Sat.Nov 11, 2023 - Fri.Nov 17, 2023

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'Cooling glass' blasts building heat into space

Science Daily: Pharmacology News

Researchers aiming to combat rising global temperatures have developed a new 'cooling glass' that can turn down the heat indoors without electricity by drawing on the cold depths of space. The new technology, a microporous glass coating, can lower the temperature of the material beneath it by 3.5 degrees Celsius at noon, and has the potential to reduce a mid-rise apartment building's yearly carbon emissions by 10 percent.

Research 343
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World’s first CRISPR medicine approved in UK for sickle cell, beta thalassemia

BioPharma Drive: Drug Pricing

Clearance of Vertex Pharmaceuticals and CRISPR Therapeutics' Casgevy in the U.K. comes ahead of expected regulatory decisions in the U.S. and Europe.

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COVID Rebound Occurs in 1 in 5 People Taking Paxlovid

Drugs.com

TUESDAY, Nov. 14, 2023 -- Paxlovid helps prevent severe COVID-19, but it also might significantly increase a person’s risk of a rebound case, a new study confirms.

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Empowering Collaboration in Drug Discovery: CDD Vault and the COVID Moonshot

Collaborative Drug

The collaboration's achievements include the discovery of potent antivirals, building open knowledge bases, and functioning as an information-exchange hub,

Drugs 245
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Bridging Innovation & Patient Care: The Growing Role of AI

Speaker: Simran Kaur, Co-founder & CEO at Tattva.Health

AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!

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Earth's surface water dives deep, transforming core's outer layer

Science Daily: Pharmacology News

A new study has revealed that water from the Earth's surface can penetrate deep into the planet, altering the composition of the outermost region of the metallic liquid core and creating a distinct, thin layer. Illustration of silica crystals coming out from the liquid metal of the Earth's outer core due to a water-induced chemical reaction.

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More Trending

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Experimental Weight-Loss Drug, Retatrutide, Slashed Fat in Livers of Obese People

Drugs.com

WEDNESDAY, Nov. 15, 2023 -- Retatrutide, an experimental weight-loss drug that could compete against blockbusters Wegovy and Zepbound, may work wonders for obese folks with liver disease, new research shows. A wider study, published in June, found.

Drugs 279
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Insurers Should Start Paying For Life-Changing Weight Loss Drugs

Forbes: Drug Truths

Ultimately, these drugs will also lower the nation’s healthcare bill. They should be made available to all who need them. Insurance companies need to make this happen as soon as possible.

Drugs 217
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Solar-powered device produces clean water and clean fuel at the same time

Science Daily: Pharmacology News

A floating, solar-powered device that can turn contaminated water or seawater into clean hydrogen fuel and purified water, anywhere in the world, has been developed by researchers.

Research 273
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Forbion-backed biotech raises $138M to develop ALS drug

BioPharma Drive: Drug Pricing

The Series A round for three-year-old startup VectorY is one of the largest private financings in Europe this year, Forbion said.

Drugs 286
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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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FDA Approves First At-Home Test for Chlamydia, Gonorrhea

Drugs.com

THURSDAY, Nov. 16, 2023 -- The first home test for chlamydia and gonorrhea will soon hit the market, following its approval Wednesday by the U.S. Food and Drug Administration. People will be able to buy the Simple 2 Test over-the-counter at a.

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Real-time monitoring of the reaction of KRAS G12C mutant specific covalent inhibitor by in vitro and in-cell NMR spectroscopy

Covalent Modifiers

Qingci Zhao, Ryoka Haga, Satoko Tamura, Ichio Shimada & Noritaka Nishida Sci Rep 13 , 19253 (2023). [link] KRAS mutations are major drivers of various cancers. Recently, allele-specific inhibitors of the KRAS G12C mutant were developed that covalently modify the thiol of Cys12, thereby trapping KRAS in an inactive GDP-bound state. To study the mechanism of action of the covalent inhibitors in both in vitro and intracellular environments, we used real-time NMR to simultaneously observe GTP hy

Drugs 182
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Realistic talking faces created from only an audio clip and a person's photo

Science Daily: Pharmacology News

A team of researchers has developed a computer program that creates realistic videos that reflect the facial expressions and head movements of the person speaking, only requiring an audio clip and a face photo. DIverse yet Realistic Facial Animations, or DIRFA, is an artificial intelligence-based program that takes audio and a photo and produces a 3D video showing the person demonstrating realistic and consistent facial animations synchronised with the spoken audio (see videos).

Research 267
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Gilead expands Arcellx cancer cell therapy deal

BioPharma Drive: Drug Pricing

The deal gives Gilead an estimated 13% ownership in Arcellx and extends the company’s cash runway into 2027.

Therapies 280
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How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

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Wegovy Cuts Heart Risks by 20% in Large Trial

Drugs.com

MONDAY, Nov. 13, 2023 (Healthday News) -- In a finding that could change the landscape of heart disease care, the wildly popular weight-loss drug Wegovy has proved its mettle in protecting the heart after lowering the risk of cardiac problems in.

Trials 278
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Hot Plasmids - November 2023

addgene Blog

Every few months, we highlight a subset of the new plasmids, antibodies, and viral preps in the repository through our Hot Plasmids articles. Today, it's time for another edition of Hot Plasmids!

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Printed robots with bones, ligaments, and tendons

Science Daily: Pharmacology News

For the first time, researchers have succeeded in printing a robotic hand with bones, ligaments and tendons made of different polymers using a new laser scanning technique. The new technology makes it possible to 3D print special plastics with elastic qualities in one go. This opens up completely new possibilities for the production of soft robotic structures.

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Detailed trial data confirm Wegovy heart benefit

BioPharma Drive: Drug Pricing

As GLP-1 drugs for weight loss take off, the results for Novo Nordisk’s treatment could help convince insurers to expand coverage.

Trials 281
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Deliver Fast, Flexible Clinical Trial Insights with Spotfire

Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

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Major Study Confirms Salt's Deadly Effect on Blood Pressure

Drugs.com

MONDAY, Nov. 13, 2023 -- Cutting out just one teaspoon of salt every day lowers blood pressure almost as much as medication does, new research shows. Investigators said theirs is one of the largest studies ever to include people taking high blood.

Research 264
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Patient perspectives: Clinical trials and Diabetes Awareness Month

Antidote

Each November is designated as Diabetes Awareness Month , an event that highlights the importance of spreading awareness about diabetes and the health issues it can cause.

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US men die 6 years before women, as life expectancy gap widens

Science Daily: Pharmacology News

We've known for more than a century that women outlive men. But new research shows that, at least in the United States, the gap has been widening for more than a decade.

Research 250
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Ajinomoto spices up its biopharma business with gene therapy deal

BioPharma Drive: Drug Pricing

Forge Biologics operates a contract manufacturing business as well as develops its own gene therapies, which appears to have attracted the Japan-based food and biotechnology company.

Therapies 273
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Clinical Data Like You´ve Never Seen It Before: Why Spotfire Is the Leading Tool for Clinical Analytics

Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

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One Part of Your Brain Could Point to the Mind's Decline

Drugs.com

THURSDAY, Nov. 16, 2023 -- Shrinkage of one of the brain's key memory centers appears to herald thinking declines, a new study finds. The region in question is the hippocampus, a two-sided structure located roughly above each ear and embedded deep.

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A researcher's perspective: Linking scientific discovery to clinical medicine

Antidote

For Carla Greenbaum, M.D., growing up in the era of space travel and the moon landing kindled a lifelong interest in science. That interest influenced her career trajectory, and she’s now a leading investigator at Benaroya Research Institute where she has studied the natural history of type 1 diabetes (T1D) since 2000. Her work focuses on finding the cause of autoimmunity and developing targets for treatment, which she finds “incredibly exciting and inspiring—like landing on the moon!

Research 121
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Air cleaners don't stop you getting sick

Science Daily: Pharmacology News

New research shows that air filtration systems or 'air cleaners' don't stop you getting sick. Air cleaners are designed to filter pollutants or contaminants out of the air that passes through them.

Research 247
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West Coast investor Red Tree on its San Diego expansion and staying bullish in biotech

BioPharma Drive: Drug Pricing

Red Tree Venture Capital plans to tap into San Diego’s biotech pipeline as it works to build a West Coast competitor to Boston-area investors.

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Popular 'Nicotine Pouches' Won't Help Smokers Quit: Study

Drugs.com

WEDNESDAY, Nov. 14, 2023 -- Oral nicotine pouches might be marketed as an alternative to cigarettes, but they do little to curb smokers’ nicotine cravings, a new study finds. The pouches – which contain nicotine powder and other.

Marketing 264