Sat.Dec 28, 2024 - Fri.Jan 03, 2025

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How do GLP-1s Boost Weight Loss, Heart Health?

Drugs.com

THURSDAY, Jan. 2, 2024 -- Weight loss tops many folks list of New Years resolutions, and lots of people are turning to cutting-edge weight-loss drugs like Ozempic to help them drop excess pounds.These drugs, called glucagon-like peptide-1 receptor.

Drugs 290
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Zebrafish protein unlocks dormant genes for heart repair

Science Daily: Pharmacology News

Researchers have successfully repaired damaged mouse hearts using a protein from zebrafish. They discovered that the protein Hmga1 plays a key role in heart regeneration in zebrafish. In mice, this protein was able to restore the heart by activating dormant repair genes without causing side effects, such as heart enlargement. This study marks an important step toward regenerative therapies to prevent heart failure.

Therapies 308
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Chemoselective Stabilized Triphenylphosphonium Probes for Capturing Reactive Carbonyl Species and Regenerating Covalent Inhibitors with Acrylamide Warheads in Cellulo

Covalent Modifiers

Ai-Lin Chen, Zih-Jheng Lin, Hsiao-Yu Chang, and Tsung-Shing Andrew Wang Journal of the American Chemical Society , 2025 [link] Reactive carbonyl species (RCS) are important biomarkers of oxidative stress-related diseases because of their highly reactive electrophilic nature. Despite their potential as triggers for prodrug activation, selective labeling approaches for RCS remain limited.

Disease 182
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10 clinical trials to watch in the first half of 2025

BioPharma Drive: Drug Pricing

Expected readouts in diabetes, cancer and depression headline a series of study results that could help the biotechnology sector regain its footing after a shaky year.

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Bridging Innovation & Patient Care: The Growing Role of AI

Speaker: Simran Kaur, Co-founder & CEO at Tattva.Health

AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!

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Norovirus Cases Are Up in Pockets of the U.S.

Drugs.com

MONDAY, Dec. 30, 2024 -- Norovirus, a highly contagious stomach bug, is surging across the United States this winter, according to the latest data from the U.S. Centers for Disease Control and Prevention (CDC).The data shows 91 outbreaks of.

Disease 290

More Trending

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Natural Intelligence?

Molecular Design

My pulse will be quickenin' With each drop of strychnine We feed to a pigeon It just takes a smidgin To poison a pigeon in the park Tom Lehrer, Poisoning Pigeons in the Park | video ** Ill be reviewing the H2024 study (Occurrence of Natural Selection in Successful Small Molecule Drug Discovery) in this post. Derek has already posted on the H2024 study which been included in the BL2024 Virtual Special Issue on natural products (NPs) in medicinal chemistry.

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Neumora plummets on depression drug data

BioPharma Drive: Drug Pricing

The well-funded biotech lost most of its value after its drug flunked a late-stage trial. One analyst described the results as a “worst-case scenario for the program.

Drugs 171
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Ready-to-Eat Broccoli Pulled from Walmart Shelves Due to Listeria Risk

Drugs.com

FRIDAY, Jan. 3, 2025 -- If you've picked up a bag of Marketside Broccoli Florets from Walmart recently, check your fridge or freezer. The company has issued a recall of the 12-ounce bags in 20 states after testing uncovered listeria bacteria in one.

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New method turns e-waste to gold

Science Daily: Pharmacology News

A research team has developed a method for extracting gold from electronics waste, then using the recovered precious metal as a catalyst for converting carbon dioxide (CO2), a greenhouse gas, to organic materials.

Research 348
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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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CDD Vault 2024 in Review: Celebrating 20 Years of Innovation

Collaborative Drug

2024 was a special year as we celebrated two decades of CDD Vault.

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FDA approves drugs from Vertex, Novo, Bristol Myers to wrap 2024

BioPharma Drive: Drug Pricing

The agency’s main drug review office cleared 50 novel medicines last year, short of 2018’s record total but on the higher end of recent annual tallies.

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Fast, Easy Nasal Swab Helps Diagnose Asthma Type in Kids

Drugs.com

THURSDAY, Jan. 2, 2024 -- Not sure what’s causing your child’s asthma? A new quick-and-easy nasal swab test for kids can diagnose the specific immune system drivers behind their asthma, potentially opening the door to better treatments.

Treatment 277
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The carbon in our bodies probably left the galaxy and came back on cosmic 'conveyer belt'

Science Daily: Pharmacology News

Scientists recently discovered that the giant 'conveyer belt' currents that push star-forged material out of our galaxy and pull it back in can also transport carbon atoms. That means that a good deal of the carbon here on Earth, including the carbon in our bodies, likely left the galaxy at some point!

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How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

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Understanding the Regulatory Environment in Japan for Generic Drug Development

Drug Patent Watch

The regulatory environment in Japan for generic drug development is complex and has undergone significant changes in recent years. This article aims to provide a comprehensive overview of the key aspects of the regulatory framework, highlighting the requirements and challenges faced by pharmaceutical companies seeking to introduce generic drugs into the Japanese market.

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Pfizer exits Sangamo pact; Roche, Ideaya strike ADC deals

BioPharma Drive: Drug Pricing

Sangamo shares fell on Pfizer’s decision to hand back rights to a hemophilia gene therapy. Elsewhere, Novartis got long-awaited data and BioNTech settled with the NIH.

Therapies 148
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Every Cigarette Smoked Could Cost You 22 Minutes of Life, Research Says

Drugs.com

THURSDAY, Jan. 2, 2025 -- Considering a New Year’s resolution to quit smoking? New research might provide all the motivation you need: Each cigarette could shorten your life by up to 22 minutes, researchers say. The findings, published Dec.

Research 264
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Loneliness linked to higher risk of heart disease and stroke and susceptibility to infection

Science Daily: Pharmacology News

Interactions with friends and family may keep us healthy because they boost our immune system and reduce our risk of diseases such as heart disease, stroke and type 2 diabetes, new research suggests. Researchers drew this conclusion after studying proteins from blood samples taken from over 42,000 adults recruited to the UK Biobank.

Disease 339
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Deliver Fast, Flexible Clinical Trial Insights with Spotfire

Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

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Chemical Biology and Drug Design

Cover Image molekuul_be/Shutterstock.

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A new roadmap for cannabis and cannabis policy research

National Institute on Drug Abuse: Nora's Blog

A new roadmap for cannabis and cannabis policy research mfleming Fri, 01/03/2025 - 11:38 Nora's Blog January 14, 2025 Image Getty Images/ Fiordaliso The greatly increased availability of cannabis over the last two decades has outpaced our understanding of the public-health impacts of the drug. It is now available for medical purposes in most states, and adults may now purchase it for recreational use in nearly half the states.

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Experts Warn of Growing Risks as Bird Flu Cases Rise

Drugs.com

THURSDAY, Jan. 2, 2025 -- A Canadian teen's severe bird flu infection has highlighted growing concerns about the H5N1 virus, commonly known as bird flu, which has seen a steady rise in human cases across the U.S. According to a news release, the.

Virus 264
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Ancient DNA unlocks new understanding of migrations in the first millennium AD

Science Daily: Pharmacology News

Waves of human migration across Europe during the first millennium AD have been revealed using a more precise method of analysing ancestry with ancient DNA, in research led by the Francis Crick Institute.

DNA 339
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Clinical Data Like You´ve Never Seen It Before: Why Spotfire Is the Leading Tool for Clinical Analytics

Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

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Innovation in container closer systems and aseptic processing for ATMPs

Fierce BioTech

Innovation in container closer systems and aseptic processing for ATMPs dwunderlin Fri, 01/03/2025 - 14:26 Wed, 02/12/2025 - 10:00 Resource Type Webinar Jim Thompson Julian Petersen Duration 60 Minutes The pharmaceutical landscape is shifting from blockbuster drugs to personalized treatments, driving the need for innovative container closure systems.

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The Twelve Days of Antibodies

addgene Blog

Every year, we like to add in some holiday cheer to our blog and social media. This year, we're doing so through the twelve days of antibodies. We hope you enjoy it, and we wish you a great 2025!

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New Legislation Will Help Schools Handle Heart Emergencies

Drugs.com

SATURDAY, Dec. 27, 2024 -- Schoolkids will be better able to save the life of a cardiac arrest victim, thanks to a new law signed this week by President Joe Biden.The Cardiomyopathy Health Education, Awareness, Research and Training in Schools.

Research 263
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Breakthrough for 'smart cell' design

Science Daily: Pharmacology News

Bioengineers have developed a new construction kit for building custom sense-and-respond circuits in human cells. The research could revolutionize therapies for complex conditions like autoimmune disease and cancer.

Therapies 337
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Optimizing Formulation Strategies for Poorly Soluble Compounds: Insights into Bioavailability Enhancement and Accelerated Development

Fierce BioTech

Optimizing Formulation Strategies for Poorly Soluble Compounds: Insights into Bioavailability Enhancement and Accelerated Development dwunderlin Fri, 01/03/2025 - 15:54 Wed, 02/19/2025 - 11:00 Resource Type Webinar Feng Zhang, Ph.D. Hong Li, Ph.D. Duration 60 Minutes With 70% of small molecule drug candidates classified as poorly soluble (BCS Class II and IV), achieving adequate absorption in the gastrointestinal (GI) tract remains a critical challenge in drug development.