Sat.Jul 22, 2023 - Fri.Jul 28, 2023

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Discover How Louise Kraus Paves the Way For Success

Perficient: Drug Development

At Perficient, we are proud to work with incredible people who give their time and talent to support our clients and communities. Through our People Promise , we strive to challenge, champion, and celebrate the difference that our colleagues are making. For Louise Kraus, a business coordinator based in New Jersey, each day offers the chance to discover new concepts and continue growing as a leader.

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AstraZeneca buys Pfizer’s early gene therapy work for up to $1B

BioPharma Drive: Drug Pricing

The British pharma is deepening its investment in genetic medicine through a deal for a group of Pfizer’s gene therapy delivery tools, while the New York giant cuts back.

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Pharmacovigilance (PV) Services at a Glance

ProRelix Research

Ensuring the safety and efficacy of new drugs, medical devices, and biological products does not end once the treatment is approved or is on the market but extends to the […] The post Pharmacovigilance (PV) Services at a Glance appeared first on ProRelix Research.

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What types of clinical research are there?

Antidote

Before any new therapy can be put on the market, it must be tested to ensure its safety and effectiveness, and the research for this process is done through clinical trials. Clinical trials evaluate new drugs, devices, packaging, and behaviors in order to determine if these potential therapies work for particular conditions or patient populations.

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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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Eclectic Genomics: Cat Flu, Dolphin Adaptation to Climate Change, Predicting Cancer, and Diagnosing Rare Disease

PLOS: DNA Science

Determining the sequence of building blocks of entire genomes – aka genomics – first came to public attention in the 1990s, with the race to decode the first human genomes. Today, smartphones can carry our personal genome sequences. Genomics applies to all species, revealing evolution in action, because we all use the same genetic code – that is, the correspondence between DNA sequences and the amino acid sequences of proteins.

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GSK confident in RSV vaccine launch, but sets expectations for ‘steady build’

BioPharma Drive: Drug Pricing

GSK expects its respiratory syncytial virus vaccine will be a multibillion dollar product. But at the beginning it’s predicting a slower launch than for its fast-selling shingles shot.

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More Trending

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Daily Baby Aspirin Raises Odds for Brain Bleeds, With No Lowering of Stroke Risk

Drugs.com

THURSDAY, July 27, 2023 -- For years, older adults took a baby aspirin a day to help ward off a first-time heart attack or stroke. Now yet another study is showing the risks are not worth it for most. Specifically, researchers found the risk of.

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Optimizely Blocks As Properties: How To Hide Irrelevant Fields

Perficient: Drug Development

We recently ran into an issue when using shared blocks as properties on pages; some of the block’s properties don’t make any sense in this context and can lead to some confusion with editors. Instead of creating another version of the block to use specifically as a local block, I created a simple feature to control hiding properties when a block is used as a property.

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Gilead drug acquired in $5B buyout fails key blood cancer trial

BioPharma Drive: Drug Pricing

Treatment with magrolimab proved ineffective in a Phase 3 study in myelodysplastic syndrome, adding to doubts about so-called CD47 inhibitors as well as Gilead’s deal strategy.

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#ScienceSaturday: July 22, 2023

KIF1A

#ScienceSaturday posts share exciting scientific developments and educational resources with the KAND community. Each week, Dr. Dylan Verden of KIF1A.ORG summarizes newly published KIF1A-related research and highlights progress in rare disease research and therapeutic development. KIF1A-Related Research A Plant Flavonol Rescues a Pathogenic Mutation Associated with Kinesin in Neurons We’ve spoken in the past about the power of worms: C. elegans models were used by Dr.

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How Machine Learning Drives Clinical Trial Efficiency

Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.

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Nearly a Half-Million Americans Might Have Tick-Borne Meat Allergy Syndrome

Drugs.com

THURSDAY, July 27, 2023 -- Tick bites can cause crippling infections like Lyme disease in humans, but new research suggests they can also trigger a serious meat allergy in far more Americans than thought. Called alpha-gal syndrome, the condition.

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A Pediatric Experience Success Story: Opening a New Digital Front Door

Perficient: Drug Development

While entering a new and highly competitive pediatric market, our client needed to offer an excellent digital experience. The health system partnered with Perficient to build a frictionless and guided experience that patients and families both need and expect. Providing a Truly Patient-centered Experience First, we identified site KPIs, developed target personas, built a digital roadmap, and audited site content.

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Lilly adds to case for Mounjaro’s weight-loss benefits with new study data

BioPharma Drive: Drug Pricing

The results showed that enrollees who’d already lost weight after diet and exercise shed pounds after receiving Mounjaro, while those who stopped treatment gained weight back.

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Genetic variant identification: unveiling the power of STING-seq

Drug Target Review

Co-led by Dr Sanjana, the research study combines CRISPR gene editing and single-cell sequencing to identify causal genetic variants and enhance our understanding of the noncoding genome. Published in Science , the study offers new possibilities for identifying therapeutic targets in genetically influenced diseases. The workflow, which has been termed STING-seq, integrates biobank-scale GWAS data with CRISPR and single-cell sequencing techniques, allowing for the identification of target genes a

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Deliver Fast, Flexible Clinical Trial Insights with Spotfire

Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.

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Probiotics Are Good for More Than Your Gut

Drugs.com

MONDAY, July 24, 2023 -- Many people turn to probiotics for their digestive woes, but a preliminary study suggests that what's good for gut may also be good for the aging brain. The study involved older adults with mild cognitive impairment, where.

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Microsoft Viva Insights: How to Get Started Leveraging Data for Enterprise Success

Perficient: Drug Development

In today’s business landscape, enterprises are constantly seeking ways to improve employee productivity, engagement, and well-being. Microsoft’s Viva Insights, an innovative workplace analytics solution, has emerged as a powerful tool to help organizations achieve these goals. By providing valuable data-driven insights, Viva Insights enables enterprises to make informed decisions that foster a more productive and thriving work environment.

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Merck, chasing Pfizer, claims study success for new pneumonia vaccine

BioPharma Drive: Drug Pricing

The pharma said its latest shot, which covers 21 strains of bacteria, cleared two Phase 3 trials and in some cases spurred a stronger immune response than Pfizer’s Prevnar 20.

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Malaria unravelled: decoding the parasite’s gene expression control

Drug Target Review

Researchers from Tokyo Tech’s World Research Hub Initiative conducted a study to investigate the regulation of gene expression in the apicoplast of the malaria parasite Plasmodium falciparum. The results were published in Proceedings of National Academy of Sciences of United States of America (PNAS). The team, led by Professor Kan Tanaka, collaborated with scientists from Nagasaki University and the John Innes Centre in the UK.

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Clinical Data Like You´ve Never Seen It Before: Why Spotfire Is the Leading Tool for Clinical Analytics

Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic

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Olive Oil a Powerful Prescription Against Dementia

Drugs.com

MONDAY, July 24, 2023 -- People looking to stay mentally sharp as they age might want to swap out margarine for olive oil, a preliminary study suggests. The study, of more than 90,000 U.S. health professionals, found that olive oil lovers were less.

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HCL Commerce Customization Capabilities: Empowering Businesses with Tailored E-commerce Solutions

Perficient: Drug Development

Introduction: In the competitive world of e-commerce, delivering a personalized and flawless shopping experience is consummate to success, businesses face the challenge of delivering unique and individualized shopping experiences to their customers. Businesses must figure out how to give their customers distinctive and personalized purchasing experiences in the rapidly changing world of e-commerce.

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Roche buys into Alnylam heart drug in cardiovascular research bet

BioPharma Drive: Drug Pricing

The Swiss pharma company is the latest large drugmaker to invest big in an experimental heart treatment, after years of prioritizing medicines for cancer and immune diseases.

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Imaging shows how solar-powered microbes turn CO2 into bioplastic

SCIENMAG: Medicine & Health

ITHACA, N.Y. – When considering ways to sustainably generate environmentally friendly products, bacteria might not immediately spring to mind. However, in recent years scientists have created microbe-semiconductor biohybrids that merge the biosynthetic power of living systems with the ability of semiconductors to harvest light.

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Classifying Chemicals Toxicity during Drug Discovery

biobide

In Drug Discovery and Development, the determination and classification of chemical toxicity plays a pivotal role in shaping pharmaceutical development while ensuring the safety of patients. The categorization of these hazardous substances not only helps researchers identify potential risks but also provides them with a guide in the arduous journey of Drug Discovery and Development.

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Unleashing Your Data Potential: Why Fusion Analytics Warehouse Might Be The Perfect Fit

Perficient: Drug Development

In today’s data-driven world, organizations face the challenge of efficiently managing the mountains of data gained over their years of operation. This has led to the emergence of advanced analytics solutions that can turn raw data into actionable intelligence. Oracle’s answer to this call of action is Fusion Analytics Warehouse (FAW). In this blog post we will explore why Fusion Analytics Warehouse might be exactly what you need.

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Biogen to acquire rare disease drugmaker Reata for $7.3B

BioPharma Drive: Drug Pricing

The deal is a major bet by Biogen and its new CEO Chris Viehbacher, who’s reorganized R&D, cut costs and laid off staff since becoming company head last year.

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Researchers Identify Genes That Influence What You Eat

Drugs.com

MONDAY, July 24, 2023 -- You’ve likely heard that "you are what you eat,” but a new study suggests what you eat also has something to do with who you are — genetically speaking. Researchers have identified nearly 500 genes that appear to.

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Breakthrough in solid-state storage innovates how biological materials are stored and handled

SCIENMAG: Medicine & Health

Scientists have developed a novel method for storing biological materials such as RNA and proteins in a solid-state. The storage in solid-state resembles the form of a pill or a tablet, which dissolves in water for on-demand use.

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What You Need to Know About GxP Independent Compliance Audits, Part 1

thought leadership

In this post, we’re going to discuss the various types of GxP Compliance Audits, internal versus independent third-party audits. the role that independent auditors play in conducting compliance assessments, and why independent audits are so important so that you can understand the significance of GxP compliance audits and make informed decisions regarding them.

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Bavarian Nordic to scrap RSV vaccine after study setback

BioPharma Drive: Drug Pricing

The shot failed to meet a key goal of Bavarian Nordic’s Phase 3 study, a finding that separates it from marketed vaccines developed by Pfizer and GSK.

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Over Half of People With Autoimmune Conditions Suffer Depression, Anxiety

Drugs.com

WEDNESDAY, July 26, 2023 -- More than half of all patients with autoimmune diseases also suffer from depression and anxiety -- but most are never asked about their mental health, a new study finds. Surveying more than 1,800 patients, British.

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A wearable ultrasound scanner could detect breast cancer earlier

SCIENMAG: Medicine & Health

CAMBRIDGE, MA — When breast cancer is diagnosed in the earliest stages, the survival rate is nearly 100 percent. However, for tumors detected in later stages, that rate drops to around 25 percent. Credit: Canan Dagdeviren CAMBRIDGE, MA — When breast cancer is diagnosed in the earliest stages, the survival rate is nearly 100 percent.

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Blogger Meets Blogger

Molecular Design

Over the years I’ve had had some cool random encounters (some years ago I bumped into a fellow member of the Macclesfield diving club in the village of Pai in the north of Thailand) but the latest is perhaps the most remarkable (even if it's not quite in the league of Safecracker Meets Safecracker in Surely You’re Joking). I was riding the Red Line on Boston’s T en route to Belmont from a conference in Vermont when my friend Ash Jogalekar, well known for The Curious Wavefunction blog , came over

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FDA declines to review Biohaven’s latest drug in setback to pipeline

BioPharma Drive: Drug Pricing

While the FDA doesn’t think the brain disease treatment merits an evaluation, Biohaven is still pushing for one and has requested a further meeting.

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