Drugs.com
AUGUST 17, 2023
THURSDAY, Aug. 17, 2023 -- Sometimes patients with pancreatic cancer are prescribed the benzodiazepine lorazepam (Ativan) for anxiety, but that may be harming their health. A new study found this treatment was linked to worse outcomes, with shorter.
BioPharma Drive: Drug Pricing
AUGUST 18, 2023
BSCA has kicked CVS Caremark, the largest pharmacy benefit manager in the country, to the curb and is electing to carve out various pharmacy functions with companies like Amazon instead.
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Collaborative Drug
AUGUST 14, 2023
Upcoming Webinar: Drug design trends in the age of AI
Science Daily: Pharmacology News
AUGUST 14, 2023
Imagine using insects as a source of chemicals to make plastics that can biodegrade later -- with the help of that very same type of bug. That concept is closer to reality than you might expect. Researchers will describe their progress to date, including the isolation and purification of the insect-derived chemicals and their conversion into their bioplastics.
Speaker: Simran Kaur, Co-founder & CEO at Tattva.Health
AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!
Drugs.com
AUGUST 18, 2023
FRIDAY, Aug. 18, 2023 -- A new COVID variant with very few known cases but many mutations has been swiftly moved into the World Health Organization’s "variant under monitoring" classification. Four known cases of the variant, dubbed BA.2.86, have.
Drug Discovery Digest brings together the best content for drug research and development professionals from the widest variety of industry thought leaders.
Collaborative Drug
AUGUST 15, 2023
Drug Discovery Industry Roundup with Barry Bunin — August 15, 2023
Drug Hunter
AUGUST 18, 2023
The First Disclosures sessions at the 2023 ACS Fall Meeting in San Francisco, organized by Nikki Goodwin , presented a variety of new orally available small molecules. The standing room-only sessions were so highly attended that many attendees were unfortunately kicked out due to the fire code. In case you missed any of these exciting molecules, from Scorpion’s mutant-selective PI3Kα inhibitor to Nurix’s CNS-penetrant BTK degrader, here we share the structures and targets of all the novel molecu
Drugs.com
AUGUST 18, 2023
FRIDAY, Aug. 18, 2023 -- Binge-drinking and marijuana use have reached historically high levels among U.S. adults aged 35 to 50, the U.S. National Institutes of Health announced Thursday. For these middle-aged adults, the drugs of choice are.
BioPharma Drive: Drug Pricing
AUGUST 16, 2023
The struggling biotech also plans to offload other cell therapy assets, including a multiple myeloma therapy, and focus exclusively on gene editing medicines.
Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.
The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven
Collaborative Drug
AUGUST 15, 2023
Company Named as a Sample Vendor for SaaS Electronic Lab Notebook San Francisco, CA - August 15, 2023 - Collaborative Drug Discovery (CDD) is proud to announce its recent recognition as a Sample Vendor for Software-as-a-Service (SaaS) Electronic Laboratory Notebook (ELN) in the Gartner Hype Cycle for Life Science Discovery Research, 2023 report. Gartner Hype Cycles provide a graphic representation of the maturity and adoption of technologies and applications, and how they are potentially relevan
Drug Hunter
AUGUST 15, 2023
LRRK2 has been a hotly pursued drug target for Parkinson’s Disease based on human genetics. Clinical advancement of LRRK2 inhibitors was initially stalled by concerns about on-target lung findings in primates, but these were ameliorated by a Merck/Genentech/Pfizer/MJFF study showing that these lung changes were reversible, and Biogen/Denali has currently a small molecule (BIIB122/DNL151) in Ph.
Drugs.com
AUGUST 18, 2023
FRIDAY, Aug. 18, 2023 -- Phillip Durst was working near an industrial dishwasher when something went awry, and the machinery spewed caustic chemicals into his eyes. “If I had been standing a foot left or right, it wouldn't have hit me right where.
BioPharma Drive: Drug Pricing
AUGUST 15, 2023
More than a dozen startups have joined a few publicly traded biotechs and larger pharmaceutical firms in what’s become one of the most competitive areas in drug research.
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Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.
Collaborative Drug
AUGUST 15, 2023
Company Named as a Sample Vendor for SaaS Electronic Lab Notebook San Francisco, CA - August 15, 2023 - Collaborative Drug Discovery (CDD) is proud to announce its recent recognition as a Sample Vendor for Software-as-a-Service (SaaS) Electronic Laboratory Notebook (ELN) in the Gartner Hype Cycle for Life Science Discovery Research, 2023 report. Gartner Hype Cycles provide a graphic representation of the maturity and adoption of technologies and applications, and how they are potentially relevan
Science Daily: Pharmacology News
AUGUST 18, 2023
A new study has demonstrated that the atlatl (i.e. spear thrower) functions as an 'equalizer', a finding which supports women's potential active role as prehistoric hunters.
Drugs.com
AUGUST 17, 2023
THURSDAY, Aug. 17, 2023 -- Public health officials are warning people about the risks of flesh-eating bacterial infections and how to avoid them after the deaths of three older adults on the northeast coast. Two of the deaths from vibriosis — an.
BioPharma Drive: Drug Pricing
AUGUST 15, 2023
The agency had paused testing after a patient death, but is now permitting more types of bridging treatment to help keep participants’ disease at bay.
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Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.
Covalent Modifiers
AUGUST 14, 2023
Heta S Desai, Samuel Ofori, Lisa M Boatner, Fengchao Yu, Miranda Villaneuva, Nicholas Ung, Alexey Nesvizhskii, Keriann M Backus doi: [link] Cancer genomes are rife with genetic variants; one key outcome of this variation is gain-of-cysteine, which is the most frequently acquired amino acid due to missense variants in COSMIC. Acquired cysteines are both driver mutations and sites targeted by precision therapies.
Science Daily: Pharmacology News
AUGUST 17, 2023
In 1956, theoretical physicists predicted that electrons in a solid can do something strange. While they normally have a mass and an electric charge, Pines asserted that they can combine to form a composite particle that is massless, neutral, and does not interact with light. He called this particle a 'demon.' Since then, it has been speculated to play an important role in the behaviors of a wide variety of metals.
Drugs.com
AUGUST 17, 2023
THURSDAY, Aug. 17, 2023 -- A new type of medication, JAK inhibitors, can effectively treat moderate to severe alopecia areata, a hair loss condition that has been historically hard to treat. A study of its effectiveness, by Dr. Brett King and Dr.
BioPharma Drive: Drug Pricing
AUGUST 14, 2023
Elrexfio is the third bispecific antibody cleared to treat the blood cancer, and will compete with other therapies that target the “BCMA” protein on myeloma cells.
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Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic
Chemical Biology and Drug Design
AUGUST 13, 2023
Flow diagram of KCLW's network pharmacology. Abstract KeChuanLiuWei-Mixture (KCLW) is widely used as a Chinese medicine prescription to treat severe asthma. However, the underlying therapeutic mechanism of KCLW remains unclear. In this study, a network pharmacology method was used to identify the chemical constituents of KCLW by the TCMSP database and ultra-performance liquid chromatography coupled with time-of-flight mass spectrometry.
Science Daily: Pharmacology News
AUGUST 17, 2023
Researchers have found an injection of a specific blood factor can replicate the benefits of exercise in the brain. They've discovered that platelets secrete a protein, exerkine CXCL4/Platelet factor 4 or PF4, that rejuvenates neurons in aged mice in a similar way to physical exercise. This protein, which is released from platelets after exercise, results in regenerative and cognitive improvements when injected into aged mice.
Drugs.com
AUGUST 17, 2023
THURSDAY, Aug. 17, 2023 -- Despite what you see on TikTok, don’t consume the laundry powder borax to relieve pain and inflammation or boost bone health. Even though videos on the social media site tout it as a treatment, this substance is not safe.
BioPharma Drive: Drug Pricing
AUGUST 14, 2023
Meet the pharma marketer of the future, primed for personalization and powered by technology.
Chemical Biology and Drug Design
AUGUST 12, 2023
A water-soluble polysaccharide (GFP) was isolated from Grateloupia filicina and its structure was thoroughly examined. Among the polysaccharides, a purified GFP-1 significantly increased the activation of RAW264.7 cells by releasing nitric oxide (NO) and a variety of cytokines via NF-B and MAPK signaling pathways via TLR-2 and TLR-4 binding receptors.
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