Broad Institute
AUGUST 31, 2023
Evolved prime editors are smaller and more efficient for therapeutic applications By Corie Lok August 31, 2023 Breadcrumb Home Evolved prime editors are smaller and more efficient for therapeutic applications Researchers have evolved the editing machine at the heart of the prime editing system, which can make a wide range of changes to the genome. By Sarah C.P.
Drugs.com
SEPTEMBER 1, 2023
FRIDAY, Sept. 1, 2023 -- A growing number of overdose deaths in the United States involve counterfeit pills, health officials reported Thursday. Overdose deaths involving counterfeit pills were twice as common in the latter half of 2021 as they were.
Science Daily: Pharmacology News
SEPTEMBER 1, 2023
A new study finds that farmers in India have adapted to warming temperatures by intensifying the withdrawal of groundwater used for irrigation. If the trend continues, the rate of groundwater loss could triple by 2080, further threatening India's food and water security. Reduced water availability in India due to groundwater depletion and climate change could threaten the livelihoods of more than one-third of the country's 1.4 billion residents and has global implications.
Antidote
AUGUST 30, 2023
At the outset, many people may experience apprehension when considering joining a clinical trial. Opting to participate in a research study is a personal one — but it can also be quite gratifying. Various types of clinical studies play a pivotal role in ensuring the approval of life-saving medications and treatments. For this to happen, we need volunteers to take part.
Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.
The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven
Broad Institute
AUGUST 31, 2023
Schizophrenia gene mutation causes many changes in the mouse brain By Leah Eisenstadt August 31, 2023 Breadcrumb Home Schizophrenia gene mutation causes many changes in the mouse brain A study of a genetic mouse model of schizophrenia supports two long-debated hypotheses, and unveils additional new clues about the biological roots of the disorder. By Leah Eisenstadt August 31, 2023 Credit: Susanna Hamilton, Broad Communications Researchers studied the effects of a schizophrenia gene mutation in
Drugs.com
AUGUST 31, 2023
THURSDAY, Aug. 31, 2023 – The U.S. Department of Health and Human Services has asked the U.S. Drug Enforcement Agency to reclassify marijuana as a less dangerous drug under the Controlled Substances Act, a move that could potentially expand.
Drug Discovery Digest brings together the best content for drug research and development professionals from the widest variety of industry thought leaders.
NIOSH Science Blog: Drugs
SEPTEMBER 1, 2023
Labor Day often evokes thoughts about the end of summer and start of a new school year. It can be easy to forget that the origins of the holiday lie in the labor movement of the late nineteenth century when workers fought for their rights, including safer working conditions. A lot has changed since then and while we have made significant progress in improving worker safety and health, new challenges continue to arise as work and workplaces evolve.
Drug Target Review
SEPTEMBER 1, 2023
Could you explain the fundamental distinction between autologous and allogeneic cell therapies and how they differ in terms of cell sourcing and application? Autologous immune cell therapy involves the grafting of a patient’s own immune cells. During this approach, immune cells are collected from a patient and expanded ex vivo to produce cells in large numbers that are ideally healthy and highly functional.
Drugs.com
AUGUST 30, 2023
WEDNESDAY, Aug. 30, 2023 -- Narcan, a lifesaving medication that reverses opioid overdose, will be available on U.S. drugstore shelves and online starting next week. People who want to carry Narcan, the nasal spray version of naloxone, will be able.
BioPharma Drive: Drug Pricing
AUGUST 29, 2023
A broadened clearance for Reblozyl in myelodysplastic syndromes should help Bristol Myers offset the looming loss of revenue from top-selling medicines set to soon lose market exclusivity.
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Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.
Perficient: Drug Development
AUGUST 31, 2023
Responsibilities, Skills, Scope and More. The tutorial provides basic concepts of Kotlin. Our Kotlin tutorial includes. What is Kotlin? Pre-Requisites Features of Kotlin Kotlin Architecture What is Kotlin? Kotlin is a programming language introduced by JetBrains in 2011. Kotlin is free, has been free and will remain free. It is developed under the Apache 2.0 license.
Drug Target Review
AUGUST 30, 2023
Advancing drug discovery for pain disorders: human iPSC-based approach Drug discovery relies on the use of relevant model systems. Most new targets have been discovered using animal models, which while useful, are not sufficiently predictive of human safety and efficacy. We have developed a unique approach for using human induced pluripotent stem cells for target validation from a list of targets from real-world data and whole-genome sequencing.
Drugs.com
AUGUST 30, 2023
WEDNESDAY, Aug. 30, 2023 -- Sudden cardiac arrest may not come on so suddenly after all. Fully 50% of people who experienced a sudden cardiac arrest had a telling symptom 24 hours before, and these symptoms are different in men than women, a new.
BioPharma Drive: Drug Pricing
AUGUST 31, 2023
Two founding executives are leaving Sage alongside a major restructuring announced weeks after the FDA approved the medicine, Zurzuvae, for much narrower use than the company had hoped.
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Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.
Perficient: Drug Development
AUGUST 28, 2023
Introduction to Feign Client: In the world of software, microservices are like building blocks that help make programs more flexible and scalable. But for these blocks to work together, they need to talk to each other effectively. Imagine each block sharing information, asking for help, and working together smoothly. Meet Feign Client, a super useful tool for microservices.
Drug Target Review
AUGUST 31, 2023
In the pursuit of a remedy for Alzheimer’s disease, a frontier in medical science is illuminating a glimmer of hope. Stem cell therapies have already demonstrated their prowess in treating diverse cancers and ailments linked to the blood and immune system. In an innovative proof-of-concept investigation, researchers at the University of California San Diego have revealed the potential of stem cell transplants as a promising therapeutic avenue against Alzheimer’s disease.
Drugs.com
AUGUST 28, 2023
MONDAY, Aug. 28, 2023 -- About half of older adults (52 percent) have heard of the new vaccines against respiratory syncytial virus (RSV), Arexvy and Abrysvo, according to the National Poll on Healthy Aging released online on Aug. 22.
BioPharma Drive: Drug Pricing
SEPTEMBER 1, 2023
The Swiss pharma said, without details, that it observed “unprecedented” results that could make Alecensa the first treatment specifically available after surgery for ALK-positive lung tumors.
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Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic
biobide
SEPTEMBER 1, 2023
Angiogenesis is a dynamic process by which blood vessels grow from pre-existing ones. The initial network is set up by vasculogenesis, the process of de novo formation of vessels, and becomes modified and grows by angiogenesis. Unlike most other organs, vasculature has a remarkable capacity to regenerate, and grow also in the adult organism, to efficiently repair damaged tissues.
Translation
AUGUST 31, 2023
Halo was proud to host Bayer Crop Science ’s third year of Grants4Ag. Grants4Ag is Bayer’s annual initiative providing funding and expertise to researchers developing novel solutions in agriculture. As part of Bayer’s CropKey approach to crop protection innovation, this year’s awards focused on transformative R&D and breakthrough technologies for next-gen crop protection solutions.
Drugs.com
AUGUST 31, 2023
THURSDAY, Aug. 31, 2023 -- When factoring in why children get asthma, a child's neighborhood may be important to consider. New research finds that living in a neighborhood during early childhood that has better access to resources was associated.
BioPharma Drive: Drug Pricing
AUGUST 29, 2023
The list includes the top-selling blood thinners Eliquis and Xarelto, as well as the arthritis drug Enbrel and heart failure medicine Entresto.
Drug Target Review
AUGUST 29, 2023
Can you tell us about your journey in the field of STEM and the challenges you encountered along the way? My STEM journey started with a genuine love for biology back in middle school. As I progressed through high school and then Haverford College, I got hands-on lab experience at other institutions like the NIH-NCI and the Bio21 institute in Melbourne, Australia.
Perficient: Drug Development
AUGUST 28, 2023
An innovation wildcard is a team member who is there to add a unique perspective that the rest of the team may not have. This person can be within the organization or pulled from outside. They may have deep expertise in other areas, or they may be new and more likely to question everything. Innovation demands new ideas and ways of thinking. Adding a wildcard player to the team will help the creativity process.
Drugs.com
AUGUST 31, 2023
THURSDAY, Aug. 31, 2023 -- If a loved one were living with addiction, a majority of Americans say they would know how to get help. About 71% of 2,200 respondents to an American Psychiatric Association poll said they would know how to assist a friend.
BioPharma Drive: Drug Pricing
AUGUST 28, 2023
Urged by a judge, the antitrust regulator said it wants to start discussions “regarding the proper resolution of this matter” — a potential prelude to a settlement.
Drug Patent Watch
SEPTEMBER 1, 2023
Annual Drug Patent Expirations for SPY+AGENT+GREEN+KIT Spy Agent Green Kit is a drug marketed by Novadaq Tech and is included in one NDA. It is available from one supplier. There… The post New patent for Novadaq Tech drug SPY AGENT GREEN KIT appeared first on DrugPatentWatch - Make Better Decisions.
SCIENMAG: Medicine & Health
AUGUST 29, 2023
In a world experiencing increased heat stress, a zero-carbon-emission cooling technology that consumes no electricity, operating instead by shedding heat directly into outer space, would be a groundbreaking advance. However, poor standardization and a lack of transparency is hampering this promising technology, known as radiative cooling.
Drugs.com
AUGUST 31, 2023
THURSDAY, Aug. 31, 2023 -- A type of gene therapy that precisely "edits" a key bit of DNA might offer a new way to treat sickle cell disease -- a painful inherited condition that largely strikes Black children and adults. That's according to a new.
BioPharma Drive: Drug Pricing
AUGUST 28, 2023
GPCRs, a ubiquitous family of proteins that are prime drug targets, have drawn the interest of companies like Structure Therapeutics, Septerna and now Superluminal Medicines.
Antidote
SEPTEMBER 1, 2023
As part of our efforts to better understand patients and their motivations to participate in clinical trials, Antidote and SCORR Marketing partnered on a survey to gain a deeper understanding of how patients think about the medical research process. Survey participants were recruited by eight of Antidote’s partners, including the American Kidney Fund, Allergy & Asthma Network, Healthline, JDRF, Lung Cancer Alliance, Lupus Research Alliance, Melanoma Research Alliance, and the Multiple Sclero
addgene Blog
AUGUST 31, 2023
I often wonder about the gut-brain axis (admittedly for self-serving reasons – I want to understand my obsession with the combination of chocolate and peanut butter), but it ’ s an undeniably difficult connection to study on a molecular level. The brain is constantly influenced by signals it receives from the entire body, making it difficult to probe due to the lack of tools to continuously monitor it.
Drugs.com
SEPTEMBER 1, 2023
FRIDAY, Sept. 1, 2023 -- Float therapy, where a patient is suspended in a pool of warm, salty water in a soundproof room, could help ease some aspects of anorexia nervosa, a small new study found. “The idea is that women with anorexia have.
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