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Seeds, twigs, and insect parts found under two miles of ice confirm Greenland's ice sheet melted in the recent past, the first direct evidence that the center -- not just the edges -- of the two-mile-deep ice melted away in the recent geological past. The new research indicates that the giant ice sheet is more fragile than scientists had realized until the last few years -- and reveals increased risk of sea-level catastrophe in a warmer future.
The funding from Apple Tree Partners will help the startup advance an antiviral drug pipeline that includes a COVID treatment nearing mid-stage testing.
THURSDAY, Aug. 8, 2024 -- There's more evidence to suggest that the common artificial sweetener erythritol might pose dangers to consumers' hearts.The new study, involving 20 healthy adult volunteers, found that at doses commonly found in an.
Santiago, Chile – August 6, 2024—Merken Biotech, a leading research service company in biotechnology, proudly announces the adoption of CDD Vault, a premier informatics platform by Collaborative Drug Discovery (CDD). This strategic move will enhance Merken Biotech’s service capabilities, streamlining data management and accelerating drug discovery processes for its clients.
Speaker: Simran Kaur, Co-founder & CEO at Tattva.Health
AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!
Scientists have recovered the first long section of rocks that originated in the Earth's mantle, the layer below the crust and the planet's largest component. The rocks will help unravel the mantle's role in the origins of life on Earth, the volcanic activity generated when it melts, and how it drives the global cycles of important elements such as carbon and hydrogen.
Through a new deal, Roche has exclusive rights to Sangamo molecules designed to repress the gene that makes “tau,” a protein many scientists view as a main driver of Alzheimer’s.
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Drug Discovery Digest brings together the best content for drug research and development professionals from the widest variety of industry thought leaders.
Through a new deal, Roche has exclusive rights to Sangamo molecules designed to repress the gene that makes “tau,” a protein many scientists view as a main driver of Alzheimer’s.
FRIDAY, Aug. 9, 2024 -- Pollen is a known trigger for seasonal allergies and asthma, but new research suggests that certain plant species release pollen that are especially tough on asthmatics.Species-specific pollen alerts could help keep people.
Thatikonda, V., Lyu, H., Jurado, S. et al. Nat Cancer (2024). [link] Combination approaches are needed to strengthen and extend the clinical response to KRASG12C inhibitors (KRASG12Ci). Here, we assessed the antitumor responses of KRASG12C mutant lung and colorectal cancer models to combination treatment with a SOS1 inhibitor (SOS1i), BI-3406, plus the KRASG12C inhibitor, adagrasib.
A 'loopy' discovery in bacteria is raising fundamental questions about the makeup of our own genome -- and revealing a potential wellspring of material for new genetic therapies.
Recent data from J.P. Morgan indicates early-stage startups are getting smaller upfront payments in alliances than a few years ago, a trend industry insiders attribute to weaker leverage in deal talks.
Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.
The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven
FRIDAY, Aug. 9, 2024 -- In findings that offer compelling evidence of the power of childhood vaccines, a new government report shows the routine shots have prevented hundreds of millions of illnesses, tens of millions of hospitalizations and more.
Rowan Stringer and Tobias Kaster Journal of Medicinal Chemistry 2024 DOI: 10.1021/acs.jmedchem.4c00776 30 covalent drugs were used to assess clearance (CL) prediction reliability in animals and humans. In animals, marked CL underprediction was observed using cryopreserved hepatocytes or liver microsomes (LMs) supplemented for cytochrome P450 activity.
A new study reports the discovery of extremely rare early human fossils from the Indonesian island of Flores, including an astonishingly small adult limb bone. Dated to about 700,000 years old, the new findings shed light on the evolution of Homo floresiensis, the so-called 'Hobbits' of Flores whose remains were uncovered in 2003 at Liang Bua cave in the island's west.
The decision to turn down an application from Lykos Therapeutics comes at a pivotal time for psychedelics research, which, after decades of dismissal, has recently gained momentum.
Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.
THURSDAY, Aug. 8, 2024 -- Plenty of women know that having an IUD inserted in their uterus can be an excruciating experience, but new government guidance issued Thursday may soon make the experience less painful for many.For the first time, updated.
What are the main therapeutic areas beyond oncology where ADCs show potential? A number of areas represent significant opportunities for Antibody Drug Conjugates (ADCs) beyond oncology, leveraging their ability to deliver therapeutic agents specifically to diseased cells or tissues while minimising off-target effects. The development of ADCs in these areas is ongoing, with several preclinical and clinical studies exploring their potential.
Ever since we learned that the surface of planet Mars is cold and dead, people have wondered if there is a way to make it friendlier to life. The newly proposed method is over 5,000 times more efficient than previous schemes to globally warm Mars, representing a significant leap forward in our ability to modify the Martian environment.
Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.
THURSDAY, Aug. 8, 2024 -- People who use marijuana at high levels are putting themselves at more than three times the risk for head and neck cancers, new research warns.The study is perhaps the most rigorous ever conducted on the issue, tracking.
In today’s rapidly evolving digital landscape, financial services organizations are increasingly relying on cutting-edge technologies to stay competitive and deliver exceptional services to their clients. Microsoft’s Azure Integration Services , a suite of tools designed to seamlessly connect applications, data, and processes, is emerging as a game-changer for the financial services industry.
We are constantly surrounded by electromagnetic waves such as Wi-Fi. Researchers tested a device to convert this ambient energy into energy for electronic devices.
Sales of the in-demand obesity drug crested $1 billion in the second quarter as improved Lilly production helped the company fulfill wholesaler backorders.
Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic
WEDNESDAY, Aug. 7, 2024 (HealthDay news) -- Medicare and Medicaid patients are less likely to get cutting-edge weight-loss drugs than people with private insurance are, a new study finds.Medicaid accounted for less than 10% of semaglutide (Ozempic.
The clinical trials industry is changing rapidly to move with today's technological advancements and at the front of this exciting movement is the adoption of AI (Artificial Intelligence) and ML (Machine Learning). Our industry has successfully incorporated both innovations to help push the boundaries of medical research and increase its effectiveness and efficiency through using these tools to help streamline and automate critical processes, which previously would have taken far longer to compl
Scientists from across academic disciplines are extremely concerned about climate change. Many of them have already changed their own lifestyles or engaged in advocacy and protest, with even more being willing to do so in future. This is evident from a large-scale survey of scientists from all over the world.
After months of supply strains, Lilly has begun to catch up with demand. Consumers may still need to wait for their prescriptions to be filled, however.
MONDAY, Aug. 5, 2024 -- Botanicals like turmeric, green tea and black cohosh may seem benign, but their overuse is being increasingly linked to liver injury. New research suggests that 7% of U.S. adults are using at least one of the six leading.
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