Sat.Jul 01, 2023 - Fri.Jul 07, 2023

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The Growing Role of CROs in Clinical Trials

PPD

It’s estimated that nearly three out of every four clinical trials are conducted by contract research organizations (CROs), highlighting just how much sponsors value — and rely on — the work that CROs perform. As clinical trials become more complex, sponsors are seeking business partnerships with a congruency in the management and prioritization of pipeline.

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FDA Approves First Blood Test to Predict Preeclampsia in Pregnant Women

Drugs.com

WEDNESDAY, July 5, 2023 -- A new blood test approved by the U.S. Food and Drug Administration can predict imminent preeclampsia, helping pregnant women who are at risk for this severe and sometimes deadly form of high blood pressure. The test can.

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Pfizer backs CRISPR biotech Caribou in latest cell therapy investment

BioPharma Drive: Drug Pricing

Five years after helping launch Allogene Therapeutics, Pfizer is backing another developer of “off-the-shelf” cell therapies in a deal that gives the drugmaker the chance to acquire a multiple myeloma treatment.

Therapies 327
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Similar to humans, elephants also vary what they eat for dinner every night

Science Daily: Pharmacology News

A detailed analysis of the dietary habits of elephants showed surprising variation from meal to meal, which could have important ramifications for wildlife protection and conservation strategies.

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Bridging Innovation & Patient Care: The Growing Role of AI

Speaker: Simran Kaur, Co-founder & CEO at Tattva.Health

AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!

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Dutch PanCoroNed and its successor coronavirus Consortium select CDD Vault to manage their research data

Collaborative Drug

Dutch PanCoroNed and its successor coronavirus Consortium select CDD Vault to manage their research data.

Research 238

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FDA grants Eisai’s Leqembi full approval, opening door to wider use of Alzheimer’s drug

BioPharma Drive: Drug Pricing

The broader approval is expected to push insurers, namely Medicare, to increase coverage of so-called amyloid-targeting therapies.

FDA 273
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Potent greenhouse gas produced by industry could be readily abated with existing technologies

Science Daily: Pharmacology News

Researchers have found that one method of reducing greenhouse gas emissions is available, affordable, and capable of being implemented right now. Nitrous oxide, a potent greenhouse gas and ozone-depleting substance, could be readily abated with existing technology applied to industrial sources.

Research 259
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Antibody Drug Conjugates: windows of opportunity

Drug Target Review

Over the last two decades, an increasing number of Antibody Drug Conjugate (ADC) therapeutics have been approved for oncology indications. These therapies have broadened treatment options for patients to expand beyond the more traditional small molecule drug alternatives. Through their unique modes of action, ADCs have been heralded as having the potential to positively impact not only cancer patient outcomes but also quality of life, an increasingly important factor in treatment decisions for t

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Learn the Differences Between Hepatitis A, B, C, D & E

Drugs.com

THURSDAY, July 6, 2023 -- Curious about what the differences are between hepatitis A, B, C, D and E? If so, you’ve come to the right place. Here, experts break down hepatitis infection by type to reveal what it is, the most common symptoms, how.

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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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With new data, J&J steps forward in growing race for oral autoimmune drugs

BioPharma Drive: Drug Pricing

Phase 2 results show a pill the company is developing is competitive with other oral medicines in testing against psoriasis, among them the TYK2 inhibitors that have drawn significant industry interest.

Drugs 273
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Triple combination therapy brings lasting improvement in cystic fibrosis

Science Daily: Pharmacology News

The mucus in the airways is not as sticky, inflammation in the lungs significantly reduced: Triple combination therapy can achieve these positive, lasting effects in patients with cystic fibrosis (CF). According to new research, this form of medication improves the symptoms of CF in many patients.

Therapies 255
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Expanding the Chemistry of Dihaloacetamides as Tunable Electrophiles for Reversible Covalent Targeting of Cysteines

Covalent Modifiers

Daiki Yamane, Ryo Tetsukawa, Naoki Zenmyo, Kaori Tabata, Yuya Yoshida, Naoya Matsunaga, Naoya Shindo, and Akio Ojida Journal of Medicinal Chemistry 2023 DOI: 10.1021/acs.jmedchem.3c00737 The choice of an appropriate electrophile is crucial in the design of targeted covalent inhibitors (TCIs). In this report, we systematically investigated the glutathione (GSH) reactivity of various haloacetamides and the aqueous stability of their thiol adducts.

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Hepatitis C Treatments: A Comprehensive Guide

Drugs.com

THURSDAY, July 6, 2023 -- Did you know the U.S. Centers for Disease Control and Prevention estimates that there were nearly 68,000 new cases of acute hepatitis C in 2020 and over 107,000 newly reported cases of chronic hepatitis C? To help you.

Treatment 299
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How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

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Sarepta sells FDA fast pass earned from Duchenne gene therapy approval

BioPharma Drive: Drug Pricing

The deal enables Sarepta to quickly cash in on the clearance of Elevidys, with $102 million in new funds to help bankroll its drug research.

Therapies 262
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Global diet study challenges advice to limit high-fat dairy foods

Science Daily: Pharmacology News

Unprocessed red meat and whole grains can be included or left out of a healthy diet, according to a study conducted in 80 countries across all inhabited continents. Diets emphasizing fruit, vegetables, dairy (mainly whole-fat), nuts, legumes and fish were linked with a lower risk of cardiovascular disease (CVD) and premature death in all world regions.

Disease 243
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Connect In Pharma 2023 Revealed Latest Trends in Pharmaceutical Manufacturing and Drug Delivery

Drug Discovery Today

London, UK, 28 June 2023 / Sciad Newswire / Hosting leading industry experts from across Europe, Connect in Pharma 2023 revealed future trends in pharma and AI, sustainability, and preventative medicine during a two-day meeting in Geneva on 14 & 15 June.

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Australian Footballer Is First Female Athlete to Receive Diagnosis of CTE

Drugs.com

WEDNESDAY, July 5, 2023 -- Heather Anderson, a star Australian rules football player who died last November, is the first female professional athlete to be diagnosed with chronic traumatic encephalopathy, or CTE. "She is the first female athlete.

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Deliver Fast, Flexible Clinical Trial Insights with Spotfire

Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

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What US trial sponsors should know about the GDPR

BioPharma Drive: Drug Pricing

What is the GDPR and why does it matter to your life sciences company. iliomad Health Data can help you maintain GDPR compliance.

Trials 246
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Not eating enough of these six healthy foods is associated with higher cardiovascular disease and deaths globally

Science Daily: Pharmacology News

Previous and similar research has focused on Western countries and diets that combined harmful, ultra-processed foods with nutrient-dense foods. This research was global in scope and focused on foods commonly considered to be healthy. Researchers derived a diet score from PHRI's ongoing, large-scale global Prospective Urban and Rural Epidemiological (PURE) study, then replicated that in five independent studies to measure health outcomes in different world regions and in people with and without

Disease 224
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Register now to visit Lab Innovations 2023

Drug Discovery Today

Secure your ticket for the UK’s largest trade show for the whole lab industry

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New Heart Implant Monitors, Treats -- and Then Dissolves Away

Drugs.com

FRIDAY, July 7, 2023 -- An experimental implant now under development could serve as a temporary monitor and pacemaker for ailing heart patients -- then dissolve away when it’s no longer needed. The soft, lightweight and transparent implant.

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Clinical Data Like You´ve Never Seen It Before: Why Spotfire Is the Leading Tool for Clinical Analytics

Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

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Moderna, chasing GSK and Pfizer, brings RSV vaccine to regulators

BioPharma Drive: Drug Pricing

The vaccine has a chance to become Moderna’s second approved product and could help offset declining sales for its COVID-19 shot.

Vaccine 171
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Eliminating extra chromosomes in cancer cells prevent tumor growth

Science Daily: Pharmacology News

Cancer cells with extra chromosomes depend on those chromosomes for tumor growth, a new study reveals, and eliminating them prevents the cells from forming tumors. The findings, said the researchers, suggest that selectively targeting extra chromosomes may offer a new route for treating cancer.

Research 219
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Exploring alternatives to animal testing in drug discovery

Drug Target Review

Animal testing plays a significant role in pre-clinical research and therefore requires the use of millions of animals. In Britain, 2.88 million scientific procedures involving live animals were carried out in 2020. 1 Over a quarter of those were for basic research purposes, with most common areas focused on the immune system, the nervous system and oncology. 1 Ethical concerns surrounding the use of animal studies is increasing, especially considering 90 percent of drug candidates fail in clini

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Another Enemy on the Front Lines in Ukraine: Antibiotic-Resistant Germs

Drugs.com

TUESDAY, July 4, 2023 -- Bacteria found in hospital patients in Ukraine is showing extreme antibiotic resistance, making it harder to treat the wounded and ill in this war-torn country, new research warns. “I am quite thick-skinned and have.

Hospitals 299
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Brii buys further into VBI therapy, expanding hepatitis B partnership

BioPharma Drive: Drug Pricing

The deal comes three months after VBI cut costs and laid off staff in a restructuring meant to prioritize the two medicines Brii is interested in.

Therapies 164