Sat.Mar 02, 2024 - Fri.Mar 08, 2024

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FDA Warns of Toxic Lead in Cinnamon Products

Drugs.com

WEDNESDAY, March 6, 2024 -- The U.S. Food and Drug Administration issued a health advisory Wednesday warning consumers that six brands of ground cinnamon are tainted with lead. The FDA urged folks to throw away and not buy the following brands of.

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A smart molecule beats the mutation behind most pancreatic cancer

Science Daily: Pharmacology News

Researchers have designed a candidate drug that could help make pancreatic cancer, which is almost always fatal, a treatable, perhaps even curable, condition.

Research 352
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Amylyx ALS drug fails crucial study, putting company’s future in doubt

BioPharma Drive: Drug Pricing

The results have led Amylyx to pause promotion of Relyvrio and potentially pull it from the market in the coming weeks, a major blow to the company and ALS patients.

Marketing 339
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Early Impact Of The Inflation Reduction Act On Drug Discovery

Forbes: Drug Truths

There is another aspect of this provision of the IRA that is starting to be felt – "the small molecule penalty"

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Bridging Innovation & Patient Care: The Growing Role of AI

Speaker: Simran Kaur, Co-founder & CEO at Tattva.Health

AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!

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Carcinogen Benzene Can Form in Some Acne Treatments: Report

Drugs.com

THURSDAY, March 7, 2024 -- Some acne treatments may may banish blemishes but carry hidden dangers: A new report reveals high levels of the carcinogen benzene can form in products that contain the zit-fighting ingredient benzoyl peroxide.According.

Treatment 306

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Boundless Bio, a Bayer-backed cancer biotech, seeks an IPO

BioPharma Drive: Drug Pricing

The startup, which has raised nearly $254 million privately, is in early testing with drugs designed to target particularly tough-to-treat tumors.

Drugs 294
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Does Federally Funded Research Justify A Piece Of Pharma’s Profits?

Forbes: Drug Truths

The thought that all drugs arise from government funded research is a fallacy.

Research 222
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Co-founder of Company Behind Deadly 2012 Meningitis Outbreak Gets Up to 15 Years in Prison

Drugs.com

WEDNESDAY, March 6, 2024 -- Barry Cadden, co-founder of a specialty compounding pharmacy behind a deadly meningitis outbreak in 2012, has been handed a prison sentence of 10 to 15 years in Michigan for involuntary manslaughter.On Tuesday, Cadden.

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Using light to precisely control single-molecule devices

Science Daily: Pharmacology News

Researchers flip the switch at the nanoscale by applying light to induce bonding for single-molecule device switching.

Research 329
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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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FDA delays decision on Lilly’s closely watched Alzheimer’s drug

BioPharma Drive: Drug Pricing

The agency expects to convene a group of outside experts to more closely scrutinize the safety and efficacy of the medicine, donanemab, pushing back the timing of its potential approval.

FDA 292
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Strain-release alkylation of Asp12 enables mutant selective targeting of K-Ras-G12D

Covalent Modifiers

Qinheng Zheng, Ziyang Zhang, Keelan Z. Guiley & Kevan M. Shokat Nat Chem Biol 2024 [link] K-Ras is the most commonly mutated oncogene in human cancer. The recently approved non-small cell lung cancer drugs sotorasib and adagrasib covalently capture an acquired cysteine in K-Ras-G12C mutation and lock it in a signaling-incompetent state. However, covalent inhibition of G12D, the most frequent K-Ras mutation particularly prevalent in pancreatic ductal adenocarcinoma, has remained elusive due t

Drugs 182
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FDA Approves Wegovy to Help Prevent Heart Attack, Stroke

Drugs.com

FRIDAY, March 8, 2024 -- Wegovy (semaglutide), the weight-loss version of blockbuster diabetes drug Ozempic, was approved on Friday by the U.S. Food and Drug Administration to help prevent heart attack, stroke and heart death.“Wegovy is now the.

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Fossils of giant sea lizard with dagger-like teeth show how our oceans have fundamentally changed since the dinosaur era

Science Daily: Pharmacology News

Fossils of a strange new species of marine lizard with dagger-like teeth that lived 66 million years ago, show a dramatically more biodiverse ocean ecosystem to what we see today.

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How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

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Novo’s latest obesity pill spurs major weight loss in small trial

BioPharma Drive: Drug Pricing

Early results from a Phase 1 study suggest the drug, amycretin, could be as potent as injectable medicines already sold by Novo and rival Eli Lilly.

Trials 287
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Recorded Webinar: CDD at "Best of the Best Entity Registration Mega Webinar"

Collaborative Drug

Recorded Webinar: CDD at 'Best of the Best Entity Registration Mega Webinar'

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Wegovy, Ozempic Use Could Complicate Your Surgery

Drugs.com

WEDNESDAY, March 6, 2024 -- Weight-loss drugs like Wegovy and Ozempic can increase a person’s risk of throwing up during surgery while under anesthesia, a new study reports. People are typically asked to fast prior to surgery because general.

Drugs 290
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Lack of focus doesn't equal lack of intelligence -- it's proof of an intricate brain

Science Daily: Pharmacology News

Imagine a busy restaurant: dishes clattering, music playing, people talking loudly over one another. It's a wonder that anyone in that kind of environment can focus enough to have a conversation. A new study provides some of the most detailed insights yet into the brain mechanisms that help people pay attention amid such distraction, as well as what's happening when they can't focus.

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Deliver Fast, Flexible Clinical Trial Insights with Spotfire

Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

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Alnylam, Roche blood pressure drug scores in second mid-stage trial

BioPharma Drive: Drug Pricing

The study results further validate Roche’s recent decision to acquire rights to the drug, which is being developed for people with a stubborn form of hypertension.

Trials 287
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Schizophrenia and aging may share a common biological basis

Broad Institute

Schizophrenia and aging may share a common biological basis By Allessandra DiCorato March 6, 2024 Breadcrumb Home Schizophrenia and aging may share a common biological basis Tightly synchronized genetic changes in two types of brain cells may underlie cognitive impairment in both conditions, offering potential therapeutic clues. By Allessandra DiCorato March 6, 2024 Credit: Ricardo Job-Reese, Broad Communications A new study of aging and schizophrenia reveals synchronized gene expression in astr

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U.S. School Shootings Have Risen 12-fold Since 1970

Drugs.com

FRIDAY, March 8, 2024 -- During the past half-century, the United States’ annual number of school shootings has increased more than twelvefold, a new study finds.What’s more, children are now four times more likely to be a school shooting.

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Sinking land increases risk for thousands of coastal residents by 2050

Science Daily: Pharmacology News

A new study provides a new comprehensive look at the potential for flooding in a combined 32 cities along the Atlantic, Pacific, and Gulf coasts. It predicts as many as 500,000 people will be affected by flooding alongside 1 in 35 privately owned properties within the next three decades, and it highlights the racial and socioeconomic demographics of those potentially affected.

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Clinical Data Like You´ve Never Seen It Before: Why Spotfire Is the Leading Tool for Clinical Analytics

Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

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NodThera says inflammation drug has positive effect in Parkinson’s

BioPharma Drive: Drug Pricing

The results from the privately held biotech add to early evidence supporting the potential of an increasingly popular drug target known as NLRP3 inflammasomes.

Drugs 280
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Study reveals genetic clusters that may explain differences in type 2 diabetes risk

Broad Institute

Study reveals genetic clusters that may explain differences in type 2 diabetes risk By Corie Lok March 8, 2024 Breadcrumb Home Study reveals genetic clusters that may explain differences in type 2 diabetes risk The clusters point to a range of biological processes that likely contribute to the development of type 2 diabetes. By Brandon Chase, Massachusetts General Hospital Communications March 8, 2024 Related content Largest and most diverse genome-wide association study of type 2 diabetes revea

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FDA Clears First OTC Continuous Blood Glucose Monitor

Drugs.com

WEDNESDAY, March 6, 2024 -- The U.S. Food and Drug Administration on Tuesday approved the country's first continuous glucose monitor for type 2 diabetes.The new Dexcom Stelo Glucose Biosensor System, which will be available by summer, is intended.

FDA 278
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Orcas demonstrating they no longer need to hunt in packs to take down the great white shark

Science Daily: Pharmacology News

An orca (killer whale) has been observed, for the first-ever time, individually consuming a great white shark -- and within just two minutes.

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Bayer pays $310M to buy into BridgeBio heart drug

BioPharma Drive: Drug Pricing

The deal gives the German pharma partial rights to a closely watched medicine for transthyretin amyloidosis cardiomyopathy that analysts expect to become a multibillion-dollar product.