Sat.Jun 24, 2023 - Fri.Jun 30, 2023

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Biopharma Facing Two Major Crises - A Huge Patent Cliff And Price Controls

Forbes: Drug Truths

Out of necessity, the industry will have to make significant cuts to its R&D operations. Research sites will be cut back or eliminated, therapeutic areas will be dropped and jobs will be lost.

Research 196
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BioMarin finally secures FDA approval of hemophilia gene therapy

BioPharma Drive: Drug Pricing

After a prolonged journey, the medicine, known as Roctavian, is now cleared for certain patients with hemophilia A, the more common form of the rare bleeding disorder.

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Don't Get (Sun)Burned This 4th of July Weekend

Drugs.com

FRIDAY, June 30, 2023 -- Adding sun protection to your holiday gatherings takes little effort and can help you avoid the pain and potential side effects of sunburn. As Americans prepare to celebrate July 4 with parades, swimming and cookouts, the.

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New study sheds light on the evolution of animals

Science Daily: Pharmacology News

Scientists have been mystified as to why animals are missing in much of the fossil record. Researchers have now developed a new method to determine if animals really were absent during certain geological eras, or if they were present but too fragile to be preserved.

Research 278
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Bridging Innovation & Patient Care: The Growing Role of AI

Speaker: Simran Kaur, Co-founder & CEO at Tattva.Health

AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!

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Recorded Webinar: Artificial Intelligence Drug Discovery - Where are we now?

Collaborative Drug

Recorded Webinar: Artificial Intelligence Drug Discovery - Where are we now?

Drugs 264

More Trending

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Fixing a Painful Joint Problem Won't Ease Mental Health Ills, Study Finds

Drugs.com

FRIDAY, June 30, 2023 -- Blaming your ailing knees for feeling down? Unfortunately, even after physical pain eases, healing or fixing an injured joint often does not improve mental health, research shows. A new study found that anxiety symptoms only.

Research 297
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Gullies on Mars could have been formed by recent periods of liquid meltwater, study suggests

Science Daily: Pharmacology News

A study offers new insights into how water from melting ice could have played a recent role in the formation of ravine-like channels that cut down the sides of impact craters on Mars.

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Drug Discovery Industry Roundup with Barry Bunin — June 26, 2023

Collaborative Drug

Drug Discovery Industry Roundup with Barry Bunin — June 26, 2023

Drugs 236
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5 FDA decisions to watch in the third quarter

BioPharma Drive: Drug Pricing

By the end of September, the FDA will hold two anticipated advisory meetings and issue important decisions on drugs for Alzheimer’s, depression and a type of vision loss.

FDA 273
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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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CDC Gives Full Approval to RSV Shots, Arexvy and Abrysvo, for People Over 60; Vaccines Available This Fall

Drugs.com

THURSDAY, June 29, 2023 -- Americans ages 60 and up can get their vaccine for respiratory syncytial virus (RSV) this fall, the U.S. Centers for Disease Control and Prevention announced Thursday. On Thursday, Dr. Rochelle Walensky, the outgoing CDC.

Vaccine 290
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Virus-like transposons wage war on the species barrier

Science Daily: Pharmacology News

Scientists have known for decades that genes can be transferred from one species to another, both in animals and plants. However, the mechanism of how such an unlikely event occurs remained unknown. Now, researchers identify a vector of horizontal gene transfer (HGT) in worms. The findings could lead to the discovery of further vectors of HGT in eukaryotes and might find applications in pathogen control.

Virus 268
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Recent Highlights in Targeted Protein Degradation

Drug Hunter

In Wednesday’s Flash Talk webinar , we covered recent highlights in targeted protein degradation, with lots of great questions from the audience. The webinar and recording are available below to everyone thanks to our sponsor, Revvity Signals, and the slides are available for download to Premium members at the bottom. The talk covered: Theoretical advantages of targeted protein degradation over traditional small molecules Recent highlights throughout the industry illustrating these advanta

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Pfizer’s hemophilia B gene therapy inches closer to regulatory approval

BioPharma Drive: Drug Pricing

The treatment could become Pfizer’s first marketed gene therapy, an area the pharma has poured significant resources into in recent years.

Therapies 265
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How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

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PrEP Implant That Protects Against HIV Could Be Near

Drugs.com

THURSDAY, June 29, 2023 -- Animal research is pointing toward a new way to prevent HIV infection: a refillable implant that continuously delivers antiretroviral medications for up to 20 months at a time.

Research 279
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Mountains vulnerable to extreme rain from climate change

Science Daily: Pharmacology News

A new study finds that as rising global temperatures shift snow to rain, mountains across the Northern Hemisphere will be hotspots for extreme rainfall events that could trigger floods and landslides -- potentially impacting a quarter of the world's population.

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Researchers uncover new CRISPR-like system in animals that can edit the human genome

Broad Institute

Researchers uncover new CRISPR-like system in animals that can edit the human genome By Leah Eisenstadt June 28, 2023 Breadcrumb Home Researchers uncover new CRISPR-like system in animals that can edit the human genome The first RNA-guided DNA-cutting enzyme found in eukaryotes, Fanzor could one day be harnessed to edit DNA more precisely than CRISPR/Cas systems.

RNA 139
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F-Prime’s Ketan Patel on ‘reverse ageism’ in biotech and investing in a downturn

BioPharma Drive: Drug Pricing

The life sciences investor spoke with BioPharma Dive about emerging life sciences markets around the globe and why the firm invests in first-time biotech founders.

Science 264
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Deliver Fast, Flexible Clinical Trial Insights with Spotfire

Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

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Kids Who Read for Pleasure Grow Into Better-Adjusted Teens: Study

Drugs.com

WEDNESDAY, June 28, 2023 -- Young children may be fascinated by electronic devices, but a new study suggests that old-fashioned reading may help them grow into better adjusted middle schoolers. The study, of more than 10,000 U.S. "tweens," found.

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Humans' ancestors survived the asteroid impact that killed the dinosaurs

Science Daily: Pharmacology News

A Cretaceous origin for placental mammals, the group that includes humans, dogs and bats, has been revealed by in-depth analysis of the fossil record, showing they co-existed with dinosaurs for a short time before the dinosaurs went extinct.

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Molecules on the Move: Reversible BTKi in MS, THR-beta Agonist in NASH, and More

Drug Hunter

This article compiles recent high-profile clinical readouts and related news with small molecules of general interest and structures where they are available. Targets and indications discussed in this article include BTK for MS, Axl, TYRO3, and Mer for oncology, HIF prolyl-hydroxylase in anemia, ET/AT in nephrology, a JAK2 inhibitor for myelofibrosis, and THR-beta in NASH.

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With FDA approval in hand, BioMarin lays out plan to sell $2.9M gene therapy

BioPharma Drive: Drug Pricing

The agency granted a long-awaited clearance on Thursday, but unexpected aspects of the hemophilia treatment’s label had some investors worried about its commercial prospects.

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Clinical Data Like You´ve Never Seen It Before: Why Spotfire Is the Leading Tool for Clinical Analytics

Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

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Forty Percent of U.S. Girls, Young Women Are Iron Deficient

Drugs.com

WEDNESDAY, June 28, 2023 -- Nearly 4 out of 10 girls and young women aren’t getting enough iron and they may have their periods to blame, a new U.S. study shows. Menstrual bleeding, especially when heavy, is a major risk factor for iron.

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Significant decline of snow cover in the Northern hemisphere over the last half century

Science Daily: Pharmacology News

A new study that uses rigorous mathematical models and statistical methods and finds declining snow cover in many parts of the northern hemisphere over the last half century.

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Patent Highlights: Allosteric AR Modulators, Glycogen Synthase Inhibitors, and More

Drug Hunter

This article highlights million-dollar molecules that were recently in the news with related patent applications that give clues to their structures and properties. This edition includes Maze’s glycogen synthase 1 (GYS1) inhibitors that were recently licensed to Sanofi, allosteric androgen receptor (AR) modulators that may be of interest to targeted protein degradation researchers, and brain-penetrant HER2 and ROCK2 inhibitors.

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Lilly takes over partner working on cell therapies for diabetes

BioPharma Drive: Drug Pricing

Sigilon Therapeutics, a biotech that’s been collaborating with Lilly since 2018, has agreed to be bought for up to $310 million in the pharma’s second announced buyout this month.

Therapies 247
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Sarah Ferguson Reveals Breast Cancer Diagnosis, Mastectomy

Drugs.com

MONDAY, June 26, 2023 -- Sarah Ferguson has undergone treatment for breast cancer, she announced on her podcast. The Duchess of York, 63, had a mastectomy after the diagnosis and the surgery was successful, her rep confirmed Sunday, People magazine.

Treatment 278