DrugBaron

JANUARY 31, 2024

This month’s announcement that Alphabet’s Isomorphic Labs, led by the talented and charismatic Deepmind co-founder Demis Hassabis, had inked discovery collaboration deals with both Lilly and Novartis was just the latest indication that AI-enabled pharma R&D was ready for the big time. Billions of dollars have been invested in companies promising to “revolutionise pharma R&D” through the application of artificial intelligence – but it is now clear that global pharma companies, and not ju

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Drug Discovery World

FEBRUARY 2, 2024

Head of clinical trials at the University College London (UCL) Dementia Research Centre, Dr Cath Mummery, has been announced as the Director of a new network of dementia trial sites across the country. The UK government has authorised £49.9 ($63.4) million of new funding to improve access to clinical trials and help accelerate the development of new treatments.

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National Institute on Drug Abuse: Nora's Blog

FEBRUARY 1, 2024

50 years after founding, NIDA urges following science to move beyond stigma area Thu, 02/01/2024 - 11:20 Nora's Blog February 1, 2024 Image NIDA Image In 2024, NIDA celebrates its 50th anniversary. On May 14, 1974, an act of Congress established the National Institute on Drug Abuse (NIDA), and since then NIDA has led the world in funding and conducting research on drug use and addiction.

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BioPharma Drive: Drug Pricing

JANUARY 30, 2024

Since a landmark paper in 2022, drugmakers have begun nearly a dozen trials of cell therapies for lupus, with more set to start. Here’s why their efforts are worth watching.

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Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

Clinical Trials

Drugs.com

JANUARY 30, 2024

TUESDAY, Jan. 30, 2024 -- The maker of a drug used to treat ADHD and narcolepsy has recalled one lot of the medication after a pill mixup was discovered.The recall notice, issued by Azurity Pharmaceuticals Inc., states that one lot of Zenzedi.

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Drug Discovery World

JANUARY 30, 2024

A UK-based start-up is developing technology to build a pharmaceuticals factory in space that will make antibody treatments more accessible and easier to administer. BioOrbit are aiming to build the first pharmaceuticals factory in microgravity and are currently developing a platform for large-scale crystallisation of protein drugs. As a result of ever-increasing demands on hospitals, there is a need to develop drugs that can be self-administered at home.

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BioPharma Drive: Drug Pricing

JANUARY 29, 2024

The FDA is reviewing the companies’ application for a “tumor agnostic” indication for their drug Enhertu, which would break new ground for antibody-drug conjugates.

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Antidote

FEBRUARY 2, 2024

Endometrial cancer, also known as endometrial carcinoma or uterine cancer , is a condition that approximately 66,000 individuals are diagnosed with annually, and instances rise roughly 2% in the United States each year. Because it is often caught early, a person’s prognosis is typically good — but it is still a disheartening diagnosis that significantly impacts the lives of those who experience it.

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Drug Discovery World

JANUARY 30, 2024

Over the three days of Advanced Therapies Week (ATW) 2024 in Miami, Florida, US, 16-19 January 2024, DDW’s Megan Thomas heard from attendees about the obstacles the sector needs to overcome to succeed. Viral vector manufacturing At the Advanced Therapies Awards ceremony, Dr Luigi Naldini, Director of the San Raffaele Telethon Institute for Gene Therapy, was awarded a Lifetime Achievement Award in recognition of ‘extraordinary contributions to gene therapy’, a field he has helped shape thro

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Science Daily: Pharmacology News

FEBRUARY 1, 2024

It's an achievement with important implications for scientists studying the brain and working on treatments for a broad range of neurological and neurodevelopmental disorders, such as Alzheimer's and Parkinson's disease.

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Clinical Trials

BioPharma Drive: Drug Pricing

JANUARY 30, 2024

The company plans to soon ask the FDA for approval of the drug, which it has pitched as a safer alternative to addictive opioid painkillers.

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Antidote

JANUARY 29, 2024

For individuals living with a condition like melanoma, volunteering to participate in a clinical trial can be a rewarding experience. Not only will patients be able to gain access to potential new treatments, but they will also be directly contributing to research that can save lives — something that Jamie Troil Goldfarb has experienced firsthand. Jamie received a diagnosis of stage IV melanoma in 2011, only 11 weeks after giving birth to her child.

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Drug Discovery World

JANUARY 29, 2024

In the In Conversation With series, a part of the free DDW podcast, DDW speaks with members of the drug discovery industry about their work and how it helps turn science into business. In this episode, Megan Thomas is in conversation with Dr Lynn Kirkpatrick, CEO of Ensysce Biosciences. As we all know, the opioid epidemic is one of the biggest issues in the United States today.

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Science Daily: Pharmacology News

FEBRUARY 2, 2024

Fake news works for wallabies and elephants. Herbivores can cause substantial damage to crops or endangered or protected plants, with traditional methods to deter foraging lethal, expensive or ineffective. Biologists are now using aromas from plants naturally repellent with remarkable success to deter the animals.

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Clinical Trials

Drugs.com

JANUARY 30, 2024

TUESDAY, Jan. 30, 2024 -- The first new kind of pain medication in over two decades could be on the horizon for patients, with promising results announced Tuesday from a company trial. For now, the drug from Vertex Pharmaceuticals is called VX-548.

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Drug Target Review

FEBRUARY 2, 2024

What specific limitations in mirroring diseases in humans are commonly observed when using animal models for preclinical research? The standard animal model paradigm for drug discovery does not translate well to effects in patients for a number of reasons. For one, animal models require disease induction, either genetic or surgical modifications, diet, or application of a disease inducing agent or toxin, yet this is nothing like how diseases progress in humans, which typically take years to deve

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Drug Discovery World

JANUARY 30, 2024

The Winter issue of Drug Discovery World (DDW) is out now and asks whether AI can deliver better immunotherapies for cancer and includes expert predictions on what to expect from the sector in 2024, alongside a supplement looking at SLAS2024 and an exclusive guide exploring therapeutic antibodies. Read the digital version here. Other features in the Winter issue include: A market report on the drug discovery opportunities in Singapore.

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Science Daily: Pharmacology News

FEBRUARY 1, 2024

Researchers have discovered a change in what scientists already knew about global warming dynamics. It had been widely accepted since the 1950s that global temperature rises were not consistent throughout the day and night, with greater nighttime warming being observed. However, the recent study reveals a shift in dynamics: with greater daytime warming taking place since the 1990s.

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Drugs.com

FEBRUARY 1, 2024

THURSDAY, Feb. 1, 2024 -- Certain copycat eyedrops may be contaminated and could give users an antibiotic-resistant eye infection, the U.S. Food and Drug Administration warned Wednesday.The packaging for South Moon, Rebright and FivFivGo eyedrops.

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Packaging FDA Drugs 116

Fierce BioTech

FEBRUARY 2, 2024

The annual J.P. Morgan Healthcare Conference is a key date in the industry calendar that is always met with reflection and anticipation. | In this exclusive interview, ICON Biotech President Chris Smyth paints a picture of the operating environment facing biotechs in 2024.

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Drug Discovery World

JANUARY 30, 2024

DDW is delighted to announce the final speaker on its SLAS2024 Ignite Theater track ‘ Innovation & technology: from lab to patient ’, co-sponsored by Integra Biosciences and Hamamatsu Corporation. Dipanwita Das On Monday 5 February at 11.30am, Dipanwita Das, CEO and Co-founder of Sorcero, will address the question ‘Is pharma’s commercial model dying?

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Science Daily: Pharmacology News

FEBRUARY 1, 2024

Scientists developed a new method to map exactly how a fungus works with leafcutter ants in a complex microbial community to degrade plant material at the molecular level. The team's insights are important for biofuels development.

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Drug Patent Watch

JANUARY 30, 2024

The recent paper published in PLOS ONE presents a novel approach for efficiently retrieving a substantial number of patents related to specific technologies. The authors enhance an automated patent landscaping… The post Revolutionizing Patent Landscaping: A Human-Supervised AI Approach to Identify Tech Clusters appeared first on DrugPatentWatch - Make Better Decisions.

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Drugs.com

JANUARY 30, 2024

TUESDAY, Jan. 30, 2024 -- Opdivo, one of the new generation of immunotherapy cancer treatments, appears to help kidney cancer patients equally well when given as a quick injection versus the current method of intravenous delivery, a new study.

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Drug Discovery World

FEBRUARY 2, 2024

The DDW team is looking forward to meeting you at SLAS2024, Boston, US on 3-7 February. New for this year is the DDW track at the SLAS Ignite Theater , co-sponsored by Integra Biosciences and Hamamatsu Corporation. Industry experts will share their experiences of how drug discovery technology is driving innovation from bench to bedside. The track is free to attend but spaces are limited.

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Science Daily: Pharmacology News

JANUARY 31, 2024

Radon is the second leading cause of lung cancer. Now a new study has found exposure to this invisible, odorless gas is also linked to an increased risk of stroke. The study, which examined exposures in middle age to older female participants, found an increased risk of stroke among those exposed to high and even moderate concentrations of the gas compared to those exposed to the lowest concentrations.

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BioPharma Drive: Drug Pricing

JANUARY 30, 2024

Roche, Pfizer and Bristol Myers Squibb have all invested in the startup, which is using nanoparticle technology to retrain the body’s immune system.

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Drugs.com

JANUARY 29, 2024

MONDAY, Jan. 29, 2024 -- Five of eight British children who received human growth hormone from the pituitary glands of deceased donors went on to develop early-onset Alzheimer's disease many decades later, researchers report.Researchers at.

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Drug Discovery World

FEBRUARY 1, 2024

A paper in BioRxiv has described a new process that could improve the chimeric antigen receptor (CAR) T-cell patient experience and reduce costs through a minimisation of the CAR T-cell therapy vein-to-vein process. The process utilises less than 300ml of whole blood from a blood draw instead of apheresis for the collection of T cells from patients undergoing chimeric antigen receptor CAR T-cell therapy.

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Science Daily: Pharmacology News

JANUARY 30, 2024

A new study may hold a secret for getting your teenager to listen to appreciate your unsolicited advice. The study, which included 'emerging adults' -- those in their late teens and early 20s -- found teens will appreciate parents' unsolicited advice, but only if the parent is supportive of their teens' autonomy.

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BioPharma Drive: Drug Pricing

FEBRUARY 1, 2024

Roche said it was shelving those drugs in favor of experimental programs to treat obesity that it gained from its takeover of Carmot Therapeutics.

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Drugs.com

JANUARY 29, 2024

MONDAY, Jan. 29, 2024 -- Following a recall of millions of its breathing machines that began in mid-2021, Philips Respironics announced Monday that it would halt sales of all such machines within the United States.The machines include continuous.

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Drug Discovery World

JANUARY 29, 2024

Leading experts in genomics, personalised medicine and drug discovery convened at the Precision Medicine Community Event in London to unveil the latest advancements shaping the future of healthcare. The event highlighted critical areas such as secure and diverse data access, genomic sequencing in newborns, building public trust, and global collaboration, setting the stage for transformative developments in precision medicine.

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Science Daily: Pharmacology News

JANUARY 31, 2024

Antimicrobial resistance is an urgent and growing global crisis. Researchers are exploring phages, viruses that infect bacteria, as a possible solution. In the new study, researchers successfully modified DNA from four types of phages to kill a deadly pathogen. The process can also be used to produce more phage variants for further exploration.

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