How parenthood may help keep your brain young
Science Daily: Pharmacology News
FEBRUARY 26, 2025
Researchers find that parents show patterns of brain connectivity that oppose age-related changes.
Sat.Feb 22, 2025 - Fri.Feb 28, 2025
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Discovery of Elironrasib (RMC-6291), a Potent and Orally Bioavailable, RAS(ON) G12C-Selective, Covalent Tricomplex Inhibitor for the Treatment of Patients with RAS G12C-Addicted Cancers
Covalent Modifiers
FEBRUARY 25, 2025
James Cregg, Kristof Pota, Aidan C. A. Tomlinson, Jason Yano, Abby Marquez, Yang Liu, Christopher J. Schulze, Kyle J. Seamon, Matthew Holderfield, Xing Wei, Yongxian Zhuang, Yu Chi Yang, Jingjing Jiang, Yue Huang, Ruiping Zhao, Yun Ling, Zhican Wang, Michael Flagella, Zhengping Wang, Mallika Singh, John E. Knox, Robert Nichols, David Wildes, Jacqueline A.
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Pfizer names Patrizia Cavazzoni, former top FDA official, as chief medical officer
BioPharma Drive: Drug Pricing
FEBRUARY 24, 2025
Cavazzoni stepped down from her role as head of the FDA’s main drug review office in mid-January. She will succeed Aida Habtezion.
Why brain cancer is often resistant to immunotherapy
Broad Institute
FEBRUARY 26, 2025
Why brain cancer is often resistant to immunotherapy By Allessandra DiCorato February 26, 2025 Breadcrumb Home Why brain cancer is often resistant to immunotherapy Researchers find four coordinated gene expression programs in immune cells from glioma tumors, including two that could lead to immunotherapy resistance. By Allessandra DiCorato February 26, 2025 Credit: Case courtesy of Dr.
Bridging Innovation & Patient Care: The Growing Role of AI
Speaker: Simran Kaur, Co-founder & CEO at Tattva.Health
AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!
Trying to be happy makes us unhappier by zapping our self-control, study finds
Science Daily: Pharmacology News
FEBRUARY 27, 2025
A new study finds people who habitually try to be happier also tend to have less willpower.
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Regeneron gene therapy helps deaf children hear in small study
BioPharma Drive: Drug Pricing
FEBRUARY 25, 2025
Ten of 11 children born with a rare form of congenital hearing loss experienced improvements after receiving the company’s treatment, new data show.
Identification of Covalent Cyclic Peptide Inhibitors Targeting Protein–Protein Interactions Using Phage Display
Covalent Modifiers
FEBRUARY 25, 2025
Sijie Wang, Franco F. Faucher, Matilde Bertolini, Heeyoung Kim, Bingchen Yu, Li Cao, Katharina Roeltgen, Scott Lovell, Varun Shanker, Scott D. Boyd, Lei Wang, Ralf Bartenschlager, and Matthew Bogyo Journal of the American Chemical Society 2025 DOI: 10.1021/jacs.4c15843 Peptide macrocycles are promising therapeutics for a variety of disease indications due to their overall metabolic stability and potential to make highly selective binding interactions with targets.
New device could allow you to taste a cake in virtual reality
Science Daily: Pharmacology News
FEBRUARY 28, 2025
Novel technology intends to redefine the virtual reality experience by expanding to incorporate a new sensory connection: taste.
Ozempic, Wegovy Linked To Potential Vision Loss
Drugs.com
FEBRUARY 24, 2025
MONDAY, Feb. 24, 2025 -- People taking the weight-loss drug semaglutide could be at a slightly increased risk for a potentially blinding eye condition that affects the optic nerve, a new study says.Patients on semaglutide (Ozempic, Wegovy) had a.
From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience
Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.
The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven
Drug compounders sue FDA over declaration ending Wegovy shortage
BioPharma Drive: Drug Pricing
FEBRUARY 25, 2025
Telehealth provider Hims & Hers said it will tell consumers they need to seek “alternative options on the commercial dosing,” but in earnings Monday still forecast higher revenue and profits in 2025.
A Buyer’s Guide for Scientific Data Management Platforms
Collaborative Drug
FEBRUARY 26, 2025
Analysis of Total Cost of Ownership across leading biotech R&D software lab data management platforms including CDD Vault, Benchling and Dotmatics.
Novel bone marrow transplant can cure sickle cell disease, study suggests
Science Daily: Pharmacology News
FEBRUARY 25, 2025
A bone marrow transplant process is safe and curative for adults with sickle cell disease, according to results of a trial completed at about 20 cancer centers.
Severe Flu Season Raises Concerns About Brain Complications in Kids
Drugs.com
FEBRUARY 28, 2025
FRIDAY, Feb. 28, 2025 -- As this year’s severe flu season rages across the country, federal health officials are investigating a rise in rare but life-threatening brain complications in children. The U.S. Centers for Disease Control and.
How Machine Learning Drives Clinical Trial Efficiency
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Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.
FDA meeting on flu vaccine composition is canceled
BioPharma Drive: Drug Pricing
FEBRUARY 27, 2025
The meeting, which helps the FDA give guidance to vaccine makers on which flu strains to target, is the second to be disrupted since Robert F. Kennedy Jr. was sworn in as health secretary.
Available for Preorder: The 2025 Economic Report on U.S. Pharmacies and Pharmacy Benefit Managers
Drug Channels
FEBRUARY 26, 2025
On March 18, 2025, Drug Channels Institute will release The 2025 Economic Report on U.S. Pharmacies and Pharmacy Benefit Managers. This reportour sixteenth editionremains the most comprehensive, fact-based tool for understanding the entire U.S. drug pricing, reimbursement, and dispensing system. This unique, encyclopedic resource is your ultimate guide to the complex web of interactions within U.S. prescription drug channels. 12 chapters, 500+ pages, 267 exhibits, nearly 1,200 endnotes: There is
Morphing robot turns challenging terrain to its advantage
Science Daily: Pharmacology News
FEBRUARY 26, 2025
A bioinspired robot can change shape to alter its own physical properties in response to its environment, resulting in a robust and efficient autonomous vehicle as well as a fresh approach to robotic locomotion.
Second Flu Vaccine Meeting Canceled -- What Happens Next?
Drugs.com
FEBRUARY 27, 2025
THURSDAY, Feb. 27, 2025 -- A federal vaccine advisory panel work session focused on next year's flu shot has been canceled without explanation. It is the second vaccine advisory meeting that has been canceled or postponed since Robert F. Kennedy.
Deliver Fast, Flexible Clinical Trial Insights with Spotfire
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Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.
FDA brings back some fired device office staff
BioPharma Drive: Drug Pricing
FEBRUARY 24, 2025
An industry source said “most, if not all” of the people at CDRH who were recently dismissed are now being asked to return.
An ancient RNA-guided system could simplify delivery of gene editing therapies
Broad Institute
FEBRUARY 27, 2025
An ancient RNA-guided system could simplify delivery of gene editing therapies By Corie Lok February 27, 2025 Breadcrumb Home An ancient RNA-guided system could simplify delivery of gene editing therapies The programmable proteins are compact, modular, and can be directed to modify DNA in human cells. By Jennifer Michalowski, McGovern Institute February 27, 2025 Credit: Max Wilkinson The Tas protein uses an RNA guide to recognize a specific target DNA sequence.
Hormones may have therapeutic potential to prevent wrinkles, hair graying
Science Daily: Pharmacology News
FEBRUARY 25, 2025
Hormones may be leveraged to treat and prevent signs of aging such as wrinkles and hair graying, according to a new study.
No Suicide Risk Associated With GLP-1 Drugs
Drugs.com
FEBRUARY 28, 2025
FRIDAY, Feb. 28, 2025 -- GLP-1 drugs like Ozempic/Wegovy dont increase a persons risk of suicidal actions or thoughts, a new study has concluded.Earlier research had potentially linked these drugs -- which are used to treat type 2 diabetes and obe.
Clinical Data Like You´ve Never Seen It Before: Why Spotfire Is the Leading Tool for Clinical Analytics
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Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic
Partnering for success in early phase clinical development
BioPharma Drive: Drug Pricing
FEBRUARY 24, 2025
Early-phase clinical trials, including phase 1 and some phase 2a studies, serve as a pivotal step for biotech companies, laying the foundation for a drug candidate’s journey to market.
In Uncertain Times, Good Compliance and Quality Communication Habits Can Offer a Port in the Storm
FDA Law Blog: Biosimilars
FEBRUARY 26, 2025
By John W.M. Claud The ongoing DOGE-led reductions to the federal workforce and recent sweeping policy changes have spawned many questions for compliance officers and quality managers in FDA-regulated companies. How will the cuts at FDA impact inspections and enforcement? Will there be a heightened appetite for mergers and acquisitions in the space?
'Smarts' count: Evolution of intelligence
Science Daily: Pharmacology News
FEBRUARY 25, 2025
The Beatles said it best: Love is all you need. And according to new research, the same may be true in the animal kingdom. Well, at least for mosquitofish -- a matchstick-sized fish endemic to Central America and now found globally. According to the scientists, male mosquitofish possess impressive problem-solving skills and can successfully navigate mazes and other tests.
Opioids During Surgery Might Cause Worse Pain For Patients
Drugs.com
FEBRUARY 27, 2025
THURSDAY, Feb. 27, 2025 -- Powerful synthetic opioids are meant to serve as painkillers, but new research suggests their use during surgery might actually prompt worse pain during patients recovery.The use of two types of synthetic opioid during s.
Leqembi, after delay, gets back on track toward EU approval
BioPharma Drive: Drug Pricing
FEBRUARY 28, 2025
European regulators “reaffirmed” a positive view of Eisai and Biogen’s Alzheimer’s drug after conducting a new safety review.
Drafting Drug Patent Applications for Biologic Drugs
Drug Patent Watch
FEBRUARY 26, 2025
The Complex World of Biologic Drugs: Navigating Patent Applications As a biotech professional, you're likely no stranger to the intricacies of developing life-changing treatments. But have you ever stopped to think about the patent landscape surrounding biologic drugs? It's a complex world, to say the least. Biologic drugs, also known as biologics, are a type of medication made from living organisms or their components.
Bottling a mouse 'superpower' may heal lungs damaged by premature birth
Science Daily: Pharmacology News
FEBRUARY 24, 2025
Using a four-dimensional microscopy technique, researchers have created 3D video images of mouse lung tissue grown in the laboratory. What they have learned has been nothing short of groundbreaking.
Listeria Outbreak From Frozen Shakes Kills 12, Sickens 38
Drugs.com
FEBRUARY 25, 2025
TUESDAY, Feb. 25, 2025 -- A listeria outbreak tied to frozen shakes served in hospitals and long-term care facilities has sickened at least 38 people and killed 12, according to the U.S. Food and Drug Administration (FDA). The shakes, which are not.
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