On-Prem v11 Optimizely instance to DXP v12 and we had a lot of blobs (over 40 GB) needing uploading to DXP as a part of the conversion. This was my first experience doing both a version and environment upgrade and I leaned heavily on Optimizely support to help me get it right. Along the way, I wrote down each step so that I could reference it for any future projects that were doing the same.

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Ice shell thickness reveals water temperature on ocean worlds

Science Daily: Pharmacology News

Astrobiologists have devised a novel way to determine ocean temperatures of distant worlds based on the thickness of their ice shells, effectively conducting oceanography from space.

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