Drug Discovery World
JULY 29, 2022
Australian researchers based may be a step closer to preventing Type 1 diabetes after identifying a crucial protein that could prevent the autoimmune disease from taking hold. Mater Research and University of Queensland researchers have developed a biological agent, sRAGE, that boosts white blood cell function which is damaged in individuals who develop Type 1 diabetes.
Drug Discovery Today
JULY 29, 2022
Geneva-based event pledges five Swiss francs per visitor to support new drug development project
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Drug Channels
JULY 29, 2022
This week, I’m rerunning some popular posts while I prepare for today's live video webinar: Specialty Drugs Update: Trends, Controversies, and Outlook. Note that the forecasts below did not account for policy changes that could further reduce pharmaceuticals' share of U.S. healthcare spending. Click here to see the original post from April 2022.
Antidote
JULY 25, 2022
Atopic dermatitis is a type of eczema, a skin condition caused by an overactive immune system that can lead to redness, blotchiness, and itching, typically on the face, arms, and legs. Atopic dermatitis is the most common type of eczema , impacting more than 9.6 million children and 16.5 million adults worldwide.
Advertisement
Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.
Drug Discovery World
JULY 29, 2022
From immunity to metabolism to mental health, it seems like the gut microbiome has been linked to every aspect of human health and disease. But with hundreds of bacterial species populating our gastrointestinal tract, it’s a daunting task to pinpoint which molecules made by which bacteria affect which biological processes—and how they do so. “Microbiome studies need to move from making associations to determining function and causation,” said Ramnik Xavier, the Kurt J.
Advarra
JULY 26, 2022
Cannabis use has become widespread. As such, we are seeing an uptick in research examining the therapeutic effects of cannabis and its constituents. Currently, cannabis use is legal across many states in the U.S., with 37 states approving medicinal use and 18 approving recreationally. However, it’s not legal federally and is considered a Schedule I drug by the U.S.
Drug Discovery Digest brings together the best content for drug research and development professionals from the widest variety of industry thought leaders.
Antidote
JULY 27, 2022
Kidney diseases are one of the top causes of death in the United States , and worldwide, they impact nearly 10% of the population each year. Because chronic kidney disease typically has no cure, it is vital that medical research takes place to find new and more effective treatments for those who have been diagnosed.
Drug Discovery World
JULY 28, 2022
The world of work has changed since Covid for employees and employers in biotech. Singular Talent is carrying out a research survey to determine what the biotech landscape will look like in future years. It would like your views on attitudes and approaches in working in the biotech sector. Early predictions are that work may transition to be centred on social and learning & development hubs.
Drug Discovery Today
JULY 29, 2022
Registration is open for the UK’s largest trade show for the lab industry
Drug Channels
JULY 25, 2022
This week, I’m rerunning some popular posts while I prepare for this Friday’s live video webinar: Specialty Drugs Update: Trends, Controversies, and Outlook. Click here to see the original post from April 2022. The highly-consolidated PBM market notched another year of increased concentration. Consider Drug Channels Institute's latest estimates of pharmacy benefit manager (PBM) market share, shown in the chart below.
Advertisement
Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.
Antidote
JULY 29, 2022
The process of getting a new drug to market is an expensive one. Between 2009 and 2018, U.S. biopharmaceutical companies spent about $1 billion per drug according to an analysis published in JAMA , and other studies have found that it can cost up to $2.8 billion to bring a new therapy to market. In 2019 alone, research and development spending totaled $186 billion for the global pharmaceutical industry.
Drug Discovery World
JULY 28, 2022
Researchers at the Francis Crick Institute in the UK, have shown that a specific area of the SARS-CoV-2 spike protein is a promising target for a pan-coronavirus vaccine that could offer some protection against new virus variants, common colds, and help prepare for future pandemics. Developing a vaccine that provides protection against a number of different coronaviruses is a challenge because this family of viruses have many key differences, frequently mutate and generally induce incomplete pro
Drug Patent Watch
JULY 29, 2022
Annual Drug Patent Expirations for BEYAZ Beyaz is a drug marketed by Bayer Hlthcare and is included in one NDA. It is available from two suppliers. There are three patents…. The post New patent expiration for Bayer Hlthcare drug BEYAZ appeared first on DrugPatentWatch - Make Better Decisions.
Drug Channels
JULY 27, 2022
This week, I’m rerunning some popular posts while I prepare for this Friday’s live video webinar: Specialty Drugs Update: Trends, Controversies, and Outlook. Click here to see the original post from May 2022. In Drug Channels Institute’s list of the top 15 pharmacies of 2021 , we show that central-fill, mail pharmacies operated by large PBMs and health insurers have displaced retail chains as the largest prescription drug dispensers by revenues.
Advertisement
Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic
Antidote
JULY 28, 2022
Alexis Smith had eczema as an infant, but had lived a mostly itch-free childhood until hitting puberty at 12. That's when her symptoms came back.
Drug Discovery World
JULY 27, 2022
Biotechnology company Recursion has been granted an Orphan Drug Designation for its potential treatment of the rare disease familial adenomatous polyposis (FAP). . FAP is a rare tumour syndrome in which hundreds or thousands of precancerous colorectal polyps grow in the body. As it stands there are no approved therapies for the disease. . Recursion’s therapy REC-4881 is an orally bioavailable non-ATP-competitive allosteric small molecule inhibitor of MEK1 and MEK2 being developed to reduce p
Drug Patent Watch
JULY 29, 2022
Annual Drug Patent Expirations for VASCEPA Vascepa is a drug marketed by Amarin Pharms and is included in one NDA. It is available from two suppliers. There are sixty-eight patents…. The post New patent for Amarin Pharms drug VASCEPA appeared first on DrugPatentWatch - Make Better Decisions.
Drug Channels
JULY 26, 2022
This week, I’m rerunning some popular posts while I prepare for this Friday’s live video webinar: Specialty Drugs Update: Trends, Controversies, and Outlook. ICYMI, the unimplemented rule to reform rebates in Medicare Part D remains the ultimate budget gimmick. More than $122 billion in "savings" (offsets) from the current drug pricing reconciliation legislation comes from blocking rebate reform—which never even happened.
Broad Institute
JULY 29, 2022
Group tour information By Maria Nemchuk July 29, 2022 Breadcrumb Home Group tour information Welcome Exhibits Plan your visit Book a group tour The Broad Discovery Center offers guided tours to visitors Monday - Wednesday at 11:00 AM, unless otherwise posted. Visitors should gather at the S-shaped sofa in the lobby. Reservations are not required for small groups, but are available to visitors interested in a short, guided experience.
Drug Discovery World
JULY 27, 2022
The size of tumour and immune cell populations and their interactions over time impact outcomes to treatment. Immunotherapies that activate the immune system to seek and kill cancer cells have greatly improved outcomes for many patients with solid tumours. There is still, however, a subset of patients who do not see benefit from this type of therapy.
Drug Patent Watch
JULY 29, 2022
Annual Drug Patent Expirations for OTIPRIO Otiprio is a drug marketed by Alk Abello and is included in one NDA. It is available from one supplier. There are seven patents…. The post New patent for Alk Abello drug OTIPRIO appeared first on DrugPatentWatch - Make Better Decisions.
The Connected Lab
JULY 29, 2022
Biobanks play a crucial role in effectively managing and storing critical scientific data: biospecimens. For pharma and biotech companies, diagnostic laboratories, and contract research organizations, specimen integrity is critical to ensure robust and reproducible results. Thermo Scientific™ SampleManager LIMS™ software’s Biorepository Solution is an implementation and validation accelerator which uses industry-standard features, expertise and experience to expedite return on investment and red
Crown Bioscience
JULY 29, 2022
Drug attrition rates remain high, and this has been attributed in part to the poor translatability of current preclinical data. Models that have higher predictivity of patient response are needed.
Drug Discovery World
JULY 26, 2022
Pharmaceutical company BioNTech will deliver the 2022 César Milstein Lecture on 26 July with a focus on how messenger RNA (mRNA) technology can be used within vaccines for cancer and Covid-19. . The lecture will be delivered in two halves by U?ur ?ahin and Özlem Türeci, co-founders of BioNtech. . The first half of the lecture, titled ‘mRNA Cancer Vaccines’ will be delivered by U?
Drug Patent Watch
JULY 29, 2022
Annual Drug Patent Expirations for LOCAMETZ Locametz is a drug marketed by Aaa Usa Novartis and is included in one NDA. It is available from one supplier. The generic ingredient…. The post New patent for Aaa Usa drug LOCAMETZ appeared first on DrugPatentWatch - Make Better Decisions.
Advarra
JULY 28, 2022
Institutional biosafety committees (IBCs) frequently receive questions about the proper type of hood for use with biological materials and the difference between biosafety cabinets versus clean benches. While both pieces of equipment are hoods with directional airflow, they function differently and are intended for different purposes. This article explores how these tools work and why biosafety cabinets are preferred in research involving cell and gene therapies.
Broad Institute
JULY 26, 2022
Researchers decipher how a gut bacterium influences immunity By Corie Lok July 26, 2022 Breadcrumb Home News Researchers decipher how a gut bacterium influences immunity Study finds a molecule made by the bacterium that helps moderate immune responses. By Stephanie Dutchen, Harvard Medical School Office of Communications and External Relations July 26, 2022 Credit: Susanna Hamilton, Broad Communications From immunity to metabolism to mental health, it seems like the gut microbiome has been linke
Drug Discovery World
JULY 26, 2022
Dr Boris Minev, President of Medical and Scientific Affairs at Calidi Biotherapeutics speaks to DDW’s Reece Armstrong about the company’s approach to treating cancer. RA : Could you give us an idea of your current pipeline? BM: Calidi Therapeutics’ current pipeline consists of oncolytic virus-based immunotherapies potentiated by allogeneic stem cells and designed to treat patients for whom few, if any, effective treatment options exist.
Drug Patent Watch
JULY 29, 2022
Annual Drug Patent Expirations for VOQUEZNA+TRIPLE+PAK Voquezna Triple Pak is a drug marketed by Phathom and is included in one NDA. The generic ingredient in VOQUEZNA TRIPLE PAK is amoxicillin;…. The post New patent for Phathom drug VOQUEZNA TRIPLE PAK appeared first on DrugPatentWatch - Make Better Decisions.
Advarra
JULY 27, 2022
As a pharmaceutical product makes its way through the lifecycle, there are often Food and Drug Administration (FDA) guidelines organizations should pay particular attention to. Recent new guidance, “ Q12 Technical and Regulatory Considerations for Pharmaceutical Product Lifecycle Management Guidance for Industry, Center for Drug Evaluation and Research (CDER) Center for Biologics Evaluation and Research (CBER) May 2021 ICH ” now applies to pharmaceutical drug substances and products (both chemic
Broad Institute
JULY 26, 2022
Learning resources By Maria Nemchuk July 26, 2022 Breadcrumb Home Learning resources We are openly sharing our free classroom materials and more for formal and informal STEM educators. Through curriculum guides, explainers, researcher profiles, and more, we aim to support educators as they work to inspire the next generation of biologists, chemists, data scientists, and engineers.
Drug Discovery World
JULY 26, 2022
This is the latest episode of the free DDW podcast, “Now is the time for the transformation of clinical trials”. It covers two narrated articles written for Volume 22, Issue 4 – Fall 2021 of DDW. They are called “Clinical trials, the pandemic and technology” and “Pharma and the benefits of Real World Data ”. . In the first article, Chris Sigley, CEO of Arkivum, says the transformation of clinical trials demands a transformed approach to trial data.
Drug Patent Watch
JULY 28, 2022
Annual Drug Patent Expirations for VOQUEZNA+TRIPLE+PAK Voquezna Triple Pak is a drug marketed by Phathom and is included in one NDA. The generic ingredient in VOQUEZNA TRIPLE PAK is amoxicillin;…. The post New patent for Phathom drug VOQUEZNA TRIPLE PAK appeared first on DrugPatentWatch - Make Better Decisions.
Crown Bioscience
JULY 26, 2022
High-content analysis (HCA) is a powerful approach for drug discovery and drug validation studies, especially when combined with highly clinically relevant 3D in vitro organoids. Combining these technologies allows you to develop comprehensive cellular profiles of how your compounds are affecting cellular systems and spatial biology. As some researchers may be cautious in employing HCA due to the complexities of the technology and downstream analyses, in this post we provide a brief overview of
Expert insights. Personalized for you.
130 
Let's personalize your content