Forbes: Drug Truths
NOVEMBER 14, 2023
Ultimately, these drugs will also lower the nation’s healthcare bill. They should be made available to all who need them. Insurance companies need to make this happen as soon as possible.
Science Daily: Pharmacology News
NOVEMBER 13, 2023
Researchers aiming to combat rising global temperatures have developed a new 'cooling glass' that can turn down the heat indoors without electricity by drawing on the cold depths of space. The new technology, a microporous glass coating, can lower the temperature of the material beneath it by 3.5 degrees Celsius at noon, and has the potential to reduce a mid-rise apartment building's yearly carbon emissions by 10 percent.
Antidote
NOVEMBER 14, 2023
For Carla Greenbaum, M.D., growing up in the era of space travel and the moon landing kindled a lifelong interest in science. That interest influenced her career trajectory, and she’s now a leading investigator at Benaroya Research Institute where she has studied the natural history of type 1 diabetes (T1D) since 2000. Her work focuses on finding the cause of autoimmunity and developing targets for treatment, which she finds “incredibly exciting and inspiring—like landing on the moon!
Drug Target Review
NOVEMBER 17, 2023
NK cells are among the front line of protection from infected and abnormal cells as part of the ‘innate immune response’. They recognise ‘cell stress molecules’ on the surface of infected, old, injured and cancerous cells without the need for complex pre-stimulation signals of the adaptive immune system (eg, T cells). They do not induce ‘graft versus host’ disease when transplanted for allogeneic therapy and there appears little sign of immune rejection.
Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.
The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven
Broad Institute
NOVEMBER 14, 2023
#WhyIScience Q&A: A computational biologist uses physics to find hidden patterns in cells By Allessandra DiCorato November 14, 2023 Breadcrumb Home #WhyIScience Q&A: A computational biologist uses physics to find hidden patterns in cells Niranj Chandrasekaran talks about his work developing a large image-based cell profiling dataset and his long-standing fascination with physics and astronomy.
NIOSH Science Blog: Drugs
NOVEMBER 13, 2023
One hundred years ago, farmers, loggers, and fishermen turned to their families and communities for advice on safety, health, production, and repairs. They may have even consulted the Farmer’s Almanac or asked a cooperative extension agent. Although family, friends, print media, and extension agents are still great sources of information, the farmers, loggers, and fishermen of this century also began to use smart phones to find answers.
Drug Discovery Digest brings together the best content for drug research and development professionals from the widest variety of industry thought leaders.
Drugs.com
NOVEMBER 14, 2023
TUESDAY, Nov. 14, 2023 -- Paxlovid helps prevent severe COVID-19, but it also might significantly increase a person’s risk of a rebound case, a new study confirms.
Broad Institute
NOVEMBER 13, 2023
Gerstner Center for Cancer Diagnostics receives additional commitment from Louis V. Gerstner, Jr., to advance technologies that could transform cancer care By Leah Eisenstadt November 14, 2023 Breadcrumb Home Gerstner Center for Cancer Diagnostics receives additional commitment from Louis V. Gerstner, Jr., to advance technologies that could transform cancer care Commitment of $20 million will propel efforts to develop, optimize, and demonstrate liquid biopsy technology along with other cancer di
BioPharma Drive: Drug Pricing
NOVEMBER 16, 2023
Clearance of Vertex Pharmaceuticals and CRISPR Therapeutics' Casgevy in the U.K. comes ahead of expected regulatory decisions in the U.S. and Europe.
Antidote
NOVEMBER 17, 2023
Achondroplasia, also known as achondroplastic dwarfism or ACH, is a rare disorder characterized by short stature, a large head, and short arms and legs. It is the most common type of skeletal dysplasia, the umbrella term that identifies hundreds of conditions , and occurs in about one in 15,000 to 35,000 births.
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Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.
Drugs.com
NOVEMBER 17, 2023
WEDNESDAY, Nov. 15, 2023 -- Retatrutide, an experimental weight-loss drug that could compete against blockbusters Wegovy and Zepbound, may work wonders for obese folks with liver disease, new research shows. A wider study, published in June, found.
Perficient: Drug Development
NOVEMBER 13, 2023
If you’re in technology, AIs are everywhere nowadays. At work, I use an AI to help me make proofs of concept, sometimes in communicating with other AIs. At home, I use Google’s Bard to help with those day-to-day mental chores such as meal planning. Even at play, when indulging in some Gran Turismo there’s an AI to race against. I can’t do anything about the AIs I use more casually (aside from being aware of them).
BioPharma Drive: Drug Pricing
NOVEMBER 13, 2023
Forge Biologics operates a contract manufacturing business as well as develops its own gene therapies, which appears to have attracted the Japan-based food and biotechnology company.
addgene Blog
NOVEMBER 13, 2023
Every few months, we highlight a subset of the new plasmids, antibodies, and viral preps in the repository through our Hot Plasmids articles. Today, it's time for another edition of Hot Plasmids!
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Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.
Drugs.com
NOVEMBER 17, 2023
THURSDAY, Nov. 16, 2023 -- The first home test for chlamydia and gonorrhea will soon hit the market, following its approval Wednesday by the U.S. Food and Drug Administration. People will be able to buy the Simple 2 Test over-the-counter at a.
Drug Target Review
NOVEMBER 16, 2023
What is the thesis underlying Recce Pharmaceutical’s approach? Our approach is to combat the increasing global health threat posed by antimicrobial resistance (AMR) by advancing a new class of synthetic anti-infectives with a unique mechanism of action. AMR results from the overuse of antimicrobials, contributing to the development of multi-drug resistant bacterial species, often referred to as superbugs.
BioPharma Drive: Drug Pricing
NOVEMBER 13, 2023
Trial results add to evidence that so-called Factor XIa inhibitors could have less bleeding risk than currently available oral anticoagulants like Xarelto.
Broad Institute
NOVEMBER 15, 2023
Fairness, listening, and learning: A conversation with Broad’s chief equity officer By Corie Lok November 15, 2023 Breadcrumb Home Fairness, listening, and learning: A conversation with Broad’s chief equity officer Just a few weeks into his new position, Kedrick Perry spoke about his approach to diversity, equity, inclusion, and belonging, what his goals are, and what motivates him in his work.
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Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic
Drugs.com
NOVEMBER 14, 2023
MONDAY, Nov. 13, 2023 (Healthday News) -- In a finding that could change the landscape of heart disease care, the wildly popular weight-loss drug Wegovy has proved its mettle in protecting the heart after lowering the risk of cardiac problems in.
Drug Target Review
NOVEMBER 15, 2023
Drug discovery is an interdisciplinary process that relies heavily on expert input from diverse and multifaceted teams, from medicinal, synthetic, and computational chemists to biologists and drug metabolism and pharmacokinetics (DMPK) scientists. Each team supplies valuable insights throughout the design-make-test-analyse (DMTA) cycle to enable the effective design and optimisation of high-calibre drug candidates.
BioPharma Drive: Drug Pricing
NOVEMBER 15, 2023
Since halting work on a sickle cell treatment early this year, Graphite Bio has laid off staff, shed assets and, now, agreed to be subsumed via a merger with Lenz Therapeutics.
Drug Patent Watch
NOVEMBER 17, 2023
Researchers from West Virginia University College of Law have conducted a study examining the frequency of drug patent invalidations based on inequitable conduct. The findings, published in JAMA, shed light… The post Navigating Legal Waters: Study Delves into Inequitable Conduct in Drug Patent Cases appeared first on DrugPatentWatch - Make Better Decisions.
Drugs.com
NOVEMBER 14, 2023
MONDAY, Nov. 13, 2023 -- Cutting out just one teaspoon of salt every day lowers blood pressure almost as much as medication does, new research shows. Investigators said theirs is one of the largest studies ever to include people taking high blood.
Drug Target Review
NOVEMBER 13, 2023
Regulatory T cells (Treg) cells are specialised immune cells that are essential for maintaining peripheral tolerance, preventing autoimmune diseases, and limiting chronic inflammatory diseases. However, they also limit beneficial responses by suppressing sterilising immunity and limiting antitumour immunity. 1 Understanding how they work is crucial for determining how they may be manipulated to encourage the destruction of cancer cells or prevent autoimmunity.
BioPharma Drive: Drug Pricing
NOVEMBER 13, 2023
Regulatory agencies have set the framework and use cases for RWE. How can these increase the probability of success or efficiency in a pre-clinical and clinical drug development program?
Perficient: Drug Development
NOVEMBER 14, 2023
Troubleshooting image update issues in Sitecore can prove to be a complex task, as various factors could contribute to the problem. We recently encountered an issue where, after updating the “Sitecore Images,” our local project instance stopped working. In order to resolve the issue, we attempted multiple possible solutions, including those available on the internet, but initially were not able to identify the root cause of the problem.
Drugs.com
NOVEMBER 17, 2023
THURSDAY, Nov. 16, 2023 -- Shrinkage of one of the brain's key memory centers appears to herald thinking declines, a new study finds. The region in question is the hippocampus, a two-sided structure located roughly above each ear and embedded deep.
Drug Target Review
NOVEMBER 17, 2023
NK cells are among the front line of protection from infected and abnormal cells as part of the ‘innate immune response’. They recognise ‘cell stress molecules’ on the surface of infected, old, injured and cancerous cells without the need for complex pre-stimulation signals of the adaptive immune system (eg, T cells). They do not induce ‘graft versus host’ disease when transplanted for allogeneic therapy and there appears little sign of immune rejection.
biobide
NOVEMBER 11, 2023
Derived from the tobacco plant Nicotiana, nicotine is a naturally occurring alkaloid that can be an extremely addictive stimulant. If consumed persistently it can contribute to long-term pathologies and could terminate in death. However, it can potentially have benefits when under medical use.
BioPharma Drive: Drug Pricing
NOVEMBER 16, 2023
Acquired via a $4 billion biotech buyout, Augtyro is one of an array of new products the pharma hopes will offset patent expirations for current top sellers.
Drugs.com
NOVEMBER 17, 2023
WEDNESDAY, Nov. 14, 2023 -- Oral nicotine pouches might be marketed as an alternative to cigarettes, but they do little to curb smokers’ nicotine cravings, a new study finds. The pouches – which contain nicotine powder and other.
PLOS: DNA Science
NOVEMBER 16, 2023
After a long career as a science writer, textbook author, and genetic counselor, I’ve become an accidental authority on squashes. I began volunteering at the largest food pantry in my small city in June 2020, where my husband Larry had been in charge of the plant and fungal kingdoms for years. It was the height of the pandemic. So gloved and masked, we shoved fruits and veggies into plastic bags, filled shopping carts with the bags, and wheeled them over to a window at which another masked
Perficient: Drug Development
NOVEMBER 15, 2023
Perficient’s Generative AI Lab, part of our larger Generative AI Innovation Group, is consistently exploring and implementing use cases for generative AI and helping clients operationalize it with policies, advocacy, controls, and enablement. One use case organizations can consider is augmented research for sales prospecting, which allows sales professionals to find valuable prospects quickly and generate personalized and effective sales reports and outreach content.
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