Drugs.com
JANUARY 8, 2025
WEDNESDAY, Jan. 8, 2025 -- Three GLP-1 drugs are best at helping obese and overweight people drop weight, including one that hasnt yet been approved for that purpose.A new evidence review published in the Annals of Internal Medicine shows that the.
Science Daily: Pharmacology News
JANUARY 8, 2025
Evolutionary biologists are investigating the extent to which ants learn from past experiences. After being attacked by ants from a particular nest, ants behave more aggressively towards others from that same nest.
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Broad Institute
JANUARY 9, 2025
Scientists engineer CRISPR enzymes that evade the immune system By Allessandra DiCorato January 9, 2025 Breadcrumb Home Scientists engineer CRISPR enzymes that evade the immune system The new genome-editing tools could lead to safer, more efficient gene therapies. By Allessandra DiCorato January 9, 2025 Credit: Natalie Velez, Broad Communications Related news Researchers uncover new CRISPR-like system in animals that can edit the human genome The core components of CRISPR-based genome-editing th
BioPharma Drive: Drug Pricing
JANUARY 8, 2025
The regulator is requiring labeling that warns of Guillan-Barré syndrome, although it said data don’t prove a causal link and affirmed the shots’ benefit outweighs their risks.
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Drugs.com
JANUARY 10, 2025
FRIDAY, Jan. 10, 2025 -- Ozempic? Wegovy? Zepbound?How about elderberry juice?Elderberry juice might help people lose weight and improve their blood sugar control, a new small-scale study says.People who drank 12 ounces of elderberry juice daily.
Science Daily: Pharmacology News
JANUARY 10, 2025
A new study has found that the composition of your gut microbiome helps predict how likely you are to succumb to potentially life-threatening infection with Klebsiella pneumoniae, E.coli and other bugs -- and it may be altered by changing your diet.
Drug Discovery Digest brings together the best content for drug research and development professionals from the widest variety of industry thought leaders.
BioPharma Drive: Drug Pricing
JANUARY 7, 2025
Denali’s medicine and a similar one from Calico Life Sciences and AbbVie were not much different than a placebo, bringing the tally of failed drugs in the innovative “Healey platform trial” to seven.
Drugs.com
JANUARY 10, 2025
FRIDAY, Jan. 10, 2025 -- The clock is running for people whove been diagnosed with dementia, but the time they have left depends on their age.Average life expectancy for people with dementia is largely based on their age at diagnosis, researchers f.
Science Daily: Pharmacology News
JANUARY 9, 2025
Hydroclimate whiplash -- rapid swings between intensely wet and dangerously dry weather -- has already increased globally due to climate change, with further large increases expected as warming continues, according to a team of researchers.
Broad Institute
JANUARY 6, 2025
Feng Zhang awarded the National Medal of Technology and Innovation By Corie Lok January 6, 2025 Breadcrumb Home Feng Zhang awarded the National Medal of Technology and Innovation Zhang and 22 other individuals received the USs highest honors for science and technology. By Broad Communications January 6, 2025 Credit: Ryan K. Morris Feng Zhang receives the National Medal of Technology and Innovation at the White House from Arati Prabhakar (left), director of the White House Office of Science and T
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Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.
BioPharma Drive: Drug Pricing
JANUARY 10, 2025
The director of the FDA's main drug review office will exit on Jan. 18, according to an email sent to staff. Her departure is one of several announced by high-ranking FDA leaders ahead of the coming administration change.
Chemical Biology and Drug Design
JANUARY 5, 2025
5(4-Hydroxyphenyl)-2-(N-Phenyl amino)-1,3,4-Oxadiazole (Hppo) can considered as a versatile agent in designing novel pharmaceuticals. ABSTRACT Oxadiazole compounds are of great interest because they have a range of biological activities ranging from antioxidants to anticancer agents. Against this background, we wanted to demonstrate the antioxidant, enzyme inhibitory, and anticancer effects of 5(4-hydroxyphenyl)-2-(N-phenylamino)-1,3,4-oxadiazole (Hppo).
Science Daily: Pharmacology News
JANUARY 10, 2025
The way cricket frogs move across the surface of water has long been thought to resemble walking on water, but researchers have now discovered a different reality.
Drugs.com
JANUARY 9, 2025
THURSDAY, Jan. 9, 2025 -- Over-the-counter (OTC) drugs acetaminophen and ibuprofen are better at managing dental pain than opioids.People who had their wisdom teeth removed got better results from an acetaminophen/ibuprofen combo than with a.
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BioPharma Drive: Drug Pricing
JANUARY 6, 2025
The startup is developing a kind of macrocyles, which share strengths of both small molecules and biologics, as oral medicines against “validated blockbuster biologic targets.
Codon
JANUARY 5, 2025
Today we launch Issue 05 of Asimov Press. Read our full Editors’ Note and preview upcoming articles on our website. Thanks for reading! Edwin Cohn, a temperamental and entrepreneurial protein chemist working at Harvard University in the early 1900s, is perhaps one of the most underrated translational scientists of all time. In 1940, with the likelihood of America’s involvement in World War II steadily rising, the U.S. military approached Cohn about developing medical products from bl
Science Daily: Pharmacology News
JANUARY 10, 2025
A new study based on the sampling and analysis of volcanic ash at Cumbre Vieja volcano in the Canary Islands, located off Africa's northwest coast, suggests that the composition of magma could drive tremors during volcanic eruptions. The findings highlight the potential of volcanic ash analysis as a monitoring and forecasting tool.
Drugs.com
JANUARY 8, 2025
WEDNESDAY, Jan. 8, 2024 -- The antiviral pill Paxlovid might help some patients who are suffering from long COVID.A five-day course of Paxlovid is known to help limit symptoms and shorten illness in patients during an initial bout of COVID-19.
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Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic
BioPharma Drive: Drug Pricing
JANUARY 8, 2025
Alongside plans to spin out a new company, the Belgian drugmaker said it will cut some 300 positions, or about 40% of its current workforce.
Covalent Modifiers
JANUARY 9, 2025
Tomonori Tamura, Masaharu Kawano, and Itaru Hamachi Chemical Reviews 2024 DOI: 10.1021/acs.chemrev.4c00745 The term undruggable refers to proteins or other biological targets that have been historically challenging to target with conventional drugs or therapeutic strategies because of their structural, functional, or dynamic properties. Drugging such undruggable targets is essential to develop new therapies for diseases where current treatment options are limited or nonexistent.
Science Daily: Pharmacology News
JANUARY 9, 2025
A battery that needs feeding instead of charging? This is exactly what researchers have achieved with their 3D-printed, biodegradable fungal battery. The living battery could supply power to sensors for agriculture or research in remote regions. Once the work is done, it digests itself from the inside.
Drugs.com
JANUARY 7, 2025
TUESDAY, Jan. 7, 2025 -- The U.S. Food and Drug Association (FDA) released the first-ever guidelines for levels of lead in processed baby foods this week. However, many health and safety advocates say they are not satisfied with the guidance.Under.
BioPharma Drive: Drug Pricing
JANUARY 9, 2025
The results suggest Bayer’s elinzanetant may help a broader group of women with vasomotor symptoms, which are associated with menopause as well as a common breast cancer therapy.
Plenge Gen
JANUARY 7, 2025
When I last wrote about AI on this blog three years ago, I spoke of it being a tool with the potential to transform scientific discovery, but the application I described was primarily theoretical. For AI to be a meaningful tool in R&D, I argued, we needed better sources of truth better data sets that AI tools could query and learn from over time and technology capable of integrating multiples steps into a semi-automated system.
Science Daily: Pharmacology News
JANUARY 6, 2025
Tuberculosis (TB) is the world's biggest infectious disease killer with multidrug-resistant TB (MDR-TB) posing a particular threat to global health. A study shows that resistance to the new MDR-TB treatment regimen recently recommended by the World Health Organization is already spreading between patients.
Drugs.com
JANUARY 10, 2025
FRIDAY, Jan. 10, 2025 -- The words calm down are worse than unhelpful -- they actually can increase blood pressure among new mothers of color, a study has found.Gender-based racism through such microaggressions significantly increased a new moms.
BioPharma Drive: Drug Pricing
JANUARY 7, 2025
The three-year partnership is another example of Vertex’s interest in improving on Casgevy, its CRISPR medicine for sickle cell and beta thalassemia.
Collaborative Drug
JANUARY 9, 2025
Drug Discovery Industry Roundup with Barry Bunin January 9th, 2025
Science Daily: Pharmacology News
JANUARY 9, 2025
A new study provides the first comprehensive global estimates of the amount of water stored in Earth's plants and the amount of time it takes for that water to flow through them. The information is a missing piece of the puzzle in understanding the global water cycle and how that cycle is being altered by changes in land use and climate.
Drugs.com
JANUARY 8, 2025
WEDNESDAY, Jan. 8, 2025 -- For many, coffee is a beloved morning ritual, fueling the day ahead. But what if the time you drink it could influence how long -- and how well -- you live?New research published Jan. 8 in the European Heart Journal.
BioPharma Drive: Drug Pricing
JANUARY 6, 2025
The stage is set for JPM 2025—don't miss expert reactions following 2025’s principal catalyst event!
Covalent Modifiers
JANUARY 9, 2025
Matthew Bogyo, Tulsi Upadhyay, Emily Woods, Stephen Ahator. Kjersti Julin, Franco Faucher, Marijn Hollander, Nichole Pedowitz, Daniel Abegg, Isabella Hammond, Ifeanyichukwu Eke, Sijie Wang, Shiyu Chen, John Bennett, Jeyun Jo, Christian Lentz, Alex Adibekian, Matthias Fellner Research Square Preprint 2025 [link] 10.21203/rs.3.rs-5494070/v1 Staphylococcus aureus is a leading cause of bacteria-associated mortality worldwide.
Science Daily: Pharmacology News
JANUARY 7, 2025
A newly described dinosaur whose fossils were recently uncovered is challenging the existing narrative, with evidence that the reptiles were present in the northern hemisphere millions of years earlier than previously known.
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