Science Daily: Pharmacology News
AUGUST 14, 2024
A new brain-computer interface translates brain signals into speech with up to 97 percent accuracy. Researchers implanted sensors in the brain of a man with severely impaired speech due to amyotrophic lateral sclerosis (ALS). The man was able to communicate his intended speech within minutes of activating the system.
Chemical Biology and Drug Design
AUGUST 16, 2024
Baicalein (BE) augments radiosensitivity in colorectal cancer (CRC) by inhibiting the JAK2/STAT3 pathway. In vitro and in vivo experiments demonstrate BE's ability to enhance apoptosis and suppress PD-L1 expression, suggesting its potential as a radiosensitizer in CRC therapy. ABSTRACT Radiation resistance is a crucial factor influencing therapeutic outcomes in colorectal cancer (CRC).
ASPET
AUGUST 12, 2024
Neuropathic pain is a form of chronic pain that develops because of damage to the nervous system. Treatment of neuropathic pain is often incompletely effective, and most available therapeutics have only moderate efficacy and present side effects that limit their use. Opioids are commonly prescribed for the management of neuropathic pain despite equivocal results in clinical studies and significant abuse potential.
Drugs.com
AUGUST 16, 2024
FRIDAY, Aug. 16, 2024 -- As syphilis cases surge throughout the United States, the U.S. Food and Drug Administration on Friday approved the first diagnostic at-home test to spot the bacterial disease."This is the first at-home, over-the-counter.
Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.
The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven
Science Daily: Pharmacology News
AUGUST 13, 2024
Linked to cardiovascular and respiratory diseases in people, nanoplastics continue to build up, largely unnoticed, in the world's bodies of water. The challenge remains to develop a cost-effective solution to get rid of nanoplastics while leaving clean water behind. That's where Mizzou comes in. Recently, researchers created a new liquid-based solution that eliminates more than 98% of these microscopic plastic particles from water.
Chemical Biology and Drug Design
AUGUST 15, 2024
The findings reveal the active constituents, key targets, and molecular mechanisms of myrrh in BC treatment, providing scientific evidence that supports the role of myrrh in BC therapy. ABSTRACT This study aimed to investigate the mechanism of action of myrrh in breast cancer (BC) treatment and identify its effective constituents. Data on the compounds and targets of myrrh were collected from the TCMSP, PubChem, and Swiss Target Prediction databases.
Drug Discovery Digest brings together the best content for drug research and development professionals from the widest variety of industry thought leaders.
Drugs.com
AUGUST 12, 2024
MONDAY, Aug. 12, 2024 -- Advocates for the use of the psychedelic drug MDMA (midomafetamine) to treat mental health conditions were delivered a setback on Friday after the U.S. Food and Drug Administration declined to approve it as treatment for.
Science Daily: Pharmacology News
AUGUST 15, 2024
Scientists have restored the brain's waste-clearing process in aging mice, offering potential new treatment for Alzheimer's and Parkinson's using existing drugs.
Drug Target Review
AUGUST 16, 2024
Can you tell us about your journey in the field of STEM and the challenges you encountered along the way? I grew up in California where I developed a natural curiosity to understand how a living organism functions. Majoring in physiology in college allowed me to nourish this interest, and I knew medicine would be my path as it enabled me to learn the structure and function of the human body.
BioPharma Drive: Drug Pricing
AUGUST 16, 2024
The vaccine didn’t spur a strong enough immune response against a particular flu strain in a Phase 3 trial, leading the companies to ponder adjustments.
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Clinical trial data management is increasingly challenging as studies grow in complexity. Quickly accessing and analyzing study data is vital for assessing trial progress and patient safety. In this paper, we explore real-time data access and analysis for proactive study management. We investigate using adverse event (AE) data to monitor safety and discuss a clinical analytics platform that supports collaboration and data review workflows.
Drugs.com
AUGUST 16, 2024
FRIDAY, Aug. 16, 2024 -- There are clues that red and processed meats could be driving the increased risk of colon cancer in young adults, a new study claims.Younger colon cancer patients typically have higher levels of metabolites created by the.
Science Daily: Pharmacology News
AUGUST 14, 2024
Researchers have developed a smart fabric that can convert body heat and solar energy into electricity, potentially enabling continuous operation with no need for an external power source. Different sensors monitoring temperature, stress, and more can be integrated into the material.
Perficient: Drug Development
AUGUST 15, 2024
At Perficient, we take immense pride in igniting positive change around the world. Since Perficient’s Giving Employee Resource Group (ERG) launching the Perficient Global Grants Program earlier this year, we have seen remarkable enthusiasm and commitment from our global colleagues, each championing their favorite charitable causes with passion and purpose.
BioPharma Drive: Drug Pricing
AUGUST 12, 2024
Editors at Psychopharmacology cited "unethical conduct" that the study authors didn't disclose when submitting the papers. Lykos Therapeutics says it filed a complaint with a third party to review the way the journal came to its decision.
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Clinical research has entered a new era, one that requires real-time analytics and visualization to allow trial leaders to work collaboratively and to develop, at the click of a mouse, deep insights that enable proactive study management. Learn how Revvity Signals helps drug developers deliver clinical trial data insights in real-time using a fast and flexible data and analytics platform to empower data-driven decision-making.
Drugs.com
AUGUST 15, 2024
THURSDAY, Aug. 15, 2024 -- Ovarian cancer is known as a "silent killer," since by the time symptoms arise the disease has often already spread.But in certain cases of aggressive ovarian cancer, symptoms do arise in the tumor's early stages. In.
Science Daily: Pharmacology News
AUGUST 15, 2024
In humans, the process of learning is driven by different groups of cells in the brain firing together. For instance, when the neurons associated with the process of recognizing a dog begin to fire in a coordinated manner in response to the cells that encode the features of a dog -- four legs, fur, a tail, etc. -- a young child will eventually be able to identify dogs going forward.
Perficient: Drug Development
AUGUST 12, 2024
In the realm of enterprise integration, choosing the right platform is crucial for ensuring seamless connectivity between diverse applications and systems. Azure Integration Services (AIS) and MuleSoft are two prominent players in this field. Azure Integration Services is a cloud-based integration platform provided by Microsoft, while MuleSoft is an integration platform that allows developers to connect applications, data, and devices.
BioPharma Drive: Drug Pricing
AUGUST 15, 2024
The layoffs are part of a larger reorganization that will also see the departure of Lykos’ founder, the psychedelics advocate Rick Doblin.
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Clinical development organizations face a wide array of challenges when it comes to data, many of which can impact the operational effectiveness of their clinical trials. In this whitepaper, experts from Revvity Signals explore how solutions like TIBCO® Spotfire® enable better, more streamlined studies. The whitepaper also features a success story from Ambrx, a leading biopharmaceutical company, detailing how it has leveraged Spotfire to tackle data quality and collaboration challenges in clinic
Drugs.com
AUGUST 16, 2024
FRIDAY, Aug. 16, 2024 -- A good night’s sleep is crucial for helping people make new memories, a new study says.Neurons that capture new memories during the day reset while you sleep, researchers reported Aug. 15 in the journal Science.“This mec.
Science Daily: Pharmacology News
AUGUST 16, 2024
Barely audible to human ears, healthy soils produce a cacophony of sounds in many forms -- a bit like an underground rave concert of bubble pops and clicks. Special recordings made by ecologists show this chaotic mixture of soundscapes can be a measure of the diversity of tiny living animals in the soil, which create sounds as they move and interact with their environment.
Collaborative Drug
AUGUST 16, 2024
Burlingame, CA (USA), Kyiv (Ukraine) – August 16, 2024 — Collaborative Drug Discovery (CDD), a leader in providing scientific informatics solutions, announced today that its flagship platform, CDD Vault , now includes the complete compound collection of Enamine , a leading provider of chemical compounds and early discovery services, within its AI module for structural similarity searches.
BioPharma Drive: Drug Pricing
AUGUST 12, 2024
The clearance of Yorvipath for hypoparathyroidism was some time coming for Ascendis, which had resubmitted after receiving a rejection last year.
Drugs.com
AUGUST 14, 2024
WEDNESDAY, Aug. 14, 2024 -- Chemicals commonly found in sunscreen, makeup and other personal care products could be putting pregnancies at risk, a new study warns. Phenols and parabens in these products increase a pregnant woman’s risk of.
Science Daily: Pharmacology News
AUGUST 12, 2024
Large Language Models (LLMs) are entirely controllable through human prompts and lack 'emergent abilities'; that is, the means to form their own insights or conclusions. Increasing model size does not lead LLMs to gain emergent reasoning abilities, meaning they will not develop hazardous abilities and therefore do not pose an existential threat. A new study sheds light on the (until now unexplained) capabilities and shortcomings of LLMs, including the need for carefully engineered prompts to exh
Collaborative Drug
AUGUST 15, 2024
Inventory Search Interface: The new CDD Vault Inventory tab can be enabled by the CDD Support Team. If you wish to enable this tab in your Vault please have your vault administrator contact support@collaborativedrug.com.
BioPharma Drive: Drug Pricing
AUGUST 12, 2024
Results from a Phase 3 study could help Pfizer broaden use of its vaccine Abrysvo to younger adults whose medical history puts them at higher risk.
Drugs.com
AUGUST 13, 2024
TUESDAY, Aug. 13, 2024 -- Female patients are consistently less likely to receive painkillers than men with similar complaints, a new study finds.An analysis of more than 21,000 patient records revealed that women across every age group are less.
Science Daily: Pharmacology News
AUGUST 14, 2024
New research found that brain scans can detect consciousness in some patients with brain injury who are unresponsive. In the study, 241 participants with severe brain injury who do not respond when given a simple instruction were assessed with functional MRI (fMRI), electroencephalography (EEG), or both tests, while hearing instructions, such as 'imagine opening and closing your hand.
DrugBank
AUGUST 15, 2024
Drug development is challenging, including not only the complexities of biomolecular drug mechanisms but also the convolutions of regulatory pathways and commercialization strategies. To effectively navigate this ecosystem and expedite the development of new therapies, collaboration between the pharmaceutical industry and academia is proving increasingly vital.
Conversations in Drug Development Trends
AUGUST 14, 2024
By: Simran Padam, Medical Director, Medical Affairs Personalized treatment approaches have emerged as pivotal in improving outcomes for hematological cancers. Central to this advancement are biomarkers, which are measurable indicators that signal biological processes or pathological changes within the body. They play a crucial role in tailoring hematology oncology therapeutic strategies to individual patients and have transformed personalized medicine in oncology.
Drugs.com
AUGUST 15, 2024
THURSDAY, Aug. 15, 2024 -- The World Health Organization on Wednesday made the rare move of declaring an ongoing African outbreak of mpox a global health emergency.A new clade (strain) of the virus, plus its troubling spread throughout the.
Science Daily: Pharmacology News
AUGUST 13, 2024
A computer algorithm has achieved a 98% accuracy in predicting different diseases by analyzing the color of the human tongue. The proposed imaging system can diagnose diabetes, stroke, anemia, asthma, liver and gallbladder conditions, COVID-19, and a range of vascular and gastrointestinal issues, according to new research.
addgene Blog
AUGUST 15, 2024
What do a viral vector production facility, food allergy testing lab, and the grad student down the hall from you have in common? All of them rely on standard curves in their day-to-day work. Indeed, viral vector production facilities frequently use qPCR with a standard curve to titer their viruses; food allergy labs use standard curves with ELISAs to measure allergen concentrations in food; and your friend the grad student relies on a standard in their bicinchoninic acid assay (BCA) to normaliz
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