Drug Discovery World
AUGUST 29, 2023
The pharmaceutical industry continues to maintain strong levels of public trust and favourability in the UK, according to data from the Association of the British Pharmaceutical Industry (ABPI). Opinions showed consistent recognition of the sector’s support for the NHS, with 67% of respondents saying the industry is committed to developing new medicines to meet patient needs.
Broad Institute
AUGUST 31, 2023
Evolved prime editors are smaller and more efficient for therapeutic applications By Corie Lok August 31, 2023 Breadcrumb Home Evolved prime editors are smaller and more efficient for therapeutic applications Researchers have evolved the editing machine at the heart of the prime editing system, which can make a wide range of changes to the genome. By Sarah C.P.
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Drugs.com
SEPTEMBER 1, 2023
FRIDAY, Sept. 1, 2023 -- A growing number of overdose deaths in the United States involve counterfeit pills, health officials reported Thursday. Overdose deaths involving counterfeit pills were twice as common in the latter half of 2021 as they were.
Science Daily: Pharmacology News
SEPTEMBER 1, 2023
A new study finds that farmers in India have adapted to warming temperatures by intensifying the withdrawal of groundwater used for irrigation. If the trend continues, the rate of groundwater loss could triple by 2080, further threatening India's food and water security. Reduced water availability in India due to groundwater depletion and climate change could threaten the livelihoods of more than one-third of the country's 1.4 billion residents and has global implications.
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Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.
Drug Discovery World
SEPTEMBER 1, 2023
News round-up for 28 August – 1 September by DDW Digital Content Editor Diana Spencer. This week’s headline news features a stem-cell derived Parkinson’s therapy, a monoclonal antibody for head and neck cancer, an estrogen receptor degrader for breast cancer, a mitochondrial activator for long Covid, and the world’s first AI-designed bispecific T cell engager – reflecting the breadth of innovative approaches to disease being employed by researchers across the globe.
BioPharma Drive: Drug Pricing
AUGUST 31, 2023
Houman Ashrafian, currently a scientific advisor at SV Health Investors, will fill the role left by John Reed, who oversaw the transformation of research and development during his five years at Sanofi.
Drug Discovery Digest brings together the best content for drug research and development professionals from the widest variety of industry thought leaders.
Antidote
AUGUST 30, 2023
At the outset, many people may experience apprehension when considering joining a clinical trial. Opting to participate in a research study is a personal one — but it can also be quite gratifying. Various types of clinical studies play a pivotal role in ensuring the approval of life-saving medications and treatments. For this to happen, we need volunteers to take part.
Drug Discovery World
SEPTEMBER 1, 2023
A new study has provided insights into the biological mechanism that supports survival of hard-to-treat cancers. In the new study, led by scientists at The Institute of Cancer Research and published in Nature Communications , researchers identify a new cellular role of a protein called EXD2 nuclease and, importantly, its role in the so-called ALT (alternative lengthening of telomeres) pathway.
BioPharma Drive: Drug Pricing
AUGUST 29, 2023
A broadened clearance for Reblozyl in myelodysplastic syndromes should help Bristol Myers offset the looming loss of revenue from top-selling medicines set to soon lose market exclusivity.
Drugs.com
AUGUST 30, 2023
WEDNESDAY, Aug. 30, 2023 -- Narcan, a lifesaving medication that reverses opioid overdose, will be available on U.S. drugstore shelves and online starting next week. People who want to carry Narcan, the nasal spray version of naloxone, will be able.
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Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.
NIOSH Science Blog: Drugs
SEPTEMBER 1, 2023
Labor Day often evokes thoughts about the end of summer and start of a new school year. It can be easy to forget that the origins of the holiday lie in the labor movement of the late nineteenth century when workers fought for their rights, including safer working conditions. A lot has changed since then and while we have made significant progress in improving worker safety and health, new challenges continue to arise as work and workplaces evolve.
Drug Discovery World
AUGUST 31, 2023
Arvinas and Pfizer UK have been awarded a UK Innovation Passport for vepdegestrant (ARV-471), an investigational PROTAC ER (estrogen receptor) degrader. It is intended for the treatment of patients with oestrogen receptor (ER)+/ human epidermal growth factor receptor (HER)2- locally-advanced breast cancer or metastatic breast cancer. The Innovation Passport is the entry point for the Innovative Licensing and Access Pathway (ILAP).
BioPharma Drive: Drug Pricing
AUGUST 31, 2023
Two founding executives are leaving Sage alongside a major restructuring announced weeks after the FDA approved the medicine, Zurzuvae, for much narrower use than the company had hoped.
Drugs.com
AUGUST 31, 2023
THURSDAY, Aug. 31, 2023 -- When factoring in why children get asthma, a child's neighborhood may be important to consider. New research finds that living in a neighborhood during early childhood that has better access to resources was associated.
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Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic
Drug Patent Watch
SEPTEMBER 1, 2023
Annual Drug Patent Expirations for SPY+AGENT+GREEN+KIT Spy Agent Green Kit is a drug marketed by Novadaq Tech and is included in one NDA. It is available from one supplier. There… The post New patent for Novadaq Tech drug SPY AGENT GREEN KIT appeared first on DrugPatentWatch - Make Better Decisions.
Drug Target Review
SEPTEMBER 1, 2023
Could you explain the fundamental distinction between autologous and allogeneic cell therapies and how they differ in terms of cell sourcing and application? Autologous immune cell therapy involves the grafting of a patient’s own immune cells. During this approach, immune cells are collected from a patient and expanded ex vivo to produce cells in large numbers that are ideally healthy and highly functional.
BioPharma Drive: Drug Pricing
SEPTEMBER 1, 2023
The Swiss pharma said, without details, that it observed “unprecedented” results that could make Alecensa the first treatment specifically available after surgery for ALK-positive lung tumors.
Drugs.com
AUGUST 30, 2023
WEDNESDAY, Aug. 30, 2023 -- Sudden cardiac arrest may not come on so suddenly after all. Fully 50% of people who experienced a sudden cardiac arrest had a telling symptom 24 hours before, and these symptoms are different in men than women, a new.
Perficient: Drug Development
AUGUST 31, 2023
Responsibilities, Skills, Scope and More. The tutorial provides basic concepts of Kotlin. Our Kotlin tutorial includes. What is Kotlin? Pre-Requisites Features of Kotlin Kotlin Architecture What is Kotlin? Kotlin is a programming language introduced by JetBrains in 2011. Kotlin is free, has been free and will remain free. It is developed under the Apache 2.0 license.
Drug Target Review
AUGUST 31, 2023
In the pursuit of a remedy for Alzheimer’s disease, a frontier in medical science is illuminating a glimmer of hope. Stem cell therapies have already demonstrated their prowess in treating diverse cancers and ailments linked to the blood and immune system. In an innovative proof-of-concept investigation, researchers at the University of California San Diego have revealed the potential of stem cell transplants as a promising therapeutic avenue against Alzheimer’s disease.
BioPharma Drive: Drug Pricing
AUGUST 29, 2023
The list includes the top-selling blood thinners Eliquis and Xarelto, as well as the arthritis drug Enbrel and heart failure medicine Entresto.
Drugs.com
AUGUST 31, 2023
THURSDAY, Aug. 31, 2023 -- If a loved one were living with addiction, a majority of Americans say they would know how to get help. About 71% of 2,200 respondents to an American Psychiatric Association poll said they would know how to assist a friend.
Perficient: Drug Development
AUGUST 28, 2023
Introduction to Feign Client: In the world of software, microservices are like building blocks that help make programs more flexible and scalable. But for these blocks to work together, they need to talk to each other effectively. Imagine each block sharing information, asking for help, and working together smoothly. Meet Feign Client, a super useful tool for microservices.
biobide
SEPTEMBER 1, 2023
Angiogenesis is a dynamic process by which blood vessels grow from pre-existing ones. The initial network is set up by vasculogenesis, the process of de novo formation of vessels, and becomes modified and grows by angiogenesis. Unlike most other organs, vasculature has a remarkable capacity to regenerate, and grow also in the adult organism, to efficiently repair damaged tissues.
Translation
AUGUST 31, 2023
Halo was proud to host Bayer Crop Science ’s third year of Grants4Ag. Grants4Ag is Bayer’s annual initiative providing funding and expertise to researchers developing novel solutions in agriculture. As part of Bayer’s CropKey approach to crop protection innovation, this year’s awards focused on transformative R&D and breakthrough technologies for next-gen crop protection solutions.
Drugs.com
AUGUST 28, 2023
MONDAY, Aug. 28, 2023 -- About half of older adults (52 percent) have heard of the new vaccines against respiratory syncytial virus (RSV), Arexvy and Abrysvo, according to the National Poll on Healthy Aging released online on Aug. 22.
BioPharma Drive: Drug Pricing
SEPTEMBER 1, 2023
The settlement between Amgen and the FTC may reassure those in the industry who feared a more activist regulator would gum up dealmaking.
Perficient: Drug Development
AUGUST 28, 2023
An innovation wildcard is a team member who is there to add a unique perspective that the rest of the team may not have. This person can be within the organization or pulled from outside. They may have deep expertise in other areas, or they may be new and more likely to question everything. Innovation demands new ideas and ways of thinking. Adding a wildcard player to the team will help the creativity process.
Drug Patent Watch
AUGUST 28, 2023
In a guest column Kevin Wall, principal consultant and owner of Cincero Consulting, emphasizes the critical importance of selecting the right Contract Development and Manufacturing Organization (CDMO) for drug product… The post Key Factors for Choosing the Right CDMO appeared first on DrugPatentWatch - Make Better Decisions.
Drugs.com
AUGUST 31, 2023
THURSDAY, Aug. 31, 2023 -- A type of gene therapy that precisely "edits" a key bit of DNA might offer a new way to treat sickle cell disease -- a painful inherited condition that largely strikes Black children and adults. That's according to a new.
BioPharma Drive: Drug Pricing
AUGUST 28, 2023
Urged by a judge, the antitrust regulator said it wants to start discussions “regarding the proper resolution of this matter” — a potential prelude to a settlement.
SCIENMAG: Medicine & Health
AUGUST 29, 2023
In a world experiencing increased heat stress, a zero-carbon-emission cooling technology that consumes no electricity, operating instead by shedding heat directly into outer space, would be a groundbreaking advance. However, poor standardization and a lack of transparency is hampering this promising technology, known as radiative cooling.
Antidote
SEPTEMBER 1, 2023
As part of our efforts to better understand patients and their motivations to participate in clinical trials, Antidote and SCORR Marketing partnered on a survey to gain a deeper understanding of how patients think about the medical research process. Survey participants were recruited by eight of Antidote’s partners, including the American Kidney Fund, Allergy & Asthma Network, Healthline, JDRF, Lung Cancer Alliance, Lupus Research Alliance, Melanoma Research Alliance, and the Multiple Sclero
Drugs.com
SEPTEMBER 1, 2023
FRIDAY, Sept. 1, 2023 -- Float therapy, where a patient is suspended in a pool of warm, salty water in a soundproof room, could help ease some aspects of anorexia nervosa, a small new study found. “The idea is that women with anorexia have.
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